Docetaxel, Carboplatin, Trastuzumab och Pertuzumab med eller utan östrogenbrist vid behandling av patienter med hormonreceptorpositiv, HER2-positiv operabel eller lokalt avancerad bröstcancer
15 september 2026 uppdaterad av: National Cancer Institute (NCI)
En randomiserad fas III-studie som utvärderar patologiska fullständiga svarsfrekvenser hos patienter med hormonreceptorpositiv, HER2-positiv, stor operabel och lokalt avancerad bröstcancer behandlade med neoadjuvant terapi av docetaxel, karboplatin, trastuzumab och pertuzumab (TCHP) med deprivation (TCHP)
This randomized phase III trial studies docetaxel, carboplatin, trastuzumab, and pertuzumab with estrogen deprivation to see how they work compared to docetaxel, carboplatin, trastuzumab, and pertuzumab without estrogen deprivation in treating patients with hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-positive breast cancer that is operable or has spread from where it started to nearby tissue or lymph nodes (locally advanced). Drugs used in chemotherapy, such as docetaxel, carboplatin, trastuzumab, and pertuzumab, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Estrogen can cause the growth of breast cancer cells. Hormone therapy using goserelin acetate and aromatase inhibition therapy may fight breast cancer by blocking the use of estrogen by the tumor cells. Radiation therapy uses high energy x rays to kill tumor cells. Giving combination chemotherapy and radiation therapy with or without hormone therapy may be an effective treatment for hormone receptor-positive, HER2-positive, operable or locally advanced breast cancer.
Studieöversikt
Status
Avslutad
Betingelser
Intervention / Behandling
- Läkemedel: Carboplatin
- Biologisk: Trastuzumab
- Övrig: Laboratory Biomarker Analysis
- Övrig: Quality-of-Life Assessment
- Läkemedel: Docetaxel
- Övrig: Cytology Specimen Collection Procedure
- Biologisk: Pertuzumab
- Procedur: Therapeutic Conventional Surgery
- Strålning: Whole Breast Irradiation
- Läkemedel: Aromatase Inhibition Therapy
- Läkemedel: Goserelin Acetate
Detaljerad beskrivning
PRIMARY OBJECTIVES:
I. To determine whether the addition of estrogen deprivation to neoadjuvant therapy consisting of therapy of docetaxel, carboplatin, trastuzumab, and pertuzumab (TCHP) yields a greater rate of pathologic complete response (pCR) (breast and nodes) than TCHP alone when administered to women with operable, hormone receptor-positive, HER2-positive breast cancer.
SECONDARY OBJECTIVES:
I. To determine whether the addition of estrogen deprivation to neoadjuvant therapy consisting of TCHP will increase the pCR rate in the breast compared to TCHP alone when administered to women with operable, hormone receptor-positive, HER2-positive breast cancer.
II. To determine whether the addition of estrogen deprivation to neoadjuvant therapy consisting of TCHP improves recurrence-free interval (RFI) in women with operable, hormone receptor-positive, HER2-positive breast cancer.
III. To determine whether the addition of estrogen deprivation to neoadjuvant therapy consisting of TCHP improves overall survival (OS) in women with operable, hormone receptor-positive, HER2-positive breast cancer.
IV. To compare the rates of second primary invasive cancer by treatment arm. V. Assessment of patterns of pCR, RFI, and OS by menopausal status. VI. To evaluate the cardiac toxicity associated with each of the regimens. VII. To compare the effect of adding estrogen deprivation to neoadjuvant therapy on endocrine-related symptoms in all patients by treatment arm.
VIII. To compare the effect of adding estrogen deprivation to neoadjuvant therapy on vasomotor symptoms, musculoskeletal, and vaginal complaints as well as quality of life.
IX. To determine a relationship between pCR and a potential mechanism of resistance/sensitivity in hormone receptor-positive, HER2-positive tumors.
X. To evaluate tumor infiltrating lymphocytes (TILs) and immune biomarkers as predictors of pCR.
XI. To study early changes in TILs and other immune biomarkers in response to TCHP.
OUTLINE: Patients are randomized to 1 of 2 treatments arms.
NEOADJUVANT:
ARM I: Patients receive docetaxel intravenously (IV) over 60 minutes, carboplatin IV over 30-60 minutes, trastuzumab IV over 30-90 minutes, and pertuzumab IV over 30-60 on day 1. Treatment repeats every 21 days for up to 6 courses in the absence of disease progression or unacceptable toxicity. Patients enrolled after Amendment #4 undergo 2 core biopsies prior to course 3 of treatment.
ARM II: All patients receive docetaxel, carboplatin, trastuzumab, and pertuzumab as in arm I. Premenopausal patients also receive goserelin acetate subcutaneously (SC) every 28 days until surgery and aromatase inhibition therapy at the investigator's discretion daily until 1 day before surgery. Postmenopausal patients receive aromatase inhibition therapy at the investigator's discretion daily until 1 day before surgery. Patients enrolled after Amendment #4 undergo 2 core biopsies prior to course 3 of treatment.
SURGERY: Patients undergo lumpectomy or mastectomy.
RADIATION: Patients undergo whole breast irradiation within 8 weeks following surgery.
ADJUVANT: Patients receive trastuzumab IV over 30-60 minutes every 21 days for up to 1 year.
After completion of study treatment, patients are followed up every 6, 9, 12, and 18 months for 5 years.
Studietyp
Interventionell
Inskrivning (Faktisk)
315
Fas
- Fas 3
Kontakter och platser
Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.
Studieorter
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Alaska
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Fairbanks, Alaska, Förenta staterna, 99701
- Fairbanks Memorial Hospital
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Arkansas
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Hot Springs, Arkansas, Förenta staterna, 71913
- CHI Saint Vincent Cancer Center Hot Springs
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California
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Anaheim, California, Förenta staterna, 92806
- Kaiser Permanente-Anaheim
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Antioch, California, Förenta staterna, 94531
- Kaiser Permanente-Deer Valley Medical Center
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Arroyo Grande, California, Förenta staterna, 93420
- PCR Oncology
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Auburn, California, Förenta staterna, 95602
- Sutter Auburn Faith Hospital
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Auburn, California, Förenta staterna, 95603
- Sutter Cancer Centers Radiation Oncology Services-Auburn
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Baldwin Park, California, Förenta staterna, 91706
- Kaiser Permanente-Baldwin Park
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Bellflower, California, Förenta staterna, 90706
- Kaiser Permanente-Bellflower
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Berkeley, California, Förenta staterna, 94704
- Alta Bates Summit Medical Center-Herrick Campus
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Burlingame, California, Förenta staterna, 94010
- Mills-Peninsula Medical Center
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Cameron Park, California, Förenta staterna, 95682
- Sutter Cancer Centers Radiation Oncology Services-Cameron Park
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Castro Valley, California, Förenta staterna, 94546
- Eden Hospital Medical Center
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Castro Valley, California, Förenta staterna, 94546
- East Bay Radiation Oncology Center
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Davis, California, Förenta staterna, 95616
- Sutter Davis Hospital
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Dublin, California, Förenta staterna, 94568
- Epic Care-Dublin
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Emeryville, California, Förenta staterna, 94608
- Bay Area Breast Surgeons Inc
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Emeryville, California, Förenta staterna, 94608
- Epic Care Partners in Cancer Care
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Fontana, California, Förenta staterna, 92335
- Kaiser Permanente-Fontana
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Fremont, California, Förenta staterna, 94538
- Kaiser Permanente-Fremont
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Fresno, California, Förenta staterna, 93720
- Kaiser Permanente-Fresno
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Harbor City, California, Förenta staterna, 90710
- Kaiser Permanente South Bay
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Irvine, California, Förenta staterna, 92618
- Kaiser Permanente-Irvine
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Loma Linda, California, Förenta staterna, 92354
- Loma Linda University Medical Center
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Los Angeles, California, Förenta staterna, 90027
- Kaiser Permanente Los Angeles Medical Center
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Los Angeles, California, Förenta staterna, 90048
- Cedars Sinai Medical Center
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Los Angeles, California, Förenta staterna, 90034
- Kaiser Permanente West Los Angeles
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Martinez, California, Förenta staterna, 94553-3156
- Contra Costa Regional Medical Center
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Modesto, California, Förenta staterna, 95355
- Memorial Medical Center
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Modesto, California, Förenta staterna, 95356
- Kaiser Permanente-Modesto
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Mountain View, California, Förenta staterna, 94040
- El Camino Hospital
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Mountain View, California, Förenta staterna, 94040
- Palo Alto Medical Foundation-Camino Division
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Mountain View, California, Förenta staterna, 94040
- Palo Alto Medical Foundation-Gynecologic Oncology
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Novato, California, Förenta staterna, 94945
- Sutter Cancer Research Consortium
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Oakland, California, Förenta staterna, 94611
- Kaiser Permanente-Oakland
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Oakland, California, Förenta staterna, 94609
- Alta Bates Summit Medical Center - Summit Campus
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Oakland, California, Förenta staterna, 94609
- Hematology and Oncology Associates-Oakland
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Oakland, California, Förenta staterna, 94609
- Bay Area Tumor Institute
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Oakland, California, Förenta staterna, 94602
- Wilma Chan Highland Hospital
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Orange, California, Förenta staterna, 92868
- Saint Joseph Hospital - Orange
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Palo Alto, California, Förenta staterna, 94304
- Stanford Cancer Institute Palo Alto
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Palo Alto, California, Förenta staterna, 94301
- Palo Alto Medical Foundation Health Care
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Panorama City, California, Förenta staterna, 91402
- Kaiser Permanente - Panorama City
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Pleasanton, California, Förenta staterna, 94588
- Valley Medical Oncology Consultants
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Redwood City, California, Förenta staterna, 94063
- Kaiser Permanente-Redwood City
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Richmond, California, Förenta staterna, 94801
- Kaiser Permanente-Richmond
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Riverside, California, Förenta staterna, 92505
- Kaiser Permanente-Riverside
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Roseville, California, Förenta staterna, 95661
- Kaiser Permanente-Roseville
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Roseville, California, Förenta staterna, 95661
- Sutter Cancer Centers Radiation Oncology Services-Roseville
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Roseville, California, Förenta staterna, 95661
- Sutter Roseville Medical Center
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Sacramento, California, Förenta staterna, 95816
- Sutter Medical Center Sacramento
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Sacramento, California, Förenta staterna, 95823
- Kaiser Permanente-South Sacramento
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Sacramento, California, Förenta staterna, 95825
