Slow cortical potential neurofeedback and self-management training in outpatient care for children with ADHD: study protocol and first preliminary results of a randomized controlled trial

Hanna Christiansen, Verena Reh, Martin H Schmidt, Winfried Rief, Hanna Christiansen, Verena Reh, Martin H Schmidt, Winfried Rief

Abstract

Background: Treatment for children with attention deficit/hyperactivity disorder (ADHD) today is predominantly pharmacological. While it is the most common treatment, it might not always be the most appropriate one. Moreover, long term effects remain unclear. Behavior therapy (BT) and non-pharmacological treatments such as neurofeedback (NF) are promising alternatives, though there are no routine outpatient care/effectiveness studies yet that have included children with medication or changes in medication.

Methods/design: This paper presents the protocol of a randomized controlled trial to compare the effectiveness of a Slow Cortical Potential (SCP) NF protocol with self-management (SM) in a high frequent outpatient care setting. Both groups (NF/SM) receive a total of 30 high frequent therapy sessions. Additionally, 6 sessions are reserved for comorbid problems. The primary outcome measure is the reduction of ADHD core symptoms according to parent and teacher ratings.

Preliminary results: Untill now 58 children were included in the study (48 males), with a mean age of 8.42 (1.34) years, and a mean IQ of 110 (13.37). Conners-3 parent and teacher ratings were used to estimate core symptom change. Since the study is still ongoing, and children are in different study stages, pre-post and follow-up results are not yet available for all children included. Preliminary results suggest overall good pre-post effects, though. For parent and teacher ratings an ANOVA with repeated measures yielded overall satisfying pre-post effects (η (2) 0.175-0.513). Differences between groups (NF vs. SM) could not yet be established (p = 0.81).

Discussion: This is the first randomized controlled trial to test the effectiveness of a NF protocol in a high frequent outpatient care setting that does not exclude children on or with changes in medication. First preliminary results show positive effects. The rationale for the trial, the design, and the strengths and limitations of the study are discussed.

Trial registration: This trial is registered in www.clinicaltrials.gov as NCT01879644.

Keywords: ADHD; behavior therapy; effectiveness; neurofeedback; self-management; slow cortical potential training.

Figures

Figure 1
Figure 1
Flow-chart of the study. R = Randomization of parents to either PE or PE+SU.
Figure 2
Figure 2
Neurofeedback Protocol with three therapy blocks and a total of 30 sessions.

References

    1. Abikoff H., Hechtman L., Klein R. G., Gallagher R., Fleiss K., Etcovitch J. O. Y., et al. . (2004a). Social functioning in children with ADHD treated with long-term methylphenidate and multimodal psychosocial treatment. J. Am. Acad. Child Adolesc. Psychiatry 43, 820–829. 10.1097/01.chi.0000128797.91601.1a
    1. Abikoff H., Hechtman L., Klein R. G., Weiss G., Fleiss K., Etcovitch J. O. Y., et al. . (2004b). Symptomatic improvement in children with ADHD treated with long-term methylphenidate and multimodal psychosocial treatment. J. Am. Acad. Child Adolesc. Psychiatry 43, 802–811. 10.1097/
    1. Anney R. J. L., Lasky-Su J., Ó’Dúshláine C., Kenny E., Neale B., Mulligan A., et al. . (2008). Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B, 1369–1378. 10.1002/ajmg.b.30871
    1. Antrop I., Stock P., Verté S., Wiersema J. R., Baeyens D., Roeyers H. (2006). ADHD and delay aversion: the influence of non-temporal stimulation on choice for delayed rewards. J. Child Psychol. Psychiatry 47, 1152–1158. 10.1111/j.1469-7610.2006.01619.x
