A Randomized Controlled Trial to Increase HIV Testing Demand Among Female Sex Workers in Kenya Through Announcing the Availability of HIV Self-testing Via Text Message

Elizabeth A Kelvin, Gavin George, Eva Mwai, Samuel Kinyanjui, Matthew L Romo, Jacob O Odhiambo, Faith Oruko, Eston Nyaga, Kaymarlin Govender, Joanne E Mantell, Elizabeth A Kelvin, Gavin George, Eva Mwai, Samuel Kinyanjui, Matthew L Romo, Jacob O Odhiambo, Faith Oruko, Eston Nyaga, Kaymarlin Govender, Joanne E Mantell

Abstract

We assessed whether informing female sex workers about the availability of HIV self-testing at clinics in Kenya using text messages would increase HIV testing rates. We selected a sample of 2196 female sex workers registered in an electronic health record system who were irregular HIV testers and randomized them to be sent a text message announcing the availability of (1) HIV self-test kits sent three times (intervention), (2) general HIV testing sent three times (enhanced standard of care [SOC]), or (3) general HIV testing sent one time (traditional SOC). Participants in the intervention arm were significantly more likely to test for HIV during 2-month follow-up compared to those in the enhanced SOC (OR 1.9, p = 0.001). There was no difference in HIV testing between those in the enhanced SOC and the traditional SOC arms. Announcing the availability of HIV self-testing via text message increased HIV testing among this high-risk group.

Keywords: Female sex workers; HIV self-testing; HIV testing; Kenya; Randomized controlled trial.

Conflict of interest statement

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

The study procedures were approved by the City University of New York Institutional Review Board, the Kenya Medical Research Institute Ethics Committee, and the University of KwaZulu-Natal Biomedical Research Ethics Committee.

Informed Consent

We used a passive informed consent process in this study as described in the paper in the section titled “Sample, eligibility and consent.”

Figures

Fig. 1
Fig. 1
Flow of female sex workers participants (consort flowchart)

References

    1. UNAIDS. The gap report 2014: sex workers. 2014; . Accessed 7 Feb 2018.
    1. National AIDS Control Council of Kenya (NASCOP). Kenya AIDS response progress report 2014: progress towards zero. 2014; . Accessed 4 Nov 2017.
    1. Musyoki H, Kellogg TA, Geibel S, et al. Prevalence of HIV, sexually transmitted infections, and risk behaviours among female sex workers in Nairobi, Kenya: results of a respondent driven sampling study. AIDS Behav. 2015;19(Suppl 1):S46–S58. doi: 10.1007/s10461-014-0919-4.
    1. Masters SH, Agot K, Obonyo B, Napierala Mavedzenge S, Maman S, Thirumurthy H. Promoting partner testing and couples testing through secondary distribution of HIV self-tests: a randomized clinical trial. PLoS Med. 2016;13(11):e1002166. doi: 10.1371/journal.pmed.1002166.
    1. Pebody R. Can self-testing engage ‘hard-to-reach’ men with HIV testing? AIDSMap; 2017. . Accessed 13 Sept 2017.
    1. Ortblad K, Kibuuka Musoke D, Ngabirano T, et al. Direct provision versus facility collection of HIV self-tests among female sex workers in Uganda: a cluster-randomized controlled health systems trial. PLoS Med. 2017;14(11):e1002458. doi: 10.1371/journal.pmed.1002458.
    1. Chanda MM, Ortblad KF, Mwale M, et al. HIV self-testing among female sex workers in Zambia: a cluster randomized controlled trial. PLoS Med. 2017;14(11):e1002442. doi: 10.1371/journal.pmed.1002442.
    1. Kelvin E, Mwai E, Romo M, et al. Evaluating oral HIV self-testing to increase HIV testing uptake among truck drivers in Kenya. 3ie Impact Evaluation Report 64; 2017. .
    1. Kelvin EA, George G, Mwai E, et al. Offering self-administered oral HIV testing to truck drivers in Kenya to increase testing: a randomized controlled trial. AIDS Care. 2017;30:47–55. doi: 10.1080/09540121.2017.1360997.
    1. North Star Alliance. Key figures; 2016. . Accessed 19 Dec 2016.
    1. CDC. STD & HIV screening recommendations; 2017. . Accessed 18 Jan 2018.
    1. OraSure Technologies I. OraQuick HIV self-test; 2017. . Accessed 13 Sept 2017.
    1. UNAIDS. Kenya launches self-test kits and PrEP; 2017. . Accessed 11 Sept 2017.
    1. Kenya PSo. HIV self-testing kits FAQ; 2017. . Accessed 8 Sept 2017.
    1. Pew Research Center. Cell phones in Africa: communication lifeline; 2015. . Accessed 13 Sept 2017.
    1. Kelvin EA, George G, Mwai E, et al. Offering self-administered oral HIV testing as a choice to truck drivers in Kenya: predictors of uptake and need for guidance while self-testing. AIDS Behav. 2017;22:580–592. doi: 10.1007/s10461-017-1783-9.
    1. Strauss M, George G, Lansdell E, et al. HIV testing preferences among long distance truck drivers in Kenya: a discrete choice experiment. AIDS Care. 2017;30:72–80. doi: 10.1080/09540121.2017.1367086.
    1. Lippman SA, Lane T, Rabede O, et al. High acceptability and increased HIV testing frequency following introduction of HIV self-testing and network distribution among South African MSM. J Acquir Immune Defic Syndr. 2017;77:279–287. doi: 10.1097/QAI.0000000000001601.
    1. OraQuick. Introducing a majoradvance in the fight against HIV/AIDS: the first in-home oral HIV test; 2018. . Accessed 6 Jun 2018.
    1. WHO. HIV assays operational characteristics HIV rapid diagnostic tests (detection of HIV-1/2 antibodies report 2017; 2017. . Accessed 6 Jun 2018.
    1. CDC. Act against AIDS: testing; 2018. . Accessed 6 Jun 2018.

Source: PubMed

3
Subskrybuj