- Kaiser Permanente Sacramento Medical Center
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San Diego, California, Förenta staterna, 92120
- Kaiser Permanente-San Diego Zion
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San Diego, California, Förenta staterna, 92108
- Kaiser Permanente-San Diego Mission
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San Francisco, California, Förenta staterna, 94115
- Kaiser Permanente-San Francisco
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San Francisco, California, Förenta staterna, 94115
- California Pacific Medical Center-Pacific Campus
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San Jose, California, Förenta staterna, 95119
- Kaiser Permanente-Santa Teresa-San Jose
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San Leandro, California, Förenta staterna, 94577
- Kaiser Permanente San Leandro
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San Marcos, California, Förenta staterna, 92078
- Kaiser Permanente-San Marcos
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San Pablo, California, Förenta staterna, 94806
- Doctors Medical Center- JC Robinson Regional Cancer Center
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San Rafael, California, Förenta staterna, 94903
- Kaiser Permanente-San Rafael
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Santa Clara, California, Förenta staterna, 95051
- Kaiser Permanente Medical Center - Santa Clara
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Santa Cruz, California, Förenta staterna, 95065
- Palo Alto Medical Foundation-Santa Cruz
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Santa Rosa, California, Förenta staterna, 95403
- Kaiser Permanente-Santa Rosa
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Santa Rosa, California, Förenta staterna, 95403
- Sutter Pacific Medical Foundation
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South San Francisco, California, Förenta staterna, 94080
- Kaiser Permanente-South San Francisco
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Stockton, California, Förenta staterna, 95210
- Kaiser Permanente-Stockton
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Sunnyvale, California, Förenta staterna, 94086
- Palo Alto Medical Foundation-Sunnyvale
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Vacaville, California, Förenta staterna, 95688
- Kaiser Permanente Medical Center-Vacaville
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Vallejo, California, Förenta staterna, 94589
- Kaiser Permanente-Vallejo
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Vallejo, California, Förenta staterna, 94589
- Sutter Solano Medical Center/Cancer Center
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Walnut Creek, California, Förenta staterna, 94596
- Kaiser Permanente-Walnut Creek
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Woodland Hills, California, Förenta staterna, 91367
- Kaiser Permanente-Woodland Hills
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Colorado
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Aurora, Colorado, Förenta staterna, 80012
- Rocky Mountain Cancer Centers-Aurora
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Aurora, Colorado, Förenta staterna, 80012
- The Medical Center of Aurora
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Aurora, Colorado, Förenta staterna, 80045
- UCHealth University of Colorado Hospital
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Boulder, Colorado, Förenta staterna, 80303
- Boulder Community Foothills Hospital
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Boulder, Colorado, Förenta staterna, 80304
- Rocky Mountain Cancer Centers-Boulder
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Colorado Springs, Colorado, Förenta staterna, 80907
- Penrose-Saint Francis Healthcare
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Colorado Springs, Colorado, Förenta staterna, 80909
- UCHealth Memorial Hospital Central
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Colorado Springs, Colorado, Förenta staterna, 80907
- Rocky Mountain Cancer Centers-Penrose
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Denver, Colorado, Förenta staterna, 80218
- Presbyterian - Saint Lukes Medical Center - Health One
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Denver, Colorado, Förenta staterna, 80220
- Rose Medical Center
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Denver, Colorado, Förenta staterna, 80218
- Rocky Mountain Cancer Centers-Midtown
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Denver, Colorado, Förenta staterna, 80220
- Rocky Mountain Cancer Centers-Rose
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Denver, Colorado, Förenta staterna, 80218
- Colorado Blood Cancer Institute
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Denver, Colorado, Förenta staterna, 80222
- Western States Cancer Research NCORP
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Denver, Colorado, Förenta staterna, 80218
- Saint Joseph Hospital - Cancer Centers of Colorado
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Denver, Colorado, Förenta staterna, 80210
- AdventHealth Porter
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Durango, Colorado, Förenta staterna, 81301
- Mercy Medical Center
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Durango, Colorado, Förenta staterna, 81301
- Southwest Oncology PC
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Englewood, Colorado, Förenta staterna, 80113
- Mountain Blue Cancer Care Center - Swedish
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Englewood, Colorado, Förenta staterna, 80113
- Swedish Medical Center
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Fort Collins, Colorado, Förenta staterna, 80524
- Poudre Valley Hospital
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Golden, Colorado, Förenta staterna, 80401
- Mountain Blue Cancer Care Center
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Greeley, Colorado, Förenta staterna, 80631
- Banner North Colorado Medical Center
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Greenwood Village, Colorado, Förenta staterna, 80111
- Rocky Mountain Cancer Centers-Greenwood Village
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Lakewood, Colorado, Förenta staterna, 80228
- Saint Anthony Hospital
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Lakewood, Colorado, Förenta staterna, 80228
- Rocky Mountain Cancer Centers-Lakewood
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Littleton, Colorado, Förenta staterna, 80120
- Rocky Mountain Cancer Centers-Littleton
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Littleton, Colorado, Förenta staterna, 80122
- AdventHealth Littleton
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Lone Tree, Colorado, Förenta staterna, 80124
- Sky Ridge Medical Center
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Lone Tree, Colorado, Förenta staterna, 80124
- Rocky Mountain Cancer Centers-Sky Ridge
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Longmont, Colorado, Förenta staterna, 80501
- Longmont United Hospital
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Longmont, Colorado, Förenta staterna, 80501
- Rocky Mountain Cancer Centers-Longmont
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Loveland, Colorado, Förenta staterna, 80539
- Banner McKee Medical Center
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Parker, Colorado, Förenta staterna, 80138
- Rocky Mountain Cancer Centers-Parker
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Parker, Colorado, Förenta staterna, 80138
- AdventHealth Parker
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Pueblo, Colorado, Förenta staterna, 81004
- Saint Mary Corwin Medical Center
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Pueblo, Colorado, Förenta staterna, 81008
- Rocky Mountain Cancer Centers - Pueblo
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Thornton, Colorado, Förenta staterna, 80260
- Rocky Mountain Cancer Centers-Thornton
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Wheat Ridge, Colorado, Förenta staterna, 80401
- Intermountain Health Lutheran Hospital
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Connecticut
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Hartford, Connecticut, Förenta staterna, 06105
- Smilow Cancer Hospital Care Center at Saint Francis
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Hartford, Connecticut, Förenta staterna, 06102
- Hartford Hospital
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Delaware
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Lewes, Delaware, Förenta staterna, 19958
- Beebe Medical Center
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Newark, Delaware, Förenta staterna, 19713
- Helen F Graham Cancer Center
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Newark, Delaware, Förenta staterna, 19713
- Delaware Clinical and Laboratory Physicians PA
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Newark, Delaware, Förenta staterna, 19713
- Medical Oncology Hematology Consultants PA
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Newark, Delaware, Förenta staterna, 19718
- Christiana Care Health System-Christiana Hospital
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Rehoboth Beach, Delaware, Förenta staterna, 19971
- Beebe Health Campus
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Seaford, Delaware, Förenta staterna, 19973
- TidalHealth Nanticoke / Allen Cancer Center
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Wilmington, Delaware, Förenta staterna, 19801
- Christiana Care Health System-Wilmington Hospital
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District of Columbia
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Washington D.C., District of Columbia, Förenta staterna, 20010
- MedStar Washington Hospital Center
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Washington D.C., District of Columbia, Förenta staterna, 20007
- MedStar Georgetown University Hospital
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Florida
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Deerfield Beach, Florida, Förenta staterna, 33442
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach
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Gainesville, Florida, Förenta staterna, 32610
- University of Florida Health Science Center - Gainesville
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Miami, Florida, Förenta staterna, 33136
- University of Miami Miller School of Medicine-Sylvester Cancer Center
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Orlando, Florida, Förenta staterna, 32806
- Orlando Health Cancer Institute
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Orlando, Florida, Förenta staterna, 32803
- AdventHealth Orlando
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Georgia
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Athens, Georgia, Förenta staterna, 30607
- University Cancer and Blood Center LLC
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Atlanta, Georgia, Förenta staterna, 30342
- Northside Hospital
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Augusta, Georgia, Förenta staterna, 30912
- Augusta University Medical Center
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Cumming, Georgia, Förenta staterna, 30041
- Northside Hospital-Forsyth
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Decatur, Georgia, Förenta staterna, 30033
- Emory Decatur Hospital
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Gainesville, Georgia, Förenta staterna, 30501
- Northeast Georgia Medical Center-Gainesville
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Savannah, Georgia, Förenta staterna, 31405
- Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
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Savannah, Georgia, Förenta staterna, 31404
- Memorial Health University Medical Center
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Savannah, Georgia, Förenta staterna, 31404
- Summit Cancer Care-Memorial
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Savannah, Georgia, Förenta staterna, 31404
- Low Country Cancer Care
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Hawaii
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Honolulu, Hawaii, Förenta staterna, 96813
- Queen's Medical Center
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Honolulu, Hawaii, Förenta staterna, 96817
- The Cancer Center of Hawaii-Liliha
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Honolulu, Hawaii, Förenta staterna, 96813
- Hawaii Cancer Care Inc - Waterfront Plaza
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Honolulu, Hawaii, Förenta staterna, 96813
- Straub Clinic and Hospital
