An increased prevalence of self-reported allergic rhinitis in major Chinese cities from 2005 to 2011

X D Wang, M Zheng, H F Lou, C S Wang, Y Zhang, M Y Bo, S Q Ge, N Zhang, L Zhang, C Bachert, X D Wang, M Zheng, H F Lou, C S Wang, Y Zhang, M Y Bo, S Q Ge, N Zhang, L Zhang, C Bachert

Abstract

Background: The prevalence of allergic rhinitis (AR) has increased worldwide in recent decades. This study was conducted to investigate the prevalence of self-reported AR and profiles of AR-related comorbidities in the adult population of China over time.

Methods: This study surveyed residents of 18 major cities in mainland China. Telephone interviews were conducted with study participants after sampling target telephone numbers by random digit dialing. The questions asked during telephone interviews were based on those included in validated questionnaires and focused on topics regarding AR, nonallergic rhinitis (NAR), acute/chronic rhinosinusitis (ARS/CRS), asthma, and atopic dermatitis (AD).

Results: During 2011, a total of 47 216 telephone interviews were conducted, and the overall response rate was 77.5%. When compared with the AR prevalence in 11 cities surveyed in 2005, there was a significant increase in self-reported adult AR in eight of those cities (P < 0.01). In 2011, the standardized prevalence of self-reported adult AR in the 18 cities was 17.6%. The concentration of SO2 was positively correlated with the prevalence of AR (r = 0.504, P = 0.033). A multiple regression model showed that the absolute change in household yearly income was significantly associated with the change in the prevalence of AR (R(2) = 0.68), after adjusting for PM10 , SO2 , NO2, temperature, and humidity. The overall prevalences of NAR, ARS, CRS, asthma, and AD in the general population were 16.4%, 5.4%, 2.1%, 5.8%, and 14%, respectively.

Conclusion: During a 6-year period, there was a significant increase in the prevalence of self-reported AR in the general Chinese adult population. The incidence of AR being accompanied by rhinosinusitis, asthma, or AD was significantly higher among individuals having self-reported AR compared with the general population.

Keywords: asthma; increase over time; prevalence; rhinosinusitis; self-reported allergic rhinitis.

© 2016 The Authors. Allergy Published by John Wiley & Sons Ltd.

Figures

Figure 1
Figure 1
Locations of the 18 major cities in mainland China selected for inclusion in the present study. The number given for each city represents its population (millions of inhabitants) in 2010. Abbreviations: BJ, Beijing; CC, Changchun; CD, Chengdu; CS, Changsha; FZ, Fuzhou; GZ, Guangzhou; HK, Haikou; HZ, Hangzhou; H, Hohhot; KM, Kunming; NJ, Nanjing; SH, Shanghai; SY, Shenyang; U, Urumqi; WH, Wuhan; XA, Xi'An; YC, Yinchuan; ZZ, Zhengzhou.
Figure 2
Figure 2
Comparisons of the standardized prevalences of self‐reported allergic rhinitis (AR) in 11 major cities between 2005 and 2011. (*P < 0.001, # P < 0.01; Table 1 shows the P‐values for comparisons between 2005 and 2011.)
Figure 3
Figure 3
Comorbidity of self‐reported asthma, acute rhinosinusitis, chronic rhinosinusitis, and atopic dermatitis in the total population, and allergic rhinitis (AR) and non‐AR subpopulations (*P < 0.001).
Figure 4
Figure 4
Comorbidity of self‐reported allergic rhinitis, nonallergic rhinitis, acute rhinosinusitis, chronic rhinosinusitis, and atopic dermatitis in the total population and asthma population (*P < 0.001).

