Neuromuscular ultrasound in clinical practice: A review

Natalia L Gonzalez, Lisa D Hobson-Webb, Natalia L Gonzalez, Lisa D Hobson-Webb

Abstract

Neuromuscular ultrasound (NMUS) is becoming a standard element in the evaluation of peripheral nerve and muscle disease. When obtained simultaneously to electrodiagnostic studies, it provides dynamic, structural information that can refine a diagnosis or identify a structural etiology. NMUS can improve patient care for those with mononeuropathies, polyneuropathy, motor neuron disease and muscle disorders. In this article, we present a practical guide to the basics of NMUS and its clinical application. Basic ultrasound physics, scanning techniques and clinical applications are reviewed, along with current challenges.

Keywords: CIDP; Carpal tunnel syndrome; Myopathy; Neuromuscular ultrasound; Peripheral neuropathy; Ulnar neuropathy.

Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Cross-sectional (a) and longitudinal (b) views of a normal median nerve (MN). Note the “honey-comb” appearance of the cross-sectional view and the surrounding hyperechoic epineurium seen in both views.
Fig. 2
Fig. 2
Cross-sections of the median nerve (MN) and underlying flexor tendons (ft). When the transducer is angled, the median nerve remains similar in echogenicity whereas the flexor tendons demonstrate the principle of anisotropy as their appearance changes depending on the angle of the transducer (a and b). Similarly, a cross-section of tibialis anterior muscle demonstrates alternating echogenicity with tilting of the transducer in the two sections of muscle separated by an aponeurosis (c and d). Hypoechoic bone shadow is seen on the bottom left corners (B).
Fig. 3
Fig. 3
Cross-sectional views of a normal median nerve (asterisk) at the wrist (a) compared to a hypoechoic, flattened, enlarged median nerve in a patient with carpal tunnel syndrome, with a CSA measuring 17 mm2 (b). Common anatomical variants include bifid median nerve (MN) (c) and a persistent median artery (PMA), seen by doppler (d).
Fig. 4
Fig. 4
A cross-sectional view of a normal median nerve (MN) when imaged at the distal wrist crease, lying above the flexor digitorum tendons (ft) in the carpal tunnel (a). For evaluation of carpal tunnel, the CSA at the wrist should be compared to the CSA in the mid-forearm (b).
Fig. 5
Fig. 5
Cross-sectional views of the ulnar nerve (UN) at the wrist (a), forearm (b), cubital tunnel (d), and epicondylar groove (d). UA: ulnar artery, P: pisiform bone, FDS: flexor digitorum superficialis muscle, FCU: flexor carpi ulnaris muscle, FDP: flexor digitorum profundus muscle. Demonstration of patient positioning for evaluation of the ulnar nerve at the elbow (e).
Fig. 6
Fig. 6
Cross-sectional views of the radial nerve (RN) above the elbow (a) and at the bifurcation into the deep branch of the radial nerve (D) and superficial branch of the radial nerve (S). MeHT: medial head of the triceps brachii, LoHT: long head of the triceps brachii, LaHT: lateral head of the triceps brachii.
Fig. 7
Fig. 7
Cross-sectional (a) and longitudinal (b) views of the fibular nerve (PN) just above the fibular head. Probe placement for the cross-sectional view at the fibular head is demonstrated on the top left corner.
Fig. 8
Fig. 8
Cross-sectional view of the plantar nerves (PTN) within the tarsal tunnel. PTT: posterior tibial tendon, FDL: flexor digitorum longus tendon, PTA: posterior tibial artery, Medial Mall: medial malleolus, FHL: Flexor hallucis longus.
Fig. 9
Fig. 9
Cross-sectional view of the radial nerve (RN) at the level of the mid-humerus in a patient with radial nerve palsy following a comminuted fracture of the humerus. The radial nerve here is focally enlarged (21 mm2) and surrounded by fibrosis.
Fig. 10
Fig. 10
View of the common carotid artery (CCA), internal jugular vein (IJV), and vagus nerve (arrow) beneath the sternocleidomastoid (SCM) (a). Confirmation of vessel location by doppler is demonstrated in the bottom left corner (b).
