Guidelines for Perioperative Care in Bariatric Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations: A 2021 Update

Erik Stenberg, Luiz Fernando Dos Reis Falcão, Mary O'Kane, Ronald Liem, Dimitri J Pournaras, Paulina Salminen, Richard D Urman, Anupama Wadhwa, Ulf O Gustafsson, Anders Thorell, Erik Stenberg, Luiz Fernando Dos Reis Falcão, Mary O'Kane, Ronald Liem, Dimitri J Pournaras, Paulina Salminen, Richard D Urman, Anupama Wadhwa, Ulf O Gustafsson, Anders Thorell

Abstract

Background: This is the second updated Enhanced Recovery After Surgery (ERAS®) Society guideline, presenting a consensus for optimal perioperative care in bariatric surgery and providing recommendations for each ERAS item within the ERAS® protocol.

Methods: A principal literature search was performed utilizing the Pubmed, EMBASE, Cochrane databases and ClinicalTrials.gov through December 2020, with particular attention paid to meta-analyses, randomized controlled trials and large prospective cohort studies. Selected studies were examined, reviewed and graded according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system. After critical appraisal of these studies, the group of authors reached consensus regarding recommendations.

Results: The quality of evidence for many ERAS interventions remains relatively low in a bariatric setting and evidence-based practices may need to be extrapolated from other surgeries.

Conclusion: A comprehensive, updated evidence-based consensus was reached and is presented in this review by the ERAS® Society.

Conflict of interest statement

ES has received a speaker honorarium from Johnson & Johnson Medical. LF has received speaker honorarium from Merck Sharp & Dohme, Pfizer and Baxter. MK has received speaker honoraria and personal fees from NovoNordisk, speaker honoraria from Johnson & Johnson Medical, and is member of the IFSO Executive Board and Chair of the IFSO Integrated health Committee, Trustee of the ASO, Committee Member of the BDA Obesity Specialist Group, and Member of the Byband Sleeve Trial Management Group. RL has received speaker honorarium from Johnson & Johnson Medical, and Medtronic, and is the past president of the DSMBS. DP has received consulting fees and speaker honorarium from Johnson & Johnson Medical, speaker honorarium from Medtronic and NovoNordisk. PS has received speaker honorarium from OrionPharma and Merck, and is a member of the BEST-study data safety monitoring committee. RU reports grants and/or consulting fees from Merck, Medtronic, AcelRx, Acacia, Heron and Pfizer; grant support from NIH, NSF and AHRQ. He also reports leadership roles in the ERAS USA and ISPCOP societies. AW is the President of ISPCOP. UG is a member of the ERAS Society Executive committee. AT has received unrestricted research grants (to institution) from Ethicon Endo-Surgery, is a member of advisory board for Novo Nordisk and Ethicon Endo-Surgery and has received speakers honoraria from Kabi Fresenius and Ethicon Endo-Surgery.

© 2021. The Author(s).

References

    1. Sundbom M, Hedberg J, Marsk R, et al. Substantial decrease in comorbidity 5 years after gastric bypass: a population-based study from the scandinavian obesity surgery registry. Ann Surg. 2017;265(6):1166–1171.
    1. Schauer DP, Arterburn DE, Livingston EH, et al. Impact of bariatric surgery on life expectancy in severely obese patients with diabetes: a decision analysis. Ann Surg. 2015;261(5):914–919.
    1. Angrisani L, Santonicola A, Iovino P, Ramos A, Shikora S, Bariatric KL, Survey S. Similarities and disparities among the 5 IFSO chapters. Obes Surg. 2018;2021:1–12.
    1. Khoo CK, Vickery CJ, Forsyth N, Vinall NS, Eyre-Brook IA. A prospective randomized controlled trial of multimodal perioperative management protocol in patients undergoing elective colorectal resection for cancer. Ann Surg. 2007;245(6):867–872.
    1. Parisi A, Desiderio J, Cirocchi R, Trastulli S. Enhanced recovery after surgery (ERAS): a systematic review of randomised controlled trials (RCTs) in bariatric surgery. Obes Surg. 2020;30(12):5071–5085.
    1. Geubbels N, Evren I, Acherman YIZ, et al. Randomized clinical trial of an enhanced recovery after surgery programme versus conventional care in laparoscopic Roux-en-Y gastric bypass surgery. BJS Open. 2019;3(3):274–281.
    1. Thorell A, MacCormick AD, Awad S, et al. Guidelines for perioperative care in bariatric surgery: enhanced recovery after surgery (ERAS) society recommendations. World J Surg. 2016;40(9):2065–2083.
    1. Brindle M, Nelson G, Lobo DN, Ljungqvist O, Gustafsson UO. Recommendations from the ERAS® Society for standards for the development of enhanced recovery after surgery guidelines. BJS Open. 2020;4(1):157–163.
    1. An Glossary. In: Green SH, J, ed. Cochrane Handbook for Systematic Reviews of Interventions 4.2.5. The Cochrane Collaboration. .
    1. Guyatt GH, Oxman AD, Kunz R, et al. Going from evidence to recommendations. BMJ. 2008;336(7652):1049–1051.
    1. Guyatt GH, Oxman AD, Kunz R, Vist GE, Falck-Ytter Y, Schünemann HJ. What is "quality of evidence" and why is it important to clinicians? BMJ. 2008;336(7651):995–998.
    1. Mechanick JI, Youdim A, Jones DB, et al. Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient–2013 update: cosponsored by american association of clinical endocrinologists, the obesity society, and american society for metabolic & bariatric surgery. Obesity (Silver Spring) 2013;21(Suppl 1):S1–27.
    1. Hathaway D. Effect of preoperative instruction on postoperative outcomes: a meta-analysis. Nurs Res. 1986;35(5):269–275.
    1. Devine EC, Cook TD. A meta-analytic analysis of effects of psychoeducational interventions on length of postsurgical hospital stay. Nurs Res. 1983;32(5):267–274.
    1. Egbert LD, Battit GE, Welch CE, Bartlett MK. Reduction of postoperative pain by encouragement and instruction of patients. a study of doctor-patient rapport. N Engl J Med. 1964;270:825–827.
    1. Porras-González MH, Barón-López FJ, García-Luque MJ, Morales-Gil IM. Effectiveness of the nursing methodology in pain management after major ambulatory surgery. Pain Manag Nurs. 2015;16(4):520–525.
    1. Waller A, Forshaw K, Bryant J, Carey M, Boyes A, Sanson-Fisher R. Preparatory education for cancer patients undergoing surgery: a systematic review of volume and quality of research output over time. Patient Educ Couns. 2015;S0738–3991(15):00229–233.
    1. Koet LL, Kraima A, Derksen I, et al. Effectiveness of preoperative group education for patients with colorectal cancer: managing expectations. Support Care Cancer. 2021;29(9):5263–5271.
    1. Burgess LC, Arundel J, Wainwright TW. The effect of preoperative education on psychological, clinical and economic outcomes in elective spinal surgery: a systematic review. Healthcare Basel. 2019;7(1):48.
    1. Klaiber U, Stephan-Paulsen LM, Bruckner T, et al. Impact of preoperative patient education on the prevention of postoperative complications after major visceral surgery: the cluster randomized controlled PEDUCAT trial. Trials. 2018;19(1):288.
    1. Mechanick JI, Apovian C, Brethauer S, et al. Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures - 2019 update: cosponsored by american association of clinical endocrinologists/american college of endocrinology, the obesity society, american society for metabolic & bariatric surgery, obesity medicine association, and american society of anesthesiologists - executive summary. Endocr Pract. 2019;25(12):1346–1359.
    1. NIH conference (1991) Gastrointestinal surgery for severe obesity. Consensus Development Conference Panel. Ann Intern Med, 115(12):956–961
    1. NICE. Obesity: identification, assessment and management. Published 2014. Accessed at on May 11, 2021
    1. Rubino F, Nathan DM, Eckel RH, et al. Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations. Diabetes Care. 2016;39(6):861–877.
    1. Moller AM, Villebro N, Pedersen T, Tonnesen H. Effect of preoperative smoking intervention on postoperative complications: a randomised clinical trial. Lancet. 2002;359(9301):114–117.
    1. Haskins IN, Amdur R, Vaziri K. The effect of smoking on bariatric surgical outcomes. Surg Endosc. 2014;28(11):3074–3080.
