Polyetheretherketone cages alone with allograft for three-level anterior cervical fusion
Hong Liu, Avraam Ploumis, Chunde Li, Xiaodong Yi, Hong Li, Hong Liu, Avraam Ploumis, Chunde Li, Xiaodong Yi, Hong Li
Abstract
A total of 25 consecutive patients suffering from degenerative cervical disc disease who underwent three-level anterior cervical discectomy and fusion (ACDF) including polyetheretherketone (PEEK) cages packed with allograft were followed up for at least two years. The fusion rate reached 72% (18/25), and asymptomatic pseudarthrosis was seen in 6 patients but without mobility on flexion-extension radiographs, and revision surgery was not needed. Cage subsidence occurred at one level (C67), but it was not progressive, and reoperation was not necessary. A significant increase (P < 0.001) in fused segment angle (FSA) and fused segment height (FSH) was observed postoperatively. Similarly, a significant clinical improvement (P < 0.001) was demonstrated postoperatively in terms of Japanese Orthopedic Association (JOA) score and visual analog scales (VASs) score. PEEK cages alone with allograft proved to be a safe and effective surgical option in the treatment of three-level degenerative cervical disc disease. Although the fusion rate was not high, this technique may offer improvement of symptomatology and maintenance of cervical spine's sagittal profile.
Figures
References
- Zdeblick TA, Phillips FM. Interbody cage devices. Spine. 2003;28(15):S2–S7.
- Moreland DB, Asch HL, Clabeaux DE, et al. Anterior cervical discectomy and fusion with implantable titanium cage: initial impressions, patient outcomes and comparison to fusion with allograft. Spine Journal. 2004;4(2):184–191.
- Vavruch L, Hedlund R, Javid D, Leszniewski W, Shalabi A. A prospective randomized comparison between the Cloward procedure and a carbon fiber cage in the cervical spine: a clinical and radiologic study. Spine. 2002;27(16):1694–1701.
- Fujibayashi S, Neo M, Nakamura T. Stand-alone interbody cage versus anterior cervical plate for treatment of cervical disc herniation: sequential changes in cage subsidence. Journal of Clinical Neuroscience. 2008;15(9):1017–1022.
- Hwang SL, Lin CL, Lieu AS, et al. Three-level and four-level anterior cervical discectomies and titanium cage-augmented fusion with and without plate fixation. Journal of Neurosurgery. 2004;1(2):160–167.
- Song KJ, Taghavi CE, Lee KB, Song JH, Eun JP. The efficacy of plate construct augmentation versus cage alone in anterior cervical fusion. Spine. 2009;34(26):2886–2892.
- Bertalanffy H, Eggert HR. Complications of anterior cervical discectomy without fusion in 450 consecutive patients. Acta Neurochirurgica. 1989;99(1-2):41–50.
- Beutler WJ, Sweeney CA, Connolly PJ. Recurrent laryngeal nerve injury with anterior cervical spine surgery: risk with laterality of surgical approach. Spine. 2001;26(12):1337–1342.
- Gaudinez RF, English GM, Gebhard JS, Brugman JL, Donaldson DH, Brown CW. Esophageal perforations after anterior cervical surgery. Journal of Spinal Disorders. 2000;13(1):77–84.
- Lowery GL, Swank ML, McDonough RF. Surgical revision for failed anterior cervical fusions: articular pillar plating or anterior revision? Spine. 1995;20(22):2436–2441.
- Cho DY, Lee WY, Sheu PC. Treatment of multilevel cervical fusion with cages. Surgical Neurology. 2004;62(5):378–385.
- Chou YC, Chen DC, Hsieh WA, et al. Efficacy of anterior cervical fusion: comparison of titanium cages, polyetheretherketone (PEEK) cages and autogenous bone grafts. Journal of Clinical Neuroscience. 2008;15(11):1240–1245.
- Demircan MN, Kutlay AM, Colak A, et al. Multilevel cervical fusion without plates, screws or autogenous iliac crest bone graft. Journal of Clinical Neuroscience. 2007;14(8):723–728.
- Hee HT, Kundnani V. Rationale for use of polyetheretherketone polymer interbody cage device in cervical spine surgery. Spine Journal. 2010;10(1):66–69.
- Kulkarni AG, Hee HT, Wong HK. Solis cage (PEEK) for anterior cervical fusion: preliminary radiological results with emphasis on fusion and subsidence. Spine Journal. 2007;7(2):205–209.
- Hirabayashi K, Watanabe K, Wakano K. Expansive open-door laminoplasty for cervical spinal stenotic myelopathy. Spine. 1983;8(7):693–699.
- Cannada LK, Scherping SC, Yoo JU, Jones PK, Emery SE. Pseudoarthrosis of the cervical spine: a comparison of radiographic diagnostic measures. Spine. 2003;28(1):46–51.
- Ploumis A, Mehbod A, Garvey T, Gilbert T, Transfeldt E, Wood K. Prospective assessment of cervical fusion status: plain radiographs versus CT-scan. Acta Orthopaedica Belgica. 2006;72(3):342–346.
- Tribus CB, Corteen DP, Zdeblick TA. The efficacy of anterior cervical plating in the management of symptomatic pseudoarthrosis of the cervical spine. Spine. 1999;24(9):860–864.
- Shono Y, McAfee PC, Cunningham BW, Brantigan JW. A biomechanical analysis of decompression and reconstruction methods in the cervical spine. Emphasis on a carbon-fiber-composite cage. Journal of Bone and Joint Surgery Series A. 1993;75(11):1674–1684.
Source: PubMed