Improvement of the management of mental well-being and empathy in Chinese medical students: a randomized controlled study

Rong Rong, Wei Chen, Zihao Dai, Jingli Gu, Weiying Chen, Yanbin Zhou, Ming Kuang, Haipeng Xiao, Rong Rong, Wei Chen, Zihao Dai, Jingli Gu, Weiying Chen, Yanbin Zhou, Ming Kuang, Haipeng Xiao

Abstract

Background: Among Chinese medical students, there is a high prevalence of mental health-related issues and low empathy. Effective strategies to improve this situation are lacking. This study aims to investigate the efficacy of the intervention courses designed to enhance the mental health and empathy of senior Chinese medical students.

Methods: A total of 146 3rd - and 4th -year medical students were randomized to an intervention group (n = 74) and a control group (n = 72). A pilot study including 5 pre-clinical students and 5 interns was first carried out to determine the themes and content of the intervention courses. The designed courses were delivered in the intervention group once a month three times, while the control group had no specific intervention. Five self-assessment questionnaires, including the General Self-Efficacy (GSE) scale, Medical Outcomes Study Short Form 8 (SF-8), Patient Health Questionnaire-9 (PHQ-9), Maslach Burnout Inventory (MBI), and Jefferson Scale of Empathy-Health Care Provider Student version (JSE-HPS), were completed by the students before and one month after the courses to evaluate their levels of self-efficacy (SE), quality of life (QoL), depression, burnout, and empathy, respectively. Qualitative data were collected via e-mail two years after the intervention.

Results: Compared to the control group, the intervention group showed significantly higher scores for empathy (111.0 [IQR 102.0, 118.0] vs. 106.0 [IQR 93.0, 111.5]; P = .01) and QoL (32.0 [IQR 28.0, 35.0] vs. 29.5 [IQR 26.0, 34.0]; P = .04). The rate of depression was significantly lower in the intervention group than in the control group (13.5 % vs. 29.2 %; chi-square test, P = .02). However, no significant differences in self-efficacy (25.6 ± 4.8 vs. 24.3 ± 6.3; P = .16) or burnout (27.0 % vs. 34.7 %; Chi-square test, P = .31) were observed between the two groups.

Conclusions: The intervention courses had a positive impact on mental well-being and empathy in senior Chinese medical students, which might help provide novel information for their incorporation into the medical school curriculum.

Trial registration: ClinicalTrials.gov Identifier: NCT02645643; Date of registration: 05/01/2016.

Keywords: Depression; Empathy; Medical education; Medical students; Mental health.

Conflict of interest statement

The authors declare that they have no competing interests.

© 2021. The Author(s).

Figures

Fig. 1
Fig. 1
Flowchart of the inclusion of study participants according to CONSORT diagram
Fig. 2
Fig. 2
The scatter plot of (a) median of QoL, b proportion of depression (PHQ-9), and c median of empathy (JSE-HPS) before and after intervention for each group. Red represents data from control group and blue from intervention group. Bars mean 95 % confidence interval

