Gender, Success, and Drop-Out during a Resistance Exercise Program in Community Dwelling Old Adults

O G Geirsdottir, M Chang, K Briem, P V Jonsson, I Thorsdottir, A Ramel, O G Geirsdottir, M Chang, K Briem, P V Jonsson, I Thorsdottir, A Ramel

Abstract

Background: Resistance exercise training can be effective against sarcopenia. We identified predictors of drop-out and compared physical outcomes between men and women after such training.

Methods: Subjects (N = 236, 73.7 ± 5.7 years) participated in a 12-week resistance exercise program. Outcome variables were measured at baseline and endpoint.

Results: Drop-out was 11.9% and not significantly different between genders. Drop-outs were significantly older and had poorer strength and physical function in comparison to completers. Anthropometrics, QoL, and cognitive function were not related to drop-out. According to multivariate analysis, gait speed and physical activity were the strongest predictors of drop-out. After the training, gains in lean mass or appendicular muscle were significantly higher in men than women; however relative gains in appendicular muscle as well as absolute improvements in strength and function were similar in men and women, respectively.

Conclusions: Participants who drop out are older, have poorer physical function, and are less physically active. Old women do not drop out more frequently than men and show meaningful improvements in relevant outcomes similar to men after such a training program. The trial is registered at the US National Library of Medicine (NCT01074879).

Figures

Figure 1
Figure 1
Associations between age categories and risk of drop-out (chi-square statistics, P < 0.001).
Figure 2
Figure 2
Associations between gait speed categories and risk of drop-out (chi-square statistics, P = 0.065 for men and 0.008 for women; P < 0.001 for men and women combined).