Fig. 11
Fig. 11
The C5 nerve arises from anterior (AT) and posterior (PT) tubercles that resemble a molar tooth (a). The C6 nerve root arises from a prominent anterior tubercle, resembling a “thumbs up” sign (b). C7 transverse process lacks an anterior tubercle but has a posterior tubercle that resembles the back of a chair (c). The nerve roots can be seen exiting their foramina in a sagittal view (d). The transducer positioning is demonstrated by the black line. The roots and proximal trunks can be seen between the anterior and middle scalene muscles (e). Further laterally, the plexus appears as a “bunch of grapes” (f). SCM: sternocleidomastoid muscle, CA: carotid artery, AS: anterior scalene muscle, MS: middle scalene muscle, SA: subclavian artery.
Fig. 12
Fig. 12
Cross-sectional (a) and longitudinal (b) views of a normal tibialis anterior muscle.
Fig. 13
Fig. 13
Normal increase in diaphragm thickness (double-headed arrows) from expiration (a) to inspiration (b). Ext. Intercostal m.: External intercostal muscle, Int. Intercostal m.: Internal intercostal muscle.
Fig. 14
Fig. 14
The lateral cutaneous nerve of the thigh (N) passing under the inguinal ligament (IL) and above the iliacus at the level of the anterior superior iliac spine (ASIS).

References

    1. Alrajeh M., Preston D.C. Neuromuscular ultrasound in electrically non-localizable ulnar neuropathy. Muscle Nerve. 2018;58:655–659.
    1. Alter K.E., Karp B., Hallett M., Lungu C. Demos Medical Publishing; New York, NY: 2013. Ultrasound-Guided Chemodenervation Procedures: Text and Atlas.
    1. Arts I.M.P., Overeem S., Pillen S., Jurgen Schelhaas H., Zwarts M.J. Muscle changes in amyotrophic lateral sclerosis: a longitudinal ultrasonography study. Clin. Neurophysiol. 2011;122:623–628.
    1. Arts I.M.P., Overeem S., Pillen S., Kleine B.U., Boekestein W.A., Zwarts M.J., Jurgen Schelhaas H. Muscle ultrasonography: a diagnostic tool for amyotrophic lateral sclerosis. Clin. Neurophysiol. 2012;123:1662–1667.
    1. Bartels R.H.M.A., Meulstee J., Verhagen W.I.M., Luttikhuis T.T.M.C.-O. Ultrasound imaging of the ulnar nerve: correlation of preoperative and intraoperative dimensions. Clin. Neurol. Neurosurg. 2008;110:687–690.
    1. Baute V., Strakowski J.A., Reynolds J.W., Karvelas K.R., Ehlers P., Brenzy K.J., Li Z.J., Cartwright M.S. Neuromuscular ultrasound of the brachial plexus: A standardized approach. Muscle Nerve. 2018;58:618–624.
    1. Bayrak I.K., Bayrak A.O., Kale M., Turker H., Diren B. Bifid median nerve in patients with carpal tunnel syndrome. J. Ultrasound Med. 2008;27:1129–1136.
    1. Beekman R., Visser L.H., Verhagen W.I. Ultrasonography in ulnar neuropathy at the elbow: a critical review. Muscle Nerve. 2011;43:627–635.
    1. Bhansing K.J., Van Rosmalen M.H., Van Engelen B.G., Vonk M.C., Van Riel P.L., Pillen S. Increased fascial thickness of the deltoid muscle in dermatomyositis and polymyositis: An ultrasound study. Muscle Nerve. 2015;52:534–539.
    1. Billakota S., Hobson-Webb L.D. Standard median nerve ultrasound in carpal tunnel syndrome: A retrospective review of 1021 cases. Clin. Neurophysiol. Pract. 2017;2:188–191.
    1. Bland J.D.P., Rudolfer S.M. Ultrasound imaging of the median nerve as a prognostic factor for carpal tunnel decompression. Muscle Nerve. 2014;49:741–744.
    1. Bönnemann C.G., Brockmann K., Hanefeld F. Muscle ultrasound in Bethlem myopathy. Neuropediatrics. 2003;34:335–336.
    1. Boon A.J., Harper C.J., Ghahfarokhi L.S., Strommen J.A., Watson J.C., Sorenson E.J. Two-dimensional ultrasound imaging of the diaphragm: quantitative values in normal subjects. Muscle Nerve. 2013;47:884–889.
    1. Boon A.J., O′Gorman C. Ultrasound in the Assessment of Respiration. J. Clin. Neurophysiol. 2016;33:112–119.
    1. Boon A.J., Sekiguchi H., Harper C.J., Strommen J.A., Ghahfarokhi L.S., Watson J.C., Sorenson E.J. Sensitivity and specificity of diagnostic ultrasound in the diagnosis of phrenic neuropathy. Neurology. 2014;83:1264–1270.
