The Effectiveness of Low-Level Laser Therapy in Pain Induced by Orthodontic Separator Placement: A Systematic Review

Arash Farzan, Katayoon Khaleghi, Arash Farzan, Katayoon Khaleghi

Abstract

Introduction: This systematic review was conducted to evaluate the effectiveness of low-level laser therapy (LLLT) in orthodontic separator pain. Methods: This article was written according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist. Electronically and manually 3 databases, namely PubMed, Scopus and Google Scholar, were searched by the keywords that were selected based on population, intervention, comparison and outcome (PICO) on October 10, 2020. Studies were appraised by Cochrane version 5.2.0 with 7 domains and were checked by these inclusion criteria: 1. Randomized clinical trial (RCT) that examined the efficacy of LLLT in separator pain, 2. Split-mouth design, 3. LLLT application in the first hours after separator placement, 4. LLLT application to both sides of the teeth, 5. Patients receiving elastomeric separators between the premolars and molars, 6. Lasers with a wavelength of 800-899 nm, 7. Studies conducted from 2010 to 2020, and 8. Participants who went through orthodontic treatment without limitation in gender, age and social-economic status. Results: 299 studies were screened. 34 full-text papers were read by 2 authors independently. In the end, 4 articles met the inclusion criteria. All 4 articles showed LLLT has a significant impact on pain reduction. Conclusion: The exact protocol for laser therapy is still not clear. Therefore, more studies with a meticulously designed method are needed.

Keywords: Elastomeric separator; Low-level light therapy; Pain.

Copyright © 2021 J Lasers Med Sci.