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Honolulu, Hawaii, Förenta staterna, 96813
- University of Hawaii Cancer Center
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Honolulu, Hawaii, Förenta staterna, 96817
- Hawaii Cancer Care Inc-Liliha
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Honolulu, Hawaii, Förenta staterna, 96817
- Kuakini Medical Center
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Honolulu, Hawaii, Förenta staterna, 96817
- Queen's Cancer Center - Kuakini
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Honolulu, Hawaii, Förenta staterna, 96819
- Kaiser Permanente Moanalua Medical Center
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Kailua, Hawaii, Förenta staterna, 96734
- Castle Medical Center
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Lihue, Hawaii, Förenta staterna, 96766
- Wilcox Memorial Hospital and Kauai Medical Clinic
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‘Aiea, Hawaii, Förenta staterna, 96701
- Pali Momi Medical Center
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‘Aiea, Hawaii, Förenta staterna, 96701
- Queen's Cancer Center - Pearlridge
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‘Aiea, Hawaii, Förenta staterna, 96701
- The Cancer Center of Hawaii-Pali Momi
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Idaho
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Boise, Idaho, Förenta staterna, 83706
- Saint Alphonsus Cancer Care Center-Boise
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Coeur d'Alene, Idaho, Förenta staterna, 83814
- Kootenai Health - Coeur d'Alene
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Lewiston, Idaho, Förenta staterna, 83501
- Saint Joseph Regional Medical Center
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Post Falls, Idaho, Förenta staterna, 83854
- Kootenai Clinic Cancer Services - Post Falls
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Sandpoint, Idaho, Förenta staterna, 83864
- Kootenai Clinic Cancer Services - Sandpoint
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Illinois
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Aurora, Illinois, Förenta staterna, 60504
- Rush-Copley Medical Center
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Bloomington, Illinois, Förenta staterna, 61704
- Illinois CancerCare-Bloomington
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Bloomington, Illinois, Förenta staterna, 61701
- OSF Saint Joseph Medical Center
-
Canton, Illinois, Förenta staterna, 61520
- Illinois CancerCare-Canton
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Carbondale, Illinois, Förenta staterna, 62902
- Memorial Hospital of Carbondale
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Carthage, Illinois, Förenta staterna, 62321
- Illinois CancerCare-Carthage
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Centralia, Illinois, Förenta staterna, 62801
- Centralia Oncology Clinic
-
Chicago, Illinois, Förenta staterna, 60612
- University of Illinois
-
Chicago, Illinois, Förenta staterna, 60612
- John H Stroger Jr Hospital of Cook County
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Chicago, Illinois, Förenta staterna, 60608
- Mount Sinai Hospital Medical Center
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Chicago, Illinois, Förenta staterna, 60625
- Swedish Covenant Hospital
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Chicago, Illinois, Förenta staterna, 60631
- Presence Resurrection Medical Center
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Danville, Illinois, Förenta staterna, 61832
- Carle at The Riverfront
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Decatur, Illinois, Förenta staterna, 62526
- Decatur Memorial Hospital
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Decatur, Illinois, Förenta staterna, 62526
- Cancer Care Specialists of Illinois - Decatur
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Effingham, Illinois, Förenta staterna, 62401
- Crossroads Cancer Center
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Effingham, Illinois, Förenta staterna, 62401
- Carle Physician Group-Effingham
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Elk Grove Village, Illinois, Förenta staterna, 60007
- Ascension Alexian Brothers - Elk Grove Village
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Eureka, Illinois, Förenta staterna, 61530
- Illinois CancerCare-Eureka
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Evanston, Illinois, Förenta staterna, 60202
- Saint Francis Hospital
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Galesburg, Illinois, Förenta staterna, 61401
- Western Illinois Cancer Treatment Center
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Galesburg, Illinois, Förenta staterna, 61401
- Illinois CancerCare-Galesburg
-
Geneva, Illinois, Förenta staterna, 60134
- Northwestern Medicine Cancer Center Delnor
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Harvey, Illinois, Förenta staterna, 60426
- Ingalls Memorial Hospital
-
Kankakee, Illinois, Förenta staterna, 60901
- Presence Saint Mary's Hospital
-
Kewanee, Illinois, Förenta staterna, 61443
- Illinois CancerCare-Kewanee Clinic
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Macomb, Illinois, Förenta staterna, 61455
- Illinois CancerCare-Macomb
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Mattoon, Illinois, Förenta staterna, 61938
- Carle Physician Group-Mattoon/Charleston
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Mount Vernon, Illinois, Förenta staterna, 62864
- SSM Health Good Samaritan
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Naperville, Illinois, Förenta staterna, 60540
- Edward Hospital/Cancer Center
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O'Fallon, Illinois, Förenta staterna, 62269
- Cancer Care Center of O'Fallon
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Ottawa, Illinois, Förenta staterna, 61350
- Illinois CancerCare-Ottawa Clinic
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Ottawa, Illinois, Förenta staterna, 61350
- Radiation Oncology of Northern Illinois
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Pekin, Illinois, Förenta staterna, 61554
- Illinois CancerCare-Pekin
-
Pekin, Illinois, Förenta staterna, 61554
- OSF Saint Francis Radiation Oncology at Pekin
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Peoria, Illinois, Förenta staterna, 61636
- Methodist Medical Center of Illinois
-
Peoria, Illinois, Förenta staterna, 61637
- OSF Saint Francis Medical Center
-
Peoria, Illinois, Förenta staterna, 61615
- Illinois CancerCare-Peoria
-
Peoria, Illinois, Förenta staterna, 61615
- OSF Saint Francis Radiation Oncology at Peoria Cancer Center
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Peru, Illinois, Förenta staterna, 61354
- Illinois CancerCare-Peru
-
Peru, Illinois, Förenta staterna, 61354
- Valley Radiation Oncology
-
Plainfield, Illinois, Förenta staterna, 60585
- Edward Hospital/Cancer Center?Plainfield
-
Princeton, Illinois, Förenta staterna, 61356
- Illinois CancerCare-Princeton
-
Rockford, Illinois, Förenta staterna, 61108
- OSF Saint Anthony Medical Center
-
Rockford, Illinois, Förenta staterna, 61114
- UW Health Carbone Cancer Center Rockford
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Springfield, Illinois, Förenta staterna, 62702
- Southern Illinois University School of Medicine
-
Springfield, Illinois, Förenta staterna, 62702
- Springfield Clinic
-
Springfield, Illinois, Förenta staterna, 62702
- Central Illinois Hematology Oncology Center
-
Springfield, Illinois, Förenta staterna, 62781
- Springfield Memorial Hospital
-
Urbana, Illinois, Förenta staterna, 61801
- Carle Cancer Center
-
Urbana, Illinois, Förenta staterna, 61801
- The Carle Foundation Hospital
-
Warrenville, Illinois, Förenta staterna, 60555
- Northwestern Medicine Cancer Center Warrenville
-
Yorkville, Illinois, Förenta staterna, 60560
- Rush-Copley Healthcare Center
-
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Indiana
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Crown Point, Indiana, Förenta staterna, 46307
- Michiana Hematology Oncology PC-Crown Point
-
Elkhart, Indiana, Förenta staterna, 46515
- Elkhart General Hospital
-
Elkhart, Indiana, Förenta staterna, 46514
- Michiana Hematology Oncology PC-Elkhart
-
Elkhart, Indiana, Förenta staterna, 46514-2098
- Elkhart Clinic
-
Indianapolis, Indiana, Förenta staterna, 46237
- Franciscan Health Indianapolis
-
Kokomo, Indiana, Förenta staterna, 46904
- Community Howard Regional Health
-
La Porte, Indiana, Förenta staterna, 46350
- IU Health La Porte Hospital
-
Michigan City, Indiana, Förenta staterna, 46360
- Franciscan Saint Anthony Health-Michigan City
-
Michigan City, Indiana, Förenta staterna, 46360
- Woodland Cancer Care Center
-
Mishawaka, Indiana, Förenta staterna, 46545
- Michiana Hematology Oncology PC-Mishawaka
-
Mishawaka, Indiana, Förenta staterna, 46545
- Saint Joseph Regional Medical Center-Mishawaka
-
Munster, Indiana, Förenta staterna, 46321
- The Community Hospital
-
Plymouth, Indiana, Förenta staterna, 46563
- Michiana Hematology Oncology PC-Plymouth
-
Richmond, Indiana, Förenta staterna, 47374
- Reid Health
-
South Bend, Indiana, Förenta staterna, 46628
- Northern Indiana Cancer Research Consortium
-
Terre Haute, Indiana, Förenta staterna, 47804
- Union Hospital
-
Westville, Indiana, Förenta staterna, 46391
- Michiana Hematology Oncology PC-Westville
-
-
Iowa
-
Ames, Iowa, Förenta staterna, 50010
- Mary Greeley Medical Center
-
Ames, Iowa, Förenta staterna, 50010
- McFarland Clinic - Ames
-
Boone, Iowa, Förenta staterna, 50036
- McFarland Clinic - Boone
-
Cedar Rapids, Iowa, Förenta staterna, 52403
- Mercy Hospital
-
Cedar Rapids, Iowa, Förenta staterna, 52403
- Oncology Associates at Mercy Medical Center
-
Clive, Iowa, Förenta staterna, 50325
- Mercy Cancer Center-West Lakes
-
Clive, Iowa, Förenta staterna, 50325
- UI Health Care Mission Cancer and Blood - West Des Moines Clinic
-
Council Bluffs, Iowa, Förenta staterna, 51503
- Alegent Health Mercy Hospital
-
Creston, Iowa, Förenta staterna, 50801
- Greater Regional Medical Center
-
Des Moines, Iowa, Förenta staterna, 50314
- Mercy Medical Center - Des Moines
-
Des Moines, Iowa, Förenta staterna, 50314
- UI Health Care Mission Cancer and Blood - Laurel Clinic
-
Fort Dodge, Iowa, Förenta staterna, 50501
- McFarland Clinic - Trinity Cancer Center
-
Iowa City, Iowa, Förenta staterna, 52242
- University of Iowa/Holden Comprehensive Cancer Center
-
Jefferson, Iowa, Förenta staterna, 50129
- McFarland Clinic - Jefferson
-
Marshalltown, Iowa, Förenta staterna, 50158
- McFarland Clinic - Marshalltown
-
West Des Moines, Iowa, Förenta staterna, 50266
- Mercy Medical Center-West Lakes
-
-
Kansas
-
Chanute, Kansas, Förenta staterna, 66720
- Cancer Center of Kansas - Chanute
-
Dodge City, Kansas, Förenta staterna, 67801
- Cancer Center of Kansas - Dodge City
-
El Dorado, Kansas, Förenta staterna, 67042
- Cancer Center of Kansas - El Dorado
-
Fort Scott, Kansas, Förenta staterna, 66701
- Cancer Center of Kansas - Fort Scott
-
Independence, Kansas, Förenta staterna, 67301
- Cancer Center of Kansas-Independence
-
Kingman, Kansas, Förenta staterna, 67068
- Cancer Center of Kansas-Kingman
-
Lawrence, Kansas, Förenta staterna, 66044
- Lawrence Memorial Hospital
-
Liberal, Kansas, Förenta staterna, 67905
- Cancer Center of Kansas-Liberal
-
Manhattan, Kansas, Förenta staterna, 66502
- Cancer Center of Kansas-Manhattan
-
McPherson, Kansas, Förenta staterna, 67460
- Cancer Center of Kansas - McPherson
-
Newton, Kansas, Förenta staterna, 67114
- Cancer Center of Kansas - Newton
-
Parsons, Kansas, Förenta staterna, 67357
- Cancer Center of Kansas - Parsons
-
Pratt, Kansas, Förenta staterna, 67124
- Cancer Center of Kansas - Pratt
-
Salina, Kansas, Förenta staterna, 67401
- Cancer Center of Kansas - Salina
-
Topeka, Kansas, Förenta staterna, 66606
- Cotton O'Neil Cancer Center / Stormont Vail Health
-
Wellington, Kansas, Förenta staterna, 67152
- Cancer Center of Kansas - Wellington
-
Wichita, Kansas, Förenta staterna, 67214
- Ascension Via Christi Hospitals Wichita
-
Wichita, Kansas, Förenta staterna, 67208
- Cancer Center of Kansas-Wichita Medical Arts Tower
-
Wichita, Kansas, Förenta staterna, 67214
- Cancer Center of Kansas - Wichita
-
Wichita, Kansas, Förenta staterna, 67208
- Associates In Womens Health
-
Wichita, Kansas, Förenta staterna, 67214
- Wichita NCI Community Oncology Research Program
-
Winfield, Kansas, Förenta staterna, 67156
- Cancer Center of Kansas - Winfield
-
-
Kentucky
-
Bardstown, Kentucky, Förenta staterna, 40004
- Flaget Memorial Hospital
-
Corbin, Kentucky, Förenta staterna, 40701
- Baptist Health Corbin
-
Corbin, Kentucky, Förenta staterna, 40701
- Commonwealth Cancer Center-Corbin
-
Crestview Hills, Kentucky, Förenta staterna, 41017
- Oncology Hematology Care Inc-Crestview
-