    1. Brandsma R., Verbeek R.J., Maurits N.M., van der Hoeven J.H., Brouwer O.F., den Dunnen W.F.A., Burger H., Sival D.A. Visual screening of muscle ultrasound images in children. Ultrasound Med. Biol. 2014;40:2345–2351.
    1. Breiner A., Qrimli M., Ebadi H., Alabdali M., Lovblom L.E., Abraham A., Albulahi H., Perkins B.A., Bril V. Peripheral nerve high-resolution ultrasound in diabetes. Muscle Nerve. 2017;55:171–178.
    1. Cartwright M.S., Passmore L.V., Yoon J.-S., Brown M.E., Caress J.B., Walker F.O. Cross-sectional area reference values for nerve ultrasonography. Muscle Nerve. 2008;37:566–571.
    1. Cartwright M.S., Walker F.O., Griffin L.P., Caress J.B. Peripheral nerve and muscle ultrasound in amyotrophic lateral sclerosis. Muscle Nerve. 2011;44:346–351.
    1. Cartwright M.S., White D.L., Demar S., Wiesler E.R., Sarlikiotis T., Chloros G.D., Yoon J.S., Won S.J., Molnar J.A., Defranzo A.J., Walker F.O. Median nerve changes following steroid injection for carpal tunnel syndrome. Muscle Nerve. 2011;44:25–29.
    1. Chang W.K., Li Y.P., Zhang D.F., Liang B.S. The cubital tunnel syndrome caused by the intraneural or extraneural ganglion cysts: Case report and review of the literature. J. Plast. Reconstr. Aesthet. Surg. 2017;70:1404–1408.
    1. Dekelver I., Van Glabbeek F., Dijs H., Stassijns G. Bilateral ulnar nerve entrapment by the M. anconeus epitrochlearis. A case report and literature review. Clin. Rheumatol. 2012;31:1139–1142.
    1. Demondion X., Herbinet P., Boutry N., Fontaine C., Francke J.-P., Cotten A. Sonographic Mapping of the Normal Brachial Plexus. Am. J. Neuroradiol. 2003;24:1303–1309.
    1. Dietz A.R., Bucelli R.C., Pestronk A., Zaidman C.M. Nerve ultrasound identifies abnormalities in the posterior interosseous nerve in patients with proximal radial neuropathies. Muscle Nerve. 2016;53:379–383.
    1. Dikici A.S., Ustabasioglu F.E., Delil S., Nalbantoglu M., Korkmaz B., Bakan S., Kula O., Uzun N., Mihmanli I., Kantarci F. Evaluation of the tibial nerve with shear-wave elastography: a potential sonographic method for the diagnosis of diabetic peripheral neuropathy. Radiology. 2017;282:494–501.
    1. Elsaidi G.A., Wiesler E.R. Lipofibromatous hamartoma of the median nerve: case presentation of MRI, ultrasound, electrodiagnostic, histologic, and surgical findings. Am. J. Orthop. Belle Mead NJ. 2004;33:514–516.
    1. Fantino O. Role of ultrasound in posteromedial tarsal tunnel syndrome: 81 cases. J. Ultrasound. 2014;17:99–112.
    1. Filippou G., Mondelli M., Greco G., Bertoldi I., Frediani B., Galeazzi M., Giannini F. Ulnar neuropathy at the elbow: how frequent is the idiopathic form? An ultrasonographic study in a cohort of patients. Clin. Exp. Rheumatol. 2010;28:63–67.
    1. Fowler J.R., Munsch M., Tosti R., Hagberg W.C., Imbriglia J.E. Comparison of ultrasound and electrodiagnostic testing for diagnosis of carpal tunnel syndrome: study using a validated clinical tool as the reference standard. J. Bone Jt. Surg. 2014;96
    1. Frijlink D.W., Brekelmans G.J.F., Visser L.H. Increased nerve vascularization detected by color Doppler sonography in patients with ulnar neuropathy at the elbow indicates axonal damage. Muscle Nerve. 2013;47:188–193.
    1. American Association of Neuromuscular & Electrodiagnostic Medicine [WWW Document], n.d. (accessed 3.10.19).
    1. Goedee H.S., Jongbloed B.A., van Asseldonk J.-T.H., Hendrikse J., Vrancken A.F.J.E., Franssen H., Nikolakopoulos S., Visser L.H., van der Pol W.L., van den Berg L.H. A comparative study of brachial plexus sonography and magnetic resonance imaging in chronic inflammatory demyelinating neuropathy and multifocal motor neuropathy. Eur. J. Neurol. 2017;24:1307–1313.