References

    1. Dhillon R. J., Hasni S. Pathogenesis and management of sarcopenia. Clinics in Geriatric Medicine. 2017;33(1):17–26. doi: 10.1016/j.cger.2016.08.002.
    1. Csapo R., Alegre L. M. Effects of resistance training with moderate vs heavy loads on muscle mass and strength in the elderly: a meta-analysis. Scandinavian Journal of Medicine and Science in Sports. 2016;26(9):995–1006. doi: 10.1111/sms.12536.
    1. Arnarson A., Gudny Geirsdottir O., Ramel A., Briem K., Jonsson P. V., Thorsdottir I. Effects of whey proteins and carbohydrates on the efficacy of resistance training in elderly people: Double blind, randomised controlled trial. European Journal of Clinical Nutrition. 2013;67(8):821–826. doi: 10.1038/ejcn.2013.40.
    1. Ericsson A., Bremell T., Cider Å., Mannerkorpi K. Effects of exercise on fatigue and physical capacity in men with chronic widespread pain - a pilot study. BMC Sports Science, Medicine and Rehabilitation. 2016;8(1) doi: 10.1186/s13102-016-0054-9.
    1. Almadana Pacheco V., Pavón Masa M., Gómez-Bastero Fernández A. P., Muñiz Rodríguez A. M., Tallón Moreno R., Montemayor Rubio T. Patient profile of drop-outs from a pulmonary rehabilitation program. Archivos de Bronconeumologia. 2016 doi: 10.1016/j.arbres.2016.06.010.
    1. Zech A., Drey M., Freiberger E., et al. Residual effects of muscle strength and muscle power training and detraining on physical function in community-dwelling prefrail older adults: a randomized controlled trial. BMC Geriatrics. 2012;12, article 68 doi: 10.1186/1471-2318-12-68.
    1. Arikawa A. Y., O'Dougherty M., Schmitz K. H. Adherence to a strength training intervention in adult women. Journal of Physical Activity and Health. 2011;8(1):111–118. doi: 10.1123/jpah.8.1.111.
    1. U.S. Centers for Disease Control and Prevention and The Merck Company Foundation. Whitehouse Station, NJ: Merck Company Foundation; 2007. [Accessed Sep 2; 2008 ]. The state of aging and health in America 2007.
    1. Vezina J. W., Der Ananian C. A., Greenberg E., Kurka J. Sociodemographic correlates of meeting US department of health and human services muscle strengthening recommendations in middle-aged and older adults. Preventing Chronic Disease. 2014;11(9, article E162) doi: 10.5888/pcd11.140007.
    1. Da Boit M., Sibson R., Meakin J. R., et al. Sex differences in the response to resistance exercise training in older people. Physiological Reports. 2016;4(12, article e12834) doi: 10.14814/phy2.12834.
    1. Geirsdottir O. G., Arnarson A., Briem K., et al. Physical function predicts improvement in quality of life in elderly icelanders after 12 weeks of resistance exercise. Journal of Nutrition, Health and Aging. 2012;16(1):62–66. doi: 10.1007/s12603-011-0076-7.
    1. Arnarson A., Ramel A., Geirsdottir O. G., Jonsson P. V., Thorsdottir I. Changes in body composition and use of blood cholesterol lowering drugs predict changes in blood lipids during 12 weeks of resistance exercise training in old adults. Aging Clinical and Experimental Research. 2014;26(3):287–292. doi: 10.1007/s40520-013-0172-0.
    1. Ramel A., Geirsdottir O. G., Jonsson P. V., Thorsdottiri I. C-reactive protein and resistance exercise in community dwelling old adults. Journal of Nutrition, Health and Aging. 2015;19(7):792–796. doi: 10.1007/s12603-015-0548-2.
    1. Folstein M. F., Folstein S. E., McHugh P. R. “Mini mental state”. A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research. 1975;12(3):189–198. doi: 10.1016/0022-3956(75)90026-6.
    1. Geirsdottir O. G., Arnarson A., Briem K., Ramel A., Jonsson P. V., Thorsdottir I. Effect of 12-week resistance exercise program on body composition, muscle strength, physical function, and glucose metabolism in healthy, insulin-resistant, and diabetic elderly icelanders. Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2012;67(11):1259–1265. doi: 10.1093/gerona/gls096.
    1. Crapo R. O., Casaburi R., Coates A. L., et al. ATS statement: guidelines for the six-minute walk test. American Journal of Respiratory and Critical Care Medicine. 2002;166(1):111–117. doi: 10.1164/ajrccm.166.1.at1102.
    1. Troosters T., Gosselink R., Decramer M. Six minute walking distance in healthy elderly subjects. European Respiratory Journal. 1999;14(2):270–274. doi: 10.1034/j.1399-3003.1999.14b06.x.
    1. Enright P. L., Sherrill D. L. Reference equations for the six-minute walk in healthy adults. The American Journal of Respiratory and Critical Care Medicine. 1998;158(5, part 1):1384–1387. doi: 10.1164/ajrccm.158.5.9710086.
