Prevalence of and factors associated with low Back pain, thoracic spine pain and neck pain in Bashkortostan, Russia: the Ural Eye and Medical Study

Mukharram M Bikbov, Gyulli M Kazakbaeva, Rinat M Zainullin, Venera F Salavatova, Timur R Gilmanshin, Inga I Arslangareeva, Nikolai A Nikitin, Svetlana R Mukhamadieva, Dilya F Yakupova, Songhomitra Panda-Jonas, Renat I Khikmatullin, Said K Aminev, Ildar F Nuriev, Artur F Zaynetdinov, Yulia V Uzianbaeva, Jost B Jonas, Mukharram M Bikbov, Gyulli M Kazakbaeva, Rinat M Zainullin, Venera F Salavatova, Timur R Gilmanshin, Inga I Arslangareeva, Nikolai A Nikitin, Svetlana R Mukhamadieva, Dilya F Yakupova, Songhomitra Panda-Jonas, Renat I Khikmatullin, Said K Aminev, Ildar F Nuriev, Artur F Zaynetdinov, Yulia V Uzianbaeva, Jost B Jonas

Abstract

Background: Back pain and neck pain are leading causes of the burden of disease worldwide, while information about their prevalence in Russia is missing.

Methods: The population-based Ural Eye and Medical Study was conducted in a rural and urban region in Bashkortostan/Russia. As part of a detailed systematic examination, we assessed the prevalence of low back pain, thoracic spine pain and neck pain in an interview with standardized questions in 5397 study participants (mean age:58.6 ± 10.6 years;range:40-94 years).

Results: The mean prevalence of low back pain, thoracic spine pain and neck pain was 2912/5397 (54.0%;95% confidence interval (CI):52.6,55.3), 1271/5397 (23.6%;95%CI:22.4,24.7), and 1570/5397 (29.1%;95%CI:27.9,30.3), respectively. A higher prevalence of low back pain was associated with females (P = 0.04;odds ratio (OR):1.14;95%CI:1.004,1.30), younger age (P < 0.001;OR:0.99;95%CI:0.98,0.99), higher body mass index (P = 0.002;OR:1.02;95%CI:1.01,1.03), lower frequency of vigorous activities during leisure time (P = 0.001;OR:0.79;95%CI:0.69,0.90), more time spent sitting and reclining (P = 0.03;OR:1.00;95%CI:1.00,1.00), higher serum concentration of high-density lipoproteins (P = 0.004;OR:1.10;95%CI:1.03,1.18), higher prothrombin index (P = 0.003;OR:1.01;95%CI:1.003,1.01), higher prevalence of a history of cardiovascular disease (P = 0.004;OR:1.23;95%CI:1.07,1.42), falls (P < 0.004;OR:1.71;95%CI:1.45,2.00), bone fractures (P = 0.01;OR:1.18;95% CI:1.03,1.34), unconsciousness (P < 0.001;OR:1.78;95%CI:1.40,2.25), osteoarthritis (P < 0.001;OR:2.76;95%CI:2.34,3.26), iron-deficiency anemia (P < 0.001;OR:1.87;95%CI:1.41,2.50), and thyroid disorder (P = 0.004;OR:1.37;95%CI:1.10,1.70), fewer days of vegetable intake (P < 0.001;OR:0.89;95%CI:0.85,0.93), smaller amounts of salt intake (P = 0.008;OR:0.97;95%CI:0.94,0.99), higher anxiety score (P < 0.001;OR:1.05;95%CI:1.03,1.06), and in women, history of menopause (P = 0.02;OR:1.36;95%CI:1.05,1.75). The prevalence of thoracic spine pain and neck pain showed similar associations.

Conclusions: In a Russian population, the prevalence of low back pain, thoracic spine pain and neck pain (54.0, 23.6 and 29.1%, respectively) were correlated with parameters such as the female sex, younger age, higher body mass index, higher anxiety score, higher prevalence of a history of cardiovascular disease, lower frequency of vigorous activities and more time spent sitting or reclining. These data may be of interest for assessing the burden of back and neck pain in Russia as part of the global burden of disease.