    1. Inadomi M, Iyengar R, Fischer I, Chen X, Flagler E, Ghaferi AA. Effect of patient-reported smoking status on short-term bariatric surgery outcomes. Surg Endosc. 2018;32(2):720–726.
    1. Chow A, Neville A, Kolozsvari N. Smoking in bariatric surgery: a systematic review. Surg Endosc. 2021;35(6):3047–3066.
    1. Thomsen T, Villebro N, Moller AM. Interventions for preoperative smoking cessation. Cochrane Database Syst Rev. 2014 doi: 10.1002/14651858.CD002294.pub4.
    1. Webb AR, Coward L, Soh L, et al. Smoking cessation in elective surgical patients offered free nicotine patches at listing: a pilot study. Anaesthesia. 2020;75(2):171–178.
    1. Nath B, Li Y, Carroll JE, Szabo G, Tseng JF, Shah SA. Alcohol exposure as a risk factor for adverse outcomes in elective surgery. J Gastrointest Surg. 2010;14(11):1732–1741.
    1. Egholm JW, Pedersen B, Møller AM, Adami J, Juhl CB, Tønnesen H. Perioperative alcohol cessation intervention for postoperative complications. Cochrane Database Syst Rev. 2018;11(11):Cd008343.
    1. Kanji S, Wong E, Akioyamen L, Melamed O, Taylor VH. Exploring pre-surgery and post-surgery substance use disorder and alcohol use disorder in bariatric surgery: a qualitative scoping review. Int J Obes (Lond) 2019;43(9):1659–1674.
    1. Gils Contreras A, Bonada Sanjaume A, Montero Jaime M, et al. Effects of two preoperatory weight loss diets on hepatic volume, metabolic parameters, and surgical complications in morbid obese bariatric surgery candidates: a randomized clinical trial. Obes Surg. 2018;28(12):3756–3768.
    1. Bakker N, van den Helder RS, Geenen RWF, et al. Four weeks of preoperative omega-3 fatty acids reduce liver volume: a randomised controlled trial. Obes Surg. 2019;29(7):2037–2044.
    1. Pournaras DJ, Nygren J, Hagstrom-Toft E, Arner P, le Roux CW, Thorell A. Improved glucose metabolism after gastric bypass: evolution of the paradigm. Surg Obes Relat Dis. 2016;12(8):1457–1465.
    1. Cassie S, Menezes C, Birch DW, Shi X, Karmali S. Effect of preoperative weight loss in bariatric surgical patients: a systematic review. Surg Obes Relat Dis. 2011;7(6):760–767.
    1. Van Nieuwenhove Y, Dambrauskas Z, Campillo-Soto A, et al. Preoperative very low-calorie diet and operative outcome after laparoscopic gastric bypass: a randomized multicenter study. Arch Surg. 2011;146(11):1300–1305.
    1. Giordano S, Victorzon M. The impact of preoperative weight loss before laparoscopic gastric bypass. Obes Surg. 2014;24(5):669–674.
    1. Anderin C, Gustafsson UO, Heijbel N, Thorell A. Weight loss before bariatric surgery and postoperative complications: data from the Scandinavian Obesity Registry (SOReg) Ann Surg. 2015;261(5):909–913.
    1. Stefura T, Droś J, Kacprzyk A, et al. Influence of preoperative weight loss on outcomes of bariatric surgery for patients under the enhanced recovery after surgery protocol. Obes Surg. 2019;29(4):1134–1141.
    1. Holderbaum M, Casagrande DS, Sussenbach S, Buss C. Effects of very low calorie diets on liver size and weight loss in the preoperative period of bariatric surgery: a systematic review. Surg Obes Relat Dis. 2018;14(2):237–244.
    1. Roman M, Monaghan A, Serraino GF, et al. Meta-analysis of the influence of lifestyle changes for preoperative weight loss on surgical outcomes. Br J Surg. 2019;106(3):181–189.
    1. Gerber P, Anderin C, Gustafsson UO, Thorell A. Weight loss before gastric bypass and postoperative weight change: data from the Scandinavian Obesity Registry (SOReg) Surg Obes Relat Dis. 2016;12(3):556–562.
    1. Ross LJ, Wallin S, Osland EJ, Memon MA. Commercial very low energy meal replacements for preoperative weight loss in obese patients: a systematic review. Obes Surg. 2016;26(6):1343–1351.
    1. Hughes MJ, Hackney RJ, Lamb PJ, Wigmore SJ, Christopher Deans DA, Skipworth RJE. Prehabilitation before major abdominal surgery: a systematic review and meta-analysis. World J Surg. 2019;43(7):1661–1668.
    1. Valkenet K, van de Port IG, Dronkers JJ, de Vries WR, Lindeman E, Backx FJ. The effects of preoperative exercise therapy on postoperative outcome: a systematic review. Clin Rehabil. 2011;25(2):99–111.
    1. Marc-Hernández A, Ruiz-Tovar J, Aracil A, Guillén S, Moya-Ramón M. Impact of exercise on body composition and cardiometabolic risk factors in patients awaiting bariatric surgery. Obes Surg. 2019;29(12):3891–3900.
    1. Baillot A, Mampuya WM, Dionne IJ, Comeau E, Méziat-Burdin A, Langlois MF. Impacts of supervised exercise training in addition to interdisciplinary lifestyle management in subjects awaiting bariatric surgery: a randomized controlled study. Obes Surg. 2016;26(11):2602–2610.
    1. Lloréns J, Rovira L, Ballester M, et al. Preoperative inspiratory muscular training to prevent postoperative hypoxemia in morbidly obese patients undergoing laparoscopic bariatric surgery. A randomized clinical trial Obes Surg. 2015;25(6):1003–1009.
    1. McSorley ST, Roxburgh CSD, Horgan PG, McMillan DC. The impact of preoperative dexamethasone on the magnitude of the postoperative systemic inflammatory response and complications following surgery for colorectal cancer. Ann Surg Oncol. 2017;24(8):2104–2112.
    1. McSorley ST, Horgan PG, McMillan DC. The impact of preoperative corticosteroids on the systemic inflammatory response and postoperative complications following surgery for gastrointestinal cancer: a systematic review and meta-analysis. Crit Rev Oncol Hematol. 2016;101:139–150.
    1. Zhang T, Xu Y, Yao Y, et al. (2021) Randomized Controlled Trial: Perioperative Dexamethasone Reduces Excessive Postoperative Inflammatory Response and Ileus After Surgery for Inflammatory Bowel Disease. Inflamm Bowel Dis. Online ahead of print.
    1. Lex JR, Edwards TC, Packer TW, Jones GG, Ravi B. Perioperative systemic dexamethasone reduces length of stay in total joint arthroplasty: a systematic review and meta-analysis of randomized controlled trials. J Arthroplasty. 2021;36(3):1168–1186.
    1. Polderman JA, Farhang-Razi V, Van Dieren S, et al. Adverse side effects of dexamethasone in surgical patients. Cochrane Database Syst Rev. 2018;8(8):Cd011940.
    1. Srinivasa S, Kahokehr AA, Yu TC, Hill AG. Preoperative glucocorticoid use in major abdominal surgery: systematic review and meta-analysis of randomized trials. Ann Surg. 2011;254(2):183–191.
    1. Waldron NH, Jones CA, Gan TJ, Allen TK, Habib AS. Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and meta-analysis. Br J Anaesth. 2013;110(2):191–200.
    1. Singh PP, Srinivasa S, Lemanu DP, Maccormick AD, Hill AG. Statins in abdominal surgery: a systematic review. J Am Coll Surg. 2012;214(3):356–366.
    1. Komatsu R, Yilmaz HO, Makarova N, et al. Association between preoperative statin use and respiratory complications after noncardiac surgery: a retrospective cohort analysis. Anesth Analg. 2020;133(1):123–132.
    1. London MJ, Schwartz GG, Hur K, Henderson WG. Association of perioperative statin use with mortality and morbidity after major noncardiac surgery. JAMA Intern Med. 2017;177(2):231–242.
    1. Pourlotfi A, Ahl R, Sjolin G, et al. Statin therapy and postoperative short-term mortality after rectal cancer surgery. Colorectal Dis. 2021;23(4):875–881.
    1. Im C, Oh TK, Song IA, Jeon YT (2019) Preoperative Statin Use and 90-Day Mortality after Noncardiac Surgery: A Hospital Registry Study. Ann Surg. 2019. Online ahead of print
    1. Ma BX, Li H, Li JS, Wu SS. Effect of statins on preventing infectious complications after surgery: systematic review and meta-analysis. J Int Med Res. 2015;43(5):610–618.