    1. Arnold L. E., Lofthouse N., Hersch S., Pan X., Hurt E., Bates B., et al. . (2012). EEG neurofeedback for ADHD double-blind sham-controlled randomized pilot feasibility trial. J. Atten. Disord. 17, 410–419. 10.1177/1087054712446173
    1. Arnold D. S., O’Leary S. G., Wolff L. S., Acker M. M. (1993). The parenting scale: a measure of dysfunctional parenting in discipline situations. Psychol. Assess. 5, 137–144 10.1037//1040-3590.5.2.137
    1. Arns M., de Ridder S., Strehl U., Breteler M., Coenen A. (2009). Efficacy of neurofeedback treatment in ADHD: the effects on inattention, impulsivity and hyperactivity: a meta-analysis. Clin. EEG Neurosci. 40, 180–189. 10.1177/155005940904000311
    1. Arns M., Heinrich H., Strehl U. (2014). Evaluation of neurofeedback in ADHD: the long and winding road. Biol. Psychol. 95, 108–115. 10.1016/j.biopsycho.2013.11.013
    1. Bachmann M., Bachmann C., Rief W., Mattejat F. (2008). Efficacy of psychiatric and psychotherapeutic interventions in children and adolescents with psychiatric disorders—a systematic evaluation of meta-analyses and reviews: part II: ADHD and conduct disorders. Z. Kinder Jugendpsychiatr. Psychother. 36, 321–333. 10.1024/1422-4917.36.5.321
    1. Barbaresi W. J., Katusic S. K., Colligan R. C., Pankratz V. S., Weaver A. L., Weber K. J., et al. . (2002). How common is attention-deficit/hyperactivity disorder? Incidence in a population-based birth cohort in Rochester, Minn. Arch. Pediatr. Adolesc. Med. 156, 217–224. 10.1001/archpedi.156.3.217
    1. Berger I., Dor T., Neo Y., Goldzweig G. (2008). Attitudes toward Attention-Deficit Hyperactivity Disorder (ADHD) treatment: parents‘ and children’s perspecitives. J. Child Neurol. 23, 1036–1042. 10.1177/0883073808317726
    1. Bitsakou P., Psychogiou L., Thompson M., Sonuga-Barke E. J. S. (2009). Delay aversion in attention deficit/hyperactivity disorder: an empirical investigation of the broader phenotype. Neuropsychologia 47, 446–456. 10.1016/j.neuropsychologia.2008.09.015
    1. Christiansen H., Oades R. D., Psychogiou L., Hauffa B. P., Sonuga-Barke E. J. S. (2010). Does the cortisol response to stress mediate the link between expressed emotion and oppositonal behavior in Attention-Deficit/Hyperactivity-Disorder (ADHD)? Behav. Brain Funct. 6:45. 10.1186/1744-9081-6-45
    1. Christiansen H., Röhrle B. (2012). “Psychische störungen des kindes- und jugendalters,” in Klinische Psychologie und Psychotherapie für Bachelor Studierende, Bd. I, eds Berking M., Rief W. (Berlin U. A.: Springer; ), 213–234.
    1. Conners C. K. (2008). Conners 3rd Edition. Manual. North Tonawanda, NY: Multi-Health Systems.
    1. Dalen L., Sonuga-Barke E. J. S., Hall M., Remington B. (2004). Inhibitory deficits, delay aversion and preschool AD/HD: implications for the dual pathway model. Neural Plast. 11, 1–11. 10.1155/NP.2004.1
    1. Dalsgaard S., Nielsen H. S., Simonsen M. (2013). Five-fold increase in national prevalence rates of attention-deficit/hyperactivity disorder medications for children and adolescents with autism spectrum disorder, attention-deficit/hyperactivity disorder and other psychiatric disorders: a Danish register-based study. J. Child Adolesc. Psychopharmacol. 23, 432–439. 10.1089/cap.2012.0111
    1. DeBeus R. (2006). “Progress in efficacy studies of EEG biofeedback for ADHD,” in Paper Presented at the Annual Meeting of the American Psychiatric Association (Toronto, Canada).
    1. DeBeus R. J., Kaiser D. A. (2011). Neurofeedback with children with attention deficit hyperactivity disorder: a randomized doubleblind placebo-controlled study. Neurofeedback Neuromodulation Tech. Appl. 16, 127–152 10.1016/B978-0-12-382235-2.00005-6
    1. Delmo C., Weiffenbach O., Gabriel M., Stadler C., Poustka F. (2011). Diagnostisches Interview Kiddie-Sads-Present and Lifetime Version (K-SADS-PL). 5. Auflage der deutschen Forschungsversion, erweitert um ICD-10-Diagnostik. Frankfurt: Klinik für Psychiatrie und Psychotherapie des Kindes-und Jugendalters, 1–241.