Elizabethtown, Kentucky, Förenta staterna, 42701
- Baptist Health Hardin
-
Lexington, Kentucky, Förenta staterna, 40536
- University of Kentucky/Markey Cancer Center
-
Lexington, Kentucky, Förenta staterna, 40504
- Saint Joseph Radiation Oncology Resource Center
-
Lexington, Kentucky, Förenta staterna, 40509
- Saint Joseph Hospital East
-
Lexington, Kentucky, Förenta staterna, 40503
- Baptist Health Lexington
-
Louisville, Kentucky, Förenta staterna, 40202
- The James Graham Brown Cancer Center at University of Louisville
-
Louisville, Kentucky, Förenta staterna, 40202
- Jewish Hospital
-
Louisville, Kentucky, Förenta staterna, 40245
- UofL Health Medical Center Northeast
-
Louisville, Kentucky, Förenta staterna, 40207
- Baptist Health Louisville
-
Louisville, Kentucky, Förenta staterna, 40215
- Saints Mary and Elizabeth Hospital
-
Madisonville, Kentucky, Förenta staterna, 42431
- Baptist Health Madisonville/Merle Mahr Cancer Center
-
Paducah, Kentucky, Förenta staterna, 42003
- Baptist Health Paducah
-
Shepherdsville, Kentucky, Förenta staterna, 40165
- Jewish Hospital Medical Center South
-
-
Louisiana
-
Baton Rouge, Louisiana, Förenta staterna, 70809
- Ochsner Health Center-Summa
-
Kenner, Louisiana, Förenta staterna, 70065
- Ochsner Medical Center Kenner
-
New Orleans, Louisiana, Förenta staterna, 70121
- Ochsner Medical Center Jefferson
-
-
Maine
-
Bangor, Maine, Förenta staterna, 04401
- Eastern Maine Medical Center
-
Brewer, Maine, Förenta staterna, 04412
- Lafayette Family Cancer Center-EMMC
-
-
Maryland
-
Baltimore, Maryland, Förenta staterna, 21237
- MedStar Franklin Square Medical Center/Weinberg Cancer Institute
-
Baltimore, Maryland, Förenta staterna, 21204
- Greater Baltimore Medical Center
-
Elkton, Maryland, Förenta staterna, 21921
- Christiana Care - Union Hospital
-
Frederick, Maryland, Förenta staterna, 21701
- Frederick Memorial Hospital
-
-
Massachusetts
-
Fall River, Massachusetts, Förenta staterna, 02721
- Saint Anne's Hospital
-
Pittsfield, Massachusetts, Förenta staterna, 01201
- Berkshire Medical Center - Cancer Center
-
-
Michigan
-
Adrian, Michigan, Förenta staterna, 49221
- Bixby Medical Center
-
Adrian, Michigan, Förenta staterna, 49221
- Hickman Cancer Center
-
Ann Arbor, Michigan, Förenta staterna, 48106
- Michigan Cancer Research Consortium NCORP
-
Ann Arbor, Michigan, Förenta staterna, 48106
- Trinity Health Saint Joseph Mercy Hospital Ann Arbor
-
Ann Arbor, Michigan, Förenta staterna, 48109
- University of Michigan Comprehensive Cancer Center
-
Dearborn, Michigan, Förenta staterna, 48124
- Corewell Health Dearborn Hospital
-
Detroit, Michigan, Förenta staterna, 48202
- Henry Ford Hospital
-
Detroit, Michigan, Förenta staterna, 48201
- Wayne State University/Karmanos Cancer Institute
-
Detroit, Michigan, Förenta staterna, 48236
- Henry Ford Health Saint John Hospital
-
Farmington Hills, Michigan, Förenta staterna, 48334
- Weisberg Cancer Treatment Center
-
Farmington Hills, Michigan, Förenta staterna, 48336
- Corewell Health Farmington Hills Hospital
-
Flint, Michigan, Förenta staterna, 48503
- Hurley Medical Center
-
Flint, Michigan, Förenta staterna, 48503
- Genesys Hurley Cancer Institute
-
Grosse Pointe, Michigan, Förenta staterna, 48230
- William Beaumont Hospital-Grosse Pointe
-
Jackson, Michigan, Förenta staterna, 49201
- Allegiance Health
-
Kalamazoo, Michigan, Förenta staterna, 49007
- West Michigan Cancer Center
-
Lansing, Michigan, Förenta staterna, 48912
- University of Michigan Health - Sparrow Lansing
-
Livonia, Michigan, Förenta staterna, 48154
- Trinity Health Saint Mary Mercy Livonia Hospital
-
Midland, Michigan, Förenta staterna, 48670
- MyMichigan Medical Center Midland
-
Monroe, Michigan, Förenta staterna, 48162
- Mercy Memorial Hospital
-
Monroe, Michigan, Förenta staterna, 48162
- Toledo Clinic Cancer Centers-Monroe
-
Pontiac, Michigan, Förenta staterna, 48341
- Trinity Health Saint Joseph Mercy Oakland Hospital
-
Port Huron, Michigan, Förenta staterna, 48060
- Lake Huron Medical Center
-
Roseville, Michigan, Förenta staterna, 48066
- Michigan Cancer Specialists
-
Royal Oak, Michigan, Förenta staterna, 48073
- Cancer Care Associates PC
-
Royal Oak, Michigan, Förenta staterna, 48073
- Comprehensive Medical Center PLLC
-
Royal Oak, Michigan, Förenta staterna, 48073
- Oakland Medical Group
-
Royal Oak, Michigan, Förenta staterna, 48067
- Oakland Colon Rectal Associates
-
Royal Oak, Michigan, Förenta staterna, 48073
- Hematology Oncology Consultants PC-Royal Oak
-
Royal Oak, Michigan, Förenta staterna, 48073
- Corewell Health William Beaumont University Hospital
-
Saginaw, Michigan, Förenta staterna, 48601
- MyMichigan Medical Center Saginaw
-
Sterling Heights, Michigan, Förenta staterna, 48312
- Premier Hematology Oncology Care
-
Sterling Heights, Michigan, Förenta staterna, 48314
- Mitchell Folbe MD PC
-
Troy, Michigan, Förenta staterna, 48084
- Michigan Institute of Urology-Town Center
-
Troy, Michigan, Förenta staterna, 48085
- Claudia BR Herke MD PC
-
Troy, Michigan, Förenta staterna, 48098
- Hematology Oncology Consultants PC-Troy
-
Troy, Michigan, Förenta staterna, 48085
- Corewell Health Beaumont Troy Hospital
-
Warren, Michigan, Förenta staterna, 48093
- Henry Ford Health Warren Hospital
-
-
Minnesota
-
Bemidji, Minnesota, Förenta staterna, 56601
- Sanford Joe Lueken Cancer Center
-
Brainerd, Minnesota, Förenta staterna, 56401
- Essentia Health Saint Joseph's Medical Center
-
Burnsville, Minnesota, Förenta staterna, 55337
- Fairview Ridges Hospital
-
Coon Rapids, Minnesota, Förenta staterna, 55433
- Mercy Hospital
-
Duluth, Minnesota, Förenta staterna, 55805
- Essentia Health Cancer Center
-
Duluth, Minnesota, Förenta staterna, 55805
- Essentia Health Saint Mary's Medical Center
-
Duluth, Minnesota, Förenta staterna, 55805
- Miller-Dwan Hospital
-
Edina, Minnesota, Förenta staterna, 55435
- Fairview Southdale Hospital
-
Fergus Falls, Minnesota, Förenta staterna, 56537
- Lake Region Healthcare Corporation-Cancer Care
-
Fridley, Minnesota, Förenta staterna, 55432
- Unity Hospital
-
Hutchinson, Minnesota, Förenta staterna, 55350
- Hutchinson Area Health Care
-
Maplewood, Minnesota, Förenta staterna, 55109
- Saint John's Hospital - Healtheast
-
Maplewood, Minnesota, Förenta staterna, 55109
- Minnesota Oncology Hematology PA-Maplewood
-
Minneapolis, Minnesota, Förenta staterna, 55415
- Hennepin County Medical Center
-
Minneapolis, Minnesota, Förenta staterna, 55407
- Abbott-Northwestern Hospital
-
Minneapolis, Minnesota, Förenta staterna, 55454
- Health Partners Inc
-
New Ulm, Minnesota, Förenta staterna, 56073
- New Ulm Medical Center
-
Robbinsdale, Minnesota, Förenta staterna, 55422
- North Memorial Medical Health Center
-
Saint Louis Park, Minnesota, Förenta staterna, 55416
- Park Nicollet Clinic - Saint Louis Park
-
Saint Louis Park, Minnesota, Förenta staterna, 55416
- Metro Minnesota Community Oncology Research Consortium
-
Saint Paul, Minnesota, Förenta staterna, 55101
- Regions Hospital
-
Saint Paul, Minnesota, Förenta staterna, 55102
- United Hospital
-
Shakopee, Minnesota, Förenta staterna, 55379
- Saint Francis Regional Medical Center
-
Stillwater, Minnesota, Förenta staterna, 55082
- Lakeview Hospital
-
Waconia, Minnesota, Förenta staterna, 55387
- Ridgeview Medical Center
-
Willmar, Minnesota, Förenta staterna, 56201
- Rice Memorial Hospital
-
Woodbury, Minnesota, Förenta staterna, 55125
- Minnesota Oncology Hematology PA-Woodbury
-
-
Missouri
-
Ballwin, Missouri, Förenta staterna, 63011
- Mercy Oncology and Hematology - Clayton-Clarkson
-
Bolivar, Missouri, Förenta staterna, 65613
- Central Care Cancer Center - Bolivar
-
Bonne Terre, Missouri, Förenta staterna, 63628
- Parkland Health Center-Bonne Terre
-
Branson, Missouri, Förenta staterna, 65616
- Cox Cancer Center Branson
-
Cape Girardeau, Missouri, Förenta staterna, 63703
- Saint Francis Medical Center
-
Cape Girardeau, Missouri, Förenta staterna, 63703
- Mercy Cancer Center - Cape Girardeau
-
Columbia, Missouri, Förenta staterna, 65212
- MU Health - University Hospital/Ellis Fischel Cancer Center
-
Jefferson City, Missouri, Förenta staterna, 65109
- MU Health Care Goldschmidt Cancer Center
-
Joplin, Missouri, Förenta staterna, 64804
- Freeman Health System
-
Joplin, Missouri, Förenta staterna, 64804
- Mercy Hospital Joplin
-
Rolla, Missouri, Förenta staterna, 65401
- Mercy Clinic-Rolla-Cancer and Hematology
-
Rolla, Missouri, Förenta staterna, 65401
- Phelps Health Delbert Day Cancer Institute
-
Sainte Genevieve, Missouri, Förenta staterna, 63670
- Sainte Genevieve County Memorial Hospital
-
Springfield, Missouri, Förenta staterna, 65807
- CoxHealth South Hospital
-
Springfield, Missouri, Förenta staterna, 65804
- Mercy Hospital Springfield
-
St Louis, Missouri, Förenta staterna, 63131
- Missouri Baptist Medical Center
-
St Louis, Missouri, Förenta staterna, 63109
- Mercy Infusion Center - Chippewa
-
St Louis, Missouri, Förenta staterna, 63141
- Mercy Hospital Saint Louis
-
Sullivan, Missouri, Förenta staterna, 63080
- Missouri Baptist Sullivan Hospital
-
Sunset Hills, Missouri, Förenta staterna, 63127
- BJC Outpatient Center at Sunset Hills
-
-
Montana
-
Anaconda, Montana, Förenta staterna, 59711
- Community Hospital of Anaconda
-
Billings, Montana, Förenta staterna, 59101
- Billings Clinic Cancer Center
-
Billings, Montana, Förenta staterna, 59101
- Saint Vincent Healthcare
-
Billings, Montana, Förenta staterna, 59102
- Montana Cancer Consortium NCORP
-
Bozeman, Montana, Förenta staterna, 59715
- Bozeman Health Deaconess Hospital
-
Butte, Montana, Förenta staterna, 59701
- Saint James Community Hospital and Cancer Treatment Center
-
Great Falls, Montana, Förenta staterna, 59405
- Benefis Sletten Cancer Institute
-
Helena, Montana, Förenta staterna, 59601
- Saint Peter's Community Hospital
-
Kalispell, Montana, Förenta staterna, 59901
- Logan Health Medical Center
-
Missoula, Montana, Förenta staterna, 59802
- Saint Patrick Hospital - Community Hospital
-
Missoula, Montana, Förenta staterna, 59804
- Community Medical Center
-
-
Nebraska
-
Grand Island, Nebraska, Förenta staterna, 68803
- Nebraska Cancer Specialists/Oncology Hematology West PC
-
Kearney, Nebraska, Förenta staterna, 68847
- CHI Health Good Samaritan
-
Kearney, Nebraska, Förenta staterna, 68845
- Fred and Pamela Buffett Cancer Center - Kearney
-
Lincoln, Nebraska, Förenta staterna, 68510
- Saint Elizabeth Regional Medical Center
-
Omaha, Nebraska, Förenta staterna, 68124
- Alegent Health Bergan Mercy Medical Center
-
Omaha, Nebraska, Förenta staterna, 68122
- Alegent Health Immanuel Medical Center
-
Omaha, Nebraska, Förenta staterna, 68130
- Alegent Health Lakeside Hospital
-
Omaha, Nebraska, Förenta staterna, 68131
- Creighton University Medical Center
-
Omaha, Nebraska, Förenta staterna, 68122
- Hematology and Oncology Consultants PC
-
Papillion, Nebraska, Förenta staterna, 68046
- Midlands Community Hospital
-
-
Nevada
-
Henderson, Nevada, Förenta staterna, 89052
- Comprehensive Cancer Centers of Nevada - Henderson
-
Henderson, Nevada, Förenta staterna, 89052
- Cancer and Blood Specialists-Henderson
-
Henderson, Nevada, Förenta staterna, 89052
- Las Vegas Cancer Center-Henderson
-
Henderson, Nevada, Förenta staterna, 89074
- Comprehensive Cancer Centers of Nevada-Southeast Henderson
-
Henderson, Nevada, Förenta staterna, 89074
- GenesisCare USA - Henderson
-
Las Vegas, Nevada, Förenta staterna, 89144
- Summerlin Hospital Medical Center
-
Las Vegas, Nevada, Förenta staterna, 89106
- Radiation Oncology Centers of Nevada Central
-
Las Vegas, Nevada, Förenta staterna, 89109
- GenesisCare USA - Las Vegas
-
Las Vegas, Nevada, Förenta staterna, 89119
- Radiation Oncology Centers of Nevada Southeast
-
Las Vegas, Nevada, Förenta staterna, 89128
- Comprehensive Cancer Centers of Nevada - Northwest
-
Las Vegas, Nevada, Förenta staterna, 89135
- Alliance for Childhood Diseases/Cure 4 the Kids Foundation
-
Las Vegas, Nevada, Förenta staterna, 89144
- Comprehensive Cancer Centers of Nevada-Summerlin
-
Las Vegas, Nevada, Förenta staterna, 89148
- Comprehensive Cancer Centers of Nevada
-
Las Vegas, Nevada, Förenta staterna, 89148
- OptumCare Cancer Care at Fort Apache
-
Las Vegas, Nevada, Förenta staterna, 89169
- Comprehensive Cancer Centers of Nevada - Central Valley
-
Las Vegas, Nevada, Förenta staterna, 89106
- Cancer and Blood Specialists-Shadow
-
Las Vegas, Nevada, Förenta staterna, 89109
- HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
-
Las Vegas, Nevada, Förenta staterna, 89113
- HealthCare Partners Medical Group Oncology/Hematology-San Martin
-
Las Vegas, Nevada, Förenta staterna, 89121
- Cancer Therapy and Integrative Medicine
-
Las Vegas, Nevada, Förenta staterna, 89128
- Cancer and Blood Specialists-Tenaya
-
Las Vegas, Nevada, Förenta staterna, 89128
- GenesisCare USA - Vegas Tenaya
-
Las Vegas, Nevada, Förenta staterna, 89128
