A novel transurethral resection technique for superficial bladder tumor: retrograde en bloc resection
Kai-Yan Zhang, Jin-Chun Xing, Wei Li, Zhun Wu, Bin Chen, Dong-Yu Bai, Kai-Yan Zhang, Jin-Chun Xing, Wei Li, Zhun Wu, Bin Chen, Dong-Yu Bai
Abstract
Background: Transurethral resection of bladder tumor (TURBT) is the standard approach to bladder tumors but suffers from several disadvantages. The aim of this study was to evaluate the safety and efficacy of a novel procedure of retrograde en bloc resection of bladder tumor (RERBT) with conventional monopolar resection electrode for the treatment of superficial bladder tumors.
Methods: RERBT and conventional TURBT (C-TURBT) were conducted, respectively, in 40 and 50 patients diagnosed with superficial papillary bladder tumors. In the RERBT group, the tumors were en bloc removed retrogradely under direct vision using a conventional monopolar electrode. Patients' clinicopathological, intraoperative, and postoperative data were compared retrospectively between the RERBT and C-TURBT groups.
Results: Of the 90 patients, 40 underwent RERBT and 50 underwent C-TURBT. Both groups were comparable in clinicopathological characteristic. RERBT could be performed as safely and effectively as C-TURBT. There were no significant differences in operative time and surgical complications. The cumulative recurrence rates between groups were similar during up to 18 months follow-up. The detrusor muscle could be identified pathologically in 100% of RERBT tumor specimens and the biopsy of tumor bases, but only in 54 and 70%, respectively, of C-TURBT samples (P < 0.01).
Conclusions: The RERBT technique is feasible and safe for superficial bladder tumors using conventional monopolar resection setting, with the advantages of adequate tumor resection and the ability to collect good quality tumor specimens for pathological diagnosis and staging compared to conventional TURBT.
Keywords: En-bloc resection; Non-muscle-invasive bladder cancer; Transurethral resection of bladder tumor.
Conflict of interest statement
Ethics approval and consent to participateThis study was approved by the Ethics Committee of Xiamen University Affiliated First Hospital.
Consent for publicationAll patients enrolled in the study signed the consent for publication.
Competing interestsThe authors declare that they have no competing interests.
Publisher’s NoteSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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