    1. Domsch H., Lohaus A. (2010). Elternstressfragebogen (ESF). Göttingen und Bern: Hogrefe.
    1. Drabick D. A. G., Gadow K. D., Sprafkin J. (2006). Co-occurrence of conduct disorder and depression in a clinic-based sample of boys with ADHD. J. Child Psychol. Psychiatry 47, 766–774. 10.1111/j.1469-7610.2006.01625.x
    1. Drechsler R., Rizzo P., Steinhausen H.-C. (2009). Zur klinischen Validität einer computergestützten Aufmerksamkeitsbatterie für Kinder (KITAP) bei 7–10-jährigen Kindern mit ADHS: the clinical validity of a computerized test battery for attentional performance for children. Child. Dev. 18, 153–161 10.1026/0942-5403.18.3.153
    1. Drechsler R., Straub M., Doehnert M., Heinrich H., Steinhausen H.-C., Brandeis D. (2007). Controlled evaluation of a neurofeedback training of slow cortical potentials in children with Attention Deficit/Hyperactivity Disorder (ADHD). Behav. Brain Funct. 3:35. 10.1186/1744-9081-3-35
    1. Dreisörner T., Georgiadis J. (2011). Sensitivität und Spezifität computergestützter Verfahren zur Diagnostik von Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) im Kindes-und Jugendalter-Die Testbatterie zur Aufmerksamkeitsprüfung (TAP). Empir. Spec. Educ. 1, 3–19.
    1. Du Paul G. J., Barkley R. A., Connor D. F. (1998). “Stimulants,” in Attention Deficit Hyperactivity Disorder: A Handbbok for Diagnosis and Treatment, ed Barkely R. A. (New York: Guilford Press; ), 510–551.
    1. Esser G. (2011). Lehrbuch der Klinischen Psychologie u. Psychotherapie bei Kindern + Jugendlichen. Stuttgart and New York: Thieme.
    1. Esser G., Blank S. (2011). Efficacy of psychotherapy with children and adolescents. Prax. Kinderpsychol. Kinderpsychiatr. 60, 626–638.
    1. Fabiano G. A., Pelham W. E., Jr., Coles E. K., Gnagy E. M., Chronis-Tuscano A., O’Connor B. C. (2009). A meta-analysis of behavioral treatments for attentiondeficit/hyperactivity disorder. Clin. Psychol. Rev. 29, 129–140. 10.1016/j.cpr.2008.11.001
    1. Gadow K. D., DeVincent C. J., Pomeroy J. (2006). ADHD symptom subtypes in children with pervaisive developmental disorder. J. Autism Dev. Disord. 36, 271–283. 10.1007/s10803-005-0060-3
    1. Gevensleben H., Holl B., Albrecht B., Schlamp D., Kratz O., Studer P., et al. . (2009a). Distinct EEG effects related to neurofeedback training in children with ADHD: a randomized controlled trial. Int. J. Psychophysiol. 74, 149–157. 10.1016/j.ijpsycho.2009.08.005
    1. Gevensleben H., Holl B., Albrecht B., Schlamp D., Kratz O., Studer P., et al. . (2010). Neurofeedback training in children with ADHD: 6-month follow-up of a randomized controlled trial. Eur. Child Adolesc. Psychiatry 19, 715–724. 10.1007/s00787-010-0109-5
    1. Gevensleben H., Holl B., Albrecht B., Vogel C., Schlamp D., Kratz O., et al. . (2009b). Is neurofeedback an efficacious treatment for ADHD? A randomised controlled clinical trial. J. Child Psychol. Psychiatry 50, 780–789. 10.1111/j.1469-7610.2008.02033.x
    1. Graham J., Banaschewski T., Buitelaar J., Coghill D., Danckaerts M., Dittmann R. W., et al. . (2011). European guidelines on managing adverse effects of medication for ADHD. Eur. Child Adolesc. Psychiatry 20, 17–37. 10.1007/s00787-010-0140-6