    1. González Pérez I., Corella Montoya F., Casado Fariñas I. Intraneural microcystic lymphatic malformation of the ulnar nerve at the Guyon canal: Unusual cause of ulnar pain in a child. Orthop. Traumatol. Surg. Res. OTSR. 2017;103:513–515.
    1. Granata G., Pazzaglia C., Calandro P., Luigetti M., Martinoli C., Sabatelli M., Padua L. Ultrasound visualization of nerve morphological alteration at the site of conduction block. Muscle Nerve. 2009;40:1068–1070.
    1. Grant T.H., Omar I.M., Dumanian G.A., Pomeranz C.B., Lewis V.A. Sonographic evaluation of common peroneal neuropathy in patients with foot drop. J. Ultrasound Med. 2015;34:705–711.
    1. Grimm A., Décard B.F., Bischof A., Axer H. Ultrasound of the peripheral nerves in systemic vasculitic neuropathies. J. Neurol. Sci. 2014;347:44–49.
    1. Grimm A., Rattay T.W., Winter N., Axer H. Peripheral nerve ultrasound scoring systems: benchmarking and comparative analysis. J. Neurol. 2017;264:243–253.
    1. Heckmatt J.Z., Leeman S., Dubowitz V. Ultrasound imaging in the diagnosis of muscle disease. J. Pediatr. 1982;101:656–660.
    1. Heckmatt J.Z., Pier N., Dubowitz V. Real-time ultrasound imaging of muscles. Muscle Nerve. 1988;11:56–65.
    1. Hobson-Webb L.D., Juel V.C. Common entrapment neuropathies. Continuum. 2017;23:487–511.
    1. Hobson-Webb L.D., Massey J.M., Juel V.C., Sanders D.B. The ultrasonographic wrist-to-forearm median nerve area ratio in carpal tunnel syndrome. Clin. Neurophysiol. 2008;119:1353–1357.
    1. Hobson-Webb L.D., Walker F.O. Traumatic neuroma diagnosed by ultrasonography. Arch. Neurol. 2004;61:1322–1323.
    1. Hwang H.-E., Hsu T.-R., Lee Y.-H., Wang H.-K., Chiou H.-J., Niu D.-M. Muscle ultrasound: A useful tool in newborn screening for infantile onset pompe disease. Medicine (Baltimore) 2017;96
    1. Jacobson J. third ed. Elsevier; Philadelphia, PA: 2017. Fundamentals of Musculoskeletal Ultrasound.
    1. Jansen M., van Alfen N., Nijhuis van der Sanden M.W.G., van Dijk J.P., Pillen S., de Groot I.J.M. Quantitative muscle ultrasound is a promising longitudinal follow-up tool in Duchenne muscular dystrophy. Neuromuscul. Disord. 2012;22:306–317.
    1. Johansson M.T., Ellegaard H.R., Tankisi H., Fuglsang-Frederiksen A., Qerama E. Fasciculations in nerve and muscle disorders – A prospective study of muscle ultrasound compared to electromyography. Clin. Neurophysiol. 2017;128:2250–2257.
    1. Karvelas K.R., Hommel A.L., Cartwright M.S., Walker F.O., Hobson-Webb L.D. Sonographic similarities of inclusion body myositis and myotonic dystrophy. Muscle Nerve. 2018;58:E25–E26.
    1. Kele H., Verheggen R., Reimers C.D. Carpal tunnel syndrome caused by thrombosis of the median artery: the importance of high-resolution ultrasonography for diagnosis. Case report. J. Neurosurg. 2002;97:471–473.
    1. Kerasnoudis A., Pitarokoili K., Behrendt V., Gold R., Yoon M.-S. Bochum ultrasound score versus clinical and electrophysiological parameters in distinguishing acute-onset chronic from acute inflammatory demyelinating polyneuropathy. Muscle Nerve. 2015;51:846–852.
    1. Kerasnoudis A., Pitarokoili K., Gold R., Yoon M.-S. Nerve ultrasound and electrophysiology for therapy monitoring in chronic inflammatory demyelinating polyneuropathy. J. Neuroimaging. 2015;25:931–939.
    1. Lee H., Brekelmans G.J.F., Visser L.H. Quantitative assessment of nerve echogenicity as an additional tool for evaluation of common fibular neuropathy. Clin. Neurophysiol. 2016;127:874–879.
