Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty
M Khan, J H Kuiper, Christine Sieniawska, J B Richardson, M Khan, J H Kuiper, Christine Sieniawska, J B Richardson
Abstract
Background/aims: Cobalt and chromium are released from MOM hips and their precise nature (ions/particles) is not known. Their distribution in serum, plasma, and whole blood may help to determine their nature.
Methods: We measured cobalt and chromium concentrations in plasma, serum, and whole blood samples of patients with resurfacing MOM hips.
Results: We found that chromium concentration was highest in plasma, followed by serum and whole blood. Chromium and cobalt concentrations were higher in serum and plasma, compared to whole blood.
Conclusion: We, therefore, suggest that in future cobalt and chromium concentrations shall be reported using plasma samples.
Keywords: Chromium; Cobalt; Metal ions; Plasma; Serum.
Figures
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![Fig. 2](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/5103041/bin/gr2.jpg)
![Fig. 3](https://www.ncbi.nlm.nih.gov/pmc/articles/instance/5103041/bin/gr3.jpg)
Source: PubMed