Lower urinary tract symptoms and erectile dysfunction in men from the Republic of Moldova

I Dumbraveanu, E Ceban, P Banov, I Dumbraveanu, E Ceban, P Banov

Abstract

A transversal study based on 1,186 respondents' group questioning was realized in order to study lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) prevalence in men from the Republic of Moldova. The basic tools used included IPSS (International Prostate Symptom Score) and IIEF-5 (International Index of Erectile Function) questionnaires as well as general questions to assess the presence of risk factors. ED total prevalence in the studied population was 47.1%, inclusively mild form - 22%, slightly moderate - 12.4%, moderate - 7.6% and severe - 51%. The overall prevalence of LUTS symptoms, according to the IPSS score, was 42.9% with significant variations in males up to 40 years - 15.7% and over this age - 62.6% (p <0.05). LUTS presence correlates directly with erectile dysfunction prevalence, especially in men over the age of 40, where 82% of those with LUTS will also have ED. LUTS and ED symptomatologies have an increased prevalence among men from the Republic of Moldova, especially over the age of 40. Statistically significant correlations between these two pathologies were demonstrated. These correlations need to be taken into account both in diagnosis establishment and in concomitant treatment.

Keywords: correlation; erectile dysfunction; lower urinary tract symptoms; men’s health.

References

    1. Rosen R, Altwein J, Boyle P, Kirby R. Lower Urinary Tract Symptoms and Male Sexual Dysfunction: The Multinational Survey of the Aging Male (MSAM-7) European Urology. 2003;44(6):637–649.
    1. Rosen RC. Update on the relationship between sexual dysfunction and lower urinary tract symptoms/benign prostatic hyperplasia. Curr Opin Urol. 2006 Jan;16(1):11–9.
    1. Wein AJ, Coyne KS, Tubaro A, et al. The impact of lower urinary tract symptoms on male sexual health: EpiLUTS. BJU Int 2009. 103(Suppl 3):33–41.
    1. Seftel AD, De la Rosette J, Birt J, Porter V, Zartotsky V, Viktrup V. Coexisting lower urinary tract symptoms and erectile dysfunction: a systematic review of epidemiological data. IJCP. 2013;67(1):32–45. DOI: 10.1111/ijcp.12044.
    1. McVary K. Lower urinary tract symptoms and sexual dysfunction: epidemiology and pathophysiology. BJU Int. 2006;(Suppl 2):23–8. Apr;97 discussion 44-5.
    1. Orabi H, Albersen M., Lue TF. Association of lower urinary tract symtoms and erectile dysfunction: pathophysiological aspects and implications for clinical management. Int J of Impot. 2011;23(3):99–108.
    1. Stief CG, Porst H, Neuser D. A randomised, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia. Eur Urol. 2008 Jun;53(6):1236–1244. Epub 2008 Feb. 4.
    1. Apostolidis A, Rantell A, Anding R, Kirschner-Hermanns R, Cardozo L. How does lower urinary tract dysfunction (LUTD) affect sexual function in men and women? ICI-RS 2015-Part 2. Neurourol Urodyn. 2017;36(4):869–875. doi: 10.1002/nau.23088.
    1. Ojewola RW, Oridota ES, Balogun OS, Ogundare EO, Alabi TO. Lower Urinary Tract Symptoms: Prevalence, Perceptions, and Healthcare-Seeking Behavior amongst Nigerian Men. World J Mens Health. 2016;34(3):200–208. doi: 10.5534/wjmh.2016.34.3.200.
    1. Gonsalez-Sanchez B, Cendejas-Gomez J, Alejandro Rivera-Ramirez J., et al. The correlation between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED): results from a survey in males from Mexico City (MexiLUTS) World J Urol (2016) 34: 979. doi:10.1007/s00345-015-1703-4.
    1. Ngai KH, Kwong AS, Wong AS, Tsui WW. Erectile dysfunction and lower urinary tract symptoms: prevalence and risk factors in a Hong Kong primary care setting. Hong Kong Med J. 2013;19(4):311–6. doi: 10.12809/hkmj133770.
    1. Korneyevl A, Alexeeva TA, Al-Shukri SH, et al. Prevalence and risc factors for erectile dysfunction and lower urinary tract symptoms in Russian Federation men:analysis from a national population based multicenter study. Int I Impot Res. 2016;28(2):74–79. doi:10.1038/ijir.2016.8.Epub2016Feb11.
    1. Song Jian, Shao Qiang, Tian Ye, Chen Shan. Lower Urinary Tract Symptoms, Erectile Dysfunction, and Their Correlation in Men Aged 50 Years and Above: A Cross-Sectional Survey in Beijing, China. Med Sci Monit. 2014;20:2806–2810. doi:10.12659/MSM.891180.
    1. Demir O, Akgul K, Akar Z, et al. Association between severity of lower urinary tract symptoms, erectile dysfunction and metabolic syndrome. Aging Male. 2009;12(1):29–34.
    1. Gacci M, Eardley I, Giuliano F, et al. Criticla analysis of the relationship between sexual dysfunction and lower urinary tract symptoms due to benign prostatic hyperplasia. Eur Urol 2011. Nr.60 (4);809-25. doi:10.1016/j.eururo.2011.06.037.
    1. Jung J, Jae S, Kam S, Hyun J. Corelation between lower urinary tract symtoms(LUTS) and sexual Function in benign prostatic hyperplasia:Impact of tteatment of LUTS on sexual function. J Sex Med. 2009;6:2299–2304.
    1. Mirone V, Sessa A, Giuliano F, Berges R, Kirby M, Moncada I. Current benign prostatic hyperplasia treatment: impact on sexual function and management of related sexual adverse events. Int J Clin Pract. 2011;65(9):1005–13. doi: 10.1111/j.1742-1241.2011.02731.x.

Source: PubMed

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