Chemical peels for acne and acne scars in asians: evidence based review

Evangeline B Handog, Maria Suzanne L Datuin, Ivan A Singzon, Evangeline B Handog, Maria Suzanne L Datuin, Ivan A Singzon

Abstract

Chemical peeling is a widely used procedure in the management of acne and acne scars, but there are very few studies on Asian populations who are more prone to develop hyper pigmentation. This article aims to summarize and evaluate the existing studies on the role of chemical peels in the treatment of acne and acne scars among Asians. An online search was conducted to identify prospective studies published in English that evaluated the use of chemical peels in active acne and acne scars in Asian populations. There were six studies for acne and eight studies for acne scars that were identified using our search parameters. Most were single-centre, open label and with small sample sizes. Acne severity was not uniformly reported and the objective outcome measures of some studies were not explicitly reported as well. The general trend of the results of the studies support the safety and efficacy of chemical peels for acne and acne scars including those of darker skin types. The existing studies support the use of chemical peels in the treatment of acne and acne scars in Asians. Further clinical trials with better study design and more subjects are needed to further establish the role of chemical peels in Asian acne patients.

Keywords: Acne; acne scars; asians; chemical peel; glycolic acid; salicylic acid; trichloroacetic acid.

Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Kessler E, Flanagan K, Chia C, Rogers C, Glaser DA. Comparison of alpha- and beta-hydroxy acid chemical peels in the treatment of mild to moderately severe facial acne vulgaris. Dermatol Surg. 2008;34:45–50.
    1. Taub AF. Procedural treatments for acne vulgaris. Dermatol Surg. 2007;33:1005–26.
    1. Hashimoto Y, Suga Y, Mizuno Y, Hasegawa T, Matsuba S, Ikeda S, et al. Salicylic acid peels in polyethylene glycol vehicle for the treatment of comedogenic acne in Japanese patients. Dermatol Surg. 2008;34:276–9.
    1. Kligman D, Kligman AM. Salicylic acid as a peeling agent for the treatment of acne. Cosmetic Dermatol. 1997;10:44–7.
    1. Kim SW, Moon SE, Kim JA, Eun HC. Glycolic acid versus Jessner's solution: Which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. Dermatol Surg. 1999;25:270–3.
    1. Baumann L, Saghari S. Chemical Peels. In: Baumann L, editor. Cosmetic Dermatology. 2nd ed. New York: McGraw-Hill; 2002. pp. 148–60.
    1. Dréno B, Fischer TC, Perosino E, Poli F, Viera MS, Rendon MI, et al. Expert opinion: Efficacy of superficial chemical peels in active acne management--what can we learn from the literature today? Evidence-based recommendations. J Eur Acad Dermatol Venereol. 2011;25:695–704.
    1. Garg VK, Sinha S, Sarkar R. Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyper pigmentation: A comparative study. Dermatol Surg. 2009;35:59–65.
    1. Goh CL, Akarapanth R. Epidemiology of skin disease among children in a referral skin clinic in Singapore. Pediatr Dermatol. 1994;11:125–8.
    1. Yeung CK, Teo LH, Xiang LH, Chan HH. A community-based epidemiological study of acne vulgaris in Hong Kong adolescents. Acta Derm Venereol. 2002;82:104–7.
    1. Handog EB, Macarayo MJ, Gabriel MT. Acne scars in Asian patients. In: Tosti A, De Padova M, Beer K, editors. Acne scars: Classification and treatment (Series in dermatological treatment) 1st ed. UK: Informa Healthcare; 2009. p. 90.
    1. Shah SK, Bhanusali DG, Sachdev A, Geria AN, Alexis AF. A survey of skin conditions and concerns in South Asian Americans: A community-based study. J Drugs Dermatol. 2011;10:524–8.
    1. Kim IH. Salicylic acid peel (Acne peel) Hong Kong J Dermatol Venereol. 2005;13:83–5.
    1. Dainichi T, Ueda S, Imayama S, Furue M. Excellent clinical results with a new preparation for chemical peeling in acne: 30% salicylic acid in polyethylene glycol vehicle. Dermatol Surg. 2008;34:891–9.
    1. Bhardwaj D, Khunger N. An assessment of the efficacy and safety of CROSS Technique with 100% TCA in the management of ice pick acne scars. J Cutan Aesthet Surg. 2010;3:93–6.
    1. Lee JB, Chung WG, Kwahck H, Lee KH. Focal treatment of acne scars with trichloroacetic acid: Chemical reconstruction of skin scars method. Dermatol Surg. 2002;28:1017–21.
    1. Goodman G. Treatment of acne scarring. Int J Dermatol. 2011;50:1179–94.
    1. Lee HS, Kim IH. Salicylic acid peels for the treatment of acne vulgaris in Asian patients. Dermatol Surg. 2003;29:1196–9. discussion 9.
    1. Ahn HH, Kim IH. Whitening effect of salicylic acid peels in Asian patients. Dermatol Surg. 2006;32:372–5. discussion 5.
    1. Lai KW, Mercurio MG. Update on the treatment of acne vulgaris. J Clin Outcomes Manag. 2009;16:115–26.
    1. Berger R. Initial studies show salicylic acid promising as anti-aging preparation. Cosmet Dermatol. 1997;10:31–2.
    1. Taenaka Y, Hayashi N, Takeda M, Ashikaga S, Kawashima M. Glycolic acid chemical peeling improves inflammatory acne eruptions through its inhibitory and bactericidal effect of Proprionibacterium acnes. J Dermatol. 2012;39:350–4.
    1. Atzori L, Brundu MA, Orru A, Biggio P. Glycolic acid peeling in the treatment of acne. J Eur Acad Dermatol Venereol. 1999;12:119–22.
    1. Rubin MG. Superficial and medium depth. 1st ed. Philadelphia, PA: JB Lippincott Company; 1995. Manual of chemical peels.
    1. McCulloch EG, Langsdon PR, Maloney BP. Chemical peel with phenol. In: Roenigk RK, Roenigk HH, editors. Dermatologic Surgery, Principles and Practice. 2nd ed. UK, Oxford: Marcel Decker Ltd; 1996. pp. 1147–60.
    1. Al-Waiz MM, Al-Sharqi AI. Medium-depth chemical peels in the treatment of acne scars in dark-skinned individuals. Dermatol Surg. 2002;28:383–7.
    1. Park JH, Choi YD, Kim SW, Kim YC, Park SW. Effectiveness of modified phenol peel (Exoderm) on facial wrinkles, acne scars and other skin problems in Asian patients. J Dermatol. 2007;34:17–24.
    1. Deprez P. Textbook of chemical peels: Superficial, medium and deep peels in cosmetic practice. London: Informa Healthcare; 2007. p. 206.
    1. Wang CM, Huang CL, Hu CT, Chan HL. The effect of glycolic acid on the treatment of acne in Asian skin. Dermatol Surg. 1997;23:23–9.
    1. Khunger N, Bhardwaj D, Khunger M. Evaluation of CROSS technique with 100% TCA in the management of ice pick acne scars in darker skin types. J Cosmet Dermatol. 2011;10:51–7.
    1. Sachdeva S. Lactic acid peeling in superficial acne scarring in Indian skin. J Cosmet Dermatol. 2010;9:246–8.
    1. Sharad J. Combination of micro needling and glycolic acid peels for the treatment of acne scars in dark skin. J Cosmet Dermatol. 2011;10:317–23.
    1. Yoon ES, Ahn DS. Report of phenol peel for Asians. Plast Reconstr Surg. 1999;103:207–14. discussion 215-7.

Source: PubMed

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