Keywords: Back pain; Neck pain; Population-based study; Ural eye and medical study.

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Graph showing the prevalence of low back pain stratified by age in the Ural Eye and Medical Study
Fig. 2
Fig. 2
Graph showing the prevalence of thoracic spine pain stratified by age in the Ural Eye and Medical Study
Fig. 3
Fig. 3
Graph showing the prevalence of neck pain stratified by age in the Ural Eye and Medical Study

References

    1. GBD 2016 DALYs and HALE Collaborators Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390:1260–1344. doi: 10.1016/S0140-6736(17)32130-X.
    1. Hoy D, Bain C, Williams G, March L, Brooks P, Blyth F, Woolf A, Vos T, Buchbinder R. A systematic review of the global prevalence of low back pain. Arthritis Rheum. 2012;64:2028–2037. doi: 10.1002/art.34347.
    1. Johansson MS, Jensen Stochkendahl M, Hartvigsen J, Boyle E, Cassidy JD. Incidence and prognosis of mid-back pain in the general population: a systematic review. Eur J Pain. 2017;21:20–28. doi: 10.1002/ejp.884.
    1. Leboeuf-Yde C, Lauritsen JM. The prevalence of low back pain in the literature. A structured review of 26 Nordic studies from 1954 to 1993. Spine (Phila Pa 1976) 1995;20:2112–2118. doi: 10.1097/00007632-199510000-00009.
    1. Volinn E. The epidemiology of low back pain in the rest of the world: a review of surveys in low- and middle-income countries. Spine (Phila Pa 1976) 1997;22:1747–1754. doi: 10.1097/00007632-199708010-00013.
    1. Urwin M, Symmons D, Allison T, Brammah T, Busby H, Roxby M, Simmons A, Williams G. Estimating the burden of musculoskeletal disorders in the community: the comparative prevalence of symptoms at different anatomical sites, and the relation to social deprivation. Ann Rheum Dis. 1998;57:649–655. doi: 10.1136/ard.57.11.649.
    1. Walker BF. The prevalence of low back pain: a systematic review of the literature from 1966 to 1998. J Spinal Disord. 2000;13:205–217. doi: 10.1097/00002517-200006000-00003.
    1. Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bull World Health Organ. 2003;81:646–656.
    1. Silva MC, Fassa AG, Valle NC. Chronic low back pain in a southern Brazilian adult population: prevalence and associated factors. Cad Saúde Pública. 2004;20:377–385. doi: 10.1590/S0102-311X2004000200005.
    1. Louw QA, Morris LD, Grimmer-Somers K. The prevalence of low back pain in Africa: a systematic review. BMC Musculoskelet Disord. 2007;8:105. doi: 10.1186/1471-2474-8-105.
    1. Ferreira GD, Silva MC, Rombaldi AJ, Wrege ED, Siqueira FV, Hallal PC. Prevalence and associated factors of back pain in adults from southern Brazil: a population-based study. Rev Bras Fis. 2011;15:31–36. doi: 10.1590/S1413-35552011005000001.
    1. King S, Chambers CT, Huguet A, MacNevin RC, McGrath PJ, Parker L, MacDonald AJ. The epidemiology of chronic pain in children and adolescents revisited: a systematic review. Pain. 2011;152:2729–2738. doi: 10.1016/j.pain.2011.07.016.
    1. Garcia JB, Hernandez-Castro JJ, Nunez RG, Pazos MA, Aguirre JO, Jreige A, Delgado W, Serpentegui M, Berenguel M, Cantemir C. Prevalence of low back pain in Latin America: a systematic literature review. Pain Physician. 2014;17:379–391.
