Antibiotic Prophylaxis on Third Molar Extraction: Systematic Review of Recent Data

Gabriele Cervino, Marco Cicciù, Antonio Biondi, Salvatore Bocchieri, Alan Scott Herford, Luigi Laino, Luca Fiorillo, Gabriele Cervino, Marco Cicciù, Antonio Biondi, Salvatore Bocchieri, Alan Scott Herford, Luigi Laino, Luca Fiorillo

Abstract

The aim of this paper was to highlight the most widely antibiotic protocols applied to the dental field, especially in the surgical treatment of impacted wisdom teeth. Once these protocols were screened, all the possible advantages or disadvantages for each drug and each posology were recorded in this review. In recent years, the need to use these protocols has been debated in the literature. The data obtained by this review underlined how antibiotic protocols applied to oral surgery treatments only included surgeries performed on patients who did not present other systemic pathologies. The first literature review obtained 140 results, and then after the application of the inclusion criteria, 12 papers were selected. The results showed that the most commonly used protocol involved the use of penicillin and clavulanate, obtaining safe clinical and prophylactic results in the management of infections. This widely used protocol seems to guarantee high predictability and safety. The presented review highlights the current possibility of antibiotic resistance affecting patients due to drug misuse. Further clinical studies are required to state specific guidelines; however, oral surgeons involved in third molar surgery should evaluate the local and general health conditions of the patients before suggesting any drug measures for patients.

Keywords: antibiotic; extraction; oral surgery; prophylaxis; third molar.

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
PRISMA (Preferred Reporting Items for Systematic Reviews and Meta- Analyses) flow diagram. RCT: randomized controlled trial.

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