- HealthCare Partners Medical Group Oncology/Hematology-Tenaya
-
Las Vegas, Nevada, Förenta staterna, 89148-2405
- Las Vegas Cancer Center-Medical Center
-
Las Vegas, Nevada, Förenta staterna, 89148
- GenesisCare USA - Fort Apache
-
Las Vegas, Nevada, Förenta staterna, 89149
- HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
-
Las Vegas, Nevada, Förenta staterna, 89120
- Nevada Cancer Research Foundation NCORP
-
Reno, Nevada, Förenta staterna, 89502
- Renown Regional Medical Center
-
Reno, Nevada, Förenta staterna, 89503
- Saint Mary's Regional Medical Center
-
-
New Hampshire
-
Lebanon, New Hampshire, Förenta staterna, 03756
- Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
-
-
New Jersey
-
Elizabeth, New Jersey, Förenta staterna, 07207
- Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus
-
Englewood, New Jersey, Förenta staterna, 07631
- Englewood Hospital and Medical Center
-
Flemington, New Jersey, Förenta staterna, 08822
- Hunterdon Medical Center
-
Mullica Hill, New Jersey, Förenta staterna, 08062
- Inspira Medical Center Mullica Hill
-
Newark, New Jersey, Förenta staterna, 07112
- Newark Beth Israel Medical Center
-
Newton, New Jersey, Förenta staterna, 07860
- Newton Medical Center
-
Pompton, New Jersey, Förenta staterna, 07444
- Chilton Medical Center
-
Summit, New Jersey, Förenta staterna, 07902
- Overlook Hospital
-
Vineland, New Jersey, Förenta staterna, 08360
- Inspira Medical Center Vineland
-
-
New Mexico
-
Albuquerque, New Mexico, Förenta staterna, 87106
- University of New Mexico Cancer Center
-
Albuquerque, New Mexico, Förenta staterna, 87106
- Hematology Oncology Associates
-
Las Cruces, New Mexico, Förenta staterna, 88011
- Memorial Medical Center-Las Cruces
-
Santa Fe, New Mexico, Förenta staterna, 87505
- Christus Saint Vincent Regional Cancer Center
-
-
New York
-
Buffalo, New York, Förenta staterna, 14263
- Roswell Park Cancer Institute
-
Glens Falls, New York, Förenta staterna, 12801
- Glens Falls Hospital
-
Middletown, New York, Förenta staterna, 10940
- Garnet Health Medical Center
-
New York, New York, Förenta staterna, 10032
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
-
-
North Carolina
-
Asheboro, North Carolina, Förenta staterna, 27203
- Randolph Hospital
-
Asheville, North Carolina, Förenta staterna, 28803
- AdventHealth Infusion Center Asheville
-
Burlington, North Carolina, Förenta staterna, 27215
- Cone Health Cancer Center at Alamance Regional
-
Chapel Hill, North Carolina, Förenta staterna, 27599
- UNC Lineberger Comprehensive Cancer Center
-
Clinton, North Carolina, Förenta staterna, 28328
- Southeastern Medical Oncology Center-Clinton
-
Goldsboro, North Carolina, Förenta staterna, 27534
- Southeastern Medical Oncology Center-Goldsboro
-
Goldsboro, North Carolina, Förenta staterna, 27534
- Wayne Memorial Hospital
-
Greensboro, North Carolina, Förenta staterna, 27403
- Cone Health Cancer Center
-
Hendersonville, North Carolina, Förenta staterna, 28792
- AdventHealth Hendersonville
-
Jacksonville, North Carolina, Förenta staterna, 28546
- Southeastern Medical Oncology Center-Jacksonville
-
Kernersville, North Carolina, Förenta staterna, 27284
- Novant Health Cancer Institute - Kernersville
-
Kinston, North Carolina, Förenta staterna, 28501
- ECU Health Oncology Kinston
-
Mebane, North Carolina, Förenta staterna, 27302
- Cone Heath Cancer Center at Mebane
-
Mount Airy, North Carolina, Förenta staterna, 27030
- Novant Health Cancer Institute - Mount Airy
-
North Wilkesboro, North Carolina, Förenta staterna, 28659
- Novant Health Cancer Institute - Wilkesboro
-
Pinehurst, North Carolina, Förenta staterna, 28374
- FirstHealth of the Carolinas-Moore Regional Hospital
-
Reidsville, North Carolina, Förenta staterna, 27320
- Annie Penn Memorial Hospital
-
Salisbury, North Carolina, Förenta staterna, 28144
- Novant Health Cancer Institute - Rowan
-
Statesville, North Carolina, Förenta staterna, 28677
- Iredell Memorial Hospital
-
Stateville, North Carolina, Förenta staterna, 28625
- Novant Health Cancer Institute - Statesville
-
Thomasville, North Carolina, Förenta staterna, 27360
- Novant Health Cancer Institute - Thomasville
-
Winston-Salem, North Carolina, Förenta staterna, 27157
- Wake Forest University Health Sciences
-
Winston-Salem, North Carolina, Förenta staterna, 27103
- Novant Health Forsyth Medical Center
-
Winston-Salem, North Carolina, Förenta staterna, 27103
- Novant Health Oncology Specialists
-
Winston-Salem, North Carolina, Förenta staterna, 27103
- Winston-Salem Health Care
-
Winston-Salem, North Carolina, Förenta staterna, 27104
- Southeast Clinical Oncology Research Consortium NCORP
-
-
North Dakota
-
Bismarck, North Dakota, Förenta staterna, 58501
- Sanford Bismarck Medical Center
-
Fargo, North Dakota, Förenta staterna, 58122
- Sanford Roger Maris Cancer Center
-
Fargo, North Dakota, Förenta staterna, 58103
- Essentia Health Cancer Center-South University Clinic
-
Fargo, North Dakota, Förenta staterna, 58122
- Sanford Broadway Medical Center
-
Grand Forks, North Dakota, Förenta staterna, 58201
- Altru Cancer Center
-
Minot, North Dakota, Förenta staterna, 58701
- Trinity Cancer Care Center
-
-
Ohio
-
Akron, Ohio, Förenta staterna, 44307
- Cleveland Clinic Akron General
-
Akron, Ohio, Förenta staterna, 44304
- Summa Health System - Akron Campus
-
Barberton, Ohio, Förenta staterna, 44203
- Summa Health System - Barberton Campus
-
Belpre, Ohio, Förenta staterna, 45714
- Strecker Cancer Center-Belpre
-
Bowling Green, Ohio, Förenta staterna, 43402
- Toledo Clinic Cancer Centers-Bowling Green
-
Canton, Ohio, Förenta staterna, 44710
- Aultman Health Foundation
-
Centerville, Ohio, Förenta staterna, 45459
- Miami Valley Hospital South
-
Centerville, Ohio, Förenta staterna, 45459
- Dayton Physicians LLC-Miami Valley South
-
Chillicothe, Ohio, Förenta staterna, 45601
- Adena Regional Medical Center
-
Cincinnati, Ohio, Förenta staterna, 45219
- The Christ Hospital
-
Cincinnati, Ohio, Förenta staterna, 45219
- University of Cincinnati Cancer Center-UC Medical Center
-
Cincinnati, Ohio, Förenta staterna, 45220
- Good Samaritan Hospital - Cincinnati
-
Cincinnati, Ohio, Förenta staterna, 45242
- Bethesda North Hospital
-
Cincinnati, Ohio, Förenta staterna, 45242
- Oncology Hematology Care Inc-Blue Ash
-
Cincinnati, Ohio, Förenta staterna, 45202
- Oncology Hematology Care Inc-Eden Park
-
Cincinnati, Ohio, Förenta staterna, 45211
- Oncology Hematology Care Inc-Mercy West
-
Cincinnati, Ohio, Förenta staterna, 45230
- Oncology Hematology Care Inc-Anderson
-
Cincinnati, Ohio, Förenta staterna, 45236
- Oncology Hematology Care Inc-Kenwood
-
Cincinnati, Ohio, Förenta staterna, 45247
- TriHealth Cancer Institute-Westside
-
Cincinnati, Ohio, Förenta staterna, 45255
- TriHealth Cancer Institute-Anderson
-
Columbus, Ohio, Förenta staterna, 43214
- Riverside Methodist Hospital
-
Columbus, Ohio, Förenta staterna, 43219
- The Mark H Zangmeister Center
-
Columbus, Ohio, Förenta staterna, 43214
- Columbus Oncology and Hematology Associates Inc
-
Columbus, Ohio, Förenta staterna, 43228
- Doctors Hospital
-
Columbus, Ohio, Förenta staterna, 43215
- Grant Medical Center
-
Columbus, Ohio, Förenta staterna, 43222
- Mount Carmel Health Center West
-
Columbus, Ohio, Förenta staterna, 43215
- Columbus NCI Community Oncology Research Program
-
Dayton, Ohio, Förenta staterna, 45406
- Good Samaritan Hospital - Dayton
-
Dayton, Ohio, Förenta staterna, 45409
- Miami Valley Hospital
-
Dayton, Ohio, Förenta staterna, 45415
- Miami Valley Hospital North
-
Dayton, Ohio, Förenta staterna, 45459
- Dayton NCI Community Oncology Research Program
-
Dayton, Ohio, Förenta staterna, 45415
- Dayton Physician LLC - Englewood
-
Delaware, Ohio, Förenta staterna, 43015
- Delaware Health Center-Grady Cancer Center
-
Delaware, Ohio, Förenta staterna, 43015
- Delaware Radiation Oncology
-
Delaware, Ohio, Förenta staterna, 43015
- Grady Memorial Hospital
-
Fairfield, Ohio, Förenta staterna, 45014
- Oncology Hematology Care Inc-Healthplex
-
Findlay, Ohio, Förenta staterna, 45840
- Blanchard Valley Hospital
-
Findlay, Ohio, Förenta staterna, 45840
- Armes Family Cancer Center
-
Findlay, Ohio, Förenta staterna, 45840
- Orion Cancer Care
-
Franklin, Ohio, Förenta staterna, 45005-1066
- Atrium Medical Center-Middletown Regional Hospital
-
Franklin, Ohio, Förenta staterna, 45005
- Dayton Physicians LLC-Atrium
-
Greenville, Ohio, Förenta staterna, 45331
- Wayne Hospital
-
Greenville, Ohio, Förenta staterna, 45331
- Dayton Physicians LLC-Wayne
-
Kettering, Ohio, Förenta staterna, 45429
- Kettering Medical Center
-
Kettering, Ohio, Förenta staterna, 45409
- Greater Dayton Cancer Center
-
Lancaster, Ohio, Förenta staterna, 43130
- Fairfield Medical Center
-
Lancaster, Ohio, Förenta staterna, 43130
- Lancaster Radiation Oncology
-
Lima, Ohio, Förenta staterna, 45804
- Lima Memorial Hospital
-
Marietta, Ohio, Förenta staterna, 45750
- Marietta Memorial Hospital
-
Maumee, Ohio, Förenta staterna, 43537
- Toledo Clinic Cancer Centers-Maumee
-
Maumee, Ohio, Förenta staterna, 43537
- Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
-
Medina, Ohio, Förenta staterna, 44256
- Summa Health Medina Medical Center
-
Middletown, Ohio, Förenta staterna, 45042
- Dayton Physicians LLC-Signal Point
-
Mount Vernon, Ohio, Förenta staterna, 43050
- Knox Community Hospital
-
Newark, Ohio, Förenta staterna, 43055
- Licking Memorial Hospital
-
Newark, Ohio, Förenta staterna, 43055
- Newark Radiation Oncology
-
Oregon, Ohio, Förenta staterna, 43616
- Saint Charles Hospital
-
Oregon, Ohio, Förenta staterna, 43616
- Toledo Clinic Cancer Centers-Oregon
-
Portsmouth, Ohio, Förenta staterna, 45662
- Southern Ohio Medical Center
-
Sidney, Ohio, Förenta staterna, 45365
- Dayton Physicians LLC-Wilson
-
Springfield, Ohio, Förenta staterna, 45504
- Springfield Regional Cancer Center
-
Springfield, Ohio, Förenta staterna, 45504
- Springfield Regional Medical Center
-
Sylvania, Ohio, Förenta staterna, 43560
- ProMedica Flower Hospital
-
Tiffin, Ohio, Förenta staterna, 44883
- Mercy Hospital of Tiffin
-
Toledo, Ohio, Förenta staterna, 43606
- ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
-
Toledo, Ohio, Förenta staterna, 43623
- Mercy Health - Saint Anne Hospital
-
Toledo, Ohio, Förenta staterna, 43623
- Toledo Clinic Cancer Centers-Toledo
-
Toledo, Ohio, Förenta staterna, 43614
- University of Toledo
-
Toledo, Ohio, Förenta staterna, 43617
- Toledo Community Hospital Oncology Program CCOP
-
Toledo, Ohio, Förenta staterna, 43608
- Mercy Health - Saint Vincent Hospital
-
Troy, Ohio, Förenta staterna, 45373
- Upper Valley Medical Center
-
Troy, Ohio, Förenta staterna, 45373
- Dayton Physicians LLC - Troy
-
Wauseon, Ohio, Förenta staterna, 43567
- Fulton County Health Center
-
West Chester, Ohio, Förenta staterna, 45069
- University of Cincinnati Cancer Center-West Chester
-
Westerville, Ohio, Förenta staterna, 43081
- Saint Ann's Hospital
-
Wpafb, Ohio, Förenta staterna, 45433
- Wright-Patterson Medical Center
-
Zanesville, Ohio, Förenta staterna, 43701
- Genesis Healthcare System Cancer Care Center
-
-
Oklahoma
-
Lawton, Oklahoma, Förenta staterna, 73505
- Cancer Centers of Southwest Oklahoma Research
-
Oklahoma City, Oklahoma, Förenta staterna, 73104
- University of Oklahoma Health Sciences Center
-
Tulsa, Oklahoma, Förenta staterna, 74136
- Natalie Warren Bryant Cancer Center at Saint Francis
-
Tulsa, Oklahoma, Förenta staterna, 74136
- Surgical Associates Inc
-
Tulsa, Oklahoma, Förenta staterna, 74146
- Warren Clinic Oncology-Tulsa
-
-
Oregon
-
Portland, Oregon, Förenta staterna, 97227
- Kaiser Permanente Northwest
-
-
Pennsylvania
-
Beaver, Pennsylvania, Förenta staterna, 15009
- UPMC-Heritage Valley Health System Beaver
-
Chadds Ford, Pennsylvania, Förenta staterna, 19317
- Christiana Care Health System-Concord Health Center
-
Danville, Pennsylvania, Förenta staterna, 17822
- Geisinger Medical Center
-
Easton, Pennsylvania, Förenta staterna, 18042
- Easton Hospital
-
Greensburg, Pennsylvania, Förenta staterna, 15601
- UPMC Cancer Centers - Arnold Palmer Pavilion
-
Harrisburg, Pennsylvania, Förenta staterna, 17109
- UPMC Pinnacle Cancer Center/Community Osteopathic Campus
-
Hazleton, Pennsylvania, Förenta staterna, 18201
- Geisinger Medical Center-Cancer Center Hazleton
-
Hershey, Pennsylvania, Förenta staterna, 17033-0850
- Penn State Milton S Hershey Medical Center
-
Jefferson Hills, Pennsylvania, Förenta staterna, 15025
- Jefferson Hospital
-
Johnstown, Pennsylvania, Förenta staterna, 15901
- UPMC-Johnstown/John P. Murtha Regional Cancer Center
-
Lewisburg, Pennsylvania, Förenta staterna, 17837
- Geisinger Medical Oncology-Lewisburg
-
Lewistown, Pennsylvania, Förenta staterna, 17044
- Lewistown Hospital
-
McKeesport, Pennsylvania, Förenta staterna, 15132
- UPMC Cancer Center at UPMC McKeesport
-
Monroeville, Pennsylvania, Förenta staterna, 15146
- Forbes Hospital
-
