The Disease Burden Associated with Overweight and Obesity

Aviva Must, Nicola M McKeown, Kenneth R Feingold, Bradley Anawalt, Marc R Blackman, Alison Boyce, George Chrousos, Emiliano Corpas, Wouter W de Herder, Ketan Dhatariya, Kathleen Dungan, Johannes Hofland, Sanjay Kalra, Gregory Kaltsas, Nitin Kapoor, Christian Koch, Peter Kopp, Márta Korbonits, Christopher S Kovacs, Wendy Kuohung, Blandine Laferrère, Miles Levy, Elizabeth A McGee, Robert McLachlan, Maria New, Jonathan Purnell, Rakesh Sahay, Amy S Shah, Frederick Singer, Mark A Sperling, Constantine A Stratakis, Dace L Trence, Don P Wilson, Aviva Must, Nicola M McKeown, Kenneth R Feingold, Bradley Anawalt, Marc R Blackman, Alison Boyce, George Chrousos, Emiliano Corpas, Wouter W de Herder, Ketan Dhatariya, Kathleen Dungan, Johannes Hofland, Sanjay Kalra, Gregory Kaltsas, Nitin Kapoor, Christian Koch, Peter Kopp, Márta Korbonits, Christopher S Kovacs, Wendy Kuohung, Blandine Laferrère, Miles Levy, Elizabeth A McGee, Robert McLachlan, Maria New, Jonathan Purnell, Rakesh Sahay, Amy S Shah, Frederick Singer, Mark A Sperling, Constantine A Stratakis, Dace L Trence, Don P Wilson

Excerpt

Many epidemiological studies have considered the impact of increasing body weight, body mass index (BMI), and other anthropometric measurements on the risk of chronic disease (1, 2), including coronary heart disease (CHD), type 2 diabetes mellitus (T2DM), hypertension, stroke, and cancers of the breast, endometrium, and colon (3, 4).

Because body fat distribution is linked to obesity and is of particular importance in the etiology of certain chronic diseases, this chapter provides the reader with an overview of the epidemiological evidence linking both excess body weight and body fat distribution to the risk of several chronic diseases in adults. This chapter complements Chapter 1, in which the indicators of obesity are covered in detail, and Chapter 13, which provides a full discussion of the pathophysiology of obesity-related health conditions.

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Source: PubMed

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