Can meditation improve attention in older adults? Study protocol for a 4-week proof-of-concept intervention

Lindsay S Nagamatsu, Sabrina D Ford, Lindsay S Nagamatsu, Sabrina D Ford

Abstract

Background: Falls are a major health care concern for our aging population. Previous research has identified impaired sustained attention as a risk factor for falls. Recently, meditation has been shown to improve different types of attention in various populations. However, there are no studies to date examining whether meditation training can improve sustained attention and mobility in older adults.

Methods: We are conducting a 4-week proof-of-concept meditation intervention. We will recruit community-dwelling older adults. Participants will be randomized into one of two groups: (1) meditation training or (2) music listening (control). All participants will complete three 20-min group sessions per week and will be encouraged to continue their practice independently on the remaining days each week. Our primary outcome measure is behavioral performance on the Sustained Attention to Response Task (SART). Our secondary and tertiary outcomes include electroencephalograms (EEG) to assess attention and cognitive processing, mobility, and executive function.

Discussion: Our proof-of-concept intervention aims to examine whether meditation training can improve sustained attention in older adults, who are known to be susceptible to falls. Importantly, our research has the potential to inform future clinical trials aimed at improving mobility and reducing falls risk in our aging population.

Trial registration: Clinicaltrials.gov ID NCT03417635.

Keywords: Attention; EEG; Falls risk; Intervention; Meditation; Mobility.

Conflict of interest statement

Ethics approval for this study was obtained from the Health Sciences Research Ethics Board at Western University, Project ID 110598 (approval attached).Not applicable.The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

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Fig. 1
Schedule of enrolment, interventions, and assessments