References

    1. Dyrbye LN, Thomas MR, Shanafelt TD. Systematic review of depression, anxiety, and other indicators of psychological distress among U.S. and Canadian medical students. Acad Med. 2006;81(4):354–73. doi: 10.1097/00001888-200604000-00009.
    1. Shiralkar MT, Harris TB, Eddins-folensbee FF, Coverdale JH. A systematic review of stress-management programs for medical students. Acad Psychiatry. 2013;37(3):158–64. doi: 10.1176/appi.ap.12010003.
    1. Yusoff MS, Abdulrahim AF, Yaacob MJ. Prevalence and Sources of Stress among Universiti Sains Malaysia Medical Students. Malays J Med Sci. 2010;17(1):30–7.
    1. Sobowale K, Zhou N, Fan J, Liu N, Sherer R. Depression and suicidal ideation in medical students in China: a call for wellness curricula. Int J Med Educ. 2014;5:31–6. doi: 10.5116/ijme.52e3.a465.
    1. Yusoff MS, Abdulrahim AF, Baba AA, Ismail SB, Matpa MN, Esa AR. Prevalence and associated factors of stress, anxiety and depression among prospective medical students. Asian J Psychiatr. 2013;6(2):128–33. doi: 10.1016/j.ajp.2012.09.012.
    1. Frajerman A, Morvan Y, Krebs MO, Gorwood P, Chaumette B. Burnout in medical students before residency: a systematic review and meta-analysis. Eur Psychiatr. 2019;55:36–42. doi: 10.1016/j.eurpsy.2018.08.006.
    1. Kumar GS, Jain A, Hegde S. Prevalence of depression and its associated factors using Beck Depression Inventory among students of a medical college in Karnataka. Indian J Psychiatr. 2012;54(3):223–6. doi: 10.4103/0019-5545.102412.
    1. Ngasa SN, Sama CB, Dzekem BS, Nforchu KN, Tindong M, Aroke D, Dimala CA. Prevalence and factors associated with depression among medical students in Cameroon: a cross-sectional study. BMC Psychiatry. 2017;17(1):216. doi: 10.1186/s12888-017-1382-3.
    1. Mukhtar F, Oei TP. A review on assessment and treatment for depression in malaysia. Depress Res Treat. 2011;2011:123642.
    1. Smith CK, Peterson DF, Degenhardt BF, Johnson JC. Depression, anxiety, and perceived hassles among entering medical students. Psychol Health Med. 2007;12(1):31–9. doi: 10.1080/13548500500429387.
    1. Mazurkiewicz R, Korenstein D, Fallar R, Ripp J. The prevalence and correlations of medical student burnout in the pre-clinical years: a cross-sectional study. Psychol Health Med. 2012;17(2):188–95. doi: 10.1080/13548506.2011.597770.
    1. Sun J, Liu S, Liu Q, Wang Z, Wang J, Hu CJ, Stuntz M, Ma J, Liu Y. Impact of adverse media reporting on public perceptions of the doctor-patient relationship in China: an analysis with propensity score matching method. BMJ Open. 2018;8(8):e22455. doi: 10.1136/bmjopen-2018-022455.
    1. He AJ, Qian J. Explaining medical disputes in Chinese public hospitals: the doctor-patient relationship and its implications for health policy reforms. Health Econ Policy Law. 2016;11(4):359–78. doi: 10.1017/S1744133116000128.
    1. Jie L. New generations of Chinese doctors face crisis. Lancet. 2012;379(9829):1878. doi: 10.1016/S0140-6736(12)60774-0.
    1. Zeng J, Zeng XX, Tu Q. A gloomy future for medical students in China. Lancet. 2013;382(9908):1878. doi: 10.1016/S0140-6736(13)62624-0.
    1. Wan P, Long E. Expectations of medical students in China. Lancet. 2016;387(10025):1275. doi: 10.1016/S0140-6736(16)30022-8.
    1. Li D, Xu H, Kang M, Ma S. Empathy in Chinese eight-year medical program students: differences by school year, educational stage, and future career preference. BMC Med Educ. 2018;18(1):241. doi: 10.1186/s12909-018-1348-2.
    1. Blatt B, Kallenberg G, Lang F, Mahoney P, Patterson J, Dugan B, Sun S. Found in translation: exporting patient-centered communication and small group teaching skills to China. Med Educ Online. 2009;14:6.
    1. de Vibe M, Solhaug I, Tyssen R, Friborg O, Rosenvinge JH, Sørlie T, Bjørndal A. Mindfulness training for stress management: a randomised controlled study of medical and psychology students. BMC Med Educ. 2013;13:107. doi: 10.1186/1472-6920-13-107.