    1. Gibbons W. J., Fruchter N., Sloan S., Levy R. D. Reference values for a multiple repetition 6-minute walk test in healthy adults older than 20 years. Journal of Cardiopulmonary Rehabilitation. 2001;21(2):87–93. doi: 10.1097/00008483-200103000-00005.
    1. Podsiadlo D., Richardson S. The timed “Up and Go”: a test of basic functional mobility for frail elderly persons. Journal of the American Geriatrics Society. 1991;39(2):142–148. doi: 10.1111/j.1532-5415.1991.tb01616.x.
    1. Martínez-González M. A., Varo J. J., Santos J. L., et al. Prevalence of physical activity during leisure time in the European Union. Medicine and Science in Sports and Exercise. 2001;33(7):1142–1146. doi: 10.1097/00005768-200107000-00011.
    1. Ainsworth B. E., Haskell W. L., Whitt M. C., et al. Compendium of physical activities: an update of activity codes and MET intensities. Medicine and Science in Sports and Exercise. 2000;32(9):S498–S504. doi: 10.1097/00005768-200009001-00009.
    1. Paffenbarger R. S., Jr., Wing A. L., Hyde R. T. Physical activity as an index of heart attack risk in college alumni. American Journal of Epidemiology. 1978;108(3):161–175. doi: 10.1093/oxfordjournals.aje.a112608.
    1. Helgason T., Bjornsson J. K., Tomasson K., Ingimarsson S. Health related quality of life. Laeknabladid. 1997;83:492–502.
    1. Helgason T., Bjornsson J. K., Tomasson K., Gretarsdottir E. Health-related quality of life among Icelanders. Laeknabladid. 2000;86:251–257.
    1. ACSM. American College of Sports Medicine Position Stand. Progression models in resistance training for healthy adults. Medicine & Science in Sports & Exercise. 2009;41(3):687–708. doi: 10.1249/MSS.0b013e3181915670.
    1. Schoenfeld B. J. Is there a minimum intensity threshold for resistance training-induced hypertrophic adaptations? Sports Medicine. 2013;43(12):1279–1288. doi: 10.1007/s40279-013-0088-z.
    1. Schuenke M. D., Herman J., Staron R. S. Preponderance of evidence proves "big" weights optimize hypertrophic and strength adaptations. European Journal of Applied Physiology. 2013;113(1):269–271. doi: 10.1007/s00421-012-2528-0.
    1. Alegre L. M., Aguado X., Rojas-Martín D., Martín-García M., Ara I., Csapo R. Load-controlled moderate and high-intensity resistance training programs provoke similar strength gains in young women. Muscle and Nerve. 2015;51(1):92–101. doi: 10.1002/mus.24271.
    1. Geirsdottir O. G., Arnarson A., Ramel A., Thorsdottir I., Briem K., Jonsson P. V. Muscular strength and physical function in elderly adults 6–18 months after a 12-week resistance exercise program. Scandinavian Journal of Public Health. 2015;43(1):76–82. doi: 10.1177/1403494814560842.
    1. Kraemer W. J., Ratamess N. A. Hormonal responses and adaptations to resistance exercise and training. Sports Medicine. 2005;35(4):339–361. doi: 10.2165/00007256-200535040-00004.
    1. Kraemer W. J., Fleck S. J., Dziados J. E., et al. Changes in hormonal concentrations after different heavy-resistance exercise protocols in women. Journal of Applied Physiology. 1993;75(2):594–604.
    1. Kraemer W. J., Gordon S. E., Fleck S. J., et al. Endogenous anabolic hormonal and growth factor responses to heavy resistance exercise in males and females. International Journal of Sports Medicine. 1991;12(2):228–235. doi: 10.1055/s-2007-1024673.
    1. Schoenfeld B. J. The mechanisms of muscle hypertrophy and their application to resistance training. Journal of Strength & Conditioning Research. 2010;24(10):2857–2872. doi: 10.1519/jsc.0b013e3181e840f3.
    1. Bohannon R. W. Reference values for the timed up and go test: a descriptive meta-analysis. Journal of Geriatric Physical Therapy. 2006;29(2):64–68. doi: 10.1519/00139143-200608000-00004.
    1. Casanova C., Celli B. R., Barria P., et al. The 6-min walk distance in healthy subjects: reference standards from seven countries. European Respiratory Journal. 2011;37(1):150–156. doi: 10.1183/09031936.00194909.
    1. Gabriel D. A., Kamen G., Frost G. Neural adaptations to resistive exercise: mechanisms and recommendations for training practices. Sports Medicine. 2006;36(2):133–149. doi: 10.2165/00007256-200636020-00004.
    1. Adams J., White M. Are activity promotion interventions based on the transtheoretical model effective? A critical review. British Journal of Sports Medicine. 2003;37(2):106–114. doi: 10.1136/bjsm.37.2.106.
    1. Van Der Bij A. K., Laurant M. G. H., Wensing M. Effectiveness of physical activity interventions for older adults: a review. American Journal of Preventive Medicine. 2002;22(2):120–133. doi: 10.1016/S0749-3797(01)00413-5.

Source: PubMed

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