References

    1. Anstey KJ, von Sanden C, Luszcz MA. An 8-year prospective study of the relationship between cognitive performance and falling in very old adults. J Am Geriatr Soc. 2006;54:1169–1176. doi: 10.1111/j.1532-5415.2006.00813.x.
    1. Tinetti ME, Speechley M, Ginter SF. Risk factors for falls among elderly persons living in the community. N Engl J Med. 1988;319:1701–1707. doi: 10.1056/NEJM198812293192604.
    1. Montero-Odasso M, Speechley M. Falls in cognitively impaired older adults: implications for risk assessment and prevention. J Am Geriatr Soc. 2018;66:367–375. doi: 10.1111/jgs.15219.
    1. Holtzer R, Friedman R, Lipton RB, Katz M, Xue X, Verghese J. The relationship between specific cognitive functions and falls in aging. Neuropsychol. 2007;21:540–548. doi: 10.1037/0894-4105.21.5.540.
    1. Nagamatsu LS, Voss M, Neider MB, Gaspar JG, Handy TC, Kramer AF, Liu-Ambrose T. Increased cognitive load leads to impaired mobility decisions in seniors at risk for falls. Psychol Aging. 2011;26:253–259. doi: 10.1037/a0022929.
    1. Springer S, Giladi N, Peretz C, Yogev G, Simon ES, Hausdorff JM. Dual-tasking effects on gait variability: the role of aging, falls, and executive function. Mov Disord. 2006;21:950–957. doi: 10.1002/mds.20848.
    1. Nagamatsu LS, Munkacsy M, Liu-Ambrose T, Handy TC. Altered visual-spatial attention to task-irrelevant information is associated with falls risk in older adults. Neuropsychologia. 2013;51:3025–3032. doi: 10.1016/j.neuropsychologia.2013.10.002.
    1. Nagamatsu LS, Carolan P, Liu-Ambrose T, Handy TC. Are impairments in visual-spatial attention a critical factor for increased falls risk in seniors? An event-related potential study. Neuropsychologia. 2009;47:2749–2755. doi: 10.1016/j.neuropsychologia.2009.05.022.
    1. Nagamatsu LS, Kam JWY, Liu-Ambrose T, Chan A, Handy TC. Mind-wandering and falls risk in older adults. Psychol Aging. 2013;28:685–691. doi: 10.1037/a0034197.
    1. Deschamps T, Magnard J, Cornu C. Postural control as a function of time-of-day: influence of a prior strenuous running exercise or demanding sustained-attention task. J Neuroeng Rehabil. 2013;10:26. doi: 10.1186/1743-0003-10-26.
    1. Tang YY, Holzel BK, Posner MI. The neuroscience of mindfulness meditation. Nat Rev Neurosci. 2015;16:213–225. doi: 10.1038/nrn3916.
    1. Househam AM, Peterson CT, Mills PJ, Chopra D. The effects of stress and meditation on the immune system, human microbiota, and epigenetics. Adv Mind Body Med. 2017;31:10–25.
    1. Lehmann D, Faber PL, Tei S, Pascual-Marqui RD, Milz P, Kochi K. Reduced functional connectivity between cortical sources in five meditation traditions detected with lagged coherence using EEG tomography. NeuroImage. 2012;60:1574–1586. doi: 10.1016/j.neuroimage.2012.01.042.
    1. Manna A, Raffone A, Perrucci MG, Nardo D, Ferretti A, Tartaro A, Londei A, Del Gratta C, Belardinelli MO, Romani GL. Neural correlates of focused attention and cognitive monitoring in meditation. Brain Res Bull. 2010;82:46–56. doi: 10.1016/j.brainresbull.2010.03.001.
    1. Grecucci A, Pappaianni E, Siugzdaite R, Theuninck A, Job R. Mindful emotion regulation: exploring the neurocognitive mechanisms behind mindfulness. Biomed Res Int. 2015;2015:1–9. doi: 10.1155/2015/670724.
    1. Colzato LS, Sellaro R, Samara I, Baas M, Hommel B. Meditation-induced states predict attentional control over time. Conscious Cogn. 2015;37:57–62. doi: 10.1016/j.concog.2015.08.006.
    1. Hodgins HS, Adair KC. Attentional processes and meditation. Conscious Cogn. 2010;19:872–878. doi: 10.1016/j.concog.2010.04.002.
    1. Zeidan F, Johnson SK, Diamond BJ, David Z, Goolkasian P. Mindfulness meditation improves cognition: evidence of brief mental training. Conscious Cogn. 2010;19:597–605. doi: 10.1016/j.concog.2010.03.014.
    1. Malinowski P, Moore AW, Mead BR, Gruber T. Mindful aging: the effects of regular brief mindfulness practice on electrophysiological markers of cognitive and affective processing in older adults. Mindfulness (N Y) 2017;8:78–94. doi: 10.1007/s12671-015-0482-8.
    1. Pagnoni G, Cekic M. Age effects on gray matter volume and attentional performance in Zen meditation. Neurobiol Aging. 2007;28:1623–1627. doi: 10.1016/j.neurobiolaging.2007.06.008.
    1. Lomas T, Ivtzan I, Fu C. A systemativ review of the neurophysiology of mindfulness on EEG oscillations. Neurosci Biobehav Rev. 2015;57:401–410. doi: 10.1016/j.neubiorev.2015.09.018.
    1. Ainsworth B, Eddershaw R, Meron D, Baldwin DS, Garner M. The effect of focused attention and open monitoring meditation on attention network function in healthy volunteers. Psychiatry Res. 2013;210:1226–1231. doi: 10.1016/j.psychres.2013.09.002.
    1. Wallace BA. Unlocking the power of the focused mind. Sommerville: Wisdom Publications Inc; 2006.
    1. Tsai MH, Chou WL. Attentional orienting and executive control are affected by different types of meditation practice. Conscious Cogn. 2016;46:110–126. doi: 10.1016/j.concog.2016.09.020.
    1. Cahn B, Polich J. Meditation states and traits: EEG, ERP and neuroimaging studies. Psychol Bull. 2006;132:180–211. doi: 10.1037/0033-2909.132.2.180.
    1. Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189–198. doi: 10.1016/0022-3956(75)90026-6.
    1. Yesavage JA. Geriatric depression scale. Psychopharmacol Bull. 1988;24:709–711.
    1. Groll DL, To T, Bombardier C, Wright JG. The development of a comorbidity index with physical function as the outcome. J Clin Epidemiol. 2005;58:595–602. doi: 10.1016/j.jclinepi.2004.10.018.
    1. Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist. 1969;9:179–186. doi: 10.1093/geront/9.3_Part_1.179.
    1. Podsiadlo D, Richardson S. The timed “up and go”: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991;39:142–148. doi: 10.1111/j.1532-5415.1991.tb01616.x.
    1. Guralnik JM, Ferrucci L, Simonsick EM, Salive ME, Wallace RB. Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med. 1995;332:556–562. doi: 10.1056/NEJM199503023320902.
    1. Gloster AT, Rhoades HM, Novy D, Klotsche J, Senior A, Kunik M, Wilson N, Stanley MA. Psychometric properties of the Depression Anxiety and Stress Scale-21 in older primary care patients. J Affect Disord. 2008;110:248–259. doi: 10.1016/j.jad.2008.01.023.
    1. Eberth J, Sedlmeier P. The effects of mindfulness meditation: a meta-analysis. Mindfulness. 2012;3:174–189. doi: 10.1007/s12671-012-0101-x.

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