References

    1. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 Update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008;63(Suppl. 86):8–160.
    1. Leynaert B, Neukirch C, Kony S, Guenegou A, Bousquet J, Aubier M et al. Association between asthma and rhinitis according to atopic sensitization in a population‐based study. J Allergy Clin Immunol 2004;113:86–93.
    1. Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross‐sectional surveys. Lancet 2006;368:733–743.
    1. Zhang L, Han D, Huang D, Wu Y, Dong Z, Xu G et al. Prevalence of self‐reported allergic rhinitis in eleven major cities in china. Int Arch Allergy Immunol 2009;149:47–57.
    1. Sa‐Sousa A, Morais‐Almeida M, Azevedo LF, Carvalho R, Jacinto T, Todo‐Bom A et al. Prevalence of asthma in Portugal – The Portuguese National Asthma Survey. Clin Transl Allergy 2012;2:15.
    1. Eriksson J, Ekerljung L, Rönmark E, Dahlén B, Ahlstedt S, Dahlén SE et al. Update of prevalence of self‐reported allergic rhinitis and chronic nasal symptoms among adults in Sweden. Clin Respir J 2012;6:159–168.
    1. China Statistical Yearbook (2012 and 2006). Available at: . Published by China Statistical Press.
    1. Blanc PD, Yen IH, Chen H, Katz PP, Earnest G, Balmes JR et al. Area‐level socio‐economic status and health status among adults with asthma and rhinitis. Eur Respir J 2006;27:85–94.
    1. Asher MI, Keil U, Anderson HR, Beasley R, Crane J, Martinez F et al. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J 1995;8:483–491.
    1. Burney P, Chinn S, Jarvis D, Luczynska C, Lai E, European Community Respiratory Health Survey . Variations in the prevalence of respiratory symptoms, self‐reported asthma attacks, and use of asthma medication in the European Community Respiratory Health Survey(ECRHS). Eur Respir J 1996;9:687–695.
    1. Wallace DV, Dykewicz MS, Bernstein DI, Blessing‐Moore J, Cox L, Khan DA et al. The diagnosis and management of rhinitis: an updated practice parameter. J Allergy Clin Immunol 2008;122:S1–S84.
    1. Tomassen P, Newson RB, Hoffmans R, Lotvall J, Cardell LO, Gunnbjornsdottir M et al. Reliability of EP3OS symptom criteria and nasal endoscopy in the assessment of chronic rhinosinusitis – a GA2LEN study. Allergy 2011;66:556–561.
    1. Fokkens W, Lund V, Mullol J. European position paper on rhinosinusitis and nasal polyps 1007. Rhinology 2007;45(Suppl. 20):1–136.
    1. de Marco R, Zanolin ME, Accordini S, Signorelli D, Marinoni A, Bugiani M et al. A new questionnaire for the repeat of the first stage of the European Community Respiratory Health Survey: a pilot study. Eur Respir J 1999;14:1044–1048.
    1. Saunes M, Smidesang I, Holmen TL, Johnsen R. Atopic dermatitis in adolescent boys is associated with greater psychological morbidity compared with girls of the same age: the Young‐HUNT study. Br J Dermatol 2007;156:283–288.
    1. De Zwaan M, Hilbert A, Herpertz S, Zipfel S, Beutel M, Gefeller O et al. Weight loss maintenance in a population‐based sample of German adults. Obesity 2008;16:2535–2540.
    1. Bousquet PJ, Leynaert B, Neukirch F, Sunyer J, Janson CM, Anto J et al. Geographical distribution of atopic rhinitis in the European community Respiratory Health Survey I. Allergy 2008;63:1301–1309.
    1. Burns JS, Dockery DW, Neas LM, Schwartz J, Coull BA, Raizenne M et al. Low dietary nutrient intakes and respiratory health in adolescents. Chest 2007;132:238–245.
    1. Kan H, Chen R, Tong S. Ambient air pollution, climate change, and population health in China. Environ Int 2012;42:10–19.
    1. Xu P, Chen CY, Ye X. Haze, air pollution, and health in China. Lancet 2013;382:2067.
    1. Lee SY, Chang YS, Cho SH. Allergic rhinitis and air pollution. Asia Pac Allergy 2013;3:145–154.