    1. Berwanger O, Le Manach Y, Suzumura EA, et al. Association between pre-operative statin use and major cardiovascular complications among patients undergoing non-cardiac surgery: the VISION study. Eur Heart J. 2016;37(2):177–185.
    1. Singh PP, Lemanu DP, Soop M, Bissett IP, Harrison J, Hill AG. Perioperative simvastatin therapy in major colorectal surgery: a prospective, double-blind randomized controlled trial. J Am Coll Surg. 2016;223(2):308–320.e301.
    1. Berwanger O, de Barros ESPG, Barbosa RR, et al. Atorvastatin for high-risk statin-naïve patients undergoing noncardiac surgery: the Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose (LOAD) randomized trial. Am Heart J. 2017;184:88–96.
    1. Li H, Lin YL, Diao SL, Ma BX, Liu XL. Does short preoperative statin therapy prevent infectious complications in adults undergoing cardiac or non-cardiac surgery? A meta-analysis of 5 randomized placebo-controlled trials. Saudi Med J. 2016;37(5):492–497.
    1. Blessberger H, Lewis SR, Pritchard MW, et al. Perioperative beta-blockers for preventing surgery-related mortality and morbidity in adults undergoing non-cardiac surgery. Cochrane Database Syst Rev. 2019;9(9):Cd013438.
    1. Devereaux PJ, Yang H, Yusuf S, et al. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet. 2008;371(9627):1839–1847.
    1. Ahl R, Matthiessen P, Fang X, et al. Beta-blockade in rectal cancer surgery: a simple measure of improving outcomes. Ann Surg. 2020;271(1):140–146.
    1. Ahl R, Matthiessen P, Fang X, et al. Effect of beta-blocker therapy on early mortality after emergency colonic cancer surgery. Br J Surg. 2019;106(4):477–483.
    1. Stenberg E, Mohseni S, Cao Y, Naslund E. Limited effect of beta-blockade on postoperative outcome after laparoscopic gastric bypass surgery. Obes Surg. 2020;30(1):139–145.
    1. Jørgensen ME, Andersson C, Venkatesan S, Sanders RD. Beta-blockers in noncardiac surgery: did observational studies put us back on safe ground? Br J Anaesth. 2018;121(1):16–25.
    1. Harter RL, Kelly WB, Kramer MG, Perez CE, Dzwonczyk RR. A comparison of the volume and pH of gastric contents of obese and lean surgical patients. Anesth Analg. 1998;86(1):147–152.
    1. Juvin P, Fevre G, Merouche M, Vallot T, Desmonts JM. Gastric residue is not more copious in obese patients. Anesth Analg. 2001;93(6):1621–1622.
    1. Cardoso-Junior A, Coelho LG, Savassi-Rocha PR, et al. Gastric emptying of solids and semi-solids in morbidly obese and non-obese subjects: an assessment using the 13C-octanoic acid and 13C-acetic acid breath tests. Obes Surg. 2007;17(2):236–241.
    1. Buchholz V, Berkenstadt H, Goitein D, Dickman R, Bernstine H, Rubin M. Gastric emptying is not prolonged in obese patients. Surg Obes Relat Dis. 2013;9(5):714–717.
    1. Seimon RV, Brennan IM, Russo A, et al. Gastric emptying, mouth-to-cecum transit, and glycemic, insulin, incretin, and energy intake responses to a mixed-nutrient liquid in lean, overweight, and obese males. Am J Physiol Endocrinol Metab. 2013;304(3):E294–300.
    1. Maltby JR, Pytka S, Watson NC, Cowan RA, Fick GH. Drinking 300 mL of clear fluid two hours before surgery has no effect on gastric fluid volume and pH in fasting and non-fasting obese patients. Can J Anaesth. 2004;51(2):111–115.
    1. Maltby JR. Fasting from midnight–the history behind the dogma. Best Pract Res Clin Anaesthesiol. 2006;20(3):363–378.
    1. Ishihara H, Singh H, Giesecke AH. Relationship between diabetic autonomic neuropathy and gastric contents. Anesth Analg. 1994;78(5):943–947.
    1. Bertin E, Schneider N, Abdelli N, et al. Gastric emptying is accelerated in obese type 2 diabetic patients without autonomic neuropathy. Diabetes Metab. 2001;27(3):357–364.
    1. Ljungqvist O, Jonathan E. Rhoads lecture 2011: Insulin resistance and enhanced recovery after surgery. JPEN J Parenter Enteral Nutr. 2012;36(4):389–398.
    1. Awad S, Varadhan KK, Ljungqvist O, Lobo DN. A meta-analysis of randomised controlled trials on preoperative oral carbohydrate treatment in elective surgery. Clin Nutr. 2013;32(1):34–44.
    1. Smith MD, McCall J, Plank L, Herbison GP, Soop M, Nygren J. Preoperative carbohydrate treatment for enhancing recovery after elective surgery. Cochrane Database Syst Rev. 2014 doi: 10.1002/14651858.CD009161.pub2.
    1. Pimenta GP, Capellan DA, de Aguilar-Nascimento JE. Sleeve gastrectomy with or without a multimodal perioperative care. A Randomized Pilot Study Obes Surg. 2015;25(9):1639–1646.
    1. Gustafsson UO, Nygren J, Thorell A, et al. Pre-operative carbohydrate loading may be used in type 2 diabetes patients. Acta Anaesthesiol Scand. 2008;52(7):946–951.
    1. Azagury DE, Ris F, Pichard C, Volonte F, Karsegard L, Huber O. Does perioperative nutrition and oral carbohydrate load sustainably preserve muscle mass after bariatric surgery? A randomized control trial. Surg Obes Relat Dis. 2015;11(4):920–926.
    1. Albalawi Z, Laffin M, Gramlich L, Senior P, McAlister FA. Enhanced recovery after surgery (ERAS(®)) in Individuals with diabetes: a systematic review. World J Surg. 2017;41(8):1927–1934.
    1. Jones KL, Horowitz M, Wishart MJ, Maddox AF, Harding PE, Chatterton BE. Relationships between gastric emptying, intragastric meal distribution and blood glucose concentrations in diabetes mellitus. J Nucl Med. 1995;36(12):2220–2228.
    1. Lemanu DP, Singh PP, Berridge K, et al. Randomized clinical trial of enhanced recovery versus standard care after laparoscopic sleeve gastrectomy. Br J Surg. 2013;100(4):482–489.
    1. Ronellenfitsch U, Schwarzbach M, Kring A, Kienle P, Post S, Hasenberg T. The effect of clinical pathways for bariatric surgery on perioperative quality of care. Obes Surg. 2012;22(5):732–739.
    1. Karlsson A, Wendel K, Polits S, Gislason H, Hedenbro JL. Preoperative nutrition and postoperative discomfort in an ERAS setting: a randomized study in gastric bypass surgery. Obes Surg. 2016;26(4):743–748.
    1. Halliday TA, Sundqvist J, Hultin M, Walldén J. Post-operative nausea and vomiting in bariatric surgery patients: an observational study. Acta Anaesthesiol Scand. 2017;61(5):471–479.
    1. Groene P, Eisenlohr J, Zeuzem C, Dudok S, Karcz K, Hofmann-Kiefer K. Postoperative nausea and vomiting in bariatric surgery in comparison to non-bariatric gastric surgery. Wideochir Inne Tech Maloinwazyjne. 2019;14(1):90–95.
    1. Kushner BS, Freeman D, Sparkman J, Salles A, Eagon JC, Eckhouse SR. Assessment of postoperative nausea and vomiting after bariatric surgery using a validated questionnaire. Surg Obes Relat Dis. 2020;16(10):1505–1513.
    1. Gan TJ, Belani KG, Bergese S, et al. Fourth consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg. 2020;131(2):411–448.
    1. Ziemann-Gimmel P, Goldfarb AA, Koppman J, Marema RT. Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis. Br J Anaesth. 2014;112(5):906–911.
    1. Bamgbade OA, Oluwole O, Khaw RR. Perioperative antiemetic therapy for fast-track laparoscopic bariatric surgery. Obes Surg. 2018;28(5):1296–1301.
    1. Alpert MA. Obesity cardiomyopathy: pathophysiology and evolution of the clinical syndrome. Am J Med Sci. 2001;321(4):225–236.
