Primary nephrotic syndrome in Arab children

A Y Elzouki, F Amin, O P Jaiswal, A Y Elzouki, F Amin, O P Jaiswal

Abstract

We studied 134 Arab children with primary nephrotic syndrome. The annual incidence was 11.6/100 000 children and the ratio of boys to girls was 1.3:1. Ninety eight per cent were responsive to steroids and the mean age of the children at diagnosis was 5.7 years. On follow up (mean 29.8 months, range 1 month to 11 years) 46% had a frequently relapsing course. Renal biopsy, done in 17 patients with frequently relapsing, steroid-dependent nephrotic syndrome, showed minimal changes in 15 and mesangial proliferative lesions in two. Three of the 129 patients did not respond to steroids; two had focal and segmental sclerosis and the third had mesangial proliferative glomerulonephritis. One patient died.

References

    1. Am J Dis Child. 1968 Dec;116(6):623-32
    1. Kidney Int. 1981 Mar;19(3):454-9
    1. Trans R Soc Trop Med Hyg. 1980;74(1):8-16
    1. Arch Dis Child. 1982 Jul;57(7):544-8
    1. S Afr Med J. 1976 Jan 10;50(2):39-43
    1. Arch Dis Child. 1983 Feb;58(2):106-9
    1. Lancet. 1961 Nov 18;2(7212):1103-10
    1. J Pediatr. 1976 May;88(5):828-30
    1. Lancet. 1970 Jun 27;1(7661):1353-9

Source: PubMed

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