Effectiveness of physical therapy interventions for children with cerebral palsy: a systematic review

Heidi Anttila, Ilona Autti-Rämö, Jutta Suoranta, Marjukka Mäkelä, Antti Malmivaara, Heidi Anttila, Ilona Autti-Rämö, Jutta Suoranta, Marjukka Mäkelä, Antti Malmivaara

Abstract

Background: To assess the effectiveness of physical therapy (PT) interventions on functioning in children with cerebral palsy (CP).

Methods: A search was made in Medline, Cinahl, PEDro and the Cochrane library for the period 1990 to February 2007. Only randomized controlled trials (RCTs) on PT interventions in children with diagnosed CP were included. Two reviewers independently assessed the methodological quality and extracted the data. The outcomes measured in the trials were classified using the International Classification of Functioning, Disability and Health (ICF).

Results: Twenty-two trials were identified. Eight intervention categories were distinguished. Four trials were of high methodological quality. Moderate evidence of effectiveness was established for two intervention categories: effectiveness of upper extremity treatments on attained goals and active supination, and of prehensile hand treatment and neurodevelopmental therapy (NDT) or NDT twice a week on developmental status, and of constraint-induced therapy on amount and quality of hand use. Moderate evidence of ineffectiveness was found of strength training on walking speed and stride length. Conflicting evidence was found for strength training on gross motor function. For the other intervention categories the evidence was limited due to low methodological quality and the statistically insignificant results of the studies.

Conclusion: Due to limitations in methodological quality and variations in population, interventions and outcomes, mostly limited evidence on the effectiveness of most PT interventions is available through RCTs. Moderate evidence was found for some effectiveness of upper extremity training. Well-designed trials are needed especially for focused PT interventions.

Figures

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Figure 1
Article selection flow.