    1. Mythen MG, Webb AR. Perioperative plasma volume expansion reduces the incidence of gut mucosal hypoperfusion during cardiac surgery. Arch Surg. 1995;130(4):423–429.
    1. Shoemaker WC, Montgomery ES, Kaplan E, Elwyn DH. Physiologic patterns in surviving and nonsurviving shock patients Use of sequential cardiorespiratory variables in defining criteria for therapeutic goals and early warning of death. Arch Surg. 1973;106(5):630–636.
    1. Shoemaker WC, Appel PL, Kram HB. Role of oxygen debt in the development of organ failure sepsis, and death in high-risk surgical patients. Chest. 1992;102(1):208–215.
    1. Myles PS, Bellomo R, Corcoran T, et al. Restrictive versus liberal fluid therapy for major abdominal surgery. N Engl J Med. 2018;378(24):2263–2274.
    1. Chen F, Rasouli MR, Ellis AR, et al. Associations between perioperative crystalloid volume and adverse outcomes in five surgical populations. J Surg Res. 2020;251:26–32.
    1. Major P, Wysocki M, Torbicz G, et al. Risk factors for prolonged length of hospital stay and readmissions after laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass. Obes Surg. 2018;28(2):323–332.
    1. Reiterer C, Kabon B, Zotti O, Obradovic M, Kurz A, Fleischmann E. Effect of goal-directed crystalloid- versus colloid-based fluid strategy on tissue oxygen tension: a randomised controlled trial. Br J Anaesth. 2019;123(6):768–776.
    1. Muhlbacher J, Luf F, Zotti O, Herkner H, Fleischmann E, Kabon B. Effect of intraoperative goal-directed fluid management on tissue oxygen tension in obese patients: a randomized controlled trial. Obes Surg. 2021;31(3):1129–1138.
    1. Munoz JL, Gabaldon T, Miranda E, et al. Goal-directed fluid therapy on laparoscopic sleeve gastrectomy in morbidly obese patients. Obes Surg. 2016;26(11):2648–2653.
    1. Myburgh JA, Mythen MG. Resuscitation fluids. N Engl J Med. 2013;369(13):1243–1251.
    1. Jacob M, Chappell D, Rehm M. Clinical update: perioperative fluid management. Lancet. 2007;369(9578):1984–1986.
    1. Hahn RG. Volume kinetics for infusion fluids. Anesthesiology. 2010;113(2):470–481.
    1. Kimberger O, Arnberger M, Brandt S, et al. Goal-directed colloid administration improves the microcirculation of healthy and perianastomotic colon. Anesthesiology. 2009;110(3):496–504.
    1. Rehm M, Zahler S, Lotsch M, et al. Endothelial glycocalyx as an additional barrier determining extravasation of 6% hydroxyethyl starch or 5% albumin solutions in the coronary vascular bed. Anesthesiology. 2004;100(5):1211–1223.
    1. Obradovic M, Kurz A, Kabon B, et al. The effect of intraoperative goal-directed crystalloid versus colloid administration on perioperative inflammatory markers - a substudy of a randomized controlled trial. BMC Anesthesiol. 2020;20(1):210.
    1. Kabon B, Sessler DI, Kurz A. Crystalloid-colloid study t effect of intraoperative goal-directed balanced crystalloid versus colloid administration on major postoperative morbidity: a randomized trial. Anesthesiology. 2019;130(5):728–744.
    1. Chowdhury AH, Cox EF, Francis ST, Lobo DN. A randomized, controlled, double-blind crossover study on the effects of 1-L infusions of 6% hydroxyethyl starch suspended in 0.9% saline (voluven) and a balanced solution (Plasma Volume Redibag) on blood volume, renal blood flow velocity, and renal cortical tissue perfusion in healthy volunteers. Ann Surg. 2014;259(5):881–887.
    1. Weinberg L, Li M, Churilov L, et al. Associations of fluid amount, type, and balance and acute kidney injury in patients undergoing major surgery. Anaesth Intensive Care. 2018;46(1):79–87.
    1. Pfortmueller CA, Funk GC, Reiterer C, et al. Normal saline versus a balanced crystalloid for goal-directed perioperative fluid therapy in major abdominal surgery: a double-blind randomised controlled study. Br J Anaesth. 2018;120(2):274–283.
    1. Ingrande J, Brodsky JB, Lemmens HJ. Lean body weight scalar for the anesthetic induction dose of propofol in morbidly obese subjects. Anesth Analg. 2011;113(1):57–62.
    1. Servin F, Farinotti R, Haberer JP, Desmonts JM. Propofol infusion for maintenance of anesthesia in morbidly obese patients receiving nitrous oxide. A clinical and pharmacokinetic study Anesthesiology. 1993;78(4):657–665.
    1. Cortínez LI, De la Fuente N, Eleveld DJ, et al. Performance of propofol target-controlled infusion models in the obese: pharmacokinetic and pharmacodynamic analysis. Anesth Analg. 2014;119(2):302–310.
    1. Lehavi A, Sandler O, Mahajna A, Weissman A, Katz YS. Comparison of rhabdomyolysis markers in patients undergoing bariatric surgery with propofol and inhalation-based anesthesia. Obes Surg. 2015;25(10):1923–1927.
    1. Singh PM, Borle A, McGavin J, Trikha A, Sinha A. Comparison of the recovery profile between desflurane and sevoflurane in patients undergoing bariatric surgery-a meta-analysis of randomized controlled trials. Obes Surg. 2017;27(11):3031–3039.
    1. Avidan MS, Jacobsohn E, Glick D, et al. Prevention of intraoperative awareness in a high-risk surgical population. N Engl J Med. 2011;365(7):591–600.
    1. Mashour GA, Shanks A, Tremper KK, et al. Prevention of intraoperative awareness with explicit recall in an unselected surgical population: a randomized comparative effectiveness trial. Anesthesiology. 2012;117(4):717–725.
    1. Oderda GM, Senagore AJ, Morland K, et al. Opioid-related respiratory and gastrointestinal adverse events in patients with acute postoperative pain: prevalence, predictors, and burden. J Pain Palliat Care Pharmacother. 2019;33(3–4):82–97.
    1. Brown EN, Pavone KJ, Naranjo M. Multimodal general anesthesia: theory and practice. Anesth Analg. 2018;127(5):1246–1258.
    1. Falcão LFRFA, Silva BD. Anestesia livre de opioides. In: Nunes RRBA, Duarte LTD, editors. PROANESTESIA Programa de Atualização em Anestesiologia. Porto Alegre: Artmed Panamericana; 2018. pp. 141–172.
    1. Mulier J. Opioid free general anesthesia: A paradigm shift? Rev Esp Anestesiol Reanim. 2017;64(8):427–430.
    1. Mulier JPDB. A prospective randomized controlled trial comparing a multitarget opioid free anaesthesia (OFA) and a 3-Liter volume calculated airseal carbon dioxide insufflator with a balanced anaesthesia using sufentanil-sevoflurane and a standard 15 MmHg carbon dioxide pressure pneumoperitoneum insufflator in a 2x2 factorial design. J Clin Anesth Pain Med. 2018;2(2):6.
    1. Govindarajan R, Ghosh B, Sathyamoorthy MK, et al. Efficacy of ketorolac in lieu of narcotics in the operative management of laparoscopic surgery for morbid obesity. Surg Obes Relat Dis. 2005;1(6):530–535.
    1. Beloeil H, Albaladejo P, Sion A, et al. Multicentre, prospective, double-blind, randomised controlled clinical trial comparing different non-opioid analgesic combinations with morphine for postoperative analgesia: the OCTOPUS study. Br J Anaesth. 2019;122(6):e98–e106.
    1. Foldi M, Soos A, Hegyi P, et al. Transversus abdominis plane block appears to be effective and safe as a part of multimodal analgesia in bariatric surgery: a meta-analysis and systematic review of randomized controlled trials. Obes Surg. 2021;31(2):531–543.
    1. Boerboom SL, de Haes A, Vd Wetering L, et al. Preperitoneal bupivacaine infiltration reduces postoperative opioid consumption, acute pain, and chronic postsurgical pain after bariatric surgery: a randomized controlled trial. Obes Surg. 2018;28(10):3102–3110.
    1. Omar I, Abualsel A. Efficacy of intraperitoneal instillation of bupivacaine after bariatric surgery: randomized controlled trial. Obes Surg. 2019;29(6):1735–1741.
