Pulmonary infection and colonization with nontuberculous mycobacteria, Taiwan, 2000-2012

Jung-Yien Chien, Chih-Cheng Lai, Wang-Huei Sheng, Chong-Jen Yu, Po-Ren Hsueh, Jung-Yien Chien, Chih-Cheng Lai, Wang-Huei Sheng, Chong-Jen Yu, Po-Ren Hsueh

Abstract

We analyzed samples from 13,652 patients who had respiratory cultures positive for mycobacteria in Taiwan during 2000-2012 and found that 56.9% were positive for nontuberculous mycobacteria (NTM). Whereas annual prevalence of tuberculosis decreased during the study period, prevalence of NTM disease and colonization increased, particularly among older patients and male patients.

Keywords: MTB; Mycobacterium tuberculosis; NTM; Taiwan; bacteria; colonization; infection; isolation; nontuberculous mycobacteria; prevalence; pulmonary; respiratory infections; tuberculosis and other mycobacteria.

Figures

Figure 1
Figure 1
Annual incidence of tuberculosis, pulmonary nontuberculous mycobacteria (NTM) infection, and NTM colonization among patients registered in the National Taiwan University Hospital Mycobacterial Laboratory database with cultures positive for Mycobacterium tuberculosis or NTM, 2000–2012.
Figure 2
Figure 2
Rates of Mycobacterium tuberculosis infection, nontuberculous mycobacteria (NTM) infection, and NTM colonization/contamination, by age (A) and sex (B), among patients registered in the National Taiwan University Hospital Mycobacterial Laboratory database with cultures positive for Mycobacterium tuberculosis or NTM, 2000–2012. *p<0.01 compared with first group.

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Source: PubMed

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