    1. Leis A.A., Smith B.E., Kosiorek H.E., Omejec G., Podnar S. Complete dislocation of the ulnar nerve at the elbow: a protective effect against neuropathy? Muscle Nerve. 2017;56:242–246.
    1. Liu M.-T., Lee J.-T., Wang C.-H., Lin Y.-C., Chou C.-H. Cubital tunnel syndrome caused by ulnar nerve schwannoma in a patient with diabetic sensorimotor polyneuropathy. Acta Neurol. Taiwan. 2016;25:60–64.
    1. Lugão H.B., Frade M.A.C., Mazzer N., Foss N.T., Nogueira-Barbosa M.H. Leprosy with ulnar nerve abscess: ultrasound findings in a child. Skeletal Radiol. 2017;46:137–140.
    1. Mallouhi A., Pülzl P., Pültzl P., Trieb T., Piza H., Bodner G. Predictors of carpal tunnel syndrome: accuracy of gray-scale and color Doppler sonography. Am. J. Roentgenol. 2006;186:1240–1245.
    1. Martínez-Payá J.J., Del Baño-Aledo M.E., Ríos-Díaz J., Tembl-Ferrairó J.I., Vázquez-Costa J.F., Medina-Mirapeix F. Muscular echovariation: a new biomarker in amyotrophic lateral sclerosis. Ultrasound Med. Biol. 2017;43:1153–1162.
    1. Martinoli C., Derchi L.E., Bertolotto M., Gandolfo N., Bianchi S., Fiallo P., Nunzi E. US and MR imaging of peripheral nerves in leprosy. Skeletal Radiol. 2000;29:142–150.
    1. Meng C., Adler R., Peterson M., Kagen L. Combined use of power Doppler and gray-scale sonography: a new technique for the assessment of inflammatory myopathy. J. Rheumatol. 2001;28:1271–1282.
    1. Mhoon J.T., Juel V.C., Hobson-Webb L.D. Median nerve ultrasound as a screening tool in carpal tunnel syndrome: correlation of cross-sectional area measures with electrodiagnostic abnormality. Muscle Nerve. 2012;46:871–878.
    1. Misawa S., Noto Y., Shibuya K., Isose S., Sekiguchi Y., Nasu S., Kuwabara S. Ultrasonographic detection of fasciculations markedly increases diagnostic sensitivity of ALS. Neurology. 2011;77:1532–1537.
    1. Mittal G.A., Wadhwani R., Shroff M., Sukthankar R., Pathan E., Joshi V.R. Ultrasonography in the diagnosis and follow-up of idiopathic inflammatory myopathies–a preliminary study. J. Assoc. Phys. India. 2003;51:252–256.
    1. Nakamichi K., Tachibana S. Restricted motion of the median nerve in carpal tunnel syndrome. J. Hand Surg. 1995;20:460–464.
    1. Nodera H., Takamatsu N., Shimatani Y., Mori A., Sato K., Oda M., Terasawa Y., Izumi Y., Kaji R. Thinning of cervical nerve roots and peripheral nerves in ALS as measured by sonography. Clin. Neurophysiol. 2014;125:1906–1911.
    1. Noto Y.-I., Shiga K., Tsuji Y., Kondo M., Tokuda T., Mizuno T., Nakagawa M. Contrasting echogenicity in flexor digitorum profundus-flexor carpi ulnaris: a diagnostic ultrasound pattern in sporadic inclusion body myositis. Muscle Nerve. 2014;49:745–748.
    1. O’brien T.G., Cazares Gonzalez M.L., Ghosh P.S., Mandrekar J., Boon A.J. Reliability of a novel ultrasound system for gray-scale analysis of muscle. Muscle Nerve. 2017;56:408–412.
    1. O’Gorman C.M., O’brien T.G., Boon A.J. Utility of diaphragm ultrasound in myopathy. Muscle Nerve. 2017;55:427–429.
    1. O’gorman C.M., Weikamp J.G., Baria M., Van Den Engel-Hoek L., Kassardjian C., Van Alfen N., Boon A.J. Detecting fasciculations in cranial nerve innervated muscles with ultrasound in amyotrophic lateral sclerosis. Muscle Nerve. 2017;56:1072–1076.
    1. Omejec G., Podnar S. What causes ulnar neuropathy at the elbow? Clin. Neurophysiol. 2016;127:919–924.
    1. Omejec G., Podnar S. Precise localization of ulnar neuropathy at the elbow. Clin. Neurophysiol. 2015;126:2390–2396.
    1. Padua L., Di Pasquale A., Liotta G., Granata G., Pazzaglia C., Erra C., Briani C., Coraci D., De Franco P., Antonini G., Martinoli C. Ultrasound as a useful tool in the diagnosis and management of traumatic nerve lesions. Clin. Neurophysiol. 2013;124:1237–1243.
