The impact of headache in Europe: principal results of the Eurolight project

Timothy J Steiner, Lars Jacob Stovner, Zaza Katsarava, Jose Miguel Lainez, Christian Lampl, Michel Lantéri-Minet, Daiva Rastenyte, Elena Ruiz de la Torre, Cristina Tassorelli, Jessica Barré, Colette Andrée, Timothy J Steiner, Lars Jacob Stovner, Zaza Katsarava, Jose Miguel Lainez, Christian Lampl, Michel Lantéri-Minet, Daiva Rastenyte, Elena Ruiz de la Torre, Cristina Tassorelli, Jessica Barré, Colette Andrée

Abstract

Background: European data, at least from Western Europe, are relatively good on migraine prevalence but less sound for tension-type headache (TTH) and medication-overuse headache (MOH). Evidence on impact of headache disorders is very limited. Eurolight was a data-gathering exercise primarily to inform health policy in the European Union (EU). This manuscript reports personal impact.

Methods: The study was cross-sectional with modified cluster sampling. Surveys were conducted by structured questionnaire, including diagnostic questions based on ICHD-II and various measures of impact, and are reported from Austria, France, Germany, Italy, Lithuania, Luxembourg, Netherlands, Spain and United Kingdom. Different methods of sampling were used in each. The full methodology is described elsewhere.

Results: Questionnaires were analysed from 8,271 participants (58% female, mean age 43.4 y). Participation-rates, where calculable, varied from 10.6% to 58.8%. Moderate interest-bias was detected. Unadjusted lifetime prevalence of any headache was 91.3%. Gender-adjusted 1-year prevalences were: any headache 78.6%; migraine 35.3%; TTH 38.2%, headache on ≥15 d/mo 7.2%; probable MOH 3.1%. Personal impact was high, and included ictal symptom burden, interictal burden, cumulative burden and impact on others (partners and children). There was a general gradient of probable MOH > migraine > TTH, and most measures indicated higher impact among females. Lost useful time was substantial: 17.7% of males and 28.0% of females with migraine lost >10% of days; 44.7% of males and 53.7% of females with probable MOH lost >20%.

Conclusions: The common headache disorders have very high personal impact in the EU, with important implications for health policy.

Figures

Figure 1
Figure 1
Personal impact of headache assessed by HALT index (days lost in preceding 3 months), by country.