    1. Greenhill L. L., Halperin J. M., Abikoff H. (1999). Stimulant medications. J. Am. Acad. Child Adolesc. Psychiatry 38, 503–512. 10.1097/00004583-199905000-00011
    1. Heinrich H., Gevensleben H., Strehl U. (2007). Annotation: neurofeedback—train your brain to train behavior. J. Child Psychol. Psychiatry 48, 3–16. 10.1111/j.1469-7610.2006.01665.x
    1. Hodgson K., Hutchinson A. D., Denson L. (2014). Nonpharmacological treatments for ADHD: a meta-analytic review. J. Atten. Disord. 18, 275–282. 10.1177/1087054712444732
    1. Hoerger M. L., Mace F. C. (2006). A computerized test of self-control predicts classroom behavior. J. Appl. Behav. Anal. 39, 147–159. 10.1901/jaba.2006.171-04
    1. Hooley J. M. (1990). “Expressed emotion and depression,” in Depression and Families: Impact and Treatment, ed Keitner G. I. (Washington, DC: American Psychiatry Press; ), 57–83.
    1. Jakobson A., Kikas E. (2007). Cognitive functioning in children with and without attention-deficit/hyperactivity disorder with and without comorbid learning disabilities. J. Learn. Disabil. 40, 194–202. 10.1177/00222194070400030101
    1. Jensen P. S., Arnold L. E., Swanson J. M., Vitiello B., Abikoff H. B., Greenhill L. L., et al. . (2007). 3-year follow-up of the NIMH MTA study. J. Am. Acad. Child Adolesc. Psychiatry 46, 989–1002. 10.1097/CHI.0b013e3180686d48
    1. Kadesjö C., Hagglof B., Kadesjö B., Gillberg C. (2003). Attention-Deficit/Hyperactivity Disorder: review and recommendations for future research. Clin. Child Fam. Psychol. Rev. 4, 183–207.
    1. Kaufman J., Birmaher B., Brent D., Rao U., Ryan N. (1996). Kiddie-Sads-Present and Lifetime Version (K-SADS-PL). Pittsburgh, University of Pittsburgh, School of Medicine; Available online at: .
    1. Kaufmann L., Zieren N., Zotter S., Karall D., Scholl-Bürgi S., Haberlandt E., et al. . (2010). Predictive validity of attentional functions in differentiating children with and without ADHD: a componential analysis. Dev. Med. Child Neurol. 52, 371–378. 10.1111/j.1469-8749.2009.03560.x
    1. Kazdin A. E. (2003). Psychotherapy for children and adolescents. Annu. Rev. Psychol. 54, 253–276. 10.1146/annurev.psych.54.101601.145105
    1. Kuntsi J., Oosterlaan J., Stevenson J. (2001). Psychological mechanisms in hyperactivity: I response inhibition deficit, working memory impairment, delay aversion, or something else?. J. Child Psychol. Psychiatry 42, 199–210. 10.1111/1469-7610.00711
    1. Lansbergen M. M., van Dongen-Boomsma M., Buitelaar J. K., Slaats-Willemse D. (2011). ADHD and EEG-neurofeedback: a double-blind randomized placebo-controlled feasibility study. J. Neural Transm. 118, 275–284. 10.1007/s00702-010-0524-2
    1. Lauth G. W., Schlottke P. F. (2009). Training Mit Aufmerksamkeitsgestörten Kindern. 6th Edn. Weinheim, Basel: Beltz PVU.
    1. Leins U. H. T., Kaller S., Schober F., Weber C., Strehl U. (2006). Neurofeedback for children with ADHD: a comparison of SCP- and theta/beta-protocols. Prax. Kinderpsychol. Kinderpsychiatr. 55, 384–407.
    1. Lidzba K., Christiansen H., Drechsler R. (2013). Conners-3D: Deutsche Adaptation der Conners 3rd EditionTM (Conners 3)TM. Göttingen und Bern: Hogrefe.