References

    1. Rosenbaum P, Paneth N, Leviton A, Goldstein M, Bax M. A report: the definition and classification of cerebral palsy April 2006. Dev Med Child Neurol. 2006;49:8–14.
    1. Bax M, Goldstein M, Rosenbaum P, Leviton A, Paneth N, Jacobsson B, Damiano DL. Proposed definition and classification of cerebral palsy, April 2005. Dev Med Child Neurol. 2005;47:571–576. doi: 10.1017/S001216220500112X.
    1. Odding E, Roebroeck M, Stam H. The epidemiology of cerebral palsy: incidence, impairments and risk factors. Disabil Rehabil. 2006;28:183–191. doi: 10.1080/09638280500158422.
    1. Scrutton D, Damiano DL, Mayston M. Management of the motor disorders of children with cerebral palsy. 2nd. Cambridge, Cambridge University Press; 2004. p. 191.
    1. World Confederation for Physical Therapy Description of Physical Therapy. Declarations of principle and position statements. 14th General Meeting of WCPT.
    1. The Bobath Approach. The Bobath Centre.
    1. Brown GT, Burns SA. The efficacy of neurodevelopmental treatments in children: a systematic review. Br J Occup Ther. 2001;64:235–244.
    1. Butler C, Darrah J. AACPDM Evidence report: Effects of neurodevelopmental treatment (NDT) for cerebral palsy. Dev Med Child Neurol. 2001;43:778–790. doi: 10.1017/S0012162201001414.
    1. Tirosh E, Rabino S. Physiotherapy for children with cerebral palsy. Evidence for its efficacy. Am J Dis Child. 1989;143:552–555.
    1. Dodd KJ, Taylor NF, Damiano DL. A systematic review of the effectiveness of strength training programs for people with cerebral palsy. Arch Phys Med Rehabil. 2002;83:1157–1164. doi: 10.1053/apmr.2002.34286.
    1. Darrah J, Fan JS, Chen LC, Nunweiler J, Watkins B. Review of the effects of progressive resisted muscle strengthening in children with cerebral palsy: a clinical consensus exercise. Pediatr Phys Ther. 1997;9:12–17. doi: 10.1097/00001577-199700910-00003.
    1. Darrah J, Watkins B, Chen L, Bonin C. Effects of conductive education intervention for children with cerebral palsy. AACPDM Evidence Report. pp. 1–34.
    1. Pedersen AV. Conductive education - a critical appraisal. Adv Physiother. 2000;2:75–82. doi: 10.1080/140381900443337.
    1. Ludwig S, Leggett P, Harstall C. Conductive education for children with cerebral palsy. Edmonton, Alberta Heritage Foundation for Medical Research (AHFMR). HTA 22; 2000. p. 54.
    1. French L, Nommensen A. Conductive education evaluated: future directions. Aust Occup Ther J. 1992;39:17–24.
    1. Boyd RN, Morris ME, Graham HK. Management of upper limb dysfunction in children with cerebral palsy: a systematic review. Eur J Neurol. 2001;8:150–166. doi: 10.1046/j.1468-1331.2001.00048.x.
    1. Hur JJ. Review of research on therapeutic interventions for children with cerebral palsy. Acta Neurol Scand. 1995;91:423–432.
    1. Parette HPJ, Hendricks MD, Rock SL. Efficacy of therapeutic intervention intensity with infants and young children with cerebral palsy. Infants Young Child. 1991;4:1–19.
    1. Horn EM. Basic motor skills instruction for children with neuromotor delays: a critical review. J Spec Educ. 1991;25:168–197.
    1. Morris C. A review of the efficacy of lower-limb orthoses used for cerebral palsy. Dev Med Child Neurol. 2002;44:205–211. doi: 10.1017/S0012162201001943.
    1. Teplicky R, Law M, Russell D. The effectiveness of casts, orthoses, and splints for children with neurological disorders. Infants Young Child. 2002;15:42–50.
    1. Hoare BJ, Wasiak J, Imms C, Carey L. Constraint-induced movement therapy in the treatment of the upper limb in children with hemiplegic cerebral palsy. Cochrane Database Syst Rev. 2007 Art No: CD004149.
    1. Harris SR, Roxborough L. Efficacy and effectiveness of physical therapy in enhancing postural control in children with cerebral palsy. Neural Plast. 2005;12:229–43; discussion 263-72. doi: 10.1155/NP.2005.229.
    1. Pin T, Dyke P, Chan M. The effectiveness of passive stretching in children with cerebral palsy. Dev Med Child Neurol. 2006;48:855–862. doi: 10.1017/S0012162206001836.
    1. Getz M, Hutzler Y, Vermeer A. Effects of aquatic interventions in children with neuromotor impairments: a systematic review of the literature. Clin Rehabil. 2006;20:927–936. doi: 10.1177/0269215506070693.