    1. Chin KJ, Malhas L, Perlas A. The Erector spinae plane block provides visceral abdominal analgesia in bariatric surgery: a report of 3 Cases. Reg Anesth Pain Med. 2017;42(3):372–376.
    1. Collins JS, Lemmens HJ, Brodsky JB (2006) Obesity and difficult intubation: where is the evidence?. Anesthesiology, 104(3):617; author reply 618–619
    1. Moon TS, Fox PE, Somasundaram A, et al. The influence of morbid obesity on difficult intubation and difficult mask ventilation. J Anesth. 2019;33(1):96–102.
    1. Wong DT, Dallaire A, Singh KP, et al. High-flow nasal oxygen improves safe apnea time in morbidly obese patients undergoing general anesthesia: a randomized controlled trial. Anesth Analg. 2019;129(4):1130–1136.
    1. Fattahi T, Chafin C, Bunnell A. Tracheostomy in the morbidly obese: difficulties and challenges. J Oral Maxillofac Surg. 2017;75(7):1372–1375.
    1. Lewis SR, Butler AR, Parker J, Cook TM, Smith AF. Videolaryngoscopy versus direct laryngoscopy for adult patients requiring tracheal intubation. Cochrane Database Syst Rev. 2016;11(11):Cd011136.
    1. Pieters BMA, Maas EHA, Knape JTA, van Zundert AAJ. Videolaryngoscopy vs direct laryngoscopy use by experienced anaesthetists in patients with known difficult airways: a systematic review and meta-analysis. Anaesthesia. 2017;72(12):1532–1541.
    1. Downey AW, Duggan LV, Adam LJ. A systematic review of meta-analyses comparing direct laryngoscopy with videolaryngoscopy. Can J Anaesth. 2021;68(5):706–714.
    1. Cordes SR, Best AR, Hiatt KK. The impact of obesity on adult tracheostomy complication rate. Laryngoscope. 2015;125(1):105–110.
    1. Nightingale CE, Margarson MP, Shearer E, et al. Peri-operative management of the obese surgical patient 2015: association of Anaesthetists of Great Britain and Ireland Society for Obesity and Bariatric Anaesthesia. Anaesthesia. 2015;70(7):859–876.
    1. Writing Committee for the PCGotPVNftCTNotESoA, Bluth T, Serpa Neto A, Schultz MJ, Pelosi P, Gama de Abreu M 2019 Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial. JAMA, 321(23):2292–2305
    1. Young CC, Harris EM, Vacchiano C, et al. Lung-protective ventilation for the surgical patient: international expert panel-based consensus recommendations. Br J Anaesth. 2019;123(6):898–913.
    1. Villar J, Kacmarek RM, Hedenstierna G. From ventilator-induced lung injury to physician-induced lung injury: why the reluctance to use small tidal volumes? Acta Anaesthesiol Scand. 2004;48(3):267–271.
    1. Rackley CR, MacIntyre NR. Low tidal volumes for everyone? Chest. 2019;156(4):783–791.
    1. Borges JB, Amato MBP, Hedenstierna G. The increasing call for protective ventilation during anesthesia. JAMA Surg. 2017;152(9):893–894.
    1. Neto AS, Hemmes SN, Barbas CS, et al. Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data. Lancet Respir Med. 2016;4(4):272–280.
    1. Futier E, Constantin JM, Paugam-Burtz C, et al. A trial of intraoperative low-tidal-volume ventilation in abdominal surgery. N Engl J Med. 2013;369(5):428–437.
    1. Aldenkortt M, Lysakowski C, Elia N, Brochard L, Tramer MR. Ventilation strategies in obese patients undergoing surgery: a quantitative systematic review and meta-analysis. Br J Anaesth. 2012;109(4):493–502.
    1. Pelosi P, Ravagnan I, Giurati G, et al. Positive end-expiratory pressure improves respiratory function in obese but not in normal subjects during anesthesia and paralysis. Anesthesiology. 1999;91(5):1221–1231.
    1. Costa Souza GM, Santos GM, Zimpel SA, Melnik T. Intraoperative ventilation strategies for obese patients undergoing bariatric surgery: systematic review and meta-analysis. BMC Anesthesiol. 2020;20(1):36.
    1. Ball L, Hemmes SNT, Serpa Neto A, et al. Intraoperative ventilation settings and their associations with postoperative pulmonary complications in obese patients. Br J Anaesth. 2018;121(4):899–908.
    1. Pereira SM, Tucci MR, Morais CCA, et al. Individual Positive End-expiratory Pressure Settings Optimize Intraoperative Mechanical Ventilation and Reduce Postoperative Atelectasis. Anesthesiology. 2018;129(6):1070–1081.
    1. Amato MB, Meade MO, Slutsky AS, et al. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med. 2015;372(8):747–755.
    1. Ladha K, Vidal Melo MF, McLean DJ, et al. Intraoperative protective mechanical ventilation and risk of postoperative respiratory complications: hospital based registry study. BMJ. 2015;351:h3646.
    1. Ball L, Pelosi P. How I ventilate an obese patient. Crit Care. 2019;23(1):176.
    1. Cadi P, Guenoun T, Journois D, Chevallier JM, Diehl JL, Safran D. Pressure-controlled ventilation improves oxygenation during laparoscopic obesity surgery compared with volume-controlled ventilation. Br J Anaesth. 2008;100(5):709–716.
    1. Fernandez-Bustamante A, Hashimoto S, Serpa Neto A, Moine P, Vidal Melo MF, Repine JE. Perioperative lung protective ventilation in obese patients. BMC Anesthesiol. 2015;15:56.
    1. Bagchi A, Rudolph MI, Ng PY, et al. The association of postoperative pulmonary complications in 109,360 patients with pressure-controlled or volume-controlled ventilation. Anaesthesia. 2017;72(11):1334–1343.
    1. Martini CH, Boon M, Bevers RF, Aarts LP, Dahan A. Evaluation of surgical conditions during laparoscopic surgery in patients with moderate vs deep neuromuscular block. Br J Anaesth. 2014;112(3):498–505.
    1. Staehr-Rye AK, Rasmussen LS, Rosenberg J, et al. Surgical space conditions during low-pressure laparoscopic cholecystectomy with deep versus moderate neuromuscular blockade: a randomized clinical study. Anesth Analg. 2014;119(5):1084–1092.
    1. Barrio J, Errando CL, García-Ramón J, Sellés R, San Miguel G, Gallego J. Influence of depth of neuromuscular blockade on surgical conditions during low-pressure pneumoperitoneum laparoscopic cholecystectomy: a randomized blinded study. J Clin Anesth. 2017;42:26–30.
    1. Kopman AF, Naguib M. Laparoscopic surgery and muscle relaxants: is deep block helpful? Anesth Analg. 2015;120(1):51–58.
    1. Özdemir-van Brunschot DMD, Braat AE, van der Jagt MFP, et al. Deep neuromuscular blockade improves surgical conditions during low-pressure pneumoperitoneum laparoscopic donor nephrectomy. Surg Endosc. 2018;32(1):245–251.
    1. Torensma B, Martini CH, Boon M, et al. Deep neuromuscular block improves surgical conditions during bariatric surgery and reduces postoperative pain: a randomized double blind controlled trial. PLoS ONE. 2016;11(12):e0167907.
    1. Fuchs-Buder T, Schmartz D, Baumann C, et al. Deep neuromuscular blockade improves surgical conditions during gastric bypass surgery for morbid obesity: a randomised controlled trial. Eur J Anaesthesiol. 2019;36(7):486–493.
    1. Mulier JP, Dillemans B. Anaesthetic factors affecting outcome after bariatric surgery, a retrospective levelled regression analysis. Obes Surg. 2019;29(6):1841–1850.
    1. Batistaki C, Tentes P, Deligiannidi P, Karakosta A, Florou P, Kostopanagiotou G. Residual neuromuscular blockade in a real life clinical setting: correlation with sugammadex or neostigmine administration. Minerva Anestesiol. 2016;82(5):550–558.
    1. Fortier LP, McKeen D, Turner K, et al. The RECITE study: a canadian prospective, multicenter study of the incidence and severity of residual neuromuscular blockade. Anesth Analg. 2015;121(2):366–372.
    1. Schreiber JU. Management of neuromuscular blockade in ambulatory patients. Curr Opin Anaesthesiol. 2014;27(6):583–588.
    1. Reinius H, Jonsson L, Gustafsson S, et al. Prevention of atelectasis in morbidly obese patients during general anesthesia and paralysis: a computerized tomography study. Anesthesiology. 2009;111(5):979–987.
