Living with tics: reduced impairment and improved quality of life for youth with chronic tic disorders

Joseph F McGuire, Elysse Arnold, Jennifer M Park, Joshua M Nadeau, Adam B Lewin, Tanya K Murphy, Eric A Storch, Joseph F McGuire, Elysse Arnold, Jennifer M Park, Joshua M Nadeau, Adam B Lewin, Tanya K Murphy, Eric A Storch

Abstract

Pharmacological and behavioral interventions have focused on reducing tic severity to alleviate tic-related impairment for youth with chronic tic disorders (CTDs), with no existing intervention focused on the adverse psychosocial consequences of tics. This study examined the preliminary efficacy of a modularized cognitive behavioral intervention ("Living with Tics", LWT) in reducing tic-related impairment and improving quality of life relative to a waitlist control of equal duration. Twenty-four youth (ages 7-17 years) with Tourette Disorder or Chronic Motor Tic Disorder and psychosocial impairment participated. A treatment-blind evaluator conducted all pre- and post-treatment clinician-rated measures. Youth were randomly assigned to receive the LWT intervention (n=12) or a 10-week waitlist (n=12). The LWT intervention consisted of up to 10 weekly sessions targeted at reducing tic-related impairment and developing skills to manage psychosocial consequences of tics. Youth in the LWT condition experienced significantly reduced clinician-rated tic-impairment, and improved child-rated quality of life. Ten youth (83%) in the LWT group were classified as treatment responders compared to four youth in the waitlist condition (33%). Treatment gains were maintained at one-month follow-up. Findings provide preliminary data that the LWT intervention reduces tic-related impairment and improves quality of life for youth with CTDs.

Keywords: Chronic tic disorders; Cognitive behavior therapy; Functional impairment; Quality of life; Tourette Disorder; Treatment outcome.

Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Figures

Figure 1
Figure 1
Flow of patients through the study, LWT indicates Living with Tics treatment protocol.

Source: PubMed

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