Moon Township, Pennsylvania, Förenta staterna, 15108
- UPMC Hillman Cancer Center in Coraopolis
-
Philadelphia, Pennsylvania, Förenta staterna, 19107
- Thomas Jefferson University Hospital
-
Philadelphia, Pennsylvania, Förenta staterna, 19114
- Jefferson Torresdale Hospital
-
Phoenixville, Pennsylvania, Förenta staterna, 19460
- Reading Hospital McGlinn Cancer Institute at Phoenixville
-
Pittsburgh, Pennsylvania, Förenta staterna, 15212
- Allegheny General Hospital
-
Pittsburgh, Pennsylvania, Förenta staterna, 15224
- West Penn Hospital
-
Pittsburgh, Pennsylvania, Förenta staterna, 15213
- UPMC-Magee Womens Hospital
-
Pittsburgh, Pennsylvania, Förenta staterna, 15232
- University of Pittsburgh Cancer Institute (UPCI)
-
Pittsburgh, Pennsylvania, Förenta staterna, 15232
- UPMC-Shadyside Hospital
-
Pittsburgh, Pennsylvania, Förenta staterna, 15213
- UPMC-Presbyterian Hospital
-
Pittsburgh, Pennsylvania, Förenta staterna, 15215
- UPMC-Saint Margaret
-
Pittsburgh, Pennsylvania, Förenta staterna, 15236
- UPMC Jefferson Regional Radiation Oncology
-
Pittsburgh, Pennsylvania, Förenta staterna, 15237
- UPMC-Passavant Hospital
-
Pittsburgh, Pennsylvania, Förenta staterna, 15243
- UPMC-Saint Clair Hospital Cancer Center
-
Pottsville, Pennsylvania, Förenta staterna, 17901
- Geisinger Cancer Services-Pottsville
-
Scranton, Pennsylvania, Förenta staterna, 18508
- Hematology and Oncology Associates of North East Pennsylvania
-
Seneca, Pennsylvania, Förenta staterna, 16346
- UPMC Cancer Center at UPMC Northwest
-
State College, Pennsylvania, Förenta staterna, 16801
- Geisinger Medical Group
-
Uniontown, Pennsylvania, Förenta staterna, 15401
- UPMC Uniontown Hospital Radiation Oncology
-
Washington, Pennsylvania, Förenta staterna, 15301
- UPMC Washington Hospital Radiation Oncology
-
West Chester, Pennsylvania, Förenta staterna, 19380
- Chester County Hospital
-
West Grove, Pennsylvania, Förenta staterna, 19390
- Jennersville Regional Hospital
-
West Reading, Pennsylvania, Förenta staterna, 19611
- Reading Hospital
-
Wilkes-Barre, Pennsylvania, Förenta staterna, 18711
- Geisinger Wyoming Valley/Henry Cancer Center
-
Williamsport, Pennsylvania, Förenta staterna, 17701
- UPMC Susquehanna
-
-
Rhode Island
-
Providence, Rhode Island, Förenta staterna, 02905
- Women and Infants Hospital
-
Warwick, Rhode Island, Förenta staterna, 02886
- Kent Hospital
-
-
South Carolina
-
Anderson, South Carolina, Förenta staterna, 29621
- AnMed Health Cancer Center
-
Boiling Springs, South Carolina, Förenta staterna, 29316
- Prisma Health Cancer Institute - Spartanburg
-
Easley, South Carolina, Förenta staterna, 29640
- Prisma Health Cancer Institute - Easley
-
Georgetown, South Carolina, Förenta staterna, 29440
- Tidelands Georgetown Memorial Hospital
-
Greenville, South Carolina, Förenta staterna, 29605
- Prisma Health Cancer Institute - Faris
-
Greenville, South Carolina, Förenta staterna, 29607
- Saint Francis Cancer Center
-
Greenville, South Carolina, Förenta staterna, 29615
- Prisma Health Cancer Institute - Eastside
-
Greenville, South Carolina, Förenta staterna, 29605
- Prisma Health Cancer Institute - Butternut
-
Greenville, South Carolina, Förenta staterna, 29601
- Saint Francis Hospital
-
Greenville, South Carolina, Förenta staterna, 29605
- Prisma Health Greenville Memorial Hospital
-
Greenville, South Carolina, Förenta staterna, 29601
- Greenville Health System Cancer Institute-Andrews
-
Greer, South Carolina, Förenta staterna, 29650
- Prisma Health Cancer Institute - Greer
-
Greer, South Carolina, Förenta staterna, 29651
- Gibbs Cancer Center-Pelham
-
Lancaster, South Carolina, Förenta staterna, 29720
- Carolina Blood and Cancer Care Associates PA-Lancaster
-
Rock Hill, South Carolina, Förenta staterna, 29732
- Carolina Blood and Cancer Care Associates PA
-
Seneca, South Carolina, Förenta staterna, 29672
- Prisma Health Cancer Institute - Seneca
-
Spartanburg, South Carolina, Förenta staterna, 29303
- Spartanburg Medical Center
-
Union, South Carolina, Förenta staterna, 29379
- SMC Center for Hematology Oncology Union
-
-
South Dakota
-
Sioux Falls, South Dakota, Förenta staterna, 57105
- Avera Cancer Institute
-
Sioux Falls, South Dakota, Förenta staterna, 57117-5134
- Sanford USD Medical Center - Sioux Falls
-
Sioux Falls, South Dakota, Förenta staterna, 57104
- Sanford Cancer Center Oncology Clinic
-
-
Tennessee
-
Chattanooga, Tennessee, Förenta staterna, 37404
- Memorial Hospital
-
Hixson, Tennessee, Förenta staterna, 37343
- Pulmonary Medicine Center of Chattanooga-Hixson
-
Jackson, Tennessee, Förenta staterna, 38301
- Jackson-Madison County General Hospital
-
Nashville, Tennessee, Förenta staterna, 37208
- Meharry Medical College
-
Ooltewah, Tennessee, Förenta staterna, 37363
- Memorial GYN Plus
-
-
Texas
-
Abilene, Texas, Förenta staterna, 79601
- Hendrick Medical Center
-
Houston, Texas, Förenta staterna, 77026-1967
- Lyndon Baines Johnson General Hospital
-
Houston, Texas, Förenta staterna, 77030
- Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
-
Houston, Texas, Förenta staterna, 77030
- Ben Taub General Hospital
-
Laredo, Texas, Förenta staterna, 78041
- Doctor's Hospital of Laredo
-
San Antonio, Texas, Förenta staterna, 78229
- University Hospital
-
San Antonio, Texas, Förenta staterna, 78229
- University of Texas Health Science Center at San Antonio
-
San Antonio, Texas, Förenta staterna, 78229
- Cancer Therapy and Research Center at The UT Health Science Center at San Antonio
-
-
Utah
-
Salt Lake City, Utah, Förenta staterna, 84112
- Huntsman Cancer Institute/University of Utah
-
-
Vermont
-
Berlin Corners, Vermont, Förenta staterna, 05602
- Central Vermont Medical Center/National Life Cancer Treatment
-
Burlington, Vermont, Förenta staterna, 05401
- University of Vermont Medical Center
-
Burlington, Vermont, Förenta staterna, 05405
- University of Vermont and State Agricultural College
-
-
Virginia
-
Fredericksburg, Virginia, Förenta staterna, 22401
- Fredericksburg Oncology Inc
-
Fredericksburg, Virginia, Förenta staterna, 22408
- Hematology Oncology Associates of Fredericksburg Inc
-
Mechanicsville, Virginia, Förenta staterna, 23116
- Bon Secours Memorial Regional Medical Center
-
Midlothian, Virginia, Förenta staterna, 23114
- Bon Secours Saint Francis Medical Center
-
Richmond, Virginia, Förenta staterna, 23226
- Bon Secours Saint Mary's Hospital
-
Richmond, Virginia, Förenta staterna, 23298
- VCU Massey Comprehensive Cancer Center
-
South Hill, Virginia, Förenta staterna, 23970
- VCU Community Memorial Health Center
-
Winchester, Virginia, Förenta staterna, 22601
- Shenandoah Oncology PC
-
-
Washington
-
Auburn, Washington, Förenta staterna, 98001
- MultiCare Auburn Medical Center
-
Bainbridge Island, Washington, Förenta staterna, 98110
- Virginia Mason Bainbridge Island Medical Center
-
Bellevue, Washington, Förenta staterna, 98004
- Overlake Medical Center
-
Burien, Washington, Förenta staterna, 98166
- Highline Medical Center-Main Campus
-
Centralia, Washington, Förenta staterna, 98531
- Providence Regional Cancer System-Centralia
-
Enumclaw, Washington, Förenta staterna, 98022
- Saint Elizabeth Hospital
-
Everett, Washington, Förenta staterna, 98201
- Providence Regional Cancer Partnership
-
Federal Way, Washington, Förenta staterna, 98002
- Virginia Mason Federal Way Medical Center
-
Federal Way, Washington, Förenta staterna, 98003
- Saint Francis Hospital
-
Gig Harbor, Washington, Förenta staterna, 98332
- Tacoma/Valley Radiation Oncology Centers-Gig Harbor
-
Gig Harbor, Washington, Förenta staterna, 98335
- MultiCare Gig Harbor Medical Park
-
Kennewick, Washington, Förenta staterna, 99336
- Northwest Cancer Clinic
-
Lacey, Washington, Förenta staterna, 98503
- Providence Regional Cancer System-Lacey
-
Lakewood, Washington, Förenta staterna, 98499
- Saint Clare Hospital
-
Lynnwood, Washington, Förenta staterna, 98036
- Virginia Mason Lynnwood Medical Center
-
Olympia, Washington, Förenta staterna, 98506-5166
- Providence - Saint Peter Hospital
-
Olympia, Washington, Förenta staterna, 98507
- Capital Medical Center
-
Port Townsend, Washington, Förenta staterna, 98368
- Jefferson Healthcare
-
Poulsbo, Washington, Förenta staterna, 98370
- Harrison HealthPartners Hematology and Oncology-Poulsbo
-
Poulsbo, Washington, Förenta staterna, 98370
- Peninsula Cancer Center
-
Puyallup, Washington, Förenta staterna, 98372
- MultiCare Good Samaritan Hospital
-
Puyallup, Washington, Förenta staterna, 98372
- Tacoma/Valley Radiation Oncology Centers-Puyallup
-
Seattle, Washington, Förenta staterna, 98101
- Virginia Mason Medical Center
-
Silverdale, Washington, Förenta staterna, 98383
- Saint Michael Cancer Center
-
Tacoma, Washington, Förenta staterna, 98405
- Northwest Medical Specialties PLLC
-
Tacoma, Washington, Förenta staterna, 98405
- MultiCare Tacoma General Hospital
-
Tacoma, Washington, Förenta staterna, 98405
- Tacoma/Valley Radiation Oncology Centers-Saint Joe's
-
Tacoma, Washington, Förenta staterna, 97405
- Tacoma/Valley Radiation Oncology Centers-Jackson Hall
-
Tacoma, Washington, Förenta staterna, 98405
- Franciscan Research Center-Northwest Medical Plaza
-
Tacoma, Washington, Förenta staterna, 98405
- MultiCare Allenmore Hospital
-
Tacoma, Washington, Förenta staterna, 98405
- Northwest NCI Community Oncology Research Program
-
Tacoma, Washington, Förenta staterna, 98405
- Saint Joseph Medical Center
-
-
West Virginia
-
Bridgeport, West Virginia, Förenta staterna, 26330
- United Hospital Center
-
Charleston, West Virginia, Förenta staterna, 25304
- West Virginia University Charleston Division
-
Huntington, West Virginia, Förenta staterna, 25701
- Edwards Comprehensive Cancer Center
-
Martinsburg, West Virginia, Förenta staterna, 25401
- WVUH-Berkely Medical Center
-
Morgantown, West Virginia, Förenta staterna, 26506
- West Virginia University Healthcare
-
Morgantown, West Virginia, Förenta staterna, 26505
- Monongalia Hospital
-
Parkersburg, West Virginia, Förenta staterna, 26101
- Camden Clark Medical Center
-
-
Wisconsin
-
Burlington, Wisconsin, Förenta staterna, 53105
- Aurora Cancer Care-Southern Lakes VLCC
-
Chippewa Falls, Wisconsin, Förenta staterna, 54729
- Marshfield Clinic-Chippewa Center
-
Eau Claire, Wisconsin, Förenta staterna, 54701
- HSHS Sacred Heart Hospital
-
Eau Claire, Wisconsin, Förenta staterna, 54701
- Marshfield Clinic Cancer Center at Sacred Heart
-
Fond du Lac, Wisconsin, Förenta staterna, 54937
- Aurora Health Center-Fond du Lac
-
Germantown, Wisconsin, Förenta staterna, 53022
- Aurora Health Care Germantown Health Center
-
Grafton, Wisconsin, Förenta staterna, 53024
- Aurora Cancer Care-Grafton
-
Green Bay, Wisconsin, Förenta staterna, 54311
- Aurora BayCare Medical Center
-
Green Bay, Wisconsin, Förenta staterna, 54301
- Bellin Memorial Hospital
-
Janesville, Wisconsin, Förenta staterna, 53548
- Mercyhealth Hospital and Cancer Center - Janesville
-
Kenosha, Wisconsin, Förenta staterna, 53142
- Aurora Cancer Care-Kenosha South
-
Ladysmith, Wisconsin, Förenta staterna, 54848
- Marshfield Medical Center - Ladysmith
-
Marinette, Wisconsin, Förenta staterna, 54143
- Aurora Bay Area Medical Group-Marinette
-
Marshfield, Wisconsin, Förenta staterna, 54449
- Marshfield Medical Center-Marshfield
-
Marshfield, Wisconsin, Förenta staterna, 54449
- Marshfield Medical Center
-
Milwaukee, Wisconsin, Förenta staterna, 53226
- Medical College of Wisconsin
-
Milwaukee, Wisconsin, Förenta staterna, 53209
- Aurora Cancer Care-Milwaukee
-
Milwaukee, Wisconsin, Förenta staterna, 53215
- Aurora Saint Luke's Medical Center
-
Milwaukee, Wisconsin, Förenta staterna, 53233
- Aurora Sinai Medical Center
-
Minocqua, Wisconsin, Förenta staterna, 54548
- Marshfield Medical Center - Minocqua
-
New Richmond, Wisconsin, Förenta staterna, 54017
- Cancer Center of Western Wisconsin
-
Oshkosh, Wisconsin, Förenta staterna, 54904
- Vince Lombardi Cancer Clinic - Oshkosh
-
Racine, Wisconsin, Förenta staterna, 53406
- Aurora Cancer Care-Racine
-
Rhinelander, Wisconsin, Förenta staterna, 54501
- Saint Mary's Hospital
-
Rhinelander, Wisconsin, Förenta staterna, 54501
- Aspirus Cancer Care - James Beck Cancer Center
-
Rice Lake, Wisconsin, Förenta staterna, 54868
- Marshfield Medical Center-Rice Lake
-
Sheboygan, Wisconsin, Förenta staterna, 53081
- Vince Lombardi Cancer Clinic-Sheboygan
-
Stevens Point, Wisconsin, Förenta staterna, 54481
- Aspirus Cancer Care - Stevens Point
-
Summit, Wisconsin, Förenta staterna, 53066
- Aurora Medical Center in Summit
-
Two Rivers, Wisconsin, Förenta staterna, 54241
- Vince Lombardi Cancer Clinic-Two Rivers
-
Waukesha, Wisconsin, Förenta staterna, 53188
- Aurora Cancer Care-Waukesha
-
Wausau, Wisconsin, Förenta staterna, 54401
- Marshfield Clinic-Wausau Center
-
Wauwatosa, Wisconsin, Förenta staterna, 53226
- Aurora Cancer Care-Milwaukee West
-
West Allis, Wisconsin, Förenta staterna, 53227
- Aurora West Allis Medical Center