    1. Murphy GS, Brull SJ. Residual neuromuscular block: lessons unlearned Part I: definitions, incidence, and adverse physiologic effects of residual neuromuscular block. Anesth Analg. 2010;111(1):120–128.
    1. Stewart PA, Liang SS, Li QS, et al. The impact of residual neuromuscular blockade, oversedation, and hypothermia on adverse respiratory events in a postanesthetic care unit: a prospective study of prevalence, predictors, and outcomes. Anesth Analg. 2016;123(4):859–868.
    1. Butterly A, Bittner EA, George E, Sandberg WS, Eikermann M, Schmidt U. Postoperative residual curarization from intermediate-acting neuromuscular blocking agents delays recovery room discharge. Br J Anaesth. 2010;105(3):304–309.
    1. Sauer M, Stahn A, Soltesz S, Noeldge-Schomburg G, Mencke T. The influence of residual neuromuscular block on the incidence of critical respiratory events. A randomised, prospective, placebo-controlled trial. Eur J Anaesthesiol. 2011;28(12):842–848.
    1. Hristovska AM, Duch P, Allingstrup M, Afshari A. The comparative efficacy and safety of sugammadex and neostigmine in reversing neuromuscular blockade in adults. A Cochrane systematic review with meta-analysis and trial sequential analysis. Anaesthesia. 2018;73(5):631–641.
    1. De Robertis E, Zito Marinosci G, Romano GM, et al. The use of sugammadex for bariatric surgery: analysis of recovery time from neuromuscular blockade and possible economic impact. Clinicoecon Outcomes Res. 2016;8:317–322.
    1. Kheterpal S, Vaughn MT, Dubovoy TZ, et al. Sugammadex versus neostigmine for reversal of neuromuscular blockade and postoperative pulmonary complications (STRONGER): a multicenter matched cohort analysis. Anesthesiology. 2020;132(6):1371–1381.
    1. Loupec T, Frasca D, Rousseau N, Faure JP, Mimoz O, Debaene B. Appropriate dosing of sugammadex to reverse deep rocuronium-induced neuromuscular blockade in morbidly obese patients. Anaesthesia. 2016;71(3):265–272.
    1. Li D, Wang Y, Zhou Y, Yin C. Efficacy and safety of sugammadex doses calculated on the basis of corrected body weight and total body weight for the reversal of deep neuromuscular blockade in morbidly obese patients. J Int Med Res. 2021;49(1):300060520985679.
    1. Badaoui R, Cabaret A, Alami Y, et al. Reversal of neuromuscular blockade by sugammadex in laparoscopic bariatric surgery: in support of dose reduction. Anaesth Crit Care Pain Med. 2016;35(1):25–29.
    1. de Kam PJ, Nolte H, Good S, et al. Sugammadex hypersensitivity and underlying mechanisms: a randomised study of healthy non-anaesthetised volunteers. Br J Anaesth. 2018;121(4):758–767.
    1. Min KC, Bondiskey P, Schulz V, et al. Hypersensitivity incidence after sugammadex administration in healthy subjects: a randomised controlled trial. Br J Anaesth. 2018;121(4):749–757.
    1. Lujan JA, Frutos MD, Hernandez Q, et al. Laparoscopic versus open gastric bypass in the treatment of morbid obesity: a randomized prospective study. Ann Surg. 2004;239(4):433–437.
    1. Nguyen NT, Goldman C, Rosenquist CJ, et al. Laparoscopic versus open gastric bypass: a randomized study of outcomes, quality of life, and costs. Ann Surg. 2001;234(3):279–289.
    1. Westling A, Gustavsson S. Laparoscopic vs open Roux-en-Y gastric bypass: a prospective, randomized trial. Obes Surg. 2001;11(3):284–292.
    1. Buchwald H, Estok R, Fahrbach K, Banel D, Sledge I. Trends in mortality in bariatric surgery: a systematic review and meta-analysis. Surgery. 2007;142(4):621–632.
    1. Angrisani L, Santonicola A, Iovino P, et al. IFSO Worldwide survey 2016: primary, endoluminal, and revisional procedures. Obes Surg. 2018;28(12):3783–3794.
    1. Zhou J, Du R, Wang L, et al. The application of enhanced recovery after surgery (ERAS) for patients undergoing bariatric surgery: a systematic review and meta-analysis. Obes Surg. 2021;31(3):1321–1331.
    1. Aktimur R, Kirkil C, Yildirim K, Kutluer N. Enhanced recovery after surgery (ERAS) in one-anastomosis gastric bypass surgery: a matched-cohort study. Surg Obes Relat Dis. 2018;14(12):1850–1856.
    1. Blanchet MC, Gignoux B, Matussiere Y, et al. Experience with an enhanced recovery after surgery (ERAS) program for bariatric surgery: comparison of MGB and LSG in 374 patients. Obes Surg. 2017;27(7):1896–1900.
    1. Hahl T, Peromaa-Haavisto P, Tarkiainen P, Knutar O, Victorzon M. OutCOME OF LAPAROSCOPIC GASTRIC BYPAss (LRYGB) with a program for enhanced recovery after surgery (ERAS) Obes Surg. 2016;26(3):505–511.
    1. Gero D, Raptis DA, Vleeschouwers W, et al. Defining global benchmarks in bariatric surgery: a retrospective multicenter analysis of minimally invasive roux-en-y gastric bypass and sleeve gastrectomy. Ann Surg. 2019;270(5):859–867.
    1. Zevin B, Aggarwal R, Grantcharov TP. Volume-outcome association in bariatric surgery: a systematic review. Ann Surg. 2012;256(1):60–71.
    1. Stenberg E, Szabo E, Agren G, et al. Early complications after laparoscopic gastric bypass surgery: results from the scandinavian obesity surgery registry. Ann Surg. 2014;260(6):1040–1047.
    1. El-Kadre L, Tinoco AC, Tinoco RC, Aguiar L, Santos T. Overcoming the learning curve of laparoscopic Roux-en-Y gastric bypass: a 12-year experience. Surg Obes Relat Dis. 2013;9(6):867–872.
    1. Bonrath EM, Dedy NJ, Gordon LE, Grantcharov TP. Comprehensive surgical coaching enhances surgical skill in the operating room: a randomized controlled trial. Ann Surg. 2015;262(2):205–212.
    1. Breaux JA, Kennedy CI, Richardson WS. Advanced laparoscopic skills decrease the learning curve for laparoscopic Roux-en-Y gastric bypass. Surg Endosc. 2007;21(6):985–988.
    1. Wolter S, Duprée A, ElGammal A, et al. Mentorship programs in bariatric surgery reduce perioperative complication rate at equal short-term outcome-results from the OPTIMIZE trial. Obes Surg. 2019;29(1):127–136.
    1. Pournaras DJ, Jafferbhoy S, Titcomb DR, et al. Three hundred laparoscopic Roux-en-Y gastric bypasses: managing the learning curve in higher risk patients. Obes Surg. 2010;20(3):290–294.
    1. Sánchez-Santos R, Estévez S, Tomé C, et al. Training programs influence in the learning curve of laparoscopic gastric bypass for morbid obesity: a systematic review. Obes Surg. 2012;22(1):34–41.
    1. van Rijswijk AS, Moes DE, Geubbels N, et al. Can a laparoscopic Roux-en-Y gastric bypass be safely performed by surgical residents in a bariatric center-of-excellence? The learning curve of surgical residents in bariatric surgery. Surg Endosc. 2018;32(2):1012–1020.
    1. Liscia G, Scaringi S, Facchiano E, Quartararo G, Lucchese M. The role of drainage after Roux-en-Y gastric bypass for morbid obesity: a systematic review. Surg Obes Relat Dis. 2014;10(1):171–176.
    1. Doumouras AG, Maeda A, Jackson TD. The role of routine abdominal drainage after bariatric surgery: a metabolic and bariatric surgery accreditation and quality improvement program study. Surg Obes Relat Dis. 2017;13(12):1997–2003.
    1. Peña ME, Schlottmann F, Laxague F, Sadava EE, Buxhoeveden R. Usefulness of abdominal drain in laparoscopic roux-en-y gastric bypass: a randomized controlled trial. J Laparoendosc Adv Surg Tech A. 2020;30(5):538–541.