    1. Padua L., Liotta G., Di Pasquale A., Granata G., Pazzaglia C., Caliandro P., Martinoli C. Contribution of ultrasound in the assessment of nerve diseases. Eur. J. Neurol. 2012;19:47–54.
    1. Park B.J., Joeng E.S., Choi J.K., Kang S., Yoon J.S., Yang S.N. Ultrasound-guided lateral femoral cutaneous nerve conduction study. Ann. Rehabil. Med. 2015;39:47–51.
    1. Pelosi L., Tse D.M.Y., Mulroy E., Chancellor A.M., Boland M.R. Ulnar neuropathy with abnormal non-localizing electrophysiology: Clinical, electrophysiological and ultrasound findings. Clin. Neurophysiol. 2018;129:2155–2161.
    1. Pigula-Tresansky A.J., Wu J.S., Kapur K., Darras B.T., Rutkove S.B., Anthony B.W. Muscle compression improves reliability of ultrasound echo intensity. Muscle Nerve. 2018;57:423–429.
    1. Pillen S., Arts I.M.P., Zwarts M.J. Muscle ultrasound in neuromuscular disorders. Muscle Nerve. 2008;37:679–693.
    1. Pillen S., Morava E., Van Keimpema M., Ter Laak H.J., De Vries M.C., Rodenburg R.J., Zwarts M.J. Skeletal muscle ultrasonography in children with a dysfunction in the oxidative phosphorylation system. Neuropediatrics. 2006;37:142–147.
    1. Pillen S., van Dijk J.P., Weijers G., Raijmann W., de Korte C.L., Zwarts M.J. Quantitative gray-scale analysis in skeletal muscle ultrasound: a comparison study of two ultrasound devices. Muscle Nerve. 2009;39:781–786.
    1. Pillen Sigrid, van Keimpema M., Nievelstein R.A.J., Verrips A., van Kruijsbergen-Raijmann W., Zwarts M.J. Skeletal muscle ultrasonography: Visual versus quantitative evaluation. Ultrasound Med. Biol. 2006;32:1315–1321.
    1. Pillen S., Verrips A., van Alfen N., Arts I.M.P., Sie L.T.L., Zwarts M.J. Quantitative skeletal muscle ultrasound: diagnostic value in childhood neuromuscular disease. Neuromuscul. Disord. 2007;17:509–516.
    1. Pinto S., Alves P., Pimentel B., Swash M., de Carvalho M. Ultrasound for assessment of diaphragm in ALS. Clin. Neurophysiol. 2016;127:892–897.
    1. Poage C., Roth C., Scott B. Peroneal Nerve Palsy: Evaluation and Management. J. Am. Acad. Orthop. Surg. 2016;24:1–10.
    1. Reimers C.D., Fleckenstein J.L., Witt T.N., Müller-Felber W., Pongratz D.E. Muscular ultrasound in idiopathic inflammatory myopathies of adults. J. Neurol. Sci. 1993;116:82–92.
    1. Ríos-Díaz J., Del Baño-Aledo M.E., Tembl-Ferrairó J.I., Chumillas M.J., Vázquez-Costa J.F., Martínez-Payá J.J. Quantitative neuromuscular ultrasound analysis as biomarkers in amyotrophic lateral sclerosis. Eur. Radiol. 2019
    1. Samarawickrama D., Therimadasamy A.K., Chan Y.C., Vijayan J., Wilder-Smith E.P. Nerve ultrasound in electrophysiologically verified tarsal tunnel syndrome. Muscle Nerve. 2016;53:906–912.
    1. Sanchez J.E., Conkling N., Labropoulos N. Compression syndromes of the popliteal neurovascular bundle due to Baker cyst. J. Vasc. Surg. 2011;54:1821–1829.
    1. Scheidl E., Böhm J., Simó M., Bereznai B., Bereczki D., Arányi Z. Different patterns of nerve enlargement in polyneuropathy subtypes as detected by ultrasonography. Ultrasound Med. Biol. 2014;40:1138–1145.
    1. Scheidl E., Böhm J., Simó M., Rózsa C., Bereznai B., Kovács T., Arányi Z. Ultrasonography of MADSAM neuropathy: focal nerve enlargements at sites of existing and resolved conduction blocks. Neuromuscul. Disord. 2012;22:627–631.