    1. Snider L, Korner-Bitensky N, Kammann C, Warner S, Saleh M. Horseback riding as therapy for children with cerebral palsy: is there evidence of its effectiveness? Phys Occup Ther Pediatr. 2007;27:5–23.
    1. Sterba JA. Does horseback riding therapy or therapist-directed hippotherapy rehabilitate children with cerebral palsy? Dev Med Child Neurol. 2007;49:68–73.
    1. Autti-Rämö I, Suoranta J, Anttila H, Malmivaara A, Mäkelä M. An Overview of Review Articles on the Effectiveness of Upper and Lower Limb Casting and Orthoses Used in Children with Cerebral Palsy. Am J Phys Med Rehabil. 2006;85:89–103. doi: 10.1097/01.phm.0000179442.59847.27.
    1. Siebes RC, Wijnroks L, Vermeer A. Qualitative analysis of therapeutic motor intervention programmes for children with cerebral palsy: an update. Dev Med Child Neurol. 2002;44:593–603. doi: 10.1017/S0012162201002638.
    1. Kunz R, Autti-Rämö I, Anttila H, Malmivaara A, Mäkelä M. A systematic review finds that methodological quality is better than its reputation but can be improved in physiotherapy trials in childhood cerebral palsy. J Clin Epidemiol. 2006;59:1239–1248. doi: 10.1016/j.jclinepi.2006.03.009.
    1. Physiotherapy Evidence Database PEDro
    1. World Health Organisation . ICF International classification of functioning, disability and health. Geneva, Switzerland, World Health Organisation; 2001.
    1. van Tulder M, Furlan A, Bombardier C, Bouter LM, the Editorial Board of the Cochrane Collaboration Back Review Group Updated method guidelines for systematic reviews in the Cochrane Collaboration Back Review Group. Spine. 2003;28:1290–1299. doi: 10.1097/00007632-200306150-00014.
    1. Bar-Haim S, Harries N, Belokopytov M, Frank A, Copeliovitch L, Kaplanski J, Lahat E. Comparison of efficacy of Adeli suit and neurodevelopmental treatments in children with cerebral palsy. Dev Med Child Neurol. 2006;48:325–330. doi: 10.1017/S0012162206000727.
    1. Tsorlakis N, Evaggelinou C, Grouios G, Tsorbatzoudis C. Effect of intensive neurodevelopmental treatment in gross motor function of children with cerebral palsy. Dev Med Child Neurol. 2004;46:740–745. doi: 10.1017/S0012162204001276.
    1. Ketelaar M, Vermeer A, Hart H, van Petegem-van Beek E, Helders PJ. Effects of a functional therapy program on motor abilities of children with cerebral palsy. Phys Ther. 2001;81:1534–1545.
    1. Bower E, Michell D, Burnett M, Campbell MJ, McLellan DL. Randomized controlled trial of physiotherapy in 56 children with cerebral palsy followed for 18 months. Dev Med Child Neurol. 2001;43:4–15. doi: 10.1017/S0012162201000020.
    1. Bower E, McLellan DL, Arney J, Campbell MJ. A randomised controlled trial of different intensities of physiotherapy and different goal-setting procedures in 44 children with cerebral palsy. Dev Med Child Neurol. 1996;38:226–237.
    1. Palmer FB, Shapiro BK, Allen MC, Mosher BS, Bilker SA, Harryman SE, Meinert CL, Capute AJ. Infant stimulation curriculum for infants with cerebral palsy: effects on infant temperament, parent-infant interaction, and home environment. Pediatrics. 1990;85:411–415.
    1. Wallen M, O'Flaherty SJ, Waugh MC. Functional outcomes of intramuscular botulinum toxin type a and occupational therapy in the upper limbs of children with cerebral palsy: a randomized controlled trial. Arch Phys Med Rehabil. 2007;88:1–10. doi: 10.1016/j.apmr.2006.10.017.
    1. Law M, Russell D, Pollock N, Rosenbaum P, Walter S, King G. A comparison of intensive neurodevelopmental therapy plus casting and a regular occupational therapy program for children with cerebral palsy. Dev Med Child Neurol. 1997;39:664–670.
    1. Law M, Cadman D, Rosenbaum P, Walter S, Russell D, DeMatteo C. Neurodevelopmental therapy and upper-extremity inhibitive casting for children with cerebral palsy. Dev Med Child Neurol. 1991;33:379–387.
    1. Hallam PM. The impact of prehension and fine motor development on gross motor activity in children with cerebral palsy. Liverpool, University of Liverpool; 1996. p. 444.
    1. Liao HF, Liu YC, Liu WY, Lin YT. Effectiveness of loaded sit-to-stand resistance exercise for children with mild spastic diplegia: a randomized clinical trial. Arch Phys Med Rehabil. 2007;88:25–31. doi: 10.1016/j.apmr.2006.10.006.