    1. Gundogan E, Kayaalp C, Aktas A, et al. Influence of drain placement on postoperative pain following laparoscopic Roux-en-Y gastric bypass for morbid obesity: randomized controlled trial. Obes Surg. 2018;28(11):3499–3504.
    1. Huerta S, Arteaga JR, Sawicki MP, Liu CD, Livingston EH. Assessment of routine elimination of postoperative nasogastric decompression after Roux-en-Y gastric bypass. Surgery. 2002;132(5):844–848.
    1. Rossetti G, Fei L, Docimo L, et al. Is nasogastric decompression useful in prevention of leaks after laparoscopic sleeve gastrectomy? A randomized trial J Invest Surg. 2014;27(4):234–239.
    1. Robinson PD. Obesity and its impact on the respiratory system. Paediatr Respir Rev. 2014;15(3):219–226.
    1. Eichenberger A, Proietti S, Wicky S, et al. Morbid obesity and postoperative pulmonary atelectasis: an underestimated problem. Anesth Analg. 2002;95(6):1788–1792.
    1. Ahlin S, Manco M, Panunzi S, et al. A new sensitive and accurate model to predict moderate to severe obstructive sleep apnea in patients with obesity. Medicine (Baltimore) 2019;98(32):e16687.
    1. He J, Kryger MH, Zorick FJ, Conway W, Roth T. Mortality and apnea index in obstructive sleep apnea. Experience in 385 male patients. Chest. 1988;94(1):9–14.
    1. Chung F, Yang Y, Liao P. Predictive performance of the STOP-Bang score for identifying obstructive sleep apnea in obese patients. Obes Surg. 2013;23(12):2050–2057.
    1. Kaw R, Bhateja P, Paz YMH, et al. Postoperative complications in patients with unrecognized obesity hypoventilation syndrome undergoing elective noncardiac surgery. Chest. 2016;149(1):84–91.
    1. de Raaff CA, Coblijn UK, de Vries N, van Wagensveld BA. Is fear for postoperative cardiopulmonary complications after bariatric surgery in patients with obstructive sleep apnea justified? A systematic review Am J Surg. 2016;211(4):793–801.
    1. Bolden N, Posner KL, Domino KB, et al. Postoperative critical events associated with obstructive sleep Apnea: results from the society of anesthesia and sleep medicine obstructive sleep apnea registry. Anesth Analg. 2020;131(4):1032–1041.
    1. Mehta V, Vasu TS, Phillips B, Chung F. Obstructive sleep apnea and oxygen therapy: a systematic review of the literature and meta-analysis. J Clin Sleep Med. 2013;9(3):271–279.
    1. Young LR, Taxin ZH, Norman RG, Walsleben JA, Rapoport DM, Ayappa I. Response to CPAP withdrawal in patients with mild versus severe obstructive sleep apnea/hypopnea syndrome. Sleep. 2013;36(3):405–412.
    1. Nagappa M, Mokhlesi B, Wong J, Wong DT, Kaw R, Chung F. The effects of continuous positive airway pressure on postoperative outcomes in obstructive sleep apnea patients undergoing surgery: a systematic review and meta-analysis. Anesth Analg. 2015;120(5):1013–1023.
    1. Kohler M, Stoewhas AC, Ayers L, et al. Effects of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea: a randomized controlled trial. Am J Respir Crit Care Med. 2011;184(10):1192–1199.
    1. Practice guidelines for the perioperative management of patients with obstructive sleep apnea: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Management of patients with obstructive sleep apnea. Anesthesiology. 2014;120(2):268–286.
    1. Daigle CR, Brethauer SA, Tu C, et al. Which postoperative complications matter most after bariatric surgery? Prioritizing quality improvement efforts to improve national outcomes. Surg Obes Relat Dis. 2018;14(5):652–657.
    1. Samama MM. An epidemiologic study of risk factors for deep vein thrombosis in medical outpatients: the Sirius study. Arch Intern Med. 2000;160(22):3415–3420.
    1. Moulin PA, Dutour A, Ancel P, et al. Perioperative thromboprophylaxis in severely obese patients undergoing bariatric surgery: insights from a French national survey. Surg Obes Relat Dis. 2017;13(2):320–326.
    1. Clark LN, Helm MC, Gould JC. Practice patterns regarding post-discharge chemoprophylaxis for venous thromboembolism following bariatric surgery in the United States. Surg Obes Relat Dis. 2019;15(5):703–707.
    1. Brotman DJ, Shihab HM, Prakasa KR, et al. Pharmacologic and mechanical strategies for preventing venous thromboembolism after bariatric surgery: a systematic review and meta-analysis. JAMA Surg. 2013;148(7):675–686.
    1. Kakkos SK, Caprini JA, Geroulakos G, et al. Combined intermittent pneumatic leg compression and pharmacological prophylaxis for prevention of venous thromboembolism. Cochrane Database Syst Rev. 2016;9(9):Cd005258.
    1. Sachdeva A, Dalton M, Lees T. Graduated compression stockings for prevention of deep vein thrombosis. Cochrane Database Syst Rev. 2018;11(11):Cd001484.
    1. Abildgaard A, Madsen SA, Hvas AM. Dosage of anticoagulants in obesity: recommendations based on a systematic review. Semin Thromb Hemost. 2020;46(8):932–969.
    1. Karas LA, Nor Hanipah Z, Cetin D, et al. Assessment of empiric body mass index-based thromboprophylactic dosing of enoxaparin after bariatric surgery: evidence for dosage adjustment using anti-factor Xa in high-risk patients. Surg Obes Relat Dis. 2021;17(1):153–160.
    1. Stier C, Koschker AC, Stier R, Sosnierz A, Chiappetta S. Are we missing treatment standards for thromboprophylaxis of the obese and super-obese patient population? A prospective systematic cohort study. Obes Surg. 2020;30(5):1704–1711.
    1. Aminian A, Andalib A, Khorgami Z, et al. Who should get extended thromboprophylaxis after bariatric surgery?: a risk assessment tool to guide indications for post-discharge pharmacoprophylaxis. Ann Surg. 2017;265(1):143–150.
    1. Mossberg KE, Pournaras DJ, Welbourn R, le Roux CW, Brogren H. Differential response of plasma plasminogen activator inhibitor 1 after weight loss surgery in patients with or without type 2 diabetes. Surg Obes Relat Dis. 2017;13(1):53–57.
    1. Bergqvist D, Agnelli G, Cohen AT, et al. Duration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancer. N Engl J Med. 2002;346(13):975–980.
    1. Hull RD, Pineo GF, Stein PD, et al. Extended out-of-hospital low-molecular-weight heparin prophylaxis against deep venous thrombosis in patients after elective hip arthroplasty: a systematic review. Ann Intern Med. 2001;135(10):858–869.
    1. Rowland SP, Dharmarajah B, Moore HM, et al. Inferior vena cava filters for prevention of venous thromboembolism in obese patients undergoing bariatric surgery: a systematic review. Ann Surg. 2015;261(1):35–45.
    1. Shoar S, Saber AA, Rubenstein R, et al. Portomesentric and splenic vein thrombosis (PMSVT) after bariatric surgery: a systematic review of 110 patients. Surg Obes Relat Dis. 2018;14(1):47–59.
    1. Shaheen O, Siejka J, Thatigotla B, Pham DT. A systematic review of portomesenteric vein thrombosis after sleeve gastrectomy. Surg Obes Relat Dis. 2017;13(8):1422–1431.
    1. Parrott J, Frank L, Rabena R, Craggs-Dino L, Isom KA, Greiman L. American society for metabolic and bariatric surgery integrated health nutritional guidelines for the surgical weight loss patient 2016 update: micronutrients. Surg Obes Relat Dis. 2017;13(5):727–741.
    1. Parrott JM, Craggs-Dino L, Faria SL, O'Kane M. The optimal nutritional programme for bariatric and metabolic surgery. Curr Obes Rep. 2020;9(3):326–338.
    1. O'Kane M. Nutritional consequences of bariatric surgery - prevention, detection and management. Curr Opin Gastroenterol. 2021;37(2):135–144.
    1. O'Kane M, Parretti HM, Pinkney J, et al. British obesity and metabolic surgery society guidelines on perioperative and postoperative biochemical monitoring and micronutrient replacement for patients undergoing bariatric surgery-2020 update. Obes Rev. 2020;21(11):e13087.
    1. Di Lorenzo N, Antoniou SA, Batterham RL, et al. Clinical practice guidelines of the european association for endoscopic surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC. EASO and ESPCOP Surg Endosc. 2020;34(6):2332–2358.
