CT Imaging and Differential Diagnosis of COVID-19

Wei-Cai Dai, Han-Wen Zhang, Juan Yu, Hua-Jian Xu, Huan Chen, Si-Ping Luo, Hong Zhang, Li-Hong Liang, Xiao-Liu Wu, Yi Lei, Fan Lin, Wei-Cai Dai, Han-Wen Zhang, Juan Yu, Hua-Jian Xu, Huan Chen, Si-Ping Luo, Hong Zhang, Li-Hong Liang, Xiao-Liu Wu, Yi Lei, Fan Lin

Abstract

Since the beginning of 2020, coronavirus disease 2019 (COVID-19) has spread throughout China. This study explains the findings from lung computed tomography images of some patients with COVID-19 treated in this medical institution and discusses the difference between COVID-19 and other lung diseases.

Keywords: 2019n-CoV; COVID19; CT; lung diseases; pneumonia.

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
A 52-year-old male: Computed tomography scan revealed patchy pure ground-glass opacities (red arrow) at the lateral basal segment of the right lower lobe and vascular dilation inside the lesion.
Figure 2.
Figure 2.
A 63-year-old male: High-resolution computed tomography scan showed multiple pure ground-glass opacities in the right lower lobe, a distribution of lesions in the subpleural area and lung periphery, a “crazy-paving” pattern, and interlobular septal thickening (red arrow).
Figure 3.
Figure 3.
A 48-year-old male: High-resolution computed tomography scan showed multiple ground-glass opacities in multiple lobes of both lungs, interlobular septal thickening, and a crazy-paving pattern (red arrow).
Figure 4.
Figure 4.
A 47-year-old male: High-resolution computed tomography scan showed patchy consolidations on the left upper lobe, partially consolidated lung tissue, ground-glass opacities on the edge, and air bronchograms in the lesion (red arrow).
Figure 5.
Figure 5.
A 60-year-old female: High-resolution chest computed tomography scan revealed extensive patchy exudates and consolidation of both lungs, faint ground-glass opacities on the edge, and interlobular septal thickening (red arrow).
Figure 6.
Figure 6.
A 58-year-old female: High-resolution chest CT showed extensive GGOs in both lungs, which were mainly distributed along the hila, interlobular septal thickening, and interlobar pleural thickening (red arrow).

References

    1. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;383(8):727–733.
    1. Corman VM, Landt O, Kaiser M, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020;25(3).
    1. Koo HJ, Lim S, Choe J, Choi SH, Sung H, Do KH. Radiographic and CT features of viral pneumonia. Radiographics. 2018;38(3):719–739.
    1. Wan Y, Shang J, Graham R, Baric RS, Li F. Receptor recognition by novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS. J Virol. 2020;94(7). doi:10.1128/JVI.00127-20.
    1. Garg M, Prabhakar N, Gulati A, Agarwal R, Dhooria S. Spectrum of imaging findings in pulmonary infections. Part 1: Bacterial and viral. Pol J Radiol. 2019;84:e205–e13.
    1. Bassetti M, Vena A, Roberto Giacobbe D. The novel Chinese coronavirus (2019-nCoV) infections: challenges for fighting the storm. Eur J Clin Invest. 2020:e13209.
    1. Kishaba T. Community-acquired pneumonia caused by Mycoplasma pneumoniae: how physical and radiological examination contribute to successful diagnosis. Front Med (Lausanne). 2016;3:28.
    1. Zhao S, Lin Q, Ran J, et al. Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: a data-driven analysis in the early phase of the outbreak. Int J Infect Dis. 2020;92:214–217.
    1. Ishiguro T, Kobayashi Y, Uozumi R, et al. Viral pneumonia requiring differentiation from acute and progressive diffuse interstitial lung diseases. Intern Med. 2019;58(24):3509–3519.
    1. Yoo JH. The fight against the 2019-nCoV outbreak: an arduous march has just begun. J Korean Med Sci. 2020;35(4):e56.
    1. Lu H, Stratton CW, Tang YW. Outbreak of pneumonia of unknown etiology in Wuhan, China: the mystery and the miracle. J Med Virol. 2020;92(4):401–402.
    1. Wang W, Tang J, Wei F. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China. J Med Virol. 2020;92(4):441–447.

Source: PubMed

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