Steroid responsive eosinophilic gastric outlet obstruction in a child

Abstract

Gastric outlet obstruction is a rare complication of eosinophilic gastroenteritis, most commonly treated surgically. We report a case of eosinophilic gastric outlet obstruction in a child that responded to conservative medical management. A brief review of this clinical entity is also provided.

Figures

Figure 1

Upper gastrointestinal image of the patient. Note the minimal advancement of the contrast material through the pylorus (arrow).

Figure 2

Histologic images before and 5 d after steroid therapy. A: Peripyloric antral sections showed prominent eosinophilic infiltration of the lamina propria (up to 30 eosinophils per single high power field), with occasional degranulation (arrow) of eosinophilic content and infiltration of the muscularis mucosae; B: Biopsies 5 d after intravenous steroid therapy demonstrated only a few eosinophils with a peak count of 2 eosinophils per high power field (HE, × 40).