    1. Meucci RD, Fassa AG, Faria NM. Prevalence of chronic low back pain: systematic review. Rev Saude Publica. 2015;49:1-7.
    1. Jackson T, Thomas S, Stabile V, Shotwell M, Han X, McQueen K. A systematic review and meta-analysis of the global burden of chronic pain without clear etiology in low- and middle-income countries: trends in heterogeneous data and a proposal for new assessment methods. Anesth Analg. 2016;123:739–748. doi: 10.1213/ANE.0000000000001389.
    1. Jackson T, Thomas S, Stabile V, Han X, Shotwell M, McQueen KA. Chronic pain without clear etiology in low- and middle-income countries: a narrative review. Anesth Analg. 2016;122:2028–2039. doi: 10.1213/ANE.0000000000001287.
    1. Bikbov Mukharram, Fayzrakhmanov Rinat R, Kazakbaeva Gyulli, Jonas Jost B. Ural Eye and Medical Study: description of study design and methodology. Ophthalmic Epidemiology. 2017;25(3):187–198. doi: 10.1080/09286586.2017.1384504.
    1. Bikbov MM, Fayzrakhmanov RR, Kazakbaeva GM, Zainullin RM, Salavatova VF, Gilmanshin TR, Arslangareeva II, Nikitin NA, Panda-Jonas S, Mukhamadieva SR, Yakupova DF, Khikmatullin RI, Aminev SK, Nuriev IF, Zaynetdinov AF, Uzianbaeva YV, Jonas JB. Frequency and associated factors of bone fractures in Russians: the Ural eye and medical study. Sci Rep. 2018;8:7483. doi: 10.1038/s41598-018-25928-1.
    1. Bikbov MM, Kazakbaeva GM, Zainullin RM, Salavatova VF, Gilmanshin TR, Yakupova DF, Uzianbaeva YV, Arslangareeva II, Panda-Jonas S, Mukhamadieva SR, Khikmatullin RI, Aminev SK, Nuriev IF, Zaynetdinov AF, Jonas JB. Intraocular pressure and its associations in a Russian population: the Ural eye and medical study. Am J Ophthalmol. 2019;204:130–139. doi: 10.1016/j.ajo.2019.02.030.
    1. . Assessed 18.12.2019.
    1. Stevens GA, Alkema L, Black RE, Boerma JT, Collins GS, Ezzati M, Grove JT, Hogan DR, Hogan MC, Horton R, Lawn JE, Marušić A, Mathers CD, CJL M, Rudan I, Salomon JA, Simpson PJ, Vos T, Welch V, (the GATHER working group) Guidelines for accurate and transparent health estimates reporting: the GATHER statement. Lancet. 2016;388:e19–e23. doi: 10.1016/S0140-6736(16)30388-9.
    1. . Assessed 25.3.2018.
    1. Merskey H, Bogduk N. Classification of chronic pain. Descriptions of chronic pain syndromes and definitions of pain terms. 2. Seattle: IASP Press; 1994. p. 11.
    1. Aiello CP, Lima II, Ferrari DV. Validity and reliability of the hearing handicap inventory for adults. Braz J Otorhinolaryngol. 2011;77:432–438. doi: 10.1590/S1808-86942011000400005.
    1. Bikbov MM, Fayzrakhmanov RR, Kazakbaeva GM, Zainullin RM, Salavatova VF, Gilmanshin TR, Arslangareeva II, Nikitin NA, Panda-Jonas S, Mukhamadieva SR, Yakupova DF, Khikmatullin RI, Aminev SK, Nuriev IF, Zaynetdinov AF, Uzianbaeva YV, Jonas JB. Self-reported hearin26. g loss in Russians: the population-based Ural Eye and Medical Study. BMJ Open. 2019;9:e024644. doi: 10.1136/bmjopen-2018-024644.
    1. Vestbo J, Hurd SS, Agustí AG, Jones PW, Vogelmeier C, Anzueto A, Barnes PJ, Fabbri LM, Martinez FJ, Nishimura M, Stockley RA, Sin DD, Rodriguez-Roisin R. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2013;187:347–365. doi: 10.1164/rccm.201204-0596PP.