-
Weston, Wisconsin, Förenta staterna, 54476
- Marshfield Medical Center - Weston
-
Weston, Wisconsin, Förenta staterna, 54476
- Diagnostic and Treatment Center
-
Weston, Wisconsin, Förenta staterna, 54476
- Ascension Saint Clare's Hospital
-
Wisconsin Rapids, Wisconsin, Förenta staterna, 54494
- Marshfield Clinic - Wisconsin Rapids Center
-
-
Wyoming
-
Casper, Wyoming, Förenta staterna, 82609
- Rocky Mountain Oncology
-
Cheyenne, Wyoming, Förenta staterna, 82001
- Cheyenne Regional Medical Center-West
-
Cody, Wyoming, Förenta staterna, 82414
- Big Horn Basin Cancer Center
-
Cody, Wyoming, Förenta staterna, 82414
- Billings Clinic-Cody
-
Sheridan, Wyoming, Förenta staterna, 82801
- Welch Cancer Center
-
-
-
-
-
San Juan, Puerto Rico, 00936
- San Juan City Hospital
-
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Deltagandekriterier
Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.
Urvalskriterier
Åldrar som är berättigade till studier
18 år och äldre (Vuxen, Äldre vuxen)
Tar emot friska volontärer
Nej
Kön som är behöriga för studier
Kvinna
Beskrivning
Inclusion Criteria:
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Patients should have a life expectancy of at least 10 years, excluding their diagnosis of breast cancer; (comorbid conditions should be taken into consideration, but not the diagnosis of breast cancer)
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Women of reproductive potential must agree to use an effective non-hormonal method of contraception during study therapy (chemotherapy, trastuzumab, pertuzumab, and estrogen deprivation therapy) and for at least 7 months after the last dose of study therapy
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Submission of tumor samples is required for all patients; the local pathology department policy regarding release of tumor samples must be considered in the screening process; patients whose tumor samples are located in a pathology department that by policy will not submit any samples for research purposes should not be approached for participation in the B-52 trial
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The patient must have signed and dated an Institutional Review Board (IRB)-approved consent form that conforms to federal and institutional guidelines
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The patient must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
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Clinical staging for the primary tumor can be cT1c (must be 2.0 cm) or T2-T4 if clinically node negative; if the regional lymph nodes are cN1 and cytologically or histologically positive or if cN2-N3 with or without a biopsy, the primary breast tumor can be cT0-T4
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The diagnosis of invasive adenocarcinoma of the breast must have been made by core needle biopsy
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Ipsilateral axillary lymph nodes must be evaluated by imaging (mammogram, ultrasound, and/or magnetic resonance imaging [MRI]) within 6 weeks prior to randomization; if suspicious or abnormal, fine needle aspirate (FNA) or core biopsy is recommended, also within 6 weeks prior to randomization; findings of these evaluations will be used to determine the nodal status prior to randomization:
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Nodal status - negative
- Imaging of the axilla is negative
- Imaging is suspicious or abnormal but the FNA or core biopsy of the questionable node(s) on imaging is negative
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Nodal status - positive
- FNA or core biopsy of the node(s) is cytologically or histologically suspicious or positive
- Imaging is suspicious or abnormal but FNA or core biopsy was not performed
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Patients may be premenopausal or postmenopausal at the time of randomization; for study purposes, postmenopausal is defined as:
- Age 56 or older with no spontaneous menses for at least 12 months prior to study entry; or
- Age 55 or younger with no spontaneous menses for at least 12 months prior to study entry (e.g., spontaneous or secondary to hysterectomy) and with a documented estradiol level in the postmenopausal range according to local institutional/laboratory standard; or
- Documented bilateral oophorectomy
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The tumor must have been determined to be HER2-postive as follows:
- Immunohistochemistry (IHC) 3+ or
- In situ hybridization (ISH)-positive (defined by ratio of HER2 to circulating endothelial progenitors [CEP]17 >= 2.0 or HER2 gene copy number >= 6 per nucleus)
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The tumor must have been determined to be estrogen receptor (ER) and/or progesterone (PgR) positive assessed by current American Society of Clinical Oncology (ASCO)/College of American Pathologist (CAP) guideline recommendations for hormone receptor testing; patients with >= 1% ER or PgR staining by IHC are considered positive
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Absolute neutrophil count (ANC) must be >= 1200/mm^3
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Platelet count must be >= 100,000/mm^3
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Hemoglobin must be >= 10 g/dL
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Total bilirubin must be =< upper limit of normal (ULN) for the lab unless the patient has a bilirubin elevation > ULN to 1.5 x ULN due to Gilbert's disease or similar syndrome involving slow conjugation of bilirubin
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Alkaline phosphatase must be =< 2.5 x ULN for the lab
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Aspartate aminotransferase (AST) must be =< 1.5 x ULN for the lab
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Alkaline phosphatase and AST may not both be > the ULN; for example, if the alkaline phosphatase is > the ULN but =< 2.5 x ULN, the AST must be =< the ULN; if the AST is > the ULN but =< 1.5 x ULN, the alkaline phosphatase must be =< ULN; Note: If alanine aminotransferase (ALT) is performed instead of AST (per institution's standard practice), the ALT value must be =< 1.5 x ULN; if both were performed, the AST must be =< 1.5 x ULN
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Patients with AST or alkaline phosphatase > ULN are eligible for inclusion in the study if liver imaging (computed tomography [CT], MRI, positron emission tomography [PET]-CT, or PET scan) performed within 6 weeks prior to randomization does not demonstrate metastatic disease and the requirements are met
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Patients with alkaline phosphatase that is > ULN but =< 2.5 x ULN or unexplained bone pain are eligible for inclusion in the study if a bone scan, PET-CT scan, or PET scan performed within 6 weeks prior to randomization does not demonstrate metastatic disease
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Within 6 weeks prior to randomization, the most recent serum creatinine must be =< ULN or measured or calculated creatinine clearance must be > 60 mL/min
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Left ventricular ejection fraction (LVEF) assessment must be performed within 90 days prior to randomization; (LVEF assessment performed by 2-dimensional [2-D] echocardiogram is preferred; however, multi gated acquisition scan [MUGA] scan may be substituted based on institutional preferences); the LVEF must be >= 50% regardless of the cardiac imaging facility's lower limit of normal; note: since the pre-entry LVEF serves as the baseline for comparing subsequent LVEF assessments, it is critical that this baseline study be an accurate assessment; if the baseline LVEF is > 65%, the investigator is encouraged to have the accuracy of the initial LVEF result confirmed and repeat the test if the accuracy is uncertain
Exclusion Criteria:
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FNA alone to diagnose the breast cancer
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Excisional biopsy or lumpectomy performed prior to randomization
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Surgical axillary staging procedure prior to randomization; pre-neoadjuvant therapy sentinel node biopsy is not permitted
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Definitive clinical or radiologic evidence of metastatic disease; (chest imaging [mandatory for all patients] and other imaging [if required] must have been performed within 90 days prior to randomization)
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Synchronous bilateral invasive breast cancer
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Synchronous or previous contralateral invasive breast cancer; (patients with synchronous and/or previous contralateral ductal carcinoma in situ [DCIS] or lobular carcinoma in situ [LCIS] are eligible)
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Any previous history of ipsilateral invasive breast cancer or ipsilateral DCIS; (patients with synchronous or previous ipsilateral LCIS are eligible)
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Treatment including radiation therapy (RT), chemotherapy, targeted therapy, or endocrine therapy for the currently diagnosed breast cancer prior to randomization
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Previous endocrine therapy such as raloxifene or tamoxifen (or other selective estrogen receptor modulator [SERM]) or an aromatase inhibitor for any malignancy
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Previous therapy with anthracycline, taxanes, carboplatin, trastuzumab, or other HER2 targeted therapies for any malignancy
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Any sex hormonal therapy, e.g., birth control pills, ovarian hormone replacement therapy, etc. (these patients are eligible if this therapy is discontinued prior to randomization)
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History of non-breast malignancies (except for in situ cancers treated only by local excision and basal cell and squamous cell carcinomas of the skin) within 5 years prior to randomization
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Cardiac disease (history of and/or active disease) that would preclude the use of the drugs included in the treatment regimens; this includes but is not confined to:
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Active cardiac disease:
- Angina pectoris that requires the use of anti-anginal medication;
- Ventricular arrhythmias except for benign premature ventricular contractions;
- Supraventricular and nodal arrhythmias requiring a pacemaker or not controlled with medication;
- Conduction abnormality requiring a pacemaker;
- Valvular disease with documented compromise in cardiac function; and
- Symptomatic pericarditis
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History of cardiac disease:
- Myocardial infarction documented by elevated cardiac enzymes or persistent regional wall abnormalities on assessment of left ventricular (LV) function;
- History of documented congestive heart failure (CHF); and
- Documented cardiomyopathy
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Uncontrolled hypertension defined as sustained systolic blood pressure (BP) > 150 mmHg or diastolic BP > 90 mmHg; (patients with initial BP elevations are eligible if initiation or adjustment of BP medication lowers pressure to meet entry criteria)
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Active hepatitis B or hepatitis C with abnormal liver function tests
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Intrinsic lung disease resulting in dyspnea
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Poorly controlled diabetes mellitus
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Active infection or chronic infection requiring chronic suppressive antibiotics
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Patients known to be human immunodeficiency virus (HIV) positive with a baseline cluster of differentiation (CD)4 count of < 250 cells/mm^3 or have a history of acquired immune deficiency syndrome (AIDS) indicator conditions; patients taking anti-retroviral therapy that may have a potential overlapping toxicity with the study therapy are not eligible
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Nervous system disorder (paresthesia, peripheral motor neuropathy, or peripheral sensory neuropathy) >= grade 2, per the Common Terminology Criteria for Adverse Events version 4.0 (CTCAE v4.0)
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Malabsorption syndrome, ulcerative colitis, resection of the stomach or small bowel, or other disease significantly affecting gastrointestinal function
