Rubber band ligation of hemorrhoids: A guide for complications

Andreia Albuquerque, Andreia Albuquerque

Abstract

Rubber band ligation is one of the most important, cost-effective and commonly used treatments for internal hemorrhoids. Different technical approaches were developed mainly to improve efficacy and safety. The technique can be employed using an endoscope with forward-view or retroflexion or without an endoscope, using a suction elastic band ligator or a forceps ligator. Single or multiple ligations can be performed in a single session. Local anaesthetic after ligation can also be used to reduce the post-procedure pain. Mild bleeding, pain, vaso-vagal symptoms, slippage of bands, priapism, difficulty in urination, anal fissure, and chronic longitudinal ulcers are normally considered minor complications, more frequently encountered. Massive bleeding, thrombosed hemorrhoids, severe pain, urinary retention needing catheterization, pelvic sepsis and death are uncommon major complications. Mild pain after rubber band ligation is the most common complication with a high frequency in some studies. Secondary bleeding normally occurs 10 to 14 d after banding and patients taking anti-platelet and/or anti-coagulant medication have a higher risk, with some reports of massive life-threatening haemorrhage. Several infectious complications have also been reported including pelvic sepsis, Fournier's gangrene, liver abscesses, tetanus and bacterial endocarditis. To date, seven deaths due to these infectious complications were described. Early recognition and immediate treatment of complications are fundamental for a favourable prognosis.

Keywords: Bleeding; Hemorrhoids; Infection; Pain; Rubber band ligation.

Conflict of interest statement

Conflict-of-interest statement: There is no financial support or relationships that may pose conflict of interest to declare.

