Pharmacokinetic Drug Interaction Study in Healthy Male Subjects

Inclusion Criteria:

• Is a healthy male between 20 and 50 years old
• Has BMI result between 19 and 26 kg/m2 at screening; and a total body weight over 55 kg. BMI(kg/m2) = body weight(kg)/{height(m)}2.
• Is willing and able to comply with scheduled visits, treatment plan, laboratory tests, and other study procedures
• Agrees to use an adequate means of contraception during clinical trials

Exclusion Criteria:

• Subjects with evidence or history of clinically significant hepatic, renal, digestive, neurologic, pulmonary, musculoskeletal, endocrine, hematological, cardiovascular or psychiatric disease
• Subjects with evidence or history of gastrointestinal disease or surgery possibly affecting drug absorption.
• Subjects with history of hypersensitivities or clinically significant adverse events caused by DPPIV inhibitors, ketoconazole, rifampicin, and other drugs
• Subjects who have donated a unit of blood within 60 days or blood components within 30 days before the first administration of the investigational product.
• Subjects who consume excessive alcohol or caffeine; who excessively smoke