Global critical care: a call to action

Ana Maria Crawford, Ananya Abate Shiferaw, Papytcho Ntambwe, Alexei Ortiz Milan, Karima Khalid, Rodrigo Rubio, Francoise Nizeyimana, Fredy Ariza, Alhassan Datti Mohammed, Tim Baker, Paulin Ruhato Banguti, Farai Madzimbamuto, Ana Maria Crawford, Ananya Abate Shiferaw, Papytcho Ntambwe, Alexei Ortiz Milan, Karima Khalid, Rodrigo Rubio, Francoise Nizeyimana, Fredy Ariza, Alhassan Datti Mohammed, Tim Baker, Paulin Ruhato Banguti, Farai Madzimbamuto

Abstract

Critical care is underprioritized. A global call to action is needed to increase equitable access to care and the quality of care provided to critically ill patients. Current challenges to effective critical care in resource-constrained settings are many. Estimates of the burden of critical illness are extrapolated from common etiologies, but the true burden remains ill-defined. Measuring the burden of critical illness is epidemiologically challenging but is thought to be increasing. Resources, infrastructure, and training are inadequate. Millions die unnecessarily due to critical illness. Solutions start with the implementation of first-step, patient care fundamentals known as Essential Emergency and Critical Care. Such essential care stands to decrease critical-illness mortality, augment pandemic preparedness, decrease postoperative mortality, and decrease the need for advanced level care. The entire healthcare workforce must be trained in these fundamentals. Additionally, physician and nurse specialists trained in critical care are needed and must be retained as leaders of critical care initiatives, researchers, and teachers. Context-specific research is mandatory to ensure care is appropriate for the patient populations served, not just duplicated from high-resourced settings. Governments must increase healthcare spending and invest in capacity to treat critically ill patients. Advocacy at all levels is needed to achieve universal health coverage for critically ill patients.

Keywords: Burden of illness; Critical care; Critical illness; Global health; ICU.

Conflict of interest statement

TB, AMC, and KK are founders, actively involved, or directors of working groups for the EECC Network.

© 2023. The Author(s).

Figures

Fig. 1
Fig. 1
Global critical care: a call to action
Fig. 2
Fig. 2
EECC is cross-cutting, improving access and quality of critical care at low cost and complexity. Adapted from Schell, C.O., Gerdin Wärnberg, M., Hvarfner, A. et al. The global need for essential emergency and critical care. Crit Care 22, 284 (2018)