References

    1. Blaisdell PC. Office ligation of internal hemorrhoids. Am J Surg. 1958;96:401–404.
    1. Barron J. Office ligation of internal hemorrhoids. Am J Surg. 1963;105:563–570.
    1. Siddiqui UD, Barth BA, Banerjee S, Bhat YM, Chauhan SS, Gottlieb KT, Konda V, Maple JT, Murad FM, Pfau P, et al. Devices for the endoscopic treatment of hemorrhoids. Gastrointest Endosc. 2014;79:8–14.
    1. MacRae HM, McLeod RS. Comparison of hemorrhoidal treatment modalities. A meta-analysis. Dis Colon Rectum. 1995;38:687–694.
    1. Johanson JF, Rimm A. Optimal nonsurgical treatment of hemorrhoids: a comparative analysis of infrared coagulation, rubber band ligation, and injection sclerotherapy. Am J Gastroenterol. 1992;87:1600–1606.
    1. Shanmugam V, Thaha MA, Rabindranath KS, Campbell KL, Steele RJ, Loudon MA. Rubber band ligation versus excisional haemorrhoidectomy for haemorrhoids. Cochrane Database Syst Rev. 2005;(3):CD005034.
    1. Kanellos I, Goulimaris I, Christoforidis E, Kelpis T, Betsis D. A comparison of the simultaneous application of sclerotherapy and rubber band ligation, with sclerotherapy and rubber band ligation applied separately, for the treatment of haemorrhoids: a prospective randomized trial. Colorectal Dis. 2003;5:133–138.
    1. Accarpio G, Ballari F, Puglisi R, Menoni S, Ravera G, Accarpio FT, Cariati A, Zaffarano R. Outpatient treatment of hemorrhoids with a combined technique: results in 7850 cases. Tech Coloproctol. 2002;6:195–196.
    1. Chew SS, Marshall L, Kalish L, Tham J, Grieve DA, Douglas PR, Newstead GL. Short-term and long-term results of combined sclerotherapy and rubber band ligation of hemorrhoids and mucosal prolapse. Dis Colon Rectum. 2003;46:1232–1237.
    1. Iyer VS, Shrier I, Gordon PH. Long-term outcome of rubber band ligation for symptomatic primary and recurrent internal hemorrhoids. Dis Colon Rectum. 2004;47:1364–1370.
    1. Bat L, Melzer E, Koler M, Dreznick Z, Shemesh E. Complications of rubber band ligation of symptomatic internal hemorrhoids. Dis Colon Rectum. 1993;36:287–290.
    1. Longman RJ, Thomson WH. A prospective study of outcome from rubber band ligation of piles. Colorectal Dis. 2006;8:145–148.
    1. Komborozos VA, Skrekas GJ, Pissiotis CA. Rubber band ligation of symptomatic internal hemorrhoids: results of 500 cases. Dig Surg. 2000;17:71–76.
    1. Wechter DG, Luna GK. An unusual complication of rubber band ligation of hemorrhoids. Dis Colon Rectum. 1987;30:137–140.
    1. El Nakeeb AM, Fikry AA, Omar WH, Fouda EM, El Metwally TA, Ghazy HE, Badr SA, Abu Elkhar MY, Elawady SM, Abd Elmoniam HH, et al. Rubber band ligation for 750 cases of symptomatic hemorrhoids out of 2200 cases. World J Gastroenterol. 2008;14:6525–6530.
    1. Bursics A, Weltner J, Flautner LE, Morvay K. Ano-rectal physiological changes after rubber band ligation and closed haemorrhoidectomy. Colorectal Dis. 2004;6:58–61.
    1. Izadpanah A, Hosseini S, Mahjoob M. Comparison of electrotherapy, rubber band ligation and hemorrhoidectomy in the treatment of hemorrhoids: a clinical and manometric study. Middle East J Dig Dis. 2010;2:9–13.
    1. Odelowo OO, Mekasha G, Johnson MA. Massive life-threatening lower gastrointestinal hemorrhage following hemorrhoidal rubber band ligation. J Natl Med Assoc. 2002;94:1089–1092.
    1. Beattie GC, Rao MM, Campbell WJ. Secondary haemorrhage after rubber band ligation of haemorrhoids in patients taking clopidogrel--a cautionary note. Ulster Med J. 2004;73:139–141.
    1. Parker R, Gul R, Bucknall V, Bowley D, Karandikar S. Double jeopardy: pyogenic liver abscess and massive secondary rectal haemorrhage after rubber band ligation of haemorrhoids. Colorectal Dis. 2011;13:e184.
    1. Patel S, Shahzad G, Rizvon K, Subramani K, Viswanathan P, Mustacchia P. Rectal ulcers and massive bleeding after hemorrhoidal band ligation while on aspirin. World J Clin Cases. 2014;2:86–89.
