Example of the cross-wavelet power (above left) and wavelet transform coherence (above right) for simulated data (bottom). The simulated data consist of negatively-correlated sinusoids with piecewise frequency content (f = 1/16 Hz for 0
Figure 3
Wavelet transform coherence between the…
Figure 3
Wavelet transform coherence between the PCC and 3 of its anticorrelated ROIs, shown…
Figure 3 Wavelet transform coherence between the PCC and 3 of its anticorrelated ROIs, shown for 6 subjects: (top row) right SMG, (middle row) right insula, and (bottom row) right DLPFC. For each WTC map, time is on the x-axis and scale (Fourier period) is on the y-axis. Maps have been thresholded to include only regions that were significant at 95% confidence based on Monte Carlo tests. Colors indicate ranges of the wavelet coherence phase. A phase difference of 0 indicates positive correlation; π indicates negative correlation; π/2 indicates that the PCC ROI leads the anticorrelated ROI; −π/2 indicates that the anticorrelated ROI leads the PCC ROI. Regions of insignificant coherence appear in dark blue, and areas inside the cone of influence are in purple.
Figure 4
Wavelet transform coherence between the…
Figure 4
Wavelet transform coherence between the PCC and default-mode ROIs, shown for 6 subjects:…
Figure 4 Wavelet transform coherence between the PCC and default-mode ROIs, shown for 6 subjects: (top row) MPFC, (middle row) right angular gyrus, (bottom row) left angular gyrus. For further detail, please refer to the caption of Fig. 3.
Figure 5
Significance of temporal variability in…
Figure 5
Significance of temporal variability in the wavelet transform coherence. Each plot shows the…
Figure 5 Significance of temporal variability in the wavelet transform coherence. Each plot shows the number of subjects for which the variance in the WTC between the PCC and the indicated ROI exceeded the 90% (blue) and 95% (red) confidence levels, for each wavelet scale (Fourier period).
Figure 6
Time-averaged coherence (see Eq. 4),…
Figure 6
Time-averaged coherence (see Eq. 4), shown for default-mode (top row) and anticorrelated (middle…
Figure 6 Time-averaged coherence (see Eq. 4), shown for default-mode (top row) and anticorrelated (middle and bottom rows) ROIs. Thick lines represent the mean across subjects (N=12), and error bars represent standard error.
Figure 7
Percentage of the total significant…
Figure 7
Percentage of the total significant coherence occurring within each phase range (φ±π/4), within…
Figure 7 Percentage of the total significant coherence occurring within each phase range (φ±π/4), within each of 5 different frequency bands. Lines and error bars represent the mean±SD, respectively, across the 3 DMN ROIs (left) and 6 anticorrelated ROIs (right).
Figure 8
(A) WTC analysis and (B)…
Figure 8
(A) WTC analysis and (B) time-averaged coherence between the PCC ROI and voxels…
Figure 8 (A) WTC analysis and (B) time-averaged coherence between the PCC ROI and voxels in the MPFC having an overall correlation coefficient with the same approximate SNR as the anticorrelated ROIs in the actual data (for the instance shown here, r = 0.35±0.03 (mean±SD across subjects)). For the time-averaged coherence, error bars indicate the standard error of the mean over 50 iterations.
Figure 9
(A) Variability (standard deviation) over…
Figure 9
(A) Variability (standard deviation) over the sequence of 2-min sliding-window correlation coefficients, averaged…
Figure 9 (A) Variability (standard deviation) over the sequence of 2-min sliding-window correlation coefficients, averaged across all 12 subjects. Five ROIs chosen for further analysis are labeled. (B) t-maps of positive and negative correlations with the PCC (red and blue, respectively, and thresholded identically to Fig. 1), superimposed for anatomical comparison with regions of high variability (SD>0.18; magenta). (C) The intersection of group-level seeded correlation maps (computed across all time points in the scan) using ROIs 1, 2, and 3 as seed regions (green overlay), and using ROIs 4 and 5 as seed regions (cyan overlay). The slice location (z, mm) appears in white numerals and also applies to parts (A) and (B).
Figure 10
Range of sliding-window correlation values…
Figure 10
Range of sliding-window correlation values for ROIs 1–5 (Fig. 9A), for window sizes…
Figure 10 Range of sliding-window correlation values for ROIs 1–5 (Fig. 9A), for window sizes of 2 min (top row) and 4 min (bottom row). Vertical lines indicate the minimum and maximum values of the windowed correlation coefficient across the scan, and the dot on each bar indicates the mean.
Figure 11
Group average (N=12) of Fisher…
Figure 11
Group average (N=12) of Fisher z -transformed correlation coefficients between 5 ROIs (Fig.…
Figure 11 Group average (N=12) of Fisher z-transformed correlation coefficients between 5 ROIs (Fig. 9A) whose correlation with the PCC was highly variable over time. High mutual correlation was observed between ROIs 1–3, and between ROIs 4–5.
Figure 12
(Top row) Time-averaged coherence for…
Figure 12
(Top row) Time-averaged coherence for for the 5 ROIs indicated in Fig. 9A.…
Figure 12 (Top row) Time-averaged coherence for for the 5 ROIs indicated in Fig. 9A. Thick lines represent the mean across subjects (N=12), and error bars represent standard error. (Bottom row) Histograms of the number of subjects for which the variance in the WTC between the PCC and the indicated ROI exceeded the 90% (blue) and 95% (red) confidence levels, for each wavelet scale (Fourier period).
Figure 13
Raw time series and sliding-window…
Figure 13
Raw time series and sliding-window correlation coefficients between the PCC and (A) ROI5…
Figure 13 Raw time series and sliding-window correlation coefficients between the PCC and (A) ROI5 and (B) ROI2, shown for one subject (Subject 1). Sliding-window correlation coefficients are plotted at the time point corresponding to the center of its associated window.
Figure 14
Negative correlations with the PCC…
Figure 14
Negative correlations with the PCC across two successive 7-min segments of resting-state data,…
Figure 14 Negative correlations with the PCC across two successive 7-min segments of resting-state data, shown for one subject. (A) First 7 min, (B) second 7 min. Intensity values represent correlation coefficient (color scale is 0.08
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