Self-reported short sleep duration and frequent snoring in pregnancy: impact on glucose metabolism

Francesca L Facco, William A Grobman, Jamie Kramer, Kim H Ho, Phyllis C Zee, Francesca L Facco, William A Grobman, Jamie Kramer, Kim H Ho, Phyllis C Zee

Abstract

Objective: We sought to evaluate the impact of short sleep duration (SSD) and frequent snoring (FS) on glucose metabolism during pregnancy.

Study design: We conducted a prospective cohort study of healthy nulliparas who participated in a sleep survey study. SSD was defined as <7 hours of sleep per night and FS, as snoring >or=3 nights per week. Outcomes included 1-hour oral glucose tolerance results and the presence of gestational diabetes mellitus (GDM). Univariate and multivariate analyses were performed.

Results: A total of 189 women participated; 48% reported an SSD and 18.5% reported FS. SSD and FS were associated with higher oral glucose tolerance values: SSD (116 +/- 31 vs 105 +/- 23; P = .008) and FS (118 +/- 34 vs 108 +/- 25; P = .04). Both SSD (10.2% vs 1.1%; P = .008) and FS (14.3% vs 3.3%; P = .009) were associated with a higher incidence of GDM. Even after controlling for potential confounders, SSD and FS remained associated with GDM.

Conclusion: SSD and FS are associated with glucose intolerance in pregnancy.

Copyright (c) 2010 Mosby, Inc. All rights reserved.

Source: PubMed

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