    1. Marshman D, Huber PJ, Timmerman W, Simonton CT, Odom FC, Kaplan ER. Hemorrhoidal ligation. A review of efficacy. Dis Colon Rectum. 1989;32:369–371.
    1. Nelson RS, Ewing BM, Ternent C, Shashidharan M, Blatchford GJ, Thorson AG. Risk of late bleeding following hemorrhoidal banding in patients on antithrombotic prophylaxis. Am J Surg. 2008;196:994–999; discussion 999.
    1. Sajid MS, Bhatti MI, Caswell J, Sains P, Baig MK. Local anaesthetic infiltration for the rubber band ligation of early symptomatic haemorrhoids: a systematic review and meta-analysis. Updates Surg. 2015;67:3–9.
    1. Hooker GD, Plewes EA, Rajgopal C, Taylor BM. Local injection of bupivacaine after rubber band ligation of hemorrhoids: prospective, randomized study. Dis Colon Rectum. 1999;42:174–179.
    1. Watson NF, Liptrott S, Maxwell-Armstrong CA. A prospective audit of early pain and patient satisfaction following out-patient band ligation of haemorrhoids. Ann R Coll Surg Engl. 2006;88:275–279.
    1. Khubchandani IT. A randomized comparison of single and multiple rubber band ligations. Dis Colon Rectum. 1983;26:705–708.
    1. Guy RJ, Seow-Choen F. Septic complications after treatment of haemorrhoids. Br J Surg. 2003;90:147–156.
    1. McCloud JM, Jameson JS, Scott AN. Life-threatening sepsis following treatment for haemorrhoids: a systematic review. Colorectal Dis. 2006;8:748–755.
    1. Clay LD, White JJ, Davidson JT, Chandler JJ. Early recognition and successful management of pelvic cellulitis following hemorrhoidal banding. Dis Colon Rectum. 1986;29:579–581.
    1. Shemesh EI, Kodner IJ, Fry RD, Neufeld DM. Severe complication of rubber band ligation of internal hemorrhoids. Dis Colon Rectum. 1987;30:199–200.
    1. Russell TR, Donohue JH. Hemorrhoidal banding. A warning. Dis Colon Rectum. 1985;28:291–293.
    1. LeFrock JL, Ellis CA, Turchik JB, Weinstein L. Transient bacteremia associated with sigmoidoscopy. N Engl J Med. 1973;289:467–469.
    1. Dickman MD, Farrell R, Higgs RH, Wright LE, Humphries TJ, Wojcik JD, Chappelka R. Colonoscopy associated bacteremia. Surg Gynecol Obstet. 1976;142:173–176.
    1. Hoffman BI, Kobasa W, Kaye D. Bacteremia after rectal examination. Ann Intern Med. 1978;88:658–659.
    1. Bonardi RA, Rosin JD, Stonesifer GL, Bauer FW. Bacteremias associated with routine hemorrhoidectomies. Dis Colon Rectum. 1976;19:233–236.
    1. Adami B, Eckardt VF, Suermann RB, Karbach U, Ewe K. Bacteremia after proctoscopy and hemorrhoidal injection sclerotherapy. Dis Colon Rectum. 1981;24:373–374.
    1. Quevedo-Bonilla G, Farkas AM, Abcarian H, Hambrick E, Orsay CP. Septic complications of hemorrhoidal banding. Arch Surg. 1988;123:650–651.
    1. Scarpa FJ, Hillis W, Sabetta JR. Pelvic cellulitis: a life-threatening complication of hemorrhoidal banding. Surgery. 1988;103:383–385.
    1. Buchmann P, Seefeld U. Rubber band ligation for piles can be disastrous in HIV-positive patients. Int J Colorectal Dis. 1989;4:57–58.
    1. Duchateau A, Huyghe M. Perirectal sepsis after rubber band ligation of haemorrhoids: a case report. Acta Chir Belg. 2014;114:344–348.
    1. Subramaniam D, Hureibi K, Zia K, Uheba M. The development of Fournier’s gangrene following rubber band ligation of haemorrhoids. BMJ Case Rep. 2013;2013
    1. Parikh SR, Molinelli B, Dailey TH. Liver abscess after hemorrhoidectomy. Report of two cases. Dis Colon Rectum. 1994;37:185–189.
    1. Mohammedi I, Duperret S, Faysse E, Vedrinne JM, Motin J. [Liver abscess caused by Streptococcus intermedius, following hemorrhoidectomy] Ann Fr Anesth Reanim. 1996;15:1090–1091.
    1. Murray-Lyon IM, Kirkham JS. Hepatic abscesses complicating injection sclerotherapy of haemorrhoids. Eur J Gastroenterol Hepatol. 2001;13:971–972.
    1. Ku JJ, Marfan M, Wall D. Pyogenic liver abscess after haemorrhoidal banding. ANZ J Surg. 2005;75:828–830.