    1. . Assessed 1.9.2017.
    1. Noormohammadpour P, Mansournia MA, Koohpayehzadeh J, Asgari F, Rostami M, Rafei A, Kordi R. Prevalence of chronic neck pain, low back pain, and knee pain and their related factors in community-dwelling adults in Iran: a population-based national study. Clin J Pain. 2017;33:181–187. doi: 10.1097/AJP.0000000000000396.
    1. Leboeuf-Yde C, Nielsen J, Kyvik KO, Fejer R, Hartvigsen J. Pain in the lumbar, thoracic or cervical regions: do age and gender matter? A population-based study of 34,902 Danish twins 20-71 years of age. BMC Musculoskelet Disord. 2009;10:39. doi: 10.1186/1471-2474-10-39.
    1. Guez M, Hildingsson C, Nasic S, Toolanen G. Chronic low back pain in individuals with chronic neck pain of traumatic and non-traumatic origin: a population-based study. Acta Orthop. 2006;77:132–137. doi: 10.1080/17453670610045812.
    1. Genebra CVDS, Maciel NM, Bento TPF, Simeão SFAP, Vitta A. Prevalence and factors associated with neck pain: a population-based study. Braz J Phys Ther. 2017;21:274–280. doi: 10.1016/j.bjpt.2017.05.005.
    1. Fouquet N, Bodin J, Descatha A, Petit A, Ramond A, Ha C, Roquelaure Y. Prevalence of thoracic spine pain in a surveillance network. Occup Med (Lond) 2015;65:122–125. doi: 10.1093/occmed/kqu151.
    1. Dionne CE, Dunn KM, Croft PR. Does back pain prevalence really decrease with increasing age? A systematic review. Age Ageing. 2006;35:229–234. doi: 10.1093/ageing/afj055.
    1. Bjorck-van Dijken C, Fjellman-Wiklund A, Hildingsson C. Low back pain, lifestyle factors and physical activity: a population based-study. J Rehabil Med. 2008;40:864–869. doi: 10.2340/16501977-0273.
    1. Shiri R, Karppinen J, Leino-Arjas P, Solovieva S, Viikari-Juntura E. The association between obesity and low back pain: a meta-analysis. Am J Epidemiol. 2010;171:135–154. doi: 10.1093/aje/kwp356.
    1. Sitthipornvorakul E, Janwantanakul P, Purepong N, Pensri P, van der Beek AJ. The association between physical activity and neck and low back pain: a systematic review. Eur Spine J. 2011;20:677–689. doi: 10.1007/s00586-010-1630-4.
    1. Griffin DW, Harmon DC, Kennedy NM. Do patients with chronic low back pain have an altered level and/or pattern of physical activity compared to healthy individuals? A systematic review of the literature. Physiotherapy. 2012;98:13–23. doi: 10.1016/j.physio.2011.04.350.
    1. Shiri R, Falah-Hassani K. Does leisure time physical activity protect against low back pain? Systematic review and meta-analysis of 36 prospective cohort studies. Br J Sports Med. 2017;51:1410–1418. doi: 10.1136/bjsports-2016-097352.
    1. Shiri R, Karppinen J, Leino-Arjas P, Solovieva S, Viikari-Juntura E. The association between smoking and low back pain: a meta-analysis. Am J Med. 2010;123:87.e7–87.35. doi: 10.1016/j.amjmed.2009.05.028.
    1. Paulis WD, Silva S, Koes BW, van Middelkoop M. Overweight and obesity are associated with musculoskeletal complaints as early as childhood: a systematic review. Obes Rev. 2014;15:52–67. doi: 10.1111/obr.12067.

Source: PubMed

Sponsorer og samarbeidspartnere

Medisinsk tilstand

Legemiddelintervensjoner

3
Abonnere