    1. Sherf-Dagan S, Sinai T, Goldenshluger A, et al. Nutritional assessment and preparation for adult bariatric surgery candidates: clinical practice. Adv Nutr. 2021;12(3):1020–1031.
    1. Sherf Dagan S, Goldenshluger A, Globus I, et al. Nutritional recommendations for adult bariatric surgery patients: clinical practice. Adv Nutr. 2017;8(2):382–394.
    1. Shoar S, Poliakin L, Rubenstein R, Saber AA. Single anastomosis duodeno-ileal switch (SADIS): a systematic review of efficacy and safety. Obes Surg. 2018;28(1):104–113.
    1. Homan J, Betzel B, Aarts EO, et al. Vitamin and mineral deficiencies after biliopancreatic diversion and biliopancreatic diversion with duodenal switch–the rule rather than the exception. Obes Surg. 2015;25(9):1626–1632.
    1. Coblijn UK, Goucham AB, Lagarde SM, Kuiken SD, van Wagensveld BA. Development of ulcer disease after Roux-en-Y gastric bypass, incidence, risk factors, and patient presentation: a systematic review. Obes Surg. 2014;24(2):299–309.
    1. Ying VW, Kim SH, Khan KJ, et al. Prophylactic PPI help reduce marginal ulcers after gastric bypass surgery: a systematic review and meta-analysis of cohort studies. Surg Endosc. 2015;29(5):1018–1023.
    1. Kang X, Zurita-Macias L, Hong D, Cadeddu M, Anvari M, Gmora S. A comparison of 30-day versus 90-day proton pump inhibitor therapy in prevention of marginal ulcers after laparoscopic Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2016;12(5):1003–1007.
    1. Wennerlund J, Gunnarsson U, Strigård K, Sundbom M. Acid-related complications after laparoscopic Roux-en-Y gastric bypass: risk factors and impact of proton pump inhibitors. Surg Obes Relat Dis. 2020;16(5):620–625.
    1. Collares-Pelizaro RVA, Santos JS, Nonino CB, dos Reis Dias LA, Gaitani CM, Salgado W., Jr Omeprazole absorption and fasting gastrinemia after Roux-en-Y gastric bypass. Obes Surg. 2017;27(9):2303–2307.
    1. Schulman AR, Chan WW, Devery A, Ryan MB, Thompson CC. Opened Proton Pump Inhibitor Capsules Reduce Time to Healing Compared With Intact Capsules for Marginal Ulceration Following Roux-en-Y Gastric Bypass. Clin Gastroenterol Hepatol. 2017;15(4):494–500.e491.
    1. Mandeville Y, Van Looveren R, Vancoillie PJ, et al. Moderating the enthusiasm of sleeve gastrectomy: up to fifty percent of reflux symptoms after ten years in a consecutive series of one hundred laparoscopic sleeve gastrectomies. Obes Surg. 2017;27(7):1797–1803.
    1. Kraljević M, Cordasco V, Schneider R, et al. Long-term effects of laparoscopic sleeve gastrectomy: what are the results beyond 10 years? Obes Surg. 2021;31(8):3427–3433.
    1. Braghetto I, Korn O. Late esophagogastric anatomic and functional changes after sleeve gastrectomy and its clinical consequences with regards to gastroesophageal reflux disease. Dis Esophagus. 2019;32(6):doz020.
    1. Sebastianelli L, Benois M, Vanbiervliet G, et al. Systematic endoscopy 5 years after sleeve gastrectomy results in a high rate of barrett's esophagus: results of a multicenter study. Obes Surg. 2019;29(5):1462–1469.
    1. Adams LB, Chang C, Pope J, Kim Y, Liu P, Yates A. Randomized, prospective comparison of ursodeoxycholic acid for the prevention of gallstones after sleeve gastrectomy. Obes Surg. 2016;26(5):990–994.
    1. Sakran N, Dar R, Assalia A, et al. The use of ursolit for gallstone prophylaxis following bariatric surgery: a randomized-controlled trial. Updates Surg. 2020;72(4):1125–1133.
    1. Miller K, Hell E, Lang B, Lengauer E. Gallstone formation prophylaxis after gastric restrictive procedures for weight loss: a randomized double-blind placebo-controlled trial. Ann Surg. 2003;238(5):697–702.
    1. Wudel LJ, Jr, Wright JK, Debelak JP, Allos TM, Shyr Y, Chapman WC. Prevention of gallstone formation in morbidly obese patients undergoing rapid weight loss: results of a randomized controlled pilot study. J Surg Res. 2002;102(1):50–56.
    1. Sugerman HJ, Brewer WH, Shiffman ML, et al. A multicenter, placebo-controlled, randomized, double-blind, prospective trial of prophylactic ursodiol for the prevention of gallstone formation following gastric-bypass-induced rapid weight loss. Am J Surg. 1995;169(1):91–96.
    1. Magouliotis DE, Tasiopoulou VS, Svokos AA, et al. Ursodeoxycholic acid in the prevention of gallstone formation after bariatric surgery: an updated systematic review and meta-analysis. Obes Surg. 2017;27(11):3021–3030.
    1. Boerlage TCC, Haal S, Maurits de Brauw L, et al. Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery: study protocol for a randomized controlled trial (UPGRADE trial) BMC Gastroenterol. 2017;17(1):164.
    1. Leyva-Alvizo A, Arredondo-Saldaña G, Leal-Isla-Flores V, et al. Systematic review of management of gallbladder disease in patients undergoing minimally invasive bariatric surgery. Surg Obes Relat Dis. 2020;16(1):158–164.
    1. Wanjura V, Szabo E, Osterberg J, Ottosson J, Enochsson L, Sandblom G. Morbidity of cholecystectomy and gastric bypass in a national database. Br J Surg. 2018;105(1):121–127.
    1. Pournaras DJ, Aasheim ET, Bueter M, et al. Effect of bypassing the proximal gut on gut hormones involved with glycemic control and weight loss. Surg Obes Relat Dis. 2012;8(4):371–374.
    1. Poelemeijer YQM, Liem RSL, Vage V, et al. Gastric bypass versus sleeve gastrectomy: patient selection and short-term outcome of 47,101 primary operations from the Swedish, Norwegian, and Dutch national quality registries. Ann Surg. 2020;272(2):325–333.
    1. Frisch A, Chandra P, Smiley D, et al. Prevalence and clinical outcome of hyperglycemia in the perioperative period in noncardiac surgery. Diabetes Care. 2010;33(8):1783–1788.
    1. Kwon S, Thompson R, Dellinger P, Yanez D, Farrohki E, Flum D. Importance of perioperative glycemic control in general surgery: a report from the Surgical Care and Outcomes Assessment Program. Ann Surg. 2013;257(1):8–14.
    1. King JT, Jr, Goulet JL, Perkal MF, Rosenthal RA. Glycemic control and infections in patients with diabetes undergoing noncardiac surgery. Ann Surg. 2011;253(1):158–165.
    1. Pournaras DJ, Osborne A, Hawkins SC, et al. Remission of type 2 diabetes after gastric bypass and banding: mechanisms and 2 year outcomes. Ann Surg. 2010;252(6):966–971.
    1. Fenske WK, Pournaras DJ, Aasheim ET, et al. Can a protocol for glycaemic control improve type 2 diabetes outcomes after gastric bypass? Obes Surg. 2012;22(1):90–96.
    1. Thorell A, Hagström-Toft E. Treatment of diabetes prior to and after bariatric surgery. J Diabetes Sci Technol. 2012;6(5):1226–1232.
    1. Pournaras DJ, Hardwick RH, le Roux CW. Gastrointestinal surgery for obesity and cancer: 2 sides of the same coin. Surg Obes Relat Dis. 2017;13(4):720–721.
    1. Fearon KC, Ljungqvist O, Von Meyenfeldt M, et al. Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr. 2005;24(3):466–477.
    1. Tian YL, Cao SG, Liu XD, et al. Short- and long-term outcomes associated with enhanced recovery after surgery protocol vs conventional management in patients undergoing laparoscopic gastrectomy. World J Gastroenterol. 2020;26(37):5646–5660.
    1. Gustafsson UO, Scott MJ, Hubner M, et al. Guidelines for perioperative care in elective colorectal surgery: enhanced recovery after surgery (ERAS(®)) society recommendations: 2018. World J Surg. 2019;43(3):659–695.

Source: PubMed

3
Abonnere