    1. Liew A. (2014). EEG biofeedback therapy for ADHD: a systematic review. J. Neurol. Neurosurg. Psychiatry 85:e3 10.1136/jnnp-2014-308883.34
    1. Lofthouse N., Arnold L. E., Hurt E. (2012). Current status of neurofeedback for Attention-Deficit/Hyperactivity Disorder. Curr. Psychiatry Rep. 14, 536–542. 10.1007/s11920-012-0301-z
    1. Logemann H. N., Lansbergen M. M., Van Os T. W., Böcker K. B., Kenemans J. L. (2010). The effectiveness of EEG-feedback on attention, impulsivity and EEG: a sham feedback controlled study. Neurosci. Lett. 479, 49–53. 10.1016/j.neulet.2010.05.026
    1. Malecki K. C., Demaray M. (2002). Measuring perceived social support: development of the child and adolescent social support scale (CASSS). Psychol. Sch. 39, 1–18 10.1002/pits.10004
    1. Malecki C. K., Demaray M. K., Elliott S. N., Nolten P. W. (1999). The Child and Adolescent Social Support Scale. DeKalb, IL: Northern Illinois University.
    1. Meichenbaum D. H., Goodman J. (1971). Training impulsive children to talk to themselves: a means of developing self-control. J. Abnorm. Psychol. 77, 115–126. 10.1037/h0030773
    1. Miller Y. (2001). Erziehung von Kindern im Kindergartenalter: Erziehungsverhalten und Kompetenzüberzeugungen von Eltern und der Zusammenhang zu kindlichen Verhaltensstörungen. University of Braunschweig: Inaugural Dissertation.
    1. Molina B. S., Hinshaw S. P., Eugene Arnold L., Swanson J. M., Pelham W. E., Hechtman L., et al. . (2013). Adolescent substance use in the multimodal treatment study of Attention-Deficit/Hyperactivity Disorder (ADHD)(MTA) as a function of childhood ADHD, random assignment to childhood treatments and subsequent medication. J. Am. Acad. Child Adolesc. Psychiatry 52, 250–263. 10.1016/j.jaac.2012.12.014
    1. Molina B. S. G., Hinshaw S. P., Swanson J. M., Arnold L. E., Vitiello B., Jensen P. S., et al. . (2009). The MTA at 8 Years: prospective follow-up of children treated for combined-type ADHD in a Multisite study. J. Am. Acad. Child Adolesc. Psychiatry 48, 484–500. 10.1097/CHI.0b013e31819c23d0
    1. Monastra V. J., Lynn S., Linden M., Lubar J. F., Gruzelier J., LaVaque T. J. (2005). Electroencephalographic biofeedback in the treatment of Attention-Deficit/Hyperactivity Disorder. Appl. Psychophysiol. Biofeedback 30, 95–114. 10.1007/s10484-005-4305-x
    1. Moriyama T. S., Polanczyk G., Caye A., Banaschweski T., Brandeis D., Rohde L. A. (2012). Evidence-based information on the clinical use of neurofeedback for ADHD. Neurotherapeutics 9, 588–598. 10.1007/s13311-012-0136-7
    1. Mrug S., Molina B. S., Hoza B., Gerdes A. C., Hinshaw S. P., Hechtman L., et al. . (2012). Peer rejection and friendships in children with Attention-Deficit/Hyperactivity Disorder: contributions to long-term outcomes. J. Abnorm. Child Psychol. 40, 1013–1026. 10.1007/s10802-012-9610-2
    1. MTA Cooperative Group (1999). A 14-month randomized clinical trial of treatment strategies for Attention-Deficit/Hyperactivity Disorder. The MTA Cooperative Group. Multimodal treatment study of children with ADHD. Arch. Gen. Psychiatry 12, 1073–1086. 10.1001/archpsyc.56.12.1073
    1. Nestoriuc Y., Christiansen H., Martin A., Rief W. (2011). Efficacy of neurofeedback treatment studies in ADHD: a meta-analysis. Poster Presentation at the 2011 Budapest Meeting of the European Network on Hyperkinetic Disorders(Eunethydis) (Budapest, Hungary: ).
