- ICH GCP
- Amerikanska kliniska prövningsregistret
- Klinisk prövning NCT07810595
Three Breathing Techniques for Heart Rate Variability, Attention, Reaction Time, and Anxiety
Comparative Effects of Three Breathing Techniques on Heart Rate Variability, Attention, Reaction Time, and Anxiety in Healthy Adults: A Randomized Controlled Trial
Studieöversikt
Status
Betingelser
Intervention / Behandling
Detaljerad beskrivning
Healthy adults aged 18-40 years were recruited using convenience sampling and randomly assigned in a 1:1:1 ratio to Mindfulness Breathing, Box Breathing, or Nadi Shodhana Pranayama. Participants received an individual face-to-face training session delivered by the same physiotherapist, practiced their assigned breathing technique under supervision until correct performance was confirmed, and subsequently performed daily home-based practice for six weeks using standardized instructional videos. Daily WhatsApp reminders containing the appropriate video link were sent to support adherence.
Heart rate variability was assessed using a Polar H10 heart rate monitor with 5-minute resting recordings analyzed using Kubios HRV software. Attention performance was measured using the Digit Cancellation Test, reaction time was assessed using the BlazePod wireless reaction system, and anxiety outcomes were evaluated using the State-Trait Anxiety Inventory. Assessments were performed at baseline and after six weeks.
Studietyp
Inskrivning (Faktisk)
Fas
- Inte tillämpbar
Kontakter och platser
Studieorter
-
-
Kagıthane
-
Istanbul, Kagıthane, Turkiet (Türkiye)
- Istanbul Atlas University
-
-
Deltagandekriterier
Urvalskriterier
Åldrar som är berättigade till studier
- Vuxen
Tar emot friska volontärer
Beskrivning
Inclusion Criteria:
- Healthy adults aged 18 to 40 years.
- Ability to provide written informed consent.
- Ownership of a smartphone with internet access.
- Willingness to participate in daily breathing practice for six weeks.
Exclusion Criteria:
- Respiratory disease.
- History of lung transplantation.
- Pregnancy or suspected pregnancy.
- Previous experience with yoga, Qigong, breath therapy, or other structured breathing practices.
Studieplan
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Grundläggande vetenskap
- Tilldelning: Randomiserad
- Interventionsmodell: Parallellt uppdrag
- Maskning: Enda
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
|---|---|
|
Aktiv komparator: Mindfulness Breathing
Participants practiced mindful awareness of their natural breathing without intentionally altering breathing rhythm during daily home sessions for six weeks.
|
Participants received an individual face-to-face training session from the same physiotherapist, practiced under supervision until correct performance was confirmed, and subsequently performed daily home-based mindfulness breathing for six weeks using standardized instructional videos and daily WhatsApp reminders.
|
|
Experimentell: Box Breathing
Participants performed a structured 4-4-4-4 breathing cycle consisting of 4 seconds of inhalation, 4 seconds of breath holding, 4 seconds of exhalation, and a 4-second post-exhalation pause during daily home practice for six weeks.
|
Participants received standardized face-to-face instruction and performed daily home-based Box Breathing using a 4-second inhalation, 4-second breath hold, 4-second exhalation, and 4-second pause for six weeks, supported by instructional videos and daily WhatsApp reminders.
|
|
Experimentell: Nadi Shodhana Pranayama
Participants performed alternate nostril breathing with controlled inhalation and exhalation while maintaining a slow and rhythmic breathing pattern during daily home practice for six weeks.
|
Participants received standardized face-to-face instruction and performed daily home-based alternate nostril breathing for six weeks using instructional videos and daily WhatsApp reminders.
|
Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Resting Heart Rate
Tidsram: Baseline and Week 6
|
Resting heart rate (beats per minute) measured from a 5-minute seated recording using the Polar H10 heart rate monitor (Polar Electro, Kempele, Finland).
|
Baseline and Week 6
|
|
Root Mean Square of Successive Differences (RMSSD)
Tidsram: Baseline and Week 6
|
RMSSD (milliseconds), a vagally mediated heart rate variability parameter, derived from 5-minute RR interval recordings analyzed using Kubios HRV software.
|
Baseline and Week 6
|
|
Respiratory Rate
Tidsram: Baseline and Week 6
|
Respiratory rate (breaths per minute) obtained from the 5-minute Polar H10 recording.
|
Baseline and Week 6
|
Sekundära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
BlazePod Reaction Time
Tidsram: Baseline and Week 6
|
Reaction time assessed using a single BlazePod wireless light-based reaction system with the dominant hand.
The system recorded average reaction time, number of successful responses, and number of errors.
|
Baseline and Week 6
|
|
Digit Cancellation Test Score
Tidsram: Baseline and Week 6
|
Attention performance is assessed using the Digit Cancellation Test by recording the number of correctly identified targets within 30 seconds.
Higher scores indicate better sustained and selective attention performance.
|
Baseline and Week 6
|
|
Anxiety
Tidsram: Baseline and Week 6
|
Anxiety assessed using the State-Trait Anxiety Inventory.
Scores range from 20 to 80, with higher scores indicating greater state anxiety.
|
Baseline and Week 6
|
Samarbetspartners och utredare
Sponsor
Studieavstämningsdatum
Studera stora datum
Studiestart (Faktisk)
Primärt slutförande (Faktisk)
Avslutad studie (Faktisk)
Studieregistreringsdatum
Först inskickad
Först inskickad som uppfyllde QC-kriterierna
Första postat (Faktisk)
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
Senast verifierad
Mer information
Termer relaterade till denna studie
Nyckelord
Ytterligare relevanta MeSH-villkor
Andra studie-ID-nummer
- E 22686390 050.99 62685
Plan för individuella deltagardata (IPD)
Planerar du att dela individuella deltagardata (IPD)?
IPD-planbeskrivning
Läkemedels- och apparatinformation, studiedokument
Studerar en amerikansk FDA-reglerad läkemedelsprodukt
Studerar en amerikansk FDA-reglerad produktprodukt
Denna information hämtades direkt från webbplatsen clinicaltrials.gov utan några ändringar. Om du har några önskemål om att ändra, ta bort eller uppdatera dina studieuppgifter, vänligen kontakta register@clinicaltrials.gov. Så snart en ändring har implementerats på clinicaltrials.gov, kommer denna att uppdateras automatiskt även på vår webbplats .