References

    1. Meara JG, Greenberg SLM. The Lancet Commission on Global Surgery Global surgery 2030: evidence and solutions for achieving health, welfare and economic development. Surgery. 2015;157(5):834–835. doi: 10.1016/j.surg.2015.02.009.
    1. Vincent JL. The continuum of critical care. Crit Care. 2019;23(S1):122. doi: 10.1186/s13054-019-2393-x.
    1. Ortiz-Ospina E, Roser M, Ritchie H. Life expectancy.
    1. Institute for Health Metrics and Evaluation, Global Burden of Disease (2019). Burden of Disease, 2019. Our world in data.
    1. Hirshon JM, Risko N, Calvello EJ, et al. Health systems and services: the role of acute care. Bull World Health Organ. 2013;91(5):386–388. doi: 10.2471/BLT.12.112664.
    1. Kayambankadzanja RK, Schell CO, Gerdin Wärnberg M, et al. Towards definitions of critical illness and critical care using concept analysis. BMJ Open. 2022;12(9):e060972. doi: 10.1136/bmjopen-2022-060972.
    1. Schell CO, Gerdin Wärnberg M, Hvarfner A, et al. The global need for essential emergency and critical care. Crit Care. 2018;22(1):284. doi: 10.1186/s13054-018-2219-2.
    1. Murthy S, Wunsch H. Clinical review: international comparisons in critical care—lessons learned. Crit Care. 2012;16(2):218. doi: 10.1186/cc11140.
    1. Biccard BM, Madiba TE, Kluyts HL, et al. Perioperative patient outcomes in the African Surgical Outcomes Study: a 7-day prospective observational cohort study. The Lancet. 2018;391(10130):1589–1598. doi: 10.1016/S0140-6736(18)30001-1.
    1. World Health Organization. The top 10 causes of death. Published December 9, 2020. . Accessed 25 June 2021.
    1. Rudd KE, Johnson SC, Agesa KM, et al. Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study. The Lancet. 2020;395(10219):200–211. doi: 10.1016/S0140-6736(19)32989-7.
    1. Riviello ED, Kiviri W, Twagirumugabe T, et al. Hospital incidence and outcomes of the acute respiratory distress syndrome using the Kigali modification of the Berlin definition. Am J Respir Crit Care Med. 2016;193(1):52–59. doi: 10.1164/rccm.201503-0584OC.
    1. Bellani G, Laffey JG, Pham T, et al. Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA. 2016;315(8):788. doi: 10.1001/jama.2016.0291.
    1. Knaul FM, Bhadelia A, Rodriguez NM, Arreola-Ornelas H, Zimmermann C. The Lancet Commission on Palliative Care and Pain Relief—findings, recommendations, and future directions. Lancet Glob Health. 2018;6:S5–S6. doi: 10.1016/S2214-109X(18)30082-2.
    1. Murdoch DR, Howie SRC. The global burden of lower respiratory infections: making progress, but we need to do better. Lancet Infect Dis. 2018;18(11):1162–1163. doi: 10.1016/S1473-3099(18)30407-9.
    1. Lin X, Xu Y, Pan X, et al. Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025. Sci Rep. 2020;10(1):14790. doi: 10.1038/s41598-020-71908-9.
    1. World Health Organization. Cardiovascular diseases. Published June 11, 2021.
    1. Kruk ME, Gage AD, Arsenault C, et al. High-quality health systems in the sustainable development goals era: time for a revolution. Lancet Glob Health. 2018;6(11):e1196–e1252. doi: 10.1016/S2214-109X(18)30386-3.
    1. Madzimbamuto FD. Ventilators are not the answer in Africa. Afr J Prim Health Care Fam Med. 2020 doi: 10.4102/phcfm.v12i1.2517.
    1. Lettieri CJ, Shah AA, Greenburg DL. An intensivist-directed intensive care unit improves clinical outcomes in a combat zone. Crit Care Med. 2009;37(4):1256–1260. doi: 10.1097/CCM.0b013e31819c167f.
    1. Multz AS, Chalfin DB, Samson IM, et al. A “closed” medical intensive care unit (MICU) improves resource utilization when compared with an “open” MICU. Am J Respir Crit Care Med. 1998;157(5):1468–1473. doi: 10.1164/ajrccm.157.5.9708039.
    1. Dimick JB, Pronovost PJ, Heitmiller RF, Lipsett PA. Intensive care unit physician staffing is associated with decreased length of stay, hospital cost, and complications after esophageal resection. Crit Care Med. 2001;29(4):753–758. doi: 10.1097/00003246-200104000-00012.
    1. Moss M, Good VS, Gozal D, Kleinpell R, Sessler CN. A critical care societies collaborative statement: burnout syndrome in critical care health-care professionals. A call for action. Am J Respir Crit Care Med. 2016;194(1):106–113. doi: 10.1164/rccm.201604-0708ST.
    1. Maitland K, Kiguli S, Opoka RO, et al. Mortality after fluid bolus in African children with severe infection. N Engl J Med. 2011;364(26):2483–2495. doi: 10.1056/NEJMoa1101549.
    1. Silberberg B, Aston S, Boztepe S, Jacob S, Rylance J. Recommendations for fluid management of adults with sepsis in sub-Saharan Africa: a systematic review of guidelines. Crit Care. 2020;24(1):286. doi: 10.1186/s13054-020-02978-4.
    1. Andrews B, Semler MW, Muchemwa L, et al. Effect of an early resuscitation protocol on in-hospital mortality among adults with sepsis and hypotension: a randomized clinical trial. JAMA. 2017;318(13):1233. doi: 10.1001/jama.2017.10913.
    1. World Health Organization. Global spending on health 2020: weathering the storm. World Health Organization; 2020. . Accessed 20 Sept 2022
    1. World Health Organization. Global expenditure on health: public spending on the rise? World Health Organization; 2021. . Accessed 20 Sept 2022
    1. Roosa T, Melinda KA. U.S. Health Care from a Global Perspective, 2019: higher spending, worse outcomes? The commonwealth fund: improving health care quality. Published January 30, 2020.
    1. Manda-Taylor L, Mndolo S, Baker T. Critical care in Malawi: the ethics of beneficence and justice. Malawi Med J. 2017;29(3):268. doi: 10.4314/mmj.v29i3.8.
    1. Sen-Crowe B, Sutherland M, McKenney M, Elkbuli A. A closer look into global hospital beds capacity and resource shortages during the COVID-19 pandemic. J Surg Res. 2021;260:56–63. doi: 10.1016/j.jss.2020.11.062.
    1. Ssewante N, Wekha G, Namusoke M, et al. Assessment of knowledge, attitude and practice of first aid among taxi operators in a Kampala City Taxi Park, Uganda: a cross-sectional study. Afr J Emerg Med. 2022;12(1):61–66. doi: 10.1016/j.afjem.2021.10.007.

Source: PubMed

3
Prenumerera