    1. Scholten R.R., Pillen S., Verrips A., Zwarts M.J. Quantitative ultrasonography of skeletal muscles in children: normal values. Muscle Nerve. 2003;27:693–698.
    1. Schreiber S., Abdulla S., Debska-Vielhaber G., Machts J., Dannhardt-Stieger V., Feistner H., Oldag A., Goertler M., Petri S., Kollewe K., Kropf S., Schreiber F., Heinze H.-J., Dengler R., Nestor P.J., Vielhaber S. Peripheral nerve ultrasound in amyotrophic lateral sclerosis phenotypes. Muscle Nerve. 2015;51:669–675.
    1. Schreiber S., Oldag A., Kornblum C., Kollewe K., Kropf S., Schoenfeld A., Feistner H., Jakubiczka S., Kunz W.S., Scherlach C., Tempelmann C., Mawrin C., Dengler R., Schreiber F., Goertler M., Vielhaber S. Sonography of the median nerve in CMT1A, CMT2A, CMTX, and HNPP. Muscle Nerve. 2013;47:385–395.
    1. Simon N.G. Treatment of ulnar neuropathy at the elbow - An ongoing conundrum. Clin. Neurophysiol. 2018;129:1716–1717.
    1. Sivak W.N., Hagerty S.E., Huyhn L., Jordan A.C., Munin M.C., Spiess A.M. Diagnosis of ulnar nerve entrapment at the arcade of struthers with electromyography and ultrasound. Plast. Reconstr. Surg. Glob. Open. 2016;4
    1. Smidt M.H., Visser L.H. Carpal tunnel syndrome: clinical and sonographic follow-up after surgery. Muscle Nerve. 2008;38:987–991.
    1. Smith E.C., Xixis K.I., Grant G.A., Grant S.A. Assessment of obstetric brachial plexus injury with preoperative ultrasound. Muscle Nerve. 2016;53:946–950.
    1. Soni N.J., Franco-Sadud R., Schnobrich D., Dancel R., Tierney D.M., Salame G., Restrepo M.I., McHardy P. Ultrasound guidance for lumbar puncture. Neurol. Clin. Pract. 2016;6:358–368.
    1. Sousa Neves J., Santos Faria D., Cerqueira M., Afonso M.C., Teixeira F. Relevance of ultrasonography in assessing disease activity in patients with idiopathic inflammatory myopathies. Int. J. Rheum. Dis. 2018;21:233–239.
    1. Stewart J.D. The variable clinical manifestations of ulnar neuropathies at the elbow. J. Neurol. Neurosurg. Psychiatry. 1987;50:252–258.
    1. Tagliafico A., Altafini L., Garello I., Marchetti A., Gennaro S., Martinoli C. Traumatic neuropathies: spectrum of imaging findings and postoperative assessment. Semin. Musculoskelet. Radiol. 2010;14:512–522.
    1. Tai T.-W., Wu C.-Y., Su F.-C., Chern T.-C., Jou I.-M. Ultrasonography for diagnosing carpal tunnel syndrome: a meta-analysis of diagnostic test accuracy. Ultrasound Med. Biol. 2012;38:1121–1128.
    1. Tawfik E.A., El Zohiery A.K., Abouelela A.A.K. Proposed sonographic criteria for the diagnosis of idiopathic tarsal tunnel syndrome. Arch. Phys. Med. Rehabil. 2016;97:1093–1099.
    1. Telleman J.A., Grimm A., Goedee S., Visser L.H., Zaidman C.M. Nerve ultrasound in polyneuropathies. Muscle Nerve. 2018;57:716–728.
    1. Tsuji Y., Noto Y.-I., Shiga K., Teramukai S., Nakagawa M., Mizuno T. A muscle ultrasound score in the diagnosis of amyotrophic lateral sclerosis. Clin. Neurophysiol. 2017;128:1069–1074.
    1. van Alfen N., Nienhuis M., Zwarts M.J., Pillen S. Detection of fibrillations using muscle ultrasound: diagnostic accuracy and identification of pitfalls. Muscle Nerve. 2011;43:178–182.
    1. Van Den Engel-Hoek L., Van Alfen N., De Swart B.J.M., De Groot I.J.M., Pillen S. Quantitative ultrasound of the tongue and submental muscles in children and young adults. Muscle Nerve. 2012;46:31–37.
