Community-level spillover effects of an intervention to prevent intimate partner violence and HIV transmission in rural Ethiopia

Jessica Leight, Negussie Deyessa, Fabio Verani, Samuel Tewolde, Vandana Sharma, Jessica Leight, Negussie Deyessa, Fabio Verani, Samuel Tewolde, Vandana Sharma

Abstract

Background: Intimate partner violence (IPV) is associated with adverse health and psychosocial outcomes. We analysed the spillover effects of Unite for a Better Life (UBL), an intervention evaluated in a cluster randomised controlled trial using a double-randomised design; previous evidence suggests UBL reduced IPV in rural Ethiopia among direct beneficiaries.

Methods: Villages (n=64) were randomly allocated to control, or to receive UBL delivered to men, women or couples. Each cluster comprised 106 surveyed households, including 21 randomly selected indirect beneficiary households who were not included in the intervention. Primary and secondary IPV outcomes included women's experience and men's perpetration of past-year physical or sexual IPV 24 months postintervention. An intention-to-treat analysis was conducted comparing indirect beneficiaries to sampled households in control communities. The analysis includes 2516 households surveyed at baseline in 2014-2015 (1680 households in the control arm, 258 indirect beneficiary households in the couples' arm, 287 indirect beneficiary households in the women's arm and 291 indirect beneficiary households in the men's arm). Follow-up data were available from 88% of baseline respondents and 86% of baseline spouses surveyed in 2017-2018, a total of 4379 individuals.

Results: Among indirect beneficiaries, there was no statistically significant intervention effect on women's past-year experience of physical or sexual IPV, while men's UBL significantly reduced reported perpetration of past-year sexual IPV (Adjusted Odds Ratio: 0.55; 95% CI 0.38 to 0.80, p=0.002). The intervention effects among indirect beneficiaries were statistically similar to those reported for the direct beneficiaries. In general, the hypothesis of equal effects cannot be rejected.

Conclusion: A gender-transformative intervention delivered to men was effective in reducing reported IPV even among indirect beneficiaries, suggesting that the programme had positive spillover effects in diffusing information and changing behaviours within the broader community.

Trial registration numbers: NCT02311699 and American Economic Association Registry (AEARCTR-0000211).

Keywords: HIV; disease; disorder; or injury; other infection; public health; randomised control trial.

Conflict of interest statement

Competing interests: VS, FV, ST, ND all received funding for either salary or consulting fees through a grant from an anonymous donor.

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Figures

Figure 1
Figure 1
Participant flow diagram.