    1. Patikas D, Wolf SI, Mund K, Armbrust P, Schuster W, Doderlein L. Effects of a postoperative strength-training program on the walking ability of children with cerebral palsy: a randomized controlled trial. Arch Phys Med Rehabil. 2006;87:619–626. doi: 10.1016/j.apmr.2006.01.023.
    1. Patikas D, Wolf SI, Armbrust P, Mund K, Schuster W, Dreher T, Doderlein L. Effects of a postoperative resistive exercise program on the knee extension and flexion torque in children with cerebral palsy: a randomized clinical trial. Arch Phys Med Rehabil. 2006;87:1161–1169. doi: 10.1016/j.apmr.2006.05.014.
    1. Unger M, Faure M, Frieg A. Strength training in adolescent learners with cerebral palsy: a randomized controlled trial. Clin Rehabil. 2006:469–477. doi: 10.1191/0269215506cr961oa.
    1. Dodd KJ, Taylor NF, Graham HK. A randomized clinical trial of strength training in young people with cerebral palsy. Dev Med Child Neurol. 2003;45:652–657. doi: 10.1017/S0012162203001221.
    1. Dodd KJ, Taylor NF, Graham HK. Strength training can have unexpected effects on the self-concept of children with cerebral palsy. Pediatr Phys Ther. 2004;16:99–105. doi: 10.1097/01.PEP.0000127566.90996.50.
    1. Chad KE, Bailey DA, McKay HA, Zello GA, Snyder RE. The effect of a weight-bearing physical activity program on bone mineral content and estimated volumetric density in children with spastic cerebral palsy. J Pediatr. 1999;135:115–117. doi: 10.1016/S0022-3476(99)70340-9.
    1. van den Berg-Emons RJ, van Baak MA, Speth L, Saris WH. Physical training of school children with spastic cerebral palsy: effects on daily activity, fat mass and fitness. Int J Rehabil Res. 1998;21:179–194. doi: 10.1097/00004356-199806000-00006.
    1. Charles JR, Wolf SL, Schneider JA, Gordon AM. Efficacy of a child-friendly form of constraint-induced movement therapy in hemiplegic cerebral palsy: a randomized control trial. Dev Med Child Neurol. 2006;48:635–642. doi: 10.1017/S0012162206001356.
    1. Taub E, Ramey SL, DeLuca S, Echols K. Efficacy of constraint-induced movement therapy for children with cerebral palsy with asymmetric motor impairment. Pediatrics. 2004;113:305–312. doi: 10.1542/peds.113.2.305.
    1. Bumin G, Kayihan H. Effectiveness of two different sensory-integration programmes for children with spastic diplegic cerebral palsy. Disabil Rehabil. 2001;23:394–399. doi: 10.1080/09638280010008843.
    1. Ledebt A, Becher J, Kapper J, Rozendaal RM, Bakker R, Leenders IC, Savelsbergh GJP. Balance training with visual feedback in children with hemiplegic cerebral palsy: effect on stance and gait. Motor Control. 2005;9:459–468.
    1. Benda W, McGibbon NH, Grant KL. Improvements in muscle symmetry in children with cerebral palsy after equine-assisted therapy (hippotherapy) J Altern Complement Med. 2003;9:817–825. doi: 10.1089/107555303771952163.
    1. MacKinnon J, Noh S, Lariviere J, MacPhail A, Allan DE, Laliberte D. A study of therapeutic effects of horseback riding for children with cerebral palsy. Phys Occup Ther Pediatr. 1995;15:17–34. doi: 10.1300/J006v15n01_02.
    1. Palmer FB, Shapiro BK, Wachtel RC, Allen MC, Hiller JE, Harryman SE, Mosher BS, Meinert CL, Capute AJ. The effects of physical therapy on cerebral palsy. A controlled trial in infants with spastic diplegia. NEJM. 1988;318:803–808.
    1. Anttila H, Malmivaara A, Kunz R, Autti-Rämö I, Mäkelä M. Quality of reporting of randomized, controlled trials in cerebral palsy. Pediatrics. 2006;117:2222–2230. doi: 10.1542/peds.2005-1630.
    1. Kirshner B, Guyatt GH. A methodological framework for assessing health indices. J Chronic Dis. 1985;38:27–36. doi: 10.1016/0021-9681(85)90005-0.
    1. Vos-Vromans DC, Ketelaar M, Gorter JW. Responsiveness of evaluative measures for children with cerebral palsy: the Gross Motor Function Measure and the Pediatric Evaluation of Disability Inventory. Disabil Rehabil. 2005;27:1245–1252. doi: 10.1080/09638280500076178.
    1. Ketelaar M, Vermeer A, Helders PJM. Functional motor abilities of children with cerebral palsy: a systematic literature review of assessment measures. Clin Rehabil. 1998;12:369–380. doi: 10.1191/026921598673571117.

Source: PubMed

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