    1. Vanderpool D.W., Chalmers J., Lamb D.W., Whiston T.B. Peripheral compression lesions of the ulnar nerve. J. Bone Joint Surg. Br. 1968;50:792–803.
    1. Vill K., Schessl J., Teusch V., Schroeder S., Blaschek A., Schoser B., Müller-Felber W. Muscle ultrasound in classic infantile and adult Pompe disease: a useful screening tool in adults but not in infants. Neuromuscul. Disord. 2015;25:120–126.
    1. Visser L.H. High-resolution sonography of the common peroneal nerve: detection of intraneural ganglia. Neurology. 2006;67:1473–1475.
    1. Vögelin E., Nüesch E., Jüni P., Reichenbach S., Eser P., Ziswiler H.-R. Sonographic follow-up of patients with carpal tunnel syndrome undergoing surgical or nonsurgical treatment: prospective cohort study. J. Hand Surg. 2010;35:1401–1409.
    1. Walker F.O., Donofrio P.D., Harpold G.J., Ferrell W.G. Sonographic imaging of muscle contraction and fasciculations: a correlation with electromyography. Muscle Nerve. 1990;13:33–39.
    1. Weber M.-A., Jappe U., Essig M., Krix M., Ittrich C., Huttner H.B., Huttner B.H., Meyding-Lamadé U., Hartmann M., Kauczor H.-U., Delorme S. Contrast-enhanced ultrasound in dermatomyositis- and polymyositis. J. Neurol. 2006;253:1625–1632.
    1. Williams E.H., Rosson G.D., Hagan R.R., Hashemi S.S., Dellon A.L. Soleal sling syndrome (proximal tibial nerve compression): results of surgical decompression. Plast. Reconstr. Surg. 2012;129:454–462.
    1. Williams E.H., Williams C.G., Rosson G.D., Dellon L.A. Anatomic site for proximal tibial nerve compression: a cadaver study. Ann. Plast. Surg. 2009;62:322–325.
    1. Zaidman C.M., Al-Lozi M., Pestronk A. Peripheral nerve size in normals and patients with polyneuropathy: an ultrasound study. Muscle Nerve. 2009;40:960–966.
    1. Zaidman C.M., Harms M.B., Pestronk A. Ultrasound of inherited vs. acquired demyelinating polyneuropathies. J. Neurol. 2013;260:3115–3121.
    1. Zaidman C.M., Holland M.R., Anderson C.C., Pestronk A. Calibrated quantitative ultrasound imaging of skeletal muscle using backscatter analysis. Muscle Nerve. 2008;38:893–898.
    1. Zaidman C.M., Malkus E.C., Connolly A.M. Muscle ultrasound quantifies disease progression over time in infants and young boys with duchenne muscular dystrophy. Muscle Nerve. 2015;52:334–338.
    1. Zaidman C.M., Malkus E.C., Siener C., Florence J., Pestronk A., Al-Lozi M. Qualitative and quantitative skeletal muscle ultrasound in late-onset acid maltase deficiency. Muscle Nerve. 2011;44:418–423.
    1. Zaidman C.M., Pestronk A. Nerve size in chronic inflammatory demyelinating neuropathy varies with disease activity and therapy response over time: a retrospective ultrasound study. Muscle Nerve. 2014;50:733–738.
    1. Zaidman C.M., Seelig M.J., Baker J.C., Mackinnon S.E., Pestronk A. Detection of peripheral nerve pathology: comparison of ultrasound and MRI. Neurology. 2013;80:1634–1640.
    1. Zaidman C.M., van Alfen N. Ultrasound in the Assessment of Myopathic Disorders. J. Clin. Neurophysiol. 2016;33:103–111.
    1. Zaidman C.M., Wu J.S., Kapur K., Pasternak A., Madabusi L., Yim S., Pacheck A., Szelag H., Harrington T., Darras B.T., Rutkove S.B. Quantitative muscle ultrasound detects disease progression in Duchenne muscular dystrophy. Ann. Neurol. 2017;81:633–640.
    1. Zaidman C.M., Wu J.S., Wilder S., Darras B.T., Rutkove S.B. Minimal training is required to reliably perform quantitative ultrasound of muscle. Muscle Nerve. 2014;50:124–128.
    1. Zanette G., Fabrizi G.M., Taioli F., Lauriola M.F., Badari A., Ferrarini M., Cavallaro T., Tamburin S. Nerve ultrasound findings differentiate Charcot-Marie-Tooth disease (CMT) 1A from other demyelinating CMTs. Clin. Neurophysiol. 2018;129:2259–2267.

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