Delayed reward discounting and addictive behavior: a meta-analysis

James MacKillop, Michael T Amlung, Lauren R Few, Lara A Ray, Lawrence H Sweet, Marcus R Munafò, James MacKillop, Michael T Amlung, Lauren R Few, Lara A Ray, Lawrence H Sweet, Marcus R Munafò

Abstract

Rationale: Delayed reward discounting (DRD) is a behavioral economic index of impulsivity and numerous studies have examined DRD in relation to addictive behavior. To synthesize the findings across the literature, the current review is a meta-analysis of studies comparing DRD between criterion groups exhibiting addictive behavior and control groups.

Objectives: The meta-analysis sought to characterize the overall patterns of findings, systematic variability by sample and study type, and possible small study (publication) bias.

Methods: Literature reviews identified 310 candidate articles from which 46 studies reporting 64 comparisons were identified (total N=56,013).

Results: From the total comparisons identified, a small magnitude effect was evident (d= .15; p< .00001) with very high heterogeneity of effect size. Based on systematic observed differences, large studies assessing DRD with a small number of self-report items were removed and an analysis of 57 comparisons (n=3,329) using equivalent methods and exhibiting acceptable heterogeneity revealed a medium magnitude effect (d= .58; p< .00001). Further analyses revealed significantly larger effect sizes for studies using clinical samples (d= .61) compared with studies using nonclinical samples (d=.45). Indices of small study bias among the various comparisons suggested varying levels of influence by unpublished findings, ranging from minimal to moderate.

Conclusions: These results provide strong evidence of greater DRD in individuals exhibiting addictive behavior in general and particularly in individuals who meet criteria for an addictive disorder. Implications for the assessment of DRD and research priorities are discussed.

Figures

Fig. 1
Fig. 1
Effect sizes (d), standard errors, variances, 95% confidence intervals, Z scores, and statistical significance for comparisons of individuals meeting an addictive behavior criterion to healthy controls in the primary meta-analytic sample (k=57). Overall values follow individual study values. Effect sizes are proportional to sample size comparison. Effect sizes to the right of zero reflect greater (more impulsive) DRD in the criterion group compared with the control group; effect sizes to the left reflect greater DRD in the control group. Effect sizes for which the confidence intervals do not include zero reflect significant differences. Arrows reflect the 95% confidence intervals exceeding an effect size of greater than 2. The study subscripts do not refer to different studies, but different comparisons

Source: PubMed

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