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References

    1. Ren C, McGrath C, Yang Y. The effectiveness of low-level diode laser therapy on orthodontic pain management: a systematic review and meta-analysis. Lasers Med Sci. 2015;30(7):1881–93. doi: 10.1007/s10103-015-1743-4.
    1. Martins IP, Martins RP, Caldas SGFR, dos Santos-Pinto A, Buschang PH, Pretel H. Low-level laser therapy (830 nm) on orthodontic pain: blinded randomized clinical trial. Lasers Med Sci. 2019;34(2):281–6. doi: 10.1007/s10103-018-2583-9.
    1. Ortega SM, Gonçalves MLL, Da Silva T, Horliana ACRT, Motta LJ, Altavista OM. et al. Evaluation of the use of photobiomodulation following the placement of elastomeric separators: Protocol for a randomized controlled clinical trial. Medicine (United States) 2019;98(43) doi: 10.1097/md.0000000000017325.
    1. Eslamian L, Dehghani F, Amraie H. Comparison of Ketoprofen Gum and Ketoprofen Gel for Pain Relief after Activation of Orthodontic Appliances. J Islam Dent Assoc Iran. 2016;28(4):142–8. doi: 10.30699/jidai.29.4.142.
    1. Eslamian L, Youssefinia S, Ameli N. Efficacy of Ketoprofen and Benzocaine Chewing Gums for Reducing Orthodontic Pain. J Islam Dent Assoc Iran. 2014;26(4):218–24.
    1. Patel D, Mubeen S, Taylor N. Separators: a review of uses and limitations. Ortho Update. 2018;11(2):61–6. doi: 10.12968/ortu.2018.11.2.61.
    1. Almallah MM, Almahdi WH, Hajeer MY. Evaluation of low level laser therapy on pain perception following orthodontic elastomeric separation: a randomized controlled trial. J Clin Diagn Res. 2016;10(11):ZC23. doi: 10.7860/jcdr/2016/22813.8804.
    1. Farias RD, Motta RH. Low-level laser therapy for controlling pain in orthodontic patients during the use of elastic separators: randomized clinical trial. Laser Phys Lett. 2018;15(9):095602. doi: 10.1088/1612-202x/aad1c1.
    1. Borzabadi-Farahani A, Cronshaw M. Lasers in orthodontics. Lasers in Dentistry—Current Concepts. Springer; 2017. p. 247-71. 10.1007/978-3-319-51944-9_12
    1. Eslamian L, Borzabadi-Farahani A, Hassanzadeh-Azhiri A, Badiee MR, Fekrazad R. The effect of 810-nm low-level laser therapy on pain caused by orthodontic elastomeric separators. Lasers Med Sci. 2014;29(2):559–64. doi: 10.1007/s10103-012-1258-1.
    1. Shi Q, Yang S, Jia F, Xu J. Does low level laser therapy relieve the pain caused by the placement of the orthodontic separators? a meta-analysis. Head Face Med. 2015;11(1):28. doi: 10.1186/s13005-015-0085-6.
    1. Almallah MME, Hajeer MY, Almahdi WH, Burhan AS, Latifeh Y, Madkhaneh SK. Assessment of a single versus double application of low-level laser therapy in pain reduction following orthodontic elastomeric separation: A randomized controlled trial. Dent Med Probl. 2020;57(1):45–52. doi: 10.17219/dmp/113332.
    1. Artés-Ribas M, Arnabat-Dominguez J, Puigdollers A. Analgesic effect of a low-level laser therapy (830 nm) in early orthodontic treatment. Lasers Med Sci. 2013;28(1):335–41. doi: 10.1007/s10103-012-1135-y.
    1. Qamruddin I, Alam MK, Fida MP, Khan AG. Effect of a single dose of low-level laser therapy on spontaneous and chewing pain caused by elastomeric separators. Am J Orthod Dentofacial Orthop. 2016;149(1):62–6. doi: 10.1016/j.ajodo.2015.06.024.
    1. Abtahi SM, Mousavi SA, Shafaee H, Tanbakuchi B. Effect of low-level laser therapy on dental pain induced by separator force in orthodontic treatment. Dent Res J. 2013;10(5):647. doi: 10.4317/jced.51979.
    1. Ganesh G, Tripathi T, Rai P, Kanase A. Effect of photobiomodulation on pain perception secondary to separator placement. Laser Dent Sci. 2019;3(2):111–7. doi: 10.1007/s41547-019-00058-7.
    1. Arshad F, Dharmesh H, Bharathi V, Ram AA, Begum S. Effect of Two Energy Values of 810-nm Diode LLLT on Reducing Pain Caused by Orthodontic Elastomeric Separators: A Split Mouth Randomized Controlled Clinical Study. Int J Prev Clin Dent Res. 2018;5(2):1–4.
    1. AlSayed Hasan MMA, Sultan K, Hamadah O. Evaluating low-level laser therapy effect on reducing orthodontic pain using two laser energy values: a split-mouth randomized placebo-controlled trial. Eur J Orthod. 2018;40(1):23–8. doi: 10.1093/ejo/cjx013.
    1. Gupta S, Ahuja S, Bhambri E, Sharma S, Sharma R, Kalia H. Evaluating the effect of low-level laser therapy on pain induced by orthodontic separation: a randomized split-mouth clinical trial. Laser Dent Sci. 2018;2(4):221–8. doi: 10.1007/s41547-018-0040-5.
    1. Nóbrega C, da Silva EMK, de Macedo CR. Low-level laser therapy for treatment of pain associated with orthodontic elastomeric separator placement: a placebo-controlled randomized double-blind clinical trial. Photomed Laser Surg. 2013;31(1):10–6. doi: 10.1089/pho.2012.3338.
    1. Lim HM, Lew KKK, Tay DKL. A clinical investigation of the efficacy of low level laser therapy in reducing orthodontic postadjustment pain. Am J Orthod Dentofacial Orthop. 1995;108(6):614–22. doi: 10.1016/s0889-5406(95)70007-2.
    1. Fujiyama K, Deguchi T, Murakami T, Fujii A, Kushima K, Takano-Yamamoto T. Clinical effect of CO2 laser in reducing pain in orthodontics. Angle Orthod. 2008;78(2):299–303. doi: 10.2319/033007-153.1.
    1. Figueira IZ, Sousa APC, Machado AW, Habib FAL, Soares LGP, Pinheiro ALB. Clinical study on the efficacy of LED phototherapy for pain control in an orthodontic procedure. Lasers Med Sci. 2019;34(3):479–85. doi: 10.1007/s10103-018-2617-3.
    1. Oshagh M, Najafi HZ, Bahramnia F, Gharesi-Fard B. Comparison of the analgesic effect of Ibuprofen and pulsed low-level laser in reducing pain after orthodontic separator placement and evaluation of the changes in the sulcular pain especially prostaglandin E2 level. J Dent Lasers. 2014;8(2):44. doi: 10.4103/0976-2868.145137.
    1. Marini I, Bartolucci ML, Bortolotti F, Innocenti G, Gatto MR, Alessandri Bonetti G. The effect of diode superpulsed low-level laser therapy on experimental orthodontic pain caused by elastomeric separators: a randomized controlled clinical trial. Lasers Med Sci. 2015;30(1):35–41. doi: 10.1007/s10103-013-1345-y.
    1. Kim WT, Bayome M, Park J-B, Park JH, Baek S-H, Kook Y-A. Effect of frequent laser irradiation on orthodontic pain: a single-blind randomized clinical trial. Angle Orthod. 2013;83(4):611–6. doi: 10.2319/082012-665.1.
    1. Esper MÂLR, Nicolau RA, Arisawa EÂLS. The effect of two phototherapy protocols on pain control in orthodontic procedure-a preliminary clinical study. Lasers Med Sci. 2011;26(5):657–63. doi: 10.1007/s10103-011-0938-6.
    1. Buchwald B. Effects of Low Level Laser Therapy on Orthodontic Pain. Texas A&M University; 2014. 10.1007/978-3-540-29805-2_2223
    1. Furquim RD, Pascotto RC, Neto JR, Cardoso JR, Ramos AL. Low-level laser therapy effects on pain perception related to the use of orthodontic elastomeric separators. Dental Press J Orthod. 2015;20(3):37–42. doi: 10.1590/2176-9451.20.3.037-042.oar.
    1. Stein S, Korbmacher-Steiner H, Popovic N, Braun A. Pain reduced by low-level laser therapy during use of orthodontic separators in early mixed dentition. J Orofac Orthop. 2015;76(5):431–9. doi: 10.1007/s00056-015-0306-4.
    1. Higgins J, Green S. Cochrane handbook for systematic reviews. The cochrane collaboration; 2008. 10.1002/9780470712184
    1. Lesaffre E, Philstrom B, Needleman I, Worthington H. The design and analysis of split‐mouth studies: what statisticians and clinicians should know. Stat Med. 2009;28(28):3470–82. doi: 10.1002/sim.3634.
    1. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg. 2010;8(5):336–41. doi: 10.1016/j.ijsu.2010.02.007.
    1. Topolski F, Moro A, Correr GM, Schimim SC. Optimal management of orthodontic pain. J Pain Res. 2018;11:589. doi: 10.2147/jpr.s127945.

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