Successful extraction of refractory thrombus from an ectatic coronary artery using stent retriever during primary angioplasty for acute myocardial infarction: a case report
Kesavamoorthy Bhoopalan, Ravindran Rajendran, Srinivasan Alagarsamy, Niranjana Kesavamoorthy, Kesavamoorthy Bhoopalan, Ravindran Rajendran, Srinivasan Alagarsamy, Niranjana Kesavamoorthy
Abstract
Background: Ectatic coronary segments are nidi for thrombus formation due to altered flow dynamics and stasis-an important component of Virchow's triad. Ectasia accompanied by an adjacent coronary stenosis with or without a plaque event can lead to acute myocardial infarctions complicated by huge thrombus burden.
Case summary: Here, we present a case of a young male with acute inferior wall myocardial infarction complicated by Type IV coronary artery ectasia of the right coronary artery and huge thrombus burden that was refractory to conventional methods of thrombus management like thrombo-suction and intracoronary cocktails including tenecteplase. After a stormy course of transient complete heart block and recurrent ventricular tachycardia, the thrombus was successfully extracted using a stent retriever to achieve thrombolysis in myocardial infarction (TIMI) II plus flow distally. The lesion just distal to the ectasia was stented 24 h later to achieve TIMI III flow and the patient had an uneventful recovery subsequently.
Discussion: Angiographically visible thrombus that is refractory to intracoronary medications and aspiration thrombectomy can be successfully managed using a stent retriever.
Keywords: Case report; Coronary artery ectasia; Solitaire AB; Thrombectomy; Thrombus retrieval.
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References
- Markis JE, Joffe CD, Cohn PF, Feen DJ, Herman MV, Gorlin R.. Clinical significance of coronary arterial ectasia. Am J Cardiol 1976;37:217–222.
- Doi T, Kataoka Y, Noguchi T, Shibata T, Nakashima T, Kawakami S, Nakao K, Fujino M, Nagai T, Kanaya T, Tahara Y, Asaumi Y, Tsuda E, Nakai M, Nishimura K, Anzai T, Kusano K, Shimokawa H, Goto Y, Yasuda S.. Coronary artery ectasia predicts future cardiac events in patients with acute myocardial infarction. Arterioscler Thromb Vasc Biol 2017;37:2350–2355.
- Campanile A, Sozzi FB, Consonni D, Piscione F, Sganzerla P, Indolfi C, Stabile A, Migliorini A, Antoniucci D, Ferraresi R, Boccuzzi G, Danzi GB.. Primary PCI for the treatment of ectatic infarct-related coronary artery. Minerva Cardioangiol 2014;62:327–333.
- Mazhar J, Mashicharan M, Farshid A.. Predictors and outcome of no-reflow post primary percutaneous coronary intervention for ST elevation myocardial infarction. Int J Cardiol Heart Vasc 2015;10:8–12.
- Brunetti ND, Salvemini G, Cuculo A, Ruggiero A, De Gennaro L, Gaglione A, Di Biase M.. Coronary artery ectasia is related to coronary slow flow and inflammatory activation. Atherosclerosis 2014;233:636–640.
- Arnous S, Agelaki M, Shakhshir N, Kelly D, Ordoubadi FF, Mamas MA, Fraser D.. Thrombus capture by withdrawal of an open filter device: a useful treatment for large non-occlusive coronary thrombus. EuroIntervention 2014;10:689–693.
- Uribe CE, Zuñiga M, Madrid C.. Mechanical thrombectomy using the Solitaire stent in a left main coronary artery: a novel approach to coronary thrombus retrieval. Catheter Cardiovasc Interv 2017;89:71–77.
- Silvain J, Collet J-P, Nagaswami C, Beygui F, Edmondson KE, Bellemain-Appaix A, Cayla G, Pena A, Brugier D, Barthelemy O, Montalescot G, Weisel JW.. Composition of coronary thrombus in acute myocardial infarction. J Am Coll Cardiol 2011;57:1359–1367.
- Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, Brown M, Demaerschalk BM, Hoh B, Jauch EC, Kidwell CS, Leslie-Mazwi TM, Ovbiagele B, Scott PA, Sheth KN, Southerland AM, Summers DV, Tirschwell DL; on behalf of the American Heart Association Stroke Council. 2018 Guidelines for the early management of patients with acute ischaemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2018;49:e46–e110.
- Denswil NP, van der Wal AC, Ritz K, de Boer OJ, Aronica E, Troost D, Daemen MJAP.. Atherosclerosis in the circle of Willis: spatial differences in composition and in distribution of plaques. Atherosclerosis 2016;251:78–84.
- Mathur KS, Kashyap SK, Kumar V.. Correlation of the extent and severity of atherosclerosis in the coronary and cerebral arteries. Circulation 1963;27:929–934.
Source: PubMed