Magnetically controlled capsule endoscopy in one-time gastro-small intestinal joint examination: a two-centre experience

Ya-Wei Liu, Yuan-Chen Wang, Jia-Hui Zhu, Xi Jiang, Wei Zhou, Jie Zhang, Zhuan Liao, En-Qiang Linghu, Ya-Wei Liu, Yuan-Chen Wang, Jia-Hui Zhu, Xi Jiang, Wei Zhou, Jie Zhang, Zhuan Liao, En-Qiang Linghu

Abstract

Background: The lesions of certain diseases are widely distributed in both stomach and small intestine, while the step-by-step strategy of gastroscopy followed by enteroscopy can be burdensome and costly. We aimed to determine if magnetically controlled capsule endoscopy (MCE) could be used in one-time gastro-small intestine (GSI) joint examination.

Methods: In this study, data of patients in Chinese PLA General Hospital and Changhai Hospital who underwent MCE GSI examination from January 2020 to August 2021 were retrospectively analysed. The primary outcome of this study was the success rate of one-time GSI joint examination, and secondary outcomes included visualization and cleanliness of gastrointestinal tract, gastrointestinal transit times, diagnostic yield and safety of MCE examination.

Results: A total of 768 patients were included. The success rate of one-time GSI joint examination was 92.58%. There were 94.92% MCEs observed > 90% gastric mucosa in the 6 anatomic landmarks. The rate of complete small bowel examination was 97.40%. The median gastric examination time, gastric transit time and small intestine transit time were 8.18 min, 63.89 min and 4.89 h, respectively. Magnetic steering of MCE significantly decreased gastric transit time (8.92 min vs. 79.68 min, P = 0.001) and increased duodenal lesion detection rate (13.47% vs. 6.26%, P = 0.001) when compared with non-magnetic steering group. Two capsules were retained and were removed by enteroscopy or spontaneously excreted.

Conclusions: MCE is feasible to complete GSI joint examination and the detection of both gastric and small intestinal diseases can be achieved simultaneously. Trial registration Clinical Trial Registration ClinicalTrials.gov, ID: NCT05069233.

Keywords: Gastric; Joint examination; Magnetically controlled capsule endoscopy; Small intestine.

Conflict of interest statement

The authors declare that they have no competing interests.

© 2022. The Author(s).

Figures

Fig. 1
Fig. 1
Positive lesions detected by MCE. a Oesophagus cancer. b Oesophagus ulcer. c Oesophagitis. d Gastric cancer. e Gastric ulcer. f Gastric polyp. g Duodenum ulcer. h Duodenitis. i Small intestine ulcer. j Parasite. k Small intestine polyp. l Small enteritis

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