Effectiveness of physical activity on patients with depression and Parkinson's disease: A systematic review

Pei-Ling Wu, Megan Lee, Tzu-Ting Huang, Pei-Ling Wu, Megan Lee, Tzu-Ting Huang

Abstract

Aim: In this paper we aimed to systematically review the literature on physical activity's effect on depressive symptoms in Parkinson disease.

Background: Depression is a common symptom of Parkinson's disease and is associated with increased disability, rapid progression of motor symptoms, mortality, and adverse effects on Quality of Life.

Design: A systematic review of primary research was undertaken and conducted according to the Preferred Reporting Items for Systematic Reviews.

Data sources: Databases Scopus, Psycho-info, CINAHL, PubMed, and ProQuest Cochrance were searched from January 2006 to June 2017. The language was restricted to English.

Review methods: Abstracts were screened and reviewed against the eligibility criteria (participants' mean age were ≥ 60 with PD, PA interventions, depression as one of outcome variables, and Randomized Control Trail or quasi-experimental design). Two reviewers appraised the quality of the data extracted. The modified Jadad scale assessed the quality of the methodology of the published papers.

Results: The database search yielded 769 abstracts, 11 of which were included in this review and awarded scores ranging from 3 to 8 (Scale scores range from 0 to 8 points, higher scores indicated better quality) by the raters. These 11 studies included 342 patients and executed 17 kinds of physical activity programs. Results of this review show empirical evidence to support the efficacy of physical activity for the population with Parkinson's disease. Aerobic training exercise significantly improved the participants' scores on the Unified Parkinson's Disease Rating Scale, the Beck Depression Inventory, and the Quality of Life of the patients. Qigong improved scores in UPDRS-III and decreased incidences of multiple non-motor symptoms and depression. Furthermore, a balance-training program, such as Tai Chi, can improve postural stability and Quality of Life.

Conclusions: Physical activity may assuage the degeneration of motor skills and depression as well as increase the Quality of Life of Parkinson's disease patients, with aerobic training producing the best results. These findings suggest that physical activity, notably aerobic training, could be a good exercise strategy for patients with Parkinson's disease.

Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Fig 1. Flowchart of studies.
Fig 1. Flowchart of studies.