    1. Nieweg E. H. (2010). Does ADHD medication stop working after 2-3 years? On the surprising but little-known follow-up of the MTA study. Tijdschr. Psychiatr. 52, 245–254.
    1. Perreau-Linck E., Lessard N., Lévesque J., Beauregard M. (2010). Effects of neurofeedback training on inhibitory capacities in ADHD children: a single-blind, randomized, placebo-controlled study. J. Neurother. 14, 229–242 10.1080/10874208.2010.501514
    1. Phelan T. W. (2003). 1–2-3 Magic Effective Discipline for Children 2–12. Glen Ellyn, Illinois: ParentMagic, Inc.
    1. Picard C., Moreau G., Guay M. C., Achim A. (2006). “Double double-blind sham study of neurofeedback treatment in children with ADHD,” in Proceedings of the Meeting of the International Society for Neurofeedback and Research: 2006 (Atlanta, GA).
    1. Ravens-Sieberer U., Bettge S., Erhart M. (2003). Lebensqualität von kindern und jugendlichen. Ergebnisse aus der pilotphase des kinder- und jugendgesundheitssuveys. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz [Epub ahead of print]. 46, 340–345 10.1007/s00103-002-0562-5
    1. Ravens-Sieberer U., Bullinger M. (1998a). Assessing health-related quality of life in chronically ill children with the German KINDL: first psychometric and content analytical results. Qual. Life Res. 7, 399–407. 10.1023/a:1008853819715
    1. Ravens-Sieberer U., Bullinger M. (1998b). News from the KINDL-Questionnaire—A new version for adolescents. Qual. Life Res. 7, 653.
    1. Reh V., Schmidt M. H., Lam L., Schimmelmann B. B., Hebebrand J., Rief W., et al. . (2013). Behavioral assessment of core ADHD symptoms using the QbTest. J. Atten. Disord. [Epub ahead of print]. 10.1177/1087054712472981
    1. Reh V., Schmidt M., Rief W., Christiansen H. (2014). Preliminary evidence for altered motion tracking-based hyperactivity in ADHD siblings. Behav. Brain Funct. 10:7. 10.1186/1744-9081-10-7
    1. Renner G., Irblich D. (2007). Testbatterie zur Aufmerksamkeitsprüfung für Kinder (KITAP). Z. Entwicklungspsychol. Padagog. Psychol. 39, 206–214 10.1026/0049-8637.39.4.206
    1. Renner G., Lessing T., Krampen G., Irblich D. (2012). Reliabilität und Retest-Stabilität der “Testbatterie zur Aufmerksamkeitsprüfung für Kinder” (KITAP) bei 6-bis 7-jährigen Kindern. Z. Neuropsychol. 23, 27–36 10.1024/1016-264x/a000059
    1. Röhrle B., Sommer G., Nestmann F. (1998). Netzwerkintervention. Fortschritte der Gemeindepsychologie und Gesundheitsförderung. (Vol. 2), Tübingen: dgvt Verlag.
    1. Röthlisberger M., Neuenschwander R., Michel E., Roebers C. M. (2010). Exekutive Funktionen: Zugrundeliegende kognitive Prozesse und deren Korrelate bei Kindern im späten Vorschulalter. Z. Entwicklungspsychol. Padagog. Psychol. 42, 99–110 10.1026/0049-8637/a000010
    1. Sagvolden T. (2000). Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of Attention-Deficit/Hyperactivity Disorder (AD/HD). Neurosci. Biobehav. Rev. 24, 31–39. 10.1016/s0149-7634(99)00058-5
    1. Saile H. (1996). Metaanalyse zur effektivität psychologischer behandlung hyperaktiver kinder. Z. Klin. Psychol. 25, 190–207.