References

    1. World Health Organization. The World Health Report 2001. World Health Organization, Geneva; 2001. .
    1. Stovner LJ, Hagen K, Jensen R, Katsarava Z, Lipton R, Scher A, Steiner T, Zwart JA. The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia. 2007;15:193–210. doi: 10.1111/j.1468-2982.2007.01288.x.
    1. Steiner TJ. Lifting the burden: the global campaign against headache. Lancet Neurol. 2004;15:204–205. doi: 10.1016/S1474-4422(04)00703-3.
    1. Steiner TJ. Lifting The Burden: the global campaign to reduce the burden of headache worldwide. J Headache Pain. 2005;15:373–377. doi: 10.1007/s10194-005-0241-7.
    1. Steiner TJ, Birbeck GL, Jensen R, Katsarava Z, Martelletti P, Stovner LJ. Lifting The Burden: the first 7 years. J Headache Pain. 2010;15:451–455. doi: 10.1007/s10194-010-0264-6.
    1. Steiner TJ, Stovner LJ, Dua T, Birbeck GL, Jensen R, Katsarava Z, Martelletti P, Saxena S. Time to act on headache disorders. J Headache Pain. 2011;15:501–503. doi: 10.1007/s10194-011-0368-7.
    1. World Health Organization and Lifting The Burden. ATLAS of headache disorders and resources in the world 2011. World Health Organization, Geneva; 2011.
    1. Katsarava Z, Kukava M, Mirvelashvili E, Tavadze A, Dzagnidze A, Djibuti M, Steiner TJ. Prevalence of headache disorders in the Republic of Georgia: A population based study. Cephalalgia. 2007;15:699.
    1. Yu S, Liu R, Zhao G, Yang X, Qiao X, Feng J, Fang Y, Cao X, He M, Steiner T. The prevalence and burden of primary headaches in China: a population-based door-to-door survey. Headache. 2012;15:582–591. doi: 10.1111/j.1526-4610.2011.02061.x.
    1. Ayzenberg I, Katsarava Z, Sborowski A, Chernysh M, Osipova V, Tabeeva G, Yakhno N, Steiner TJ. The prevalence of primary headache disorders in Russia: a countrywide survey. Cephalalgia. 2012;15:373–381. doi: 10.1177/0333102412438977.
    1. Rao GN, Kulkarni GB, Gururaj G, Rajesh K, Subbakrishna DK, Steiner TJ, Stovner LJ. The burden of headache disorders in India: methodology and questionnaire validation for a community-based survey in Karnataka State. J Headache Pain. 2012;15:543–550. doi: 10.1007/s10194-012-0474-1.
    1. Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Bahalim AN, Barker-Collo S, Barrero LH, Bartels DH, Basáñez MG, Baxter A, Bell ML, Benjamin EJ, Bennett D. et al.Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;15:2163–2196. doi: 10.1016/S0140-6736(12)61729-2.
    1. Steiner TJ, Stovner LJ, Birbeck GL. Migraine: the seventh disabler. J Headache Pain. 2013;15:1. doi: 10.1186/1129-2377-14-1.
    1. Steiner TJ, Stovner LJ, Birbeck GL. Migraine: the seventh disabler. Headache. 2013;15:227–229. doi: 10.1111/head.12034.
    1. Steiner TJ, Stovner LJ, Birbeck GL. Migraine: the seventh disabler. Cephalalgia. 2013;15:289–290. doi: 10.1177/0333102412473843.
    1. Stovner L, Andrée C. On behalf of the Eurolight Steering Committee. Impact of headache in Europe: a review for the Eurolight project. J Headache Pain. 2008;15:139–146. doi: 10.1007/s10194-008-0038-6.
    1. Stovner LJ, Andrée C. Prevalence of headache in Europe: a review for the Eurolight project. J Headache Pain. 2010;15:289–299. doi: 10.1007/s10194-010-0217-0.
    1. Stovner LJ, Zwart JA, Hagen K, Terwindt G, Pascual J. Epidemiology of headache in Europe. Eur J Neurol. 2006;15:333–345. doi: 10.1111/j.1468-1331.2006.01184.x.
    1. Linde M, Gustavsson A, Stovner LJ, Steiner TJ, Barré J, Katsarava Z, Lainez JM, Lampl C, Lantéri-Minet M, Rastenyte D, Ruiz de la Torre E, Tassorelli C, Andrée C. The cost of headache disorders in Europe: the Eurolight project. Eur J Neurol. 2012;15:703–711. doi: 10.1111/j.1468-1331.2011.03612.x.
    1. Andrée C, Stovner LJ, Steiner TJ, Barré J, Katsarava Z, Lainez JM, Lanteri-Minet M, Mick G, Rastenyte D, Ruiz de la Torre E, Tassorelli C, Vriezen P, Lampl C. The Eurolight project: the impact of primary headache disorders in Europe. Description of methods. J Headache Pain. 2011;15:541–549. doi: 10.1007/s10194-011-0356-y.
    1. Andrée C, Vaillant M, Barré J, Katsarava Z, Lainez JM, Lair ML, Lanteri-Minet M, Lampl C, Steiner TJ, Stovner LJ, Tassorelli C, Sándor PS. Development and validation of the EUROLIGHT questionnaire to evaluate the burden of primary headache disorders in Europe. Cephalalgia. 2010;15:1082–1100. doi: 10.1177/0333102409354323.
    1. Peters M, Bertelote JM, Houchin C, Kandoura T, Steiner TJ. Translation protocols. J Headache Pain. 2007;15:S40–S47.
    1. Steiner TJ, Gururaj G, Andrée C, Katsarava Z, Ayzenberg I, Yu SY, Al Jumah M, Tekle-Haimanot R, Birbeck GL, Herekar A, Linde M, Mbewe E, Manandhar K, Risal A, Jensen R, Queiroz LP, Scher AI, Wang SJ, Stovner LJ. Diagnosis, prevalence estimation and burden measurement in population surveys of headache: presenting the HARDSHIP questionnaire. J Headache Pain. 2014;15:3. doi: 10.1186/1129-2377-15-3.
    1. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders. 2nd Edition. Cephalalgia. 2004;15(suppl 1):1–160.
    1. Khil L, Straube A, Evers S, Berger K. Change in intraindividual ICHD-II headache diagnosis over time: a follow-up of the DMKG headache study. Cephalalgia. 2013;15:25–33. doi: 10.1177/0333102412465203.
    1. Stovner LJ, Al Jumah M, Birbeck GL, Gururaj G, Jensen R, Katsarava Z, Queiroz LP, Scher AI, Tekle-Haimanot R, Wang SJ, Steiner TJ. The methodology of population surveys of headache prevalence, burden and cost: principles and recommendations from the Global Campaign against Headache. J Headache Pain. 2014;15:5. doi: 10.1186/1129-2377-15-5.
    1. Index Mundi. European Union Demographics Profile 2013. 2013. .
    1. Steiner TJ. The HALT and HART indices. J Headache Pain. 2007;15:S22–S25.
    1. Stewart WF, Lipton RB, Kolodner KB, Sawyer J, Lee C, Liberman JN. Validity of the Migraine Disability Assessment (MIDAS) score in comparison to a diary-based measure in a population sample of migraine sufferers. Pain. 2000;15:41–52. doi: 10.1016/S0304-3959(00)00305-5.

Source: PubMed

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