    1. Kuhlmann SM, Huss M, Bürger A, Hammerle F. Coping with stress in medical students: results of a randomized controlled trial using a mindfulness-based stress prevention training (MediMind) in Germany. BMC Med Educ. 2016;16(1):316. doi: 10.1186/s12909-016-0833-8.
    1. Prasad L, Varrey A, Sisti G. Medical Students’ Stress Levels and Sense of Well Being after Six Weeks of Yoga and Meditation. Evid Based Complement Altern Med. 2016;2016:9251849. doi: 10.1155/2016/9251849.
    1. Thompson D, Goebert D, Takeshita J. A program for reducing depressive symptoms and suicidal ideation in medical students. Acad Med. 2010;85(10):1635–9. doi: 10.1097/ACM.0b013e3181f0b49c.
    1. Li C, Chu F, Wang H, Wang XP. Efficacy of Williams LifeSkills training for improving psychological health: a pilot comparison study of Chinese medical students. Asia Pac Psychiatry. 2014;6(2):161–9. doi: 10.1111/appy.12084.
    1. Lemoine ER, Nassim JS, Rana J, Burgin S. Teaching & Learning Tips 4: Motivation and emotion in learning. Int J Dermatol. 2018;57(2):233–6. doi: 10.1111/ijd.13715.
    1. Kaplan-liss E, Lantz-gefroh V, Bass E, Killebrew D, Ponzio NM, Savi C. O’connell C. Teaching Medical Students to Communicate With Empathy and Clarity Using Improvisation. Acad Med. 2018;93(3):440–3. doi: 10.1097/ACM.0000000000002031.
    1. Yu Pan X, Yang J, He Y, Gu X, Zhan H, Gu Q, Qiao D, Zhou, Huimin Jin To be or not to be a doctor, that is the question: a review of serious incidents of violence against doctors in China from 2003–2013. J Public Health. 2015;23(2):111–6. doi: 10.1007/s10389-015-0658-7.
    1. Wen D, Ma X, Li H, Liu Z, Xian B, Liu Y. Empathy in Chinese medical students: psychometric characteristics and differences by gender and year of medical education. BMC Med Educ. 2013;13:130. doi: 10.1186/1472-6920-13-130.
    1. Quaintance JL, Arnold L, Thompson GS. What students learn about professionalism from faculty stories: an “appreciative inquiry” approach. Acad Med. 2010;85(1):118–23. doi: 10.1097/ACM.0b013e3181c42acd.
    1. Glase BG, Strauss AL. The Discovery of Grounded Theory: Strategies for Qualitative Research. New York: Aldine Publishing Company; 1967.
    1. West CP, Dyrbye LN, Rabatin JT, Call TG, Davidson JH, Multari A, Romanski SA, Hellyer JM, Sloan JA, Shanafelt TD. Intervention to promote physician well-being, job satisfaction, and professionalism: a randomized clinical trial. JAMA Intern Med. 2014;174(4):527–33. doi: 10.1001/jamainternmed.2013.14387.
    1. Warnecke E, Quinn S, Ogden K, Towle N, Nelson MR. A randomised controlled trial of the effects of mindfulness practice on medical student stress levels. Med Educ. 2011;45(4):381–8. doi: 10.1111/j.1365-2923.2010.03877.x.
    1. Ellman MS, Fortin AH, Putnam A, Bia M. Implementing and Evaluating a Four-Year Integrated End-of-Life Care Curriculum for Medical Students. Teach Learn Med. 2016;28(2):229–39. doi: 10.1080/10401334.2016.1146601.
    1. Schwarzer R. Self-efficacy: thought control of action. Washington DC: Hemisphere; 1992.
    1. Turner-bowker DM, Bayliss MS, Ware JE, Kosinski M. Usefulness of the SF-8 Health Survey for comparing the impact of migraine and other conditions. Qual Life Res. 2003;12(8):1003–12. doi: 10.1023/A:1026179517081.
    1. Dyrbye LN, Harper W, Moutier C, Durning SJ, Power DV, Massie FS, Eacker A, Thomas MR, Satele D, Sloan JA, et al. A multi-institutional study exploring the impact of positive mental health on medical students’ professionalism in an era of high burnout. Acad Med. 2012;87(8):1024–31. doi: 10.1097/ACM.0b013e31825cfa35.
    1. Dyrbye LN, Thomas MR, Power DV, Durning S, Moutier C, Massie FS, Harper W, Eacker A, Szydlo DW, Sloan JA, et al. Burnout and serious thoughts of dropping out of medical school: a multi-institutional study. Acad Med. 2010;85(1):94–102. doi: 10.1097/ACM.0b013e3181c46aad.
    1. Thomas NK. Resident burnout. JAMA. 2004;292(23):2880–9. doi: 10.1001/jama.292.23.2880.
    1. Maslach C JSLM. Maslach Burnout Inventory Manual. Palo Alto: Consulting Psychologists Press; 1996.
    1. Chen D, Lew R, Hershman W, Orlander J. A cross-sectional measurement of medical student empathy. J Gen Intern Med. 2007;22(10):1434–8. doi: 10.1007/s11606-007-0298-x.