    1. Sattler J. M. (2008). Assessment of Children. San Diego: Jerome M. Sattler, Publishing, Inc.
    1. Schachar R., Taylor E., Wieselberg M., Thorley G., Rutter M. (1987). Changes in family function and relationships in children who respond to Methylphenidate. J. Am. Acad. Child Adolesc. Psychiatry 26, 728–732. 10.1097/00004583-198709000-00019
    1. Schachter H. M., Pham B., King J., Langford S., Moher D. (2001). How efficacious and safe is short-acting methylphenidate for the treatment of Attention-Deficit Disorder in children and adolescents? A meta-analysis. CMAJ 165, 1475–1488.
    1. Schlegelmilch F., Markert S., Berkes S., Schellhorn K. (2004). Online ocular artifact removal for dc-EEG-signals: estimation of dc-level. Biomed. Tech. 49, 340–341.
    1. Schmidt M., Reh V., Hirsch O., Rief W., Christiansen H. (2013). Assessment of ADHD symptoms and the issue of cultural variation. Are conners 3rd rating scales applicable to children and parents with migration background?. J. Atten. Disord. [Epub ahead of print]. 10.1177/1087054713493319
    1. Schöning S., Steins G., Berek M. (2002). Das Selbstkonzept von Kindern mit Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHD) und dessen Veränderung mit Methylphenidat. Kindheit Entwicklung 11, 38–47 10.1026//0942-5403.11.1.38
    1. Semrud-Clikeman M., Bledsoe J. (2011). Updates on Attention-Deficit/Hyperactivity Disorder and learning disorders. Curr. Psychiatry Rep. 13, 364–373. 10.1007/s11920-011-0211-5
    1. Sobeh J. (2010). Aufmerksamkeitsfunktionen und Ihre Entwicklung bei Vor- und Grundschulkindern. Göttingen: Cuvillier-Verlag.
    1. Solanto M. V., Abikoff H., Sonuga-Barke E., Schachar R., Logan G. D., Wigal T., et al. . (2001). The ecological validity of delay aversion and response inhibition as measures of impulsivity in AD/HD: a supplement to the NIMH multimodal treatment study of AD/HD. J. Abnorm. Child Psychol. 29, 215–228. 10.1023/A:1010329714819
    1. Sonuga-Barke E. J. S. (2002). Psychological heterogeneity in AD/HD—a dual pathway model of behaviour and cognition. Behav. Brain Res. 130, 29–36. 10.1016/S0166-4328(01)00432-6
    1. Sonuga-Barke E. J. S. (2011). Editorial: ADHD as a reinforcement disorder- moving from general effects to identifying (six) specific models to test. J. Child Psychol. Psychiatry 52, 917–918. 10.1111/j.1469-7610.2011.02444.x
    1. Sonuga-Barke E. J. S., Brandeis D., Cortese S., Daley D., Ferrin M., Holtmann M., et al. . (2013). Nonpharmacological interventions for adhd: systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments. Am. J. Psychiatry 170, 275–289. 10.1176/appi.ajp.2012.12070991
    1. Stein D. S., Blum N. J., Barbaresi W. J. (2011). Developmental and behavioral disorders through the life-span. Pediatrics 128, 364–373. 10.1542/peds.2011-0266
    1. Steinhausen H. C., Bisgaard C. (2014). Nationwide time trends in dispensed prescriptions of psychotropic medication for children and adolescents in Denmark. Acta Psychiatr. Scand. 129, 221–231. 10.1111/acps.12155
    1. Strehl U. (2009). Slow cortical potentials neurofeedback. J. Neurother. 13, 117–126 10.1080/10874200902885936
    1. Strehl U., Goth G., Klinger C., Hinterberger T., Birbaumer N. (2006). Self-regulation of slow cortical potentials: a new treatment for children with Attention-Deficit/Hyperactivity Disorder. Pediatrics 118, e1530–e1540. 10.1542/peds.2005-2478
    1. Strehl U., Leins U., Heinrich H. (2011). “Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS),” in BiofeedbacK Grundlagen, Indikationen, Kommunikation, Vorgehen, eds Rief W., Birbaumer N. (Stuttgart: Schattauer; ), 238–426.
