Converting Cold into Hot Tumors by Combining Immunotherapies

John B A G Haanen, John B A G Haanen

Abstract

In a small phase Ib study in this issue of Cell, Ribas et al. report that the combination of intralesional injection of a modified human herpes simplex virus and systemic anti-PD-1 treatment resulted in a 62% response rate in patients with metastatic melanoma, accompanied by enhanced T cell infiltration in virus-injected lesions.

Copyright © 2017 Elsevier Inc. All rights reserved.

Source: PubMed

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