Falciparum malaria cured by quinine followed by sulfadoxine-pyrimethamine

A P Hall, E B Doberstyn, V Mettaprakong, P Sonkom, A P Hall, E B Doberstyn, V Mettaprakong, P Sonkom

Abstract

Quinine (at least four doses given at intervals of eight to 12 hours) followed by a single dose of sulfadoxine-pyrimethamine (Fansidar) is the most effective treatment of chloroquine-resistant falciparum malaria. This regimen cured 96% of patients (302 out of 314) with an average initial parasite count of 90 X 10-9/1.

References

    1. Br Med J. 1964 Dec 5;2(5422):1439-40
    1. Am J Trop Med Hyg. 1959 Jan;8(1):60-2
    1. Southeast Asian J Trop Med Public Health. 1974 Sep;5(3):413-6
    1. Ann Intern Med. 1970 Aug;73(2):295-306
    1. Br Med J. 1974 Apr 27;2(5912):206-8
    1. Clin Pharmacol Ther. 1973 Jul-Aug;14(4):580-5
    1. Adv Pharmacol Chemother. 1970;8:121-47
    1. Am J Trop Med Hyg. 1966 Nov;15(6):823-9
    1. Clin Pharmacol Ther. 1969 Jan-Feb;10(1):85-91
    1. Chemotherapy. 1970;15(6):337-55
    1. Am J Trop Med Hyg. 1968 May;17(3):465-73
    1. JAMA. 1967 Jan 16;199(3):173-7
    1. JAMA. 1966 Nov 28;198(9):975-80

Source: PubMed

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