Genetic counselling for schizophrenia in the era of molecular genetics

Abstract

Objective: To review the role of genetic counselling for individuals with psychiatric illnesses.

Method: Using schizophrenia as an example and including updated information about a genetic subtype (22q deletion syndrome), we discuss the value of the genetic counselling process in psychiatry, with support from the literature and our clinical experience.

Results: Genetic counselling, the process through which knowledge about the genetics of illnesses is shared, provides information on the inheritance of illnesses and their recurrence risks; addresses the concerns of patients, their families, and their health care providers; and supports patients and their families dealing with these illnesses. For comprehensive medical management, this service should be available to all individuals with schizophrenia and their families.

Conclusions: New findings in the genetics of psychiatric illness may have important clinical implications for patients and their families.

Figures

Figure 1

Definition of genetic counselling: American Society of Human Genetics: 1975 Ad Hoc Committee on Genetic Counselling