Acupuncture against the metabolic risk factors for stroke: A systematic review of systematic reviews

Ying Xu, Da-Yuan Zhong, Xiao-Qian Liao, Xing-Ping Wang, Jin-Wen Ge, Wei-Hui Xu, Ying Xu, Da-Yuan Zhong, Xiao-Qian Liao, Xing-Ping Wang, Jin-Wen Ge, Wei-Hui Xu

Abstract

Objective: This systematic review (SR) of SRs aims aimed to evaluate the current evidence of rehabilitation interventions in stroke patients after acupuncture treatment.

Methods: Full-text SRs published in Chinese and English up to December 15, 2021 were searched in PubMed, Embase, Cochrane Library, CNKI, VIP, and Wanfang databases. The PRISMA statement and the assessment of multiple systematic reviews 2 (AMSTAR 2) scale were used to evaluate the quality of the included articles. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system was employed to assess the outcome indicators for evidence quality evaluation.

Results: A number of 42 publications were identified in this study. According to these articles, 4 metabolic areas were identified: systolic blood pressure, weight loss, glycemic index and cholesterol. The acupuncture is beneficial to improve the systolic blood pressure of patients, and the effect of acupuncture on diastolic blood pressure is better than that of sham acupuncture. The weight loss effect of acupuncture is better than that of lifestyle and western medicine. The improvement effect of acupuncture on body mass index (BMI) is also better than that of sham acupuncture. In the study of glycemic index of stroke patients, acupuncture significantly improved glycosylated hemoglobin and insulin sensitivity index compared with western medicine. In cholesterol-related research, acupuncture can effectively improve the content of triglycerides. However, studies on HDL and LDL show that acupuncture can significantly improve HDL, but has no significant effect on LDL.

Conclusion: This review summarizes the available evidence and underpins findings of the acupuncture exhibited the therapeutic role in eliminating metabolic risk factors for stroke, including systolic blood pressure, weight loss, glycemic index and cholesterol. Acupuncture could have positive effects on a specific symptom, and the effects depend not only on intervention type but also on how and when the intervention is provided. And more prioritizing high-quality research in this field in the future is conducive to guiding clinical practice.

Conflict of interest statement

The authors have no conflicts of interest to disclose.

Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

Figures

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Figure 1.
Identification: A total of 1240 documents were identified by systematically checked (777 literatures from Chinese databases, 463 literatures from English databases) each database Until December 15, 2021, search for relevant eligible randomized controlled trials with keywords or Mesh terms “acupuncture,” “body acupuncture,” “electroacupuncture,” “hypertension,” etc. In total, 887 articles left after removing duplicates. 2. Screening and extraction: By carefully reading the titles and abstracts of the literature, and according to the inclusion and exclusion criteria, the related literature was screened to determine whether it would be included in subsequent studies. If there is a dispute or a divergent issue, it will be resolved through internal consultation or discussion with a third party. A total of 139 articles were selected. 3. Included Full-text articles were assessed for eligibility, studies included in qualitative synthesis(systematic reviews) were 42.

