Dextrins from Maize Starch as Substances Activating the Growth of Bacteroidetes and Actinobacteria Simultaneously Inhibiting the Growth of Firmicutes, Responsible for the Occurrence of Obesity

Renata Barczynska, Janusz Kapusniak, Mieczyslaw Litwin, Katarzyna Slizewska, Mieczyslaw Szalecki, Renata Barczynska, Janusz Kapusniak, Mieczyslaw Litwin, Katarzyna Slizewska, Mieczyslaw Szalecki

Abstract

Unarguably, diet has a significant impact on human intestinal microbiota. The role of prebiotics as substances supporting the maintenance of appropriate body weight and reducing the demand for energy via stimulation of the growth of beneficial microbiota of the gut and formation products such as short-chain fatty acids, is more and more often highlighted. The objective of this study was to evaluate whether dextrins from maize starch resistant to enzymatic digestion stimulate the growth of Bacteroidetes and Actinobacteria strains representing a majority of the population of colon microbiota in lean individuals and limit the growth of Firmicutes bacterial strains representing a majority of the population of colon microbiota in obese individuals. The study was conducted with the use of in vitro method, using isolates from faeces of children characterized by normal weight, overweight and obesity. It was demonstrated that dextrins from maize starch equally efficient stimulate the growth of the isolates derived from normal-weight, overweight and obese children, and therefore may be added to foods as a beneficial component stimulating growth of strains belonging to Actinobacteria and Bacteroidetes for both overweight, obese and normal-weight children.

Keywords: Bacteroidetes; Dextrin; Firmicutes; Microbiota; Prebiotics.

Figures

Fig. 1
Fig. 1
The number of tested strains isolated from faeces of overweight, obese and normal-weight children in medium supplemented with K1 dextrin. NBW normal body weight, − Average
Fig. 2
Fig. 2
The number of tested strains isolated from faeces of overweight, obese and normal-weight children in medium supplemented with K2 dextrin. NBW normal body weight, − Average

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