    1. Swanson J., Arnold L. E., Kraemer H., Hechtman L., Molina B., Hinshaw S., et al. . (2008). Evidence, interpretation and qualification from multiple reports of long-term outcomes in the Multimodal Treatment Study of children with ADHD (MTA). J. Atten. Disord. 12, 15–43. 10.1177/1087054708319525
    1. Swanson J. M., Kraemer H. C., Hinshaw S. P., Arnold L. E., Conners C. K., Abikoff H. B., et al. . (2001). Clinical relevance of the primary findings of the MTA: success rates based on severity of ADHD and ODD symptoms at the end of treatment. J. Am. Acad. Child Adolesc. Psychiatry 40, 168–179. 10.1097/00004583-200102000-00011
    1. Taylor E., Chadwick O., Heptinstall E., Danckaerts M. (1996). Hyperactivity and conduct problems as risk factors for adolescence development. J. Am. Acad. Child Adolesc. Psychiatry 35, 1213–1226. 10.1097/00004583-199609000-00019
    1. Taylor E. A., Sandberg S., Thorley G., Giles S. (1991). The Epidemiology of Childhood Hyperactivity. Oxford: Oxford University Press.
    1. Tripp G., Wickens J. R. (2009). Neurobiology of ADHD. Neuropharmacology 57, 579–589. 10.1016/j.neuropharm.2009.07.026
    1. Tully L. A., Arseneault L., Caspi A., Moffitt T. E., Morgan J. (2004). Does maternal warmth moderate the effects of birth weight on twins’ Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms and low IQ?. J. Consult. Clin. Psychol. 72, 218–226. 10.1037/0022-006X.72.2.218
    1. Ulberstad F. (2012). QbTest Technical Manual (rev. eD). Stockholm, Sweden: Qbtech AB.
    1. U.S. Department of Health and Human Services. Mental Health (1999). A Report of the Surgeon General. Rockville, MD: U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Adminstration, Center for Mental Health Services, Nation Institutes of Health, National Institute of Mental Health.
    1. Vakil E., Blachstein H., Wertman-Elad R., Greenstein Y. (2012). Verbal learning and memory as measured by the rey-auditory verbal learning test: ADHD with and without learning disabilities. Child Neuropsychol. 18, 449–466. 10.1080/09297049.2011.613816
    1. van de Loo-Neus G. H. H., Rommelse N., Buitelaar J. K. (2011). To stop or not to stop? How long should medication treatment of Attention-Deficit Hyperactivity Disorder be extended?. Eur. Neuropsychopharmacol. 21, 584–599. 10.1016/j.euroneuro.2011.03.008
    1. Van der Oord S., Prins P. J., Oosterlaan J., Emmelkamp P. M. (2008). Efficacy of methylphenidate, psychosocial treatments and their combination in school-aged children with ADHD: a metaanalysis. Clin. Psychol. Rev. 28, 783–800. 10.1016/j.cpr.2007.10.007
    1. Visser S. N., Lesesne C. A. (2003). Mental health in the United States: prevalence of diagnosis and medication treatment for Attention-Deficit Hyperactivity Disorder: United States. MMWR Morb. Mortal. Wkly. Rep. 54, 842–847.
    1. Whalen C. K., Henker B. (1991). Therapies for hyperactive children: comparisons, combinations and compromises. J. Consult. Clin. Psychol. 59, 126–137. 10.1037/0022-006X.59.1.126
    1. Willcutt E. G., Pennington B. F., Oson R. K., Chhabildas N., Huslander J. (2005). Neuropsychological analyses of comorbidity between reading disability and attention deficit hyperactivity disorder: in search of the common deficit. Dev. Neuropsychol. 27, 35–78. 10.1207/s15326942dn2701_3
    1. Zimmermann P., Gondan M., Fimm B. (2002). KITAP Testbatterie zur Aufmerksamkeitsprüfung Für Kinder. Herzogenrath: Psychologische Testsysteme.
    1. Zwi M., Jones H., Thorgaard C., York A., Dennis J. A. (2011). Parent training interventions for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 5 to 18 years. Cochrane Database Syst. Rev. 2011:CD003018. 10.1002/14651858.CD003018.pub3

Source: PubMed

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