References

    1. Christopher J, Murray L. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the global burden of disease study 2019. Lancet. 2014;396:1204–22.
    1. GBD 2016 Stroke Collaborators. Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the global burden of disease study 2016. Lancet. 2019;18:439–58.
    1. Feigin VL, Nguyen G, Cercy K, et al. ; GBD 2016 Lifetime Risk of Stroke Collaborators. Global, regional, and Country-Specific lifetime risks of stroke, 1990 and 2016. N Engl J Med. 2018;379:2429–37.
    1. Bruce CVC, Khatri P. Stroke. Lancet. 2020;396:129–42.
    1. Wang XP, Gao CY, Li MW, et al. . Expert consensus on assessment, detection and intervention of common risk factors for cardiovascular and cerebrovascular diseases. ChinJ Appl Diagnosis Treat. 2021;35:541–51.
    1. Ford ES, Ajani UA, Croft JB, et al. . Explaining the decrease in us deaths from coronary disease, 1980-2000. Surv Anesthesiol. 2007;51:326.
    1. Xia Y, Ding GH, Wu GC. Current research in acupuncture. Springer. 2013:559–99.
    1. Tao H, Yang LT, Ping A, et al. . Quality evaluation tool AMSTAR 2 for systematic reviews of random or non-random control research Interpretation. Chin J Evid Based Med. 2018;18:101–8.
    1. Chen YL, Yao L, Susan N, et al. . The necessity and precautions of GRADE in systematic review. Chin J Evid Based Med. 2013;13:1401–4.
    1. Lee H, Kim SY, Park J, et al. . Acupuncture for lowering blood pressure: systematic review and meta-analysis.. Am J Hypertens. 2009;22:122–8.
    1. Chen C, Liu J, Sun MX, et al. . Acupuncture for type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. Complement Ther Clin Pract. 2019;36:100–12.
    1. Chen H, Shen FE, Tan XD, et al. . Efficacy and safety of acupuncture for essential hypertension: a meta-analysis. Med scie monit. 2018;24:2946–69.
    1. Cho SH, Lee JS, Thabane L, et al. . Acupuncture for obesity: a systematic review and meta-analysis. Int J Obes. 2019;33:183–96.
    1. Li DZ, Zhou Y, Yang YN, et al. . Acupuncture for essential hypertension: a meta-analysis of randomized sham-controlled clinical trials. Evid Based Complement Alternat Med. 2014;2014:279478.
    1. Yao JP, He ZQ, Chen Y, et al. . Acupuncture and weight loss in Asians: a PRISMA-compliant systematic review and meta-analysis. Medicine. 2019;98:e16815.
    1. Zhang KP, Zhou SG, Wang CY, et al. . Acupuncture on obesity: clinical evidence and possible neuroendocrine mechanisms. Evid Based Complement Alternat Med. 2018;2018:6409389.
    1. Zhang RQ, Tan J, Li FY, et al. . Acupuncture for the treatment of obesity in adults: a systematic review and meta-analysis.. Postgrad Med J. 2017;93: 743–751.
    1. Tan X, Pan Y, Su W, et al. . Acupuncture therapy for essential hypertension: a network meta-analysis. Ann Transl Med. 2019;7:266.
    1. Wang J, Xiong X, Liu W, et al. . Acupuncture for essential hypertension. Int J Cardiol. 2013;169:317–26.
    1. Wu L, Chen X, Liu Y, et al. . Role of acupuncture in the treatment of insulin resistance: a systematic review and meta-analysis. Complement Ther Clin Pract. 2019;37:11–22.
    1. Phillips J. Acupuncture for hypertension. Res Nurs Health. 2020;43:294–5.
    1. Zhao XF, Hu HT, Li JS, et al. . Is acupuncture effective for hypertension? a systematic review and meta-analysis. PLoS One. 2015;10:e0127019.
    1. Zhong YM, Luo XC, Chen Y, et al. . Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis. Postgrad Med J. 2020;96:221–7.
    1. Chang XR. Evidence-based study on acupuncture and moxibustion for hyperlipidemia. Chin Assoc Acupunct Moxibustion. 2014:8–13.
    1. Chen H. Construction of evidence system of acupuncture and moxibustion for essential hypertension based on reticular analysis. Nanjing Univ Chin Med. 2019.
    1. Chen X, Huang W, Deng J, et al. . A meta analysis of the effect of acupuncture at renying point on essential hypertension. J Clin Acupunct Moxibustion. 2016;32:64–9.
    1. Liu N, Fan XN, Meng ZH, et al. . A meta analysis of the effect of acupuncture at renying point on essential hypertensio. Henan Tradit Chin Med. 2017;37:1282–7.
    1. Li DP, Kong LH, Qin R, et al. . Meta analysis of clinical effect of acupuncture and moxibustion on simple obesity. J Hubei Univ Tradit Chin Med. 2014;16:100–2.
    1. Li XH. Systematic evaluation of li xiaohan’s abdominal acupuncture therapy for simple obesity. Chengdu Univ TCM. 2015.
    1. Lin XM, Li B, Du YH, et al. . Systematic evaluation of clinical effect of acupuncture on simple obesity. Chin Acupuncture Moxibustion. 2009;29:856–60.