    1. Song X, Ding N, Jiang N, Li H, Wen D. Time use in out-of-class activities and its association with self-efficacy and perceived stress: data from second-year medical students in China. Med Educ Online. 2020;25(1):1759868. doi: 10.1080/10872981.2020.1759868.
    1. Guo YF, Zhang X, Plummer V, Lam L, Cross W, Zhang JP. Positive psychotherapy for depression and self-efficacy in undergraduate nursing students: a randomized, controlled trial. Int J Mental Health Nurs. 2017;26(4):375–83. doi: 10.1111/inm.12255.
    1. Zhong X, Liu Y, Pu J, Tian L, Gui S, Song X, Xu S, Zhou X, Wang H, Zhou W, et al. Depressive symptoms and quality of life among Chinese medical postgraduates: a national cross-sectional study. Psychol Health Med. 2019;24(8):1015–27. doi: 10.1080/13548506.2019.1626453.
    1. Zhang YL, Liang W, Chen ZM, Zhang HM, Zhang JH, Weng XQ, Yang SC, Zhang L, Shen LJ, Zhang YL. Validity and reliability of Patient Health Questionnaire-9 and Patient Health Questionnaire-2 to screen for depression among college students in China. Asia Pac Psychiatr. 2013;5(4):268–75. doi: 10.1111/appy.12103.
    1. Wang W, Bian Q, Zhao Y, Li X, Wang W, Du J, Zhang G, Zhou Q, Zhao M. Reliability and validity of the Chinese version of the Patient Health Questionnaire (PHQ-9) in the general population. Gen Hosp Psychiatry. 2014;36(5):539–44. doi: 10.1016/j.genhosppsych.2014.05.021.
    1. Wang Q, Wang L, Shi M, Li X, Liu R, Liu J, Zhu M, Wu H. Empathy, burnout, life satisfaction, correlations and associated socio-demographic factors among Chinese undergraduate medical students: an exploratory cross-sectional study. BMC Med Educ. 2019;19(1):341. doi: 10.1186/s12909-019-1788-3.
    1. Chunming WM, Harrison R, Macintyre R, Travaglia J, Balasooriya C. Burnout in medical students: a systematic review of experiences in Chinese medical schools. BMC Med Educ. 2017;17(1):217. doi: 10.1186/s12909-017-1064-3.
    1. Menon V, Sarkar S, Kumar S. Barriers to healthcare seeking among medical students: a cross sectional study from South India. Postgrad Med J. 2015;91(1079):477–82. doi: 10.1136/postgradmedj-2015-133233.
    1. Mcconnell MM, Eva KW. The role of emotion in the learning and transfer of clinical skills and knowledge. Acad Med. 2012;87(10):1316–22. doi: 10.1097/ACM.0b013e3182675af2.
    1. Pan XF, Wen Y, Zhao Y, Hu JM, Li SQ, Zhang SK, Li XY, Chang H, Xue QP, Zhao ZM, et al. Prevalence of depressive symptoms and its correlates among medical students in China: a national survey in 33 universities. Psychol Health Med. 2016;21(7):882–9. doi: 10.1080/13548506.2015.1127395.
    1. Wilkinson TJ, Gill DJ, Fitzjohn J, Palmer CL, Mulder RT. The impact on students of adverse experiences during medical school. Med Teach. 2006;28(2):129–35. doi: 10.1080/01421590600607195.
    1. Brazeau CM, Shanafelt T, Durning SJ, Massie FS, Eacker A, Moutier C, Satele DV, Sloan JA, Dyrbye LN. Distress among matriculating medical students relative to the general population. Acad Med. 2014;89(11):1520–5. doi: 10.1097/ACM.0000000000000482.
    1. Casas RS, Xuan Z, Jackson AH, Stanfield LE, Harvey NC, Chen DC. Associations of medical student empathy with clinical competence. Patient Educ Couns. 2017;100(4):742–7. doi: 10.1016/j.pec.2016.11.006.
    1. Howick J, Moscrop A, Mebius A, Fanshawe TR, Lewith G, Bishop FL, Mistiaen P, Roberts NW, Dieninytė E, Hu XY, et al. Effects of empathic and positive communication in healthcare consultations: a systematic review and meta-analysis. J R Soc Med. 2018;111(7):240–52. doi: 10.1177/0141076818769477.
    1. Flickinger TE, Saha S, Roter D, Korthuis PT, Sharp V, Cohn J, Eggly S, Moore RD, Beach MC. Clinician empathy is associated with differences in patient-clinician communication behaviors and higher medication self-efficacy in HIV care. Patient Educ Couns. 2016;99(2):220–6. doi: 10.1016/j.pec.2015.09.001.
    1. Quince T, Thiemann P, Benson J, Hyde S. Undergraduate medical students’ empathy: current perspectives. Adv Med Educ Pract. 2016;7:443–55. doi: 10.2147/AMEP.S76800.

Source: PubMed

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