    1. D'Amato G, Cecchi L. Effects of climate change on environmental factors in respiratory allergic diseases. Clin Exp Allergy 2008;38:1264–1274.
    1. Diaz‐Sanchez D, Garcia MP, Wang M, Jyrala M, Saxon A. Nasal challenge with diesel exhaust particles can induce sensitization to a neoallergen in the human mucosa. J Allergy Clin Immunol 1999;104:1183–1188.
    1. Diaz‐Sanchez D, Tsien A, Casillas A, Dotson AR, Saxon A. Enhanced nasal cytokine production in human beings after in vivo challenge with diesel exhaust particles. J Allergy Clin Immunol 1996;98:114–123.
    1. Lehmann I, Rehwagen M, Diez U, Seiffart A, Rolle‐Kampczyk U, Richter M et al. Enhanced in vivo IgE production and T cell polarization toward the type 2 phenotype in association with indoor exposure to VOC: results of the LARS study. Int J Hyg Environ Health 2001;204:211–221.
    1. Dong GH, Qian ZM, Wang J, Trevathan E, Ma W, Chen W et al. Residential characteristics and household risk factors and respiratory diseases in Chinese women: The Seven Northeast Cities (SNEC) Study. Sci Total Environ 2013;463–464:389–394.
    1. Jaakkola JJ, Ieromnimon A, Jaakkola MS. Interior surface materials and asthma in adults: a population‐based incident case–control study. Am J Epidemiol 2006;164:742–749.
    1. Strachan DP. Hay fever, hygiene, and household size. BMJ 1989;299:1259–1260.
    1. Bauchau V, Durham SR. Epidemiological characterization of the intermittent and persistent types of allergic rhinitis. Allergy 2005;60:350–353.
    1. Antonicelli L, Micucci C, Voltolini S, Feliziani V, Senna GE, Blasi PD et al. Allergic rhinitis and asthma comorbidity: ARIA classification of rhinitis does not correlate with the prevalence of asthma. Clin Exp Allergy 2007;37:954–960.
    1. Bousquet J, Neukirch F, Bousquet PJ, Gehano P, Klossek JM, Le Gal M et al. Severity and impairment of allergic rhinitis in patients consulting in primary care. J Allergy Clin Immunol 2006;117:158–162.
    1. Li J, Sun B, Huang Y, Lin X, Zhao D, Tan G et al. A multicentre study assessing the prevalence of sensitizations in patients with asthma and/or rhinitis in China. Allergy 2009;64:1083–1092.
    1. Wang C, Zhang L, Han D, Zhou B, Zhao Y, Wang X. Prevalence of sensitization to aeroallergens in Beijing patients with allergic rhinitis. Lin Chuang Er Bi Yan Hou Ke Za Zhi 2006;20:204–207.
    1. Settipane RA. Demographics and epidemiology of allergic and nonallergic rhinitis. Allergy Asthma Proc 2001;22:185–189.
    1. Enberg RN. Perennial nonallergic rhinitis: a retrospective review. Ann Allergy Asthma Immunol 1989;63:513–516.
    1. Togias A. Age relationships and clinical features of nonallergic rhinitis. J Allergy Clin Immunol 1990;85:182.
    1. Jarvis D, Newson R, Lotvall J, Hastan D, Tomassen P, Keil T et al. Asthma in adults and its association with chronic rhinosinusitis: the GA2LEN survey in Europe. Allergy 2012;67:91–98.
    1. Bousquet J, Vignola AM, Demoly P. Links between rhinitis and asthma. Allergy 2003;58:691–706.
    1. Emanuel IA, Shah SB. Chronic rhinosinusitis: allergy and sinus computed tomography relationships. Otolaryngol Head Neck Surg 2000;123:687–691.
    1. Yariktas M, Doner F, Demirici M. Rhinosinusitis among the patients with perennial or seasonal allergic rhinitis. Asian Pac J Allergy Immunol 2003;21:75–78.
    1. Kennedy DW. Prognostic factors, outcomes and staging in ethmoid sinus surgery. Laryngoscope 1992;102(12 Pt 2 Suppl. 57):1–18.
    1. Shi JB, Fu QL, Zhang H, Cheng L, Wang YJ, Zhu DD et al. Epidemiology of chronic rhinosinusitis: results from a cross‐sectional survey in seven Chinese cities. Allergy 2015;70:633–639.

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