    1. Liu ML, Zhang GS, Li CW, et al. . Systematic evaluation of randomized controlled clinical trial of acupuncture and moxibustion for hyperlipidemia. Liaoning J Tradit Chin Med. 2015;42:2065–70.
    1. Chen YY, Zhai JB, Shi T, et al. . Clinical effect meta analysis of acupuncture at renying point for primary hypertension. New Tradit Chin Med. 2017;49:184–8.
    1. Ma CY. Meta of acupuncture and moxibustion therapy for hypertension based on randomized controlled trials. Shandong Tradit Chin Med Univ. 2016.
    1. Ma ZQ, Ge M. A meta-analysis of the safety and efficacy of acupuncture in treating hyperlipidemia. Henan province Traditl Chin Med. 2012;32:1398–401.
    1. Qian YX. Systematic evaluation of efficacy and safety of acupuncture in the treatment of essential hypertension. Northern Pharm. 2013;10:72–4.
    1. Shi LW, Li Q, Li XW, et al. . Systemic evaluation of acupuncture intervention in prediabetes. Shandong J Tradit Chin Med. 2018;37:282–8.
    1. Tang HZ. Systematic evaluation of acupuncture and moxibustion for essential hypertension. Chengdu Univ TCM. 2011.
    1. Wang F, Pei J. Meta analysis of the effect of acupuncture on blood pressure variability regulation. Chin Insti Acupuncture Moxibustion. 2019:1046–52.
    1. Xia YY. A systematic evaluation of acupuncture obesity. Chengdu Univ TCM. 2015.
    1. Xiao GC. A meta analysis of the effect of acupuncture and moxibustion on essential hypertension. Guiyang Coll Tradit Chin Med. 2015.
    1. Xing CG, Sun Z, Ma YC, et al. . Meta analysis of the effect of acupuncture on islet function in type 2 diabetic patientset al. J Nanjing Univ Chin Med. 2015;31:397–400.
    1. Yang LF, Huang LJ, Li Y, et al. . Clinical effect of abdominal acupuncture on simple obesity meta analysis. Clin Study Tradit Chin Med. 2015;7:1–4.
    1. Yu H, Tan J, Han QJ, et al. . Effect of acupuncture on essential hypertension. Clin J Acupunct Moxibustion. 2013;29:39–45.
    1. Yu Z, Ju CH, Xu B, et al. . Evaluation of clinical randomized controlled trial of acupuncture for simple obesity. Shi Zhen Ntl Med. 2010;21:434–6.
    1. Zhang JP. Effect of acupuncture on fcmri brain function connection of taixi point in patients with essential hypertension. Southern Med Univ. 2017.
    1. Zhang L, Zeng XT, Tian GX, et al. . A meta analysis of the effect of acupuncture and antihypertensive drugs on essential hypertension. Chin J Evid Based Cardiovasc Med. 2017;9:1420–6.
    1. Zhang L, Zeng XT, Tian GX, et al. . Effect of acupuncture on essential hypertension and analysis of acupoint frequency. Liaoning J Tradit Chin Med. 2013;40:2115–9.
    1. Zhu T, Ding L. Meta analysis of acupuncture at fengchi and quchi acupoints in the treatment of essential hypertension. Clin J Tradit Chin Med. 2018;30:461–5.
    1. Zhang YJ, Shu ZJ, Gao Y, et al. . Meta analysis of the effect of acupuncture and acupuncture on mild and moderate essential hypertension. Liaoning J Tradit Chin Med. 2014;41:1802–6.
    1. Zhao R, Fu LX, Xiong J, et al. . Systematic evaluation of the long-term effect of acupuncture on essential hypertension. Clin J Acupunct Moxibustion. 2011;27:46–51.
    1. Shan ZL, Song AQ, Qian SY, et al. . Meta analysis of clinical effect of electroacupuncture on simple obesity. Diet care. 2019;6:95–6.
    1. ogata J, Yamanishi H, Ishibashi-ueda H, et al. . Review: role of cerebral vessels in ischaemic injury of the brain. Neuropathol Appl Neurobiol. 2011;37:40–55.
    1. Puja G, Nirmal S, Arunachalam M, et al. . Pharmacologic evidence for role of endothelial nitric oxide synthase in neuroprotective mechanism of ischemic postconditioning in mice. J Surg Res. 2014;188:349–60.
    1. Peng JP. Study on the clinical efficacy and safety of cerebral angiography in acute ischemic cerebrovascular disease. World’s Latest Med Info Digest. 2017;17:12 + 14.
    1. Wang L. Clinical study of arterial thrombolysis combined with interventional therapy for senile patients with acute cerebrovascular occlusion.Modern diagnosis and treatment. 2017;28:1872–3.
    1. Hu J, Pang WS, Han J, et al. . Gualou Guizhi decoction reverses brain damage with cerebral ischemic stroke, multi-component directed multi-target to screen calcium-overload inhibitors using combination of molecular docking and protein–protein docking.. J Enzyme Inhib Med Chem. 2018;33:115–25.
    1. Kim KA, Shin D, Kim JH, et al. . Role of autophagy in endothelial damage and blood-brain barrier disruption in ischemic stroke. Stroke. 2018;49:1571–9.
    1. Wilhelm I, Nyúl-tóth A, Kozma M, et al. . Role of pattern recognition receptors of the neurovascular unit in inflamm-aging. AJP Heart Circ Physiol. 2017;313:H1000–12.

Source: PubMed

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