A web-based study of the relationship of duration of insulin pump infusion set use and fasting blood glucose level in adults with type 1 diabetes
Alysa J Sampson Perrin, Russell C Guzzetta, Kellee M Miller, Nicole C Foster, Anna Lee, Joyce M Lee, Jennifer M Block, Roy W Beck, T1D Exchange Clinic Network, Alysa J Sampson Perrin, Russell C Guzzetta, Kellee M Miller, Nicole C Foster, Anna Lee, Joyce M Lee, Jennifer M Block, Roy W Beck, T1D Exchange Clinic Network
Abstract
Background: To evaluate the impact of infusion set use duration on glycemic control, we conducted an Internet-based study using the T1D Exchange's online patient community, Glu ( myGlu.org ).
Subjects and methods: For 14 days, 243 electronically consented adults with type 1 diabetes (T1D) entered online that day's fasting blood glucose (FBG) level, the prior day's total daily insulin (TDI) dose, and whether the infusion set was changed.
Results: Mean duration of infusion set use was 3.0 days. Mean FBG level was higher with each successive day of infusion set use, increasing from 126 mg/dL on Day 1 to 133 mg/dL on Day 3 to 147 mg/dL on Day 5 (P<0.001). TDI dose did not vary with increased duration of infusion set use.
Conclusions: Internet-based data collection was used to rapidly conduct the study at low cost. The results indicate that FBG levels increase with each additional day of insulin pump infusion set use.
Source: PubMed