Prevalence of human KI and WU polyomaviruses in children with acute respiratory tract infection in China

Abstract

The KI and WU polyomaviruses were found in 11 (2.7%) and 17 (4.2%) of 406 nasopharyngeal aspirates, respectively, from children with acute respiratory tract infection (ARTI). The phylogenetic analysis indicates that they are all in the same cluster as the prototype strains. Our findings suggest that they are common in children with ARTI in China.

Figures

FIG. 1.

Seasonal distribution of KIPyV (A) and WUPyV (B) in children with ARTI from December 2006 until approximately November 2007. The percentage of specimens positive for KIPyV (A) and WUPyV (B) by month are shown.

FIG. 2.

Phylogenetic analysis of the deduced amino acid sequences of the WUPyV VP2 gene (250 bp) (A) and KIPyV VP1 gene (204 bp) (B) with reference strains. Phylogenetic trees were constructed by the neighbor-joining method by using MEGA 3.1, and bootstrap values were determined by 1,000 replicates. Viral sequences in marks were generated from the present study; representative WUPyV and KIPyV sequences and other polyomaviruses from GenBank are indicated by isolate name. The GenBank accession numbers of each strain are given in parentheses.