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Other non-malignant systemic disease that would preclude treatment with any of the treatment regimens or would prevent required follow-up
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Conditions that would prohibit administration of corticosteroids
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Chronic daily treatment with corticosteroids with a dose of >= 10 mg/day methylprednisolone equivalent (excluding inhaled steroids)
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Known hypersensitivity to any of the study drugs or any of the ingredients or excipients of these drugs (e.g., polysorbate 80), including sensitivity to benzyl alcohol
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Pregnancy or lactation at the time of study entry; (note: pregnancy testing must be performed within 2 weeks prior to randomization according to institutional standards for women of childbearing potential)
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Psychiatric or addictive disorders or other conditions that, in the opinion of the investigator, would preclude the patient from meeting the study requirements
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Use of any investigational product within 30 days prior to randomization
Studieplan
Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Behandling
- Tilldelning: Randomiserad
- Interventionsmodell: Parallellt uppdrag
- Maskning: Ingen (Open Label)
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
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Aktiv komparator: Arm I (combination chemotherapy, surgery, radiation)
NEOADJUVANT: Patients receive docetaxel IV over 60 minutes, carboplatin IV over 30-60 minutes, trastuzumab IV over 30-90 minutes, and pertuzumab IV over 30-60 on day 1. Treatment repeats every 21 days for up to 6 courses in the absence of disease progression or unacceptable toxicity. Patients enrolled after Amendment #4 undergo 2 core biopsies prior to course 3 of treatment. SURGERY: Patients undergo lumpectomy or mastectomy. RADIATION: Patients undergo whole breast irradiation within 8 weeks following surgery. ADJUVANT: Patients receive trastuzumab IV over 30-60 minutes every 21 days for up to 1 year. |
Given IV
Andra namn:
Given IV
Andra namn:
Correlative studies Ancillary studies
Andra namn:
Given IV
Andra namn:
Undergo 2 core biopsies
Andra namn:
Given IV
Andra namn:
Undergo lumpectomy or mastectomy Undergo whole breast irradiation |
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Experimentell: Arm II (chemo, estrogen deprivation, surgery, radiation)
NEOADJUVANT: All patients receive docetaxel, carboplatin, trastuzumab, and pertuzumab as in arm I. Premenopausal patients also receive goserelin acetate SC every 28 days until surgery and aromatase inhibition therapy at the investigator's discretion daily until 1 day before surgery. Postmenopausal patients receive aromatase inhibition therapy at the investigator's discretion daily until 1 day before surgery. Patients enrolled after Amendment #4 undergo 2 core biopsies prior to course 3 of treatment. SURGERY: Patients undergo lumpectomy or mastectomy. RADIATION: Patients undergo whole breast irradiation within 8 weeks following surgery. ADJUVANT: Patients receive trastuzumab IV over 30-60 minutes every 21 days for up to 1 year. |
Given IV
Andra namn:
Given IV
Andra namn:
Correlative studies Ancillary studies
Andra namn:
Given IV
Andra namn:
Undergo 2 core biopsies
Andra namn:
Given IV
Andra namn:
Undergo lumpectomy or mastectomy Undergo whole breast irradiation Given at the investigator's discretion
Andra namn:
Given SC
Andra namn:
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Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
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Percent of Patients With Pathological Complete Response (pCR) in the Breast and Post Therapy Lymph Nodes
Tidsram: Up to 2.8 years (when all patients completed primary breast surgery)
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Proportion of patients with pCR evaluated histologically, and defined as the absence of any invasive component in the resected breast specimen and all resected lymph nodes following completion of neoadjuvant therapy. |
Up to 2.8 years (when all patients completed primary breast surgery)
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Sekundära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
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Percent of Patients With Pathologic Complete Response (pCR) in the Breast
Tidsram: Up to 2.8 years (when all patients completed primary breast surgery)
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Proportion of patients with pCR in the breast, defined as the absence of any invasive component in the resected breast specimen. |
Up to 2.8 years (when all patients completed primary breast surgery)
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Recurrence Free Interval (RFI)
Tidsram: Time from surgery to invasive local, regional or distant recurrence, or death from breast cancer for patients with operable disease and for patients with inoperable progressive disease, assessed up to 8.4 years
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Kaplan-Meier estimates of the percentages of patients free from recurrence. |
Time from surgery to invasive local, regional or distant recurrence, or death from breast cancer for patients with operable disease and for patients with inoperable progressive disease, assessed up to 8.4 years
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Overall Survival (OS)
Tidsram: Time from randomization until death from any cause, assessed up to 8.4 years
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Kaplan-Meier estimates of the percentages of patients surviving. |
Time from randomization until death from any cause, assessed up to 8.4 years
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Second Primary Cancer of Any Type
Tidsram: Time from randomization to the development of a second primary invasive cancer of any site excluding squamous and basal cell carcinoma of the skin, assessed up to 8.4 years
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Number of second primary cancers for the two treatment groups |
Time from randomization to the development of a second primary invasive cancer of any site excluding squamous and basal cell carcinoma of the skin, assessed up to 8.4 years
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Percent of Patients With Pathological Complete Response (pCR) in the Breast and Post Therapy Lymph Nodes by Menopausal Status
Tidsram: Up to 2.8 years (when all patients completed primary breast surgery)
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Proportion of patients with pCR evaluated histologically, and defined as the absence of any invasive component in the resected breast specimen and all resected lymph nodes following completion of neoadjuvant therapy calculated separately for premenopausal and postmenopausal women. |
Up to 2.8 years (when all patients completed primary breast surgery)
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Patterns of Recurrence Free Interval (RFI) by Menopausal Status
Tidsram: Time from surgery to invasive local, regional or distant recurrence, or death from breast cancer for patients with operable disease and for patients with inoperable progressive disease, assessed up to 5 years
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Kaplan-Meier estimates of the percentages of patients free from recurrence by menopausal status. |
Time from surgery to invasive local, regional or distant recurrence, or death from breast cancer for patients with operable disease and for patients with inoperable progressive disease, assessed up to 5 years
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Patterns of Overall Survival (OS) by Menopausal Status
Tidsram: Time from randomization until death from any cause, assessed up to 5 years
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Kaplan-Meier estimates of the percentages of patients surviving by menopausal status. |
Time from randomization until death from any cause, assessed up to 5 years
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Percentage of Participants With Cardiac Toxicity Categorized According to National Cancer Institute CTCAE Version 4.0
Tidsram: Up to 6 weeks post surgery
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Percentage of patients with grade 1 or higher toxicity from the Cardiac Disorders System Organ Class. |
Up to 6 weeks post surgery
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Median Percentage of Tumor-infiltrating Lymphocytes (sTILS)
Tidsram: 2.8 years
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Percentage of Tumor-infiltrating lymphocytes present in the stroma in tissue specimen. |
2.8 years
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Change in Endocrine-related Symptoms Using Breast Cancer Prevention Trial (BCPT) Symptom Checklist
Tidsram: The outcome measure was assessed and is presented at three time points included baseline, Prior to cycle 4 (approximately 77 days), and 2-4 weeks after the last dose of chemotherapy prior to surgery (approximately 133-147 days)
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The Breast Cancer Prevention Trial (BCPT) symptom checklist contains 17 endocrine-related symptoms and problems. For each item, the patient was asked how bothersome the problem or symptom was during the past four weeks. Possible answers ranged from not at all (1) to extremely (5). The summary score was calculated for each participant as the average severity of all 17 items. The total mean summary score was calculated as the average summary score by treatment group. The range is 1-5 with higher scores indicating worse outcome. |
The outcome measure was assessed and is presented at three time points included baseline, Prior to cycle 4 (approximately 77 days), and 2-4 weeks after the last dose of chemotherapy prior to surgery (approximately 133-147 days)
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Samarbetspartners och utredare
Det är här du hittar personer och organisationer som är involverade i denna studie.
Sponsor
Samarbetspartners
Utredare
- Huvudutredare: Mothaffar F Rimawi, NRG Oncology
Studieavstämningsdatum
Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.
Studera stora datum
Studiestart (Faktisk)
18 februari 2014
Primärt slutförande (Faktisk)
31 oktober 2016
Avslutad studie (Faktisk)
30 juni 2025
Studieregistreringsdatum
Först inskickad
2 december 2013
Först inskickad som uppfyllde QC-kriterierna
2 december 2013
Första postat (Beräknad)
6 december 2013
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
6 oktober 2026
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
15 september 2026
Senast verifierad
1 september 2026
Mer information
Termer relaterade till denna studie
Ytterligare relevanta MeSH-villkor
- Neoplasmer efter plats
- Neoplasmer
- Hudsjukdomar
- Bröstsjukdomar
- Hud- och bindvävssjukdomar
- Bröstneoplasmer
- Läkemedels fysiologiska effekter
- Molekylära mekanismer för farmakologisk verkan
- Hormoner
- Hormoner, hormonsubstitut och hormonantagonister
- Enzyminhibitorer
- Steroidsyntesinhibitorer
- Hormonantagonister
- Östrogenantagonister
- Hypofyshormonfrisättande hormoner
- Hypotalamiska hormoner
- Peptidhormoner
- Neuropeptider
- Peptider
- Aminosyror, peptider och proteiner
- Oligopeptider
- Nervvävnadsproteiner
- Proteiner
- Organiska kemikalier
- Farmakologiska åtgärder
- Kemiska åtgärder och användningar
- Kolväten
- Cykloparaffiner
- Kolväten, alicyklisk
- Kolväten, cykliska
- Terpener
- Antikroppar, monoklonal, humaniserad
- Antikroppar, monoklonal
- Antikroppar
- Immunglobuliner
- Immunoproteiner
- Blodproteiner
- Serumglobuliner
- Globuliner
- Koordinationskomplex
- Taxoids
- Cyklodekaner
- Gentare
- Gonadotropinfrisättande hormon
- Docetaxel
- Trastuzumab
- Karboplatin
- Goserelin
- Aromatashämmare
- pertuzumab
- 2C4 -antikropp
- Ct-p6
- PF-05280014
- trastuzumab biosimilar hlx02
- Ogivri
- Oxusen
Andra studie-ID-nummer
- NCI-2013-02228
- U10CA180868 (U.S.S. NIH-anslag/kontrakt)
- U10CA012027 (U.S.S. NIH-anslag/kontrakt)
- NCI-2013-02228 (Registeridentifierare: CTRP (Clinical Trial Reporting Program))
- NSABP-B-52 (Annan identifierare: CTEP)
- NSABP-B-52 (Annan identifierare: NRG Oncology)
Denna information hämtades direkt från webbplatsen clinicaltrials.gov utan några ändringar. Om du har några önskemål om att ändra, ta bort eller uppdatera dina studieuppgifter, vänligen kontakta register@clinicaltrials.gov. Så snart en ändring har implementerats på clinicaltrials.gov, kommer denna att uppdateras automatiskt även på vår webbplats .