References

    1. Rao SS, Hofmann LA, Shakil A. Parkinson’s disease: diagnosis and treatment. Am Fam Physician. 2006;74(12):2046–54.
    1. Hsu H-Y, Huang T-T, Weng Y-H, Li C-L, Lu C-S. The Inclination to Depressive Mood and Related Factors among Patients with Parkinson's Disease. Journal of Evidence-Based Nursing. 2007;3(3). doi:
    1. Tagliati M, Chaudhuri K, Pagano G. Prevalence Of Non-Motor Symptoms In Parkinson’s Disease: A Systematic Review With Meta-Analysis (P2. 053). Neurology. 2014;82(10 Supplement):P2. 053.
    1. Dissanayaka NN, Sellbach A, Silburn PA, O'Sullivan JD, Marsh R, Mellick GD. Factors associated with depression in Parkinson's disease. Journal of affective disorders. 2011;132(1–2):82–8. doi:
    1. Pachana NA, Egan SJ, Laidlaw K, Dissanayaka N, Byrne GJ, Brockman S, et al. Clinical issues in the treatment of anxiety and depression in older adults with Parkinson's disease. Movement Disorders. 2013;28(14):1930–4. doi:
    1. Huang T-T, Liu C-B, Tsai Y-H, Chin Y-F, Wong C-H. Physical fitness exercise versus cognitive behavior therapy on reducing the depressive symptoms among community-dwelling elderly adults: A randomized controlled trial. International journal of nursing studies. 2015;2015(52):1542–52. doi:
    1. Caspersen CJ, Powell KE, Christenson GM. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public health reports. 1985;100(2):126–31.
    1. Global strategy on diet, physical activity and health: physical inactivity: a global public health problem [Internet]. 2015. Available from: .
    1. Global Strategy on Diet, Physical Activity and Health. What is moderate-intensity and vigorous-intensity Physical Activity? [Internet]. 2015. Available from: .
    1. ACSM In The News [Internet]. 2011. Available from: .
    1. Kolk NM, King LA. Effects of exercise on mobility in people with Parkinson's disease. Movement Disorders. 2013;28(11):1587–96. doi:
    1. Dietrich A, McDaniel WF. Endocannabinoids and exercise. British Journal of Sports Medicine. 2004;38(5):536–41. doi:
    1. Biddle SJ, Asare M. Physical activity and mental health in children and adolescents: a review of reviews. British journal of sports medicine. 2011;45(11):886–95. doi:
    1. Wipfli B, Landers D, Nagoshi C, Ringenbach S. An examination of serotonin and psychological variables in the relationship between exercise and mental health. Scandinavian Journal of Medicine & Science in Sports. 2011;21(3):474–81. doi:
    1. Park S-H, Han KS, Kang C-B. Effects of exercise programs on depressive symptoms, quality of life, and self-esteem in older people: A systematic review of randomized controlled trials. Applied Nursing Research. 2014;27(4):219–26. doi:
    1. Bridle C, Spanjers K, Patel S, Atherton NM, Lamb SE. Effect of exercise on depression severity in older people: systematic review and meta-analysis of randomised controlled trials. The British Journal of Psychiatry. 2012;201(3):180–5. doi:
    1. Potter R, Ellard D, Rees K, Thorogood M. A systematic review of the effects of physical activity on physical functioning, quality of life and depression in older people with dementia. International journal of geriatric psychiatry. 2011;26(10):1000–11. doi:
    1. Moher D, Liberati A, Tetzlaff J, Altman DG, Group P. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. International journal of surgery. 2010;8(5):336–41. doi:
    1. Olivo SA, Macedo LG, Gadotti IC, Fuentes J, Stanton T, Magee DJ. Scales to assess the quality of randomized controlled trials: a systematic review. Physical therapy. 2008;88(2):156–75. doi:
    1. Greenhalgh T. Assessing the methodological quality of published papers. BMJ: British Medical Journal. 1997;315(7103):305–8.
    1. Oremus M, Wolfson C, Perrault A, Demers L, Momoli F, Moride Y. Interrater reliability of the modified Jadad quality scale for systematic reviews of Alzheimer’s disease drug trials. Dementia and geriatric cognitive disorders. 2001;12(3):232–6.
    1. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJM, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Controlled clinical trials. 1996;17(1):1–12. doi:
    1. Lee N-Y, Lee D-K, Song H-S. Effect of virtual reality dance exercise on the balance, activities of daily living, and depressive disorder status of Parkinson’s disease patients. Journal of physical therapy science. 2015;27(1):145–7. doi:
    1. Altmann LJ, Stegemöller E, Hazamy AA, Wilson JP, Bowers D, Okun MS, et al. Aerobic exercise improves mood, cognition, and language function in parkinson’s disease: results of a controlled study. Journal of the International Neuropsychological Society. 2016;22(9):878–89. doi:
    1. Dashtipour K, Johnson E, Kani C, Kani K, Hadi E, Ghamsary M, et al. Effect of exercise on motor and nonmotor symptoms of Parkinson’s disease. Parkinson’s disease. 2015;2015(586378):1–5. doi:
    1. Khallaf M, Fathy H. Effect of treadmill training on activities of daily living and depression in patients with Parkinson's disease. Middle East Current Psychiatry. 2011;18(3):144–8. doi:
    1. Dereli EE, Yaliman A. Comparison of the effects of a physiotherapist-supervised exercise programme and a self-supervised exercise programme on quality of life in patients with Parkinson’s disease. Clinical rehabilitation. 2010;24(4):352–62. doi:
    1. Sajatovic M, Ridgel AL, Walter EM, Tatsuoka CM, Colón-Zimmermann K, Ramsey RK, et al. A randomized trial of individual versus group-format exercise and self-management in individuals with Parkinson’s disease and comorbid depression. Patient preference and adherence. 2017;11:965–73. doi:
    1. Schmitz‐Hübsch T, Pyfer D, Kielwein K, Fimmers R, Klockgether T, Wüllner U. Qigong exercise for the symptoms of Parkinson's disease: a randomized, controlled pilot study. Movement Disorders. 2006;21(4):543–8. doi:
    1. Tanaka K, de Quadros AC, Santos RF, Stella F, Gobbi LTB, Gobbi S. Benefits of physical exercise on executive functions in older people with Parkinson’s disease. Brain and cognition. 2009;69(2):435–41. doi:
    1. Smania N, Corato E, Tinazzi M, Stanzani C, Fiaschi A, Girardi P, et al. Effect of balance training on postural instability in patients with idiopathic Parkinson’s disease. Neurorehabilitation and Neural Repair. 2010;24(9):826–34. doi:
    1. Cheon S-M, Chae B-K, Sung H-R, Lee GC, Kim JW. The efficacy of exercise programs for Parkinson's disease: Tai Chi versus combined exercise. Journal of Clinical Neurology. 2013;9(4):237–43. doi:
    1. Burini D, Farabollini B, Iacucci S, Rimatori C, Riccardi G, Capecci M, et al. A randomised controlled cross-over trial of aerobic training versus Qigong in advanced Parkinson's disease. Europa medicophysica. 2006;42(3):231–8.
    1. De Lau L, Giesbergen P, De Rijk M, Hofman A, Koudstaal P, Breteler M. Incidence of parkinsonism and Parkinson disease in a general population The Rotterdam Study. Neurology. 2004;63(7):1240–4. doi:
    1. Kadastik-Eerme L, Rosenthal M, Paju T, Muldmaa M, Taba P. Health-related quality of life in Parkinson’s disease: a cross-sectional study focusing on non-motor symptoms. Health and quality of life outcomes. 2015;13(1):83 doi:
    1. Goncalves GB. Using the Nintendo® Wii Fit™ plus platform in the sensorimotor training of freezing of gait in Parkinson’s disease. Arquivos de neuro-psiquiatria. 2013;71(10):828 doi:
    1. Lauhoff P, Murphy N, Doherty C, Horgan NF. A controlled clinical trial investigating the effects of cycle ergometry training on exercise tolerance, balance and quality of life in patients with Parkinson’s disease. Disability and rehabilitation. 2013;35(5):382–7. doi:
    1. Nadeau A, Pourcher E, Corbeil P. Effects of 24 weeks of treadmill training on gait performance in Parkinson disease. Med Sci Sports Exerc. 2014;46(4):645–55. doi:
    1. Pérez CA, Cancela J. Effectiveness of water-based exercise in people living with Parkinson’s disease: a systematic review. European Review of Aging and Physical Activity. 2013;11(2):107–18. doi:
    1. Volpe D, Signorini M, Marchetto A, Lynch T, Morris ME. A comparison of Irish set dancing and exercises for people with Parkinson’s disease: a phase II feasibility study. BMC geriatrics. 2013;13(1):54 doi:
    1. Foulds HJ, Bredin SS, Charlesworth SA, Ivey AC, Warburton DE. Exercise volume and intensity: a dose–response relationship with health benefits. European journal of applied physiology. 2014;114(8):1563–71. doi:

Source: PubMed

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