Nanomaterials for Wound Healing and Infection Control

Mara Madalina Mihai, Monica Beatrice Dima, Bogdan Dima, Alina Maria Holban, Mara Madalina Mihai, Monica Beatrice Dima, Bogdan Dima, Alina Maria Holban

Abstract

Wound healing has been intensely studied in order to develop an "ideal" technique that achieves expeditious recovery and reduces scarring to the minimum, thus ensuring function preservation. The classic approach to wound management is represented by topical treatments, such as antibacterial or colloidal agents, in order to prevent infection and promote a proper wound-healing process. Nanotechnology studies submicroscopic particles (maximum diameter of 100 nm), as well as correlated phenomena. Metal nanoparticles (e.g., silver, gold, zinc) are increasingly being used in dermatology, due to their beneficial effect on accelerating wound healing, as well as treating and preventing bacterial infections. Other benefits include: ease of use, less frequent dressing changes and a constantly moist wound environment. This review highlights recent findings regarding nanoparticle application in wound management.

Keywords: chronic infection; infections control; nano-dressings; nanoparticles; wound healing.

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Correlation between the clinical outlook, microbiological and host-related factors in acute and chronic wounds.
Figure 2
Figure 2
Main types of nanomaterials which can be used for wound treatment.

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