References

    1. Devries KM, Mak JY, Bacchus LJ, et al. . Intimate partner violence and incident depressive symptoms and suicide attempts: a systematic review of longitudinal studies. PLoS Med 2013;10:e1001439. 10.1371/journal.pmed.1001439
    1. Ellsberg M, Jansen HAFM, Heise L, et al. . Intimate partner violence and women’s physical and mental health in the WHO multi-country study on women’s health and domestic violence: an observational study. The Lancet 2008;371:1165–72. 10.1016/S0140-6736(08)60522-X
    1. Garcia-Moreno C, Jansen HAFM, Ellsberg M, et al. . Prevalence of intimate partner violence: findings from the WHO multi-country study on women’s health and domestic violence. The Lancet 2006;368:1260–9. 10.1016/S0140-6736(06)69523-8
    1. Campbell JC. Health consequences of intimate partner violence. Lancet 2002;359:1331–6. 10.1016/S0140-6736(02)08336-8
    1. Hill A, Pallitto C, McCleary-Sills J, et al. . A systematic review and meta-analysis of intimate partner violence during pregnancy and selected birth outcomes. Int J Gynaecol Obstet 2016;133:269–76. 10.1016/j.ijgo.2015.10.023
    1. Pronyk PM, Hargreaves JR, Kim JC, et al. . Effect of a structural intervention for the prevention of intimate-partner violence and HIV in rural South Africa: a cluster randomised trial. Lancet 2006;368:1973–83. 10.1016/S0140-6736(06)69744-4
    1. Jewkes R, Nduna M, Levin J, et al. . Impact of stepping stones on incidence of HIV and HSV-2 and sexual behaviour in rural South Africa: cluster randomised controlled trial. BMJ 2008;337:391–5. 10.1136/bmj.a506
    1. Saggurti N, Nair S, Silverman JG, et al. . Impact of the RHANI wives intervention on marital conflict and sexual coercion. Int J Gynaecol Obstet 2014;126:18–22. 10.1016/j.ijgo.2014.01.015
    1. Kapiga S, Harvey S, Mshana G, et al. . A social empowerment intervention to prevent intimate partner violence against women in a microfinance scheme in Tanzania: findings from the MAISHA cluster randomised controlled trial. Lancet Glob Health 2019;7:e1423–34. 10.1016/S2214-109X(19)30316-X
    1. Hossain M, Zimmerman C, Kiss L, et al. . Working with men to prevent intimate partner violence in a conflict-affected setting: a pilot cluster randomized controlled trial in rural Côte d’Ivoire. BMC Public Health 2014;14 10.1186/1471-2458-14-339
    1. Vaillant J, Koussoubé E, Roth D, et al. . Engaging men to transform inequitable gender attitudes and prevent intimate partner violence: a cluster randomised controlled trial in North and South Kivu, Democratic Republic of Congo. BMJ Glob Health 2020;5:e002223. 10.1136/bmjgh-2019-002223
    1. Doyle K, Levtov RG, Barker G, et al. . Gender-transformative Bandebereho couples' intervention to promote male engagement in reproductive and maternal health and violence prevention in Rwanda: findings from a randomized controlled trial. PLoS One 2018;13:e0192756. 10.1371/journal.pone.0192756
    1. Gupta J, Falb KL, Lehmann H, et al. . Gender norms and economic empowerment intervention to reduce intimate partner violence against women in rural Côte d'Ivoire: a randomized controlled pilot study. BMC Int Health Hum Rights 2013;13:46. 10.1186/1472-698X-13-46
    1. Dunkle K, Erin E, Heise L. Impact of Indashyikirwa. An innovative programme to reduce partner violence in rural Rwanda [Internet], 2019. Available:
    1. Abramsky T, Devries K, Kiss L, et al. . Findings from the Sasa! study: a cluster randomized controlled trial to assess the impact of a community mobilization intervention to prevent violence against women and reduce HIV risk in Kampala, Uganda. BMC Med 2014;12:122. 10.1186/s12916-014-0122-5
    1. Ogum Alangea D, Addo-Lartey AA, Chirwa ED, et al. . Evaluation of the rural response system intervention to prevent violence against women: findings from a community-randomised controlled trial in the central region of Ghana. Glob Health Action 2020;13:1711336. 10.1080/16549716.2019.1711336
    1. Chatterji S, Stern E, Dunkle K, et al. . Community activism as a strategy to reduce intimate partner violence (IPV) in rural Rwanda: results of a community randomised trial. J Glob Health 2020;10:010406. 10.7189/jogh.10.010406
    1. Wagman JA, Gray RH, Campbell JC, et al. . Effectiveness of an integrated intimate partner violence and HIV prevention intervention in Rakai, Uganda: analysis of an intervention in an existing cluster randomised cohort. Lancet Glob Health 2015;3:e23–33. 10.1016/S2214-109X(14)70344-4
    1. Bradley JE, Bhattacharjee P, Ramesh BM, et al. . Evaluation of stepping stones as a tool for changing knowledge, attitudes and behaviours associated with gender, relationships and HIV risk in Karnataka, India. BMC Public Health 2011;11:496. 10.1186/1471-2458-11-496
    1. Benjamin-Chung J, Abedin J, Berger D, et al. . Spillover effects on health outcomes in low- and middle-income countries: a systematic review. Int J Epidemiol 2017;46:1251–76. 10.1093/ije/dyx039
    1. Benjamin-Chung J, Amin N, Ercumen A, et al. . A randomized controlled trial to measure spillover effects of a combined water, sanitation, and handwashing intervention in rural Bangladesh. Am J Epidemiol 2018;187:1733–44. 10.1093/aje/kwy046
    1. Sharma V, Leight J, Verani F, et al. . Effectiveness of a culturally appropriate intervention to prevent intimate partner violence and HIV transmission among men, women, and couples in rural Ethiopia: findings from a cluster-randomized controlled trial. PLoS Med 2020;17:e1003274. 10.1371/journal.pmed.1003274
    1. Leight J, Deyessa N, Verani F, et al. . An intimate partner violence prevention intervention for men, women, and couples in Ethiopia: additional findings on substance use and depressive symptoms from a cluster-randomized controlled trial. PLoS Med 2020;17:e1003131. 10.1371/journal.pmed.1003131
    1. Benjamin-Chung J, Arnold BF, Berger D, et al. . Spillover effects in epidemiology: parameters, study designs and methodological considerations. Int J Epidemiol 2018;47:332–47. 10.1093/ije/dyx201
    1. Liang K-YEE, Zeger SL. Longitudinal data analysis using generalized linear models. Biometrika 1986;73:13–22. 10.1093/biomet/73.1.13
    1. Starmann E, Heise L, Kyegombe N, et al. . Examining diffusion to understand the how of Sasa!, a violence against women and HIV prevention intervention in Uganda. BMC Public Health 2018;18:616. 10.1186/s12889-018-5508-4
    1. Clemens J, Shin S, Ali M. New approaches to the assessment of vaccine herd protection in clinical trials. Lancet Infect Dis 2011;11:482–7. 10.1016/S1473-3099(10)70318-2
    1. Cislaghi B, Denny EK, Cissé M, et al. . Changing Social Norms: the Importance of "Organized Diffusion" for Scaling Up Community Health Promotion and Women Empowerment Interventions. Prev Sci 2019;20:936–46. 10.1007/s11121-019-00998-3
    1. Chong A, Gonzalez-Navarro M, Karlan D, et al. . Do Information Technologies Improve Teenagers’ Sexual Education? Evidence from a Randomized Evaluation in Colombia. World Bank Econ Rev 2020;34:371–92. 10.1093/wber/lhy031
    1. Dupas P. Do teenagers respond to HIV risk information? Evidence from a field experiment in Kenya. American Economic Journal: Applied Economics 2011;3:1–34. 10.1257/app.3.1.1
    1. Jaffe J, Kaler A. Coffee ceremonies, gender, and food security in two Ethiopian villages : Njuki J, Parkins J, Kaler A, Transforming gender and food security in the global South. New York City: Routledge, 2016: 115–37.
    1. Crittenden KS, Kaponda CPN, Jere DL, et al. . Participation and diffusion effects of a peer-intervention for HIV prevention among adults in rural Malawi. Soc Sci Med 2015;133:136–44. 10.1016/j.socscimed.2015.03.055
    1. Moher D, Hopewell S, Schulz KF, et al. . Consort 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. Int J Surg 2012;10:28–55. 10.1016/j.ijsu.2011.10.001
    1. Rothman KJ. No adjustments are needed for multiple comparisons. Epidemiology 1990;1:43–6. 10.1097/00001648-199001000-00010

Source: PubMed

3
Prenumerera