    1. Wiese L, Nielsen X, Andresen K, Kjaer A, David K. 16S rDNA sequencing revealed Citrobacter freundii as the cause of liver abcess after banding of rectal haemorrhoids. J Infect. 2005;50:163–164.
    1. Ergas D, Abdul-Hai A, Sthoeger Z, Menahem BH, Miller R. Multiple pyogenic liver abscesses following hemorrhoid banding. Isr Med Assoc J. 2007;9:753–754.
    1. Chau NG, Bhatia S, Raman M. Pylephlebitis and pyogenic liver abscesses: a complication of hemorrhoidal banding. Can J Gastroenterol. 2007;21:601–603.
    1. Xu M, Russell M, Lin A, Yoo J. Pyogenic liver abscess as a complication of internal hemorrhoid banding. Am Surg. 2014;80:E36–E37.
    1. Murphy KJ. Tetanus after rubber-band ligation of haemorrhoids. Br Med J. 1978;1:1590–1591.
    1. Kasher JA, Mathisen G. Acquiring tetanus after hemorrhoid banding and other gastrointestinal procedures. J Gastrointest Surg. 2007;11:515–519.
    1. Tejirian T, Abbas MA. Bacterial endocarditis following rubber band ligation in a patient with a ventricular septal defect: report of a case and guideline analysis. Dis Colon Rectum. 2006;49:1931–1933.
    1. O’Hara VS. Fatal clostridial infection following hemorrhoidal banding. Dis Colon Rectum. 1980;23:570–571.
    1. Sim HL, Tan KY, Poon PL, Cheng A, Mak K. Life-threatening perineal sepsis after rubber band ligation of haemorrhoids. Tech Coloproctol. 2009;13:161–164.
    1. Moore BA, Fleshner PR. Rubber band ligation for hemorrhoidal disease can be safely performed in select HIV-positive patients. Dis Colon Rectum. 2001;44:1079–1082.
    1. Jeffery PJ, Parks AG, Ritchie JK. Treatment of haemorrhoids in patients with inflammatory bowel disease. Lancet. 1977;1:1084–1085.
    1. D’Ugo S, Franceschilli L, Cadeddu F, Leccesi L, Blanco Gdel V, Calabrese E, Milito G, Di Lorenzo N, Gaspari AL, Sileri P. Medical and surgical treatment of haemorrhoids and anal fissure in Crohn’s disease: a critical appraisal. BMC Gastroenterol. 2013;13:47.
    1. Ramzisham AR, Sagap I, Nadeson S, Ali IM, Hasni MJ. Prospective randomized clinical trial on suction elastic band ligator versus forceps ligator in the treatment of haemorrhoids. Asian J Surg. 2005;28:241–245.
    1. Lee HH, Spencer RJ, Beart RW. Multiple hemorrhoidal bandings in a single session. Dis Colon Rectum. 1994;37:37–41.
    1. Poon GP, Chu KW, Lau WY, Lee JM, Yeung C, Fan ST, Yiu TF, Wong SH, Wong KK. Conventional vs. triple rubber band ligation for hemorrhoids. A prospective, randomized trial. Dis Colon Rectum. 1986;29:836–838.
    1. Trowers EA, Ganga U, Rizk R, Ojo E, Hodges D. Endoscopic hemorrhoidal ligation: preliminary clinical experience. Gastrointest Endosc. 1998;48:49–52.
    1. Berkelhammer C, Moosvi SB. Retroflexed endoscopic band ligation of bleeding internal hemorrhoids. Gastrointest Endosc. 2002;55:532–537.
    1. Fukuda A, Kajiyama T, Arakawa H, Kishimoto H, Someda H, Sakai M, Tsunekawa S, Chiba T. Retroflexed endoscopic multiple band ligation of symptomatic internal hemorrhoids. Gastrointest Endosc. 2004;59:380–384.
    1. Wehrmann T, Riphaus A, Feinstein J, Stergiou N. Hemorrhoidal elastic band ligation with flexible videoendoscopes: a prospective, randomized comparison with the conventional technique that uses rigid proctoscopes. Gastrointest Endosc. 2004;60:191–195.
    1. Cazemier M, Felt-Bersma RJ, Cuesta MA, Mulder CJ. Elastic band ligation of hemorrhoids: flexible gastroscope or rigid proctoscope? World J Gastroenterol. 2007;13:585–587.
    1. Law WL, Chu KW. Triple rubber band ligation for hemorrhoids: prospective, randomized trial of use of local anesthetic injection. Dis Colon Rectum. 1999;42:363–366.
    1. Kwok HC, Noblett SE, Murray NE, Merrie AE, Hayes JL, Bissett IP. The use of local anaesthesia in haemorrhoidal banding: a randomized controlled trial. Colorectal Dis. 2013;15:487–491.

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