Polyetheretherketone cages alone with allograft for three-level anterior cervical fusion

Hong Liu, Avraam Ploumis, Chunde Li, Xiaodong Yi, Hong Li, Hong Liu, Avraam Ploumis, Chunde Li, Xiaodong Yi, Hong Li

Abstract

A total of 25 consecutive patients suffering from degenerative cervical disc disease who underwent three-level anterior cervical discectomy and fusion (ACDF) including polyetheretherketone (PEEK) cages packed with allograft were followed up for at least two years. The fusion rate reached 72% (18/25), and asymptomatic pseudarthrosis was seen in 6 patients but without mobility on flexion-extension radiographs, and revision surgery was not needed. Cage subsidence occurred at one level (C67), but it was not progressive, and reoperation was not necessary. A significant increase (P < 0.001) in fused segment angle (FSA) and fused segment height (FSH) was observed postoperatively. Similarly, a significant clinical improvement (P < 0.001) was demonstrated postoperatively in terms of Japanese Orthopedic Association (JOA) score and visual analog scales (VASs) score. PEEK cages alone with allograft proved to be a safe and effective surgical option in the treatment of three-level degenerative cervical disc disease. Although the fusion rate was not high, this technique may offer improvement of symptomatology and maintenance of cervical spine's sagittal profile.

Figures

Figure 1
Figure 1
(a) Preoperative radiograph showing C3–C6 segment degeneration. (b) Preoperative sagittal T2W1 MR image revealed C34, C45, and C56 spinal cord compression. (c) Postoperative plain radiographs demonstrating adequate cervical lordosis and no cage subsidence 3 months (1) and one year (2) after ACDF. (d) Sagittal T2W1 MR image showing no spinal cord compression one year after ACDF. (e) Postoperative sagittal reconstruction CT image demonstrating C3–C6 fusion and no lucency between cages and endplates at one year postoperatively.

References

    1. Zdeblick TA, Phillips FM. Interbody cage devices. Spine. 2003;28(15):S2–S7.
    1. Moreland DB, Asch HL, Clabeaux DE, et al. Anterior cervical discectomy and fusion with implantable titanium cage: initial impressions, patient outcomes and comparison to fusion with allograft. Spine Journal. 2004;4(2):184–191.
    1. Vavruch L, Hedlund R, Javid D, Leszniewski W, Shalabi A. A prospective randomized comparison between the Cloward procedure and a carbon fiber cage in the cervical spine: a clinical and radiologic study. Spine. 2002;27(16):1694–1701.
    1. Fujibayashi S, Neo M, Nakamura T. Stand-alone interbody cage versus anterior cervical plate for treatment of cervical disc herniation: sequential changes in cage subsidence. Journal of Clinical Neuroscience. 2008;15(9):1017–1022.
    1. Hwang SL, Lin CL, Lieu AS, et al. Three-level and four-level anterior cervical discectomies and titanium cage-augmented fusion with and without plate fixation. Journal of Neurosurgery. 2004;1(2):160–167.
    1. Song KJ, Taghavi CE, Lee KB, Song JH, Eun JP. The efficacy of plate construct augmentation versus cage alone in anterior cervical fusion. Spine. 2009;34(26):2886–2892.
    1. Bertalanffy H, Eggert HR. Complications of anterior cervical discectomy without fusion in 450 consecutive patients. Acta Neurochirurgica. 1989;99(1-2):41–50.
    1. Beutler WJ, Sweeney CA, Connolly PJ. Recurrent laryngeal nerve injury with anterior cervical spine surgery: risk with laterality of surgical approach. Spine. 2001;26(12):1337–1342.
    1. Gaudinez RF, English GM, Gebhard JS, Brugman JL, Donaldson DH, Brown CW. Esophageal perforations after anterior cervical surgery. Journal of Spinal Disorders. 2000;13(1):77–84.
    1. Lowery GL, Swank ML, McDonough RF. Surgical revision for failed anterior cervical fusions: articular pillar plating or anterior revision? Spine. 1995;20(22):2436–2441.
    1. Cho DY, Lee WY, Sheu PC. Treatment of multilevel cervical fusion with cages. Surgical Neurology. 2004;62(5):378–385.
    1. Chou YC, Chen DC, Hsieh WA, et al. Efficacy of anterior cervical fusion: comparison of titanium cages, polyetheretherketone (PEEK) cages and autogenous bone grafts. Journal of Clinical Neuroscience. 2008;15(11):1240–1245.
    1. Demircan MN, Kutlay AM, Colak A, et al. Multilevel cervical fusion without plates, screws or autogenous iliac crest bone graft. Journal of Clinical Neuroscience. 2007;14(8):723–728.
    1. Hee HT, Kundnani V. Rationale for use of polyetheretherketone polymer interbody cage device in cervical spine surgery. Spine Journal. 2010;10(1):66–69.
    1. Kulkarni AG, Hee HT, Wong HK. Solis cage (PEEK) for anterior cervical fusion: preliminary radiological results with emphasis on fusion and subsidence. Spine Journal. 2007;7(2):205–209.
    1. Hirabayashi K, Watanabe K, Wakano K. Expansive open-door laminoplasty for cervical spinal stenotic myelopathy. Spine. 1983;8(7):693–699.
    1. Cannada LK, Scherping SC, Yoo JU, Jones PK, Emery SE. Pseudoarthrosis of the cervical spine: a comparison of radiographic diagnostic measures. Spine. 2003;28(1):46–51.
    1. Ploumis A, Mehbod A, Garvey T, Gilbert T, Transfeldt E, Wood K. Prospective assessment of cervical fusion status: plain radiographs versus CT-scan. Acta Orthopaedica Belgica. 2006;72(3):342–346.
    1. Tribus CB, Corteen DP, Zdeblick TA. The efficacy of anterior cervical plating in the management of symptomatic pseudoarthrosis of the cervical spine. Spine. 1999;24(9):860–864.
    1. Shono Y, McAfee PC, Cunningham BW, Brantigan JW. A biomechanical analysis of decompression and reconstruction methods in the cervical spine. Emphasis on a carbon-fiber-composite cage. Journal of Bone and Joint Surgery Series A. 1993;75(11):1674–1684.

Source: PubMed

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