Predictors and outcome of surgical repair of obstetric fistula at a regional referral hospital, Mbarara, western Uganda

Musa Kayondo, Ssalongo Wasswa, Jerome Kabakyenga, Nozmo Mukiibi, Jude Senkungu, Amy Stenson, Peter Mukasa, Musa Kayondo, Ssalongo Wasswa, Jerome Kabakyenga, Nozmo Mukiibi, Jude Senkungu, Amy Stenson, Peter Mukasa

Abstract

Background: Obstetric fistula although virtually eliminated in high income countries, still remains a prevalent and debilitating condition in many parts of the developing world. It occurs in areas where access to care at childbirth is limited, or of poor quality and where few hospitals offer the necessary corrective surgery.

Methods: This was a prospective observational study where all women who attended Mbarara Regional Referral Hospital in western Uganda with obstetric fistula during the study period were assessed pre-operatively for social demographics, fistula characteristics, classification and outcomes after surgery. Assessment for fistula closure and stress incontinence after surgery was done using a dye test before discharge

Results: Of the 77 women who were recruited in this study, 60 (77.9%) had successful closure of their fistulae. Unsuccessful fistula closure was significantly associated with large fistula size (Odds Ratio 6 95% Confidential interval 1.46-24.63), circumferential fistulae (Odds ratio 9.33 95% Confidential interval 2.23-39.12) and moderate to severe vaginal scarring (Odds ratio 12.24 95% Confidential interval 1.52-98.30). Vaginal scarring was the only factor independently associated with unsuccessful fistula repair (Odds ratio 10 95% confidential interval 1.12-100.57). Residual stress incontinence after successful fistula closure was associated with type IIb fistulae (Odds ratio 5.56 95% Confidential interval 1.34-23.02), circumferential fistulae (Odds ratio 10.5 95% Confidential interval 1.39-79.13) and previous unsuccessful fistula repair (Odds ratio 4.8 95% Confidential interval 1.27-18.11). Independent predictors for residual stress incontinence after successful fistula closure were urethral involvement (Odds Ratio 4.024 95% Confidential interval 2.77-5.83) and previous unsuccessful fistula repair (Odds ratio 38.69 95% Confidential interval 2.13-703.88).

Conclusions: This study demonstrated that large fistula size, circumferential fistulae and marked vaginal scarring are predictors for unsuccessful fistula repair while predictors for residual stress incontinence after successful fistula closure were urethral involvement, circumferential fistulae and previous unsuccessful fistula repair.

Figures

Figure 1
Figure 1
Fistula types among study participants in relation to outcome of repair.

References

    1. WHO. The World Health Report 2005: Make Every Mother and Child count. Geneva, Switzerland: WHO; 2005.
    1. UNFPA. Campaign to end fistula. 2008. assessed March 2010.
    1. Arrowsmith E, Hamlin CE, Wall LL. Obstructed labour injury complex: Obstetric fistula formation and the multifaceted mobility of maternal birth trauma in the developing world. Obstet Gynecol Surv. 1996;51(9):568–74. doi: 10.1097/00006254-199609000-00024.
    1. Hancock B, Collie M. Vesicovaginal fistula surgery in Uganda. East and Central African Journal of surgery. 2004;2:95–99.
    1. Waaldijk K. Surgical classification of obstetric fistula. International Journal of gynaecology and obstetrics. 1995;49:161–3. doi: 10.1016/0020-7292(95)02350-L.
    1. Wall LL. Obstetric Vesicovaginal fistula as an International Public Health problem. The Lancet. 2006;368(9542):1201–1209. doi: 10.1016/S0140-6736(06)69476-2.
    1. Donnay F, Weil L. Obstetric fistula: the international response. The Lancet. 2004;363:71–2. doi: 10.1016/S0140-6736(03)15177-X.
    1. UNFPA and EngenderHealth. Obstetric Fistula Needs Assessment Report: findings from nine African countries. New York: UNFPA and Engender Health; 2003.
    1. Creanga AA, Ahmad S. Prevention and treatment of Obstetric fistula: Identifying research needs and public health priorities. International Journal of Gynaecology and Obstetrics. 2007;99(1):151–4.
    1. Muleta M. Socio-demographic Profile and Obstetric experience of fistula Patients managed at Addis Ababa fistula hospital. Ethiopia Medical Journal. 2004;42(1):9–16.
    1. Uganda Bureau of Statistics and Macro International Inc. Uganda Demographic and Health Survey 2005/2006. Calverton, Merryland, USA: UBOS and Macro International Inc; 2007.
    1. Ministry of Health, Uganda. Fistula Technical Working. 2003.
    1. Ministry of Health, Uganda. Roadmap for Accelerating the Reduction of Maternal and Neonatal Mortality and Morbidity in Uganda. 2007.
    1. Ministry of Health, Uganda. National Obstetric Fistula Strategy. 2011.
    1. UNFPA and Ministry of Health Uganda. Campaign to end fistula: Baseline Assessment of obstetric fistula in Uganda. New York: UNFPA; 2003.
    1. Kelly J. An epidemiological study of vesicovaginal fistula in Addis Ababa. World Health statistics quarterly Report. 1995;48(1):15–17.
    1. Kabir M, Iliyasu Z, Abubakar IS, Umer UI. Medico-social problems of patients with vesicovaginal fistula in Murtala Muhammed Specialist Hospital, Kano. Annals of African Medicine. 2003;2:54–57.
    1. Holme A, Breen M, MacArthur C. Obstetric fistula: a study of women managed at the Monze Mission Hospital, Zambia. BJOG. 2007;114:1010–7. doi: 10.1111/j.1471-0528.2007.01353.x.
    1. Nisar N, Yousfani S, Muntaz F. Profile of women who experienced vesicovaginal fistula due to obstetric trauma: results from a survey at a gynaecological surgical camp 2005. Pak J Med Sci. 2010;26(1):62–65.
    1. Johnson K. Incontinence in Malawi: Analysis of a proxy measure of vesicovaginal fistula in a national survey. International Journal of Gynaecology and Obstetrics. 2007;99:122–129. doi: 10.1016/j.ijgo.2007.04.044.
    1. Nathan LM, Rochat HC, Bank E, Gringorescu B. Obstetric fistula in West Africa: patients' perspectives. Am J Obstet Gynecol. 2008;200(5):40–42.
    1. Browning A, Menber B. Women with obstetric fistula in Ethiopia: a 6-month follow-up after surgical treatment. BJOG. 2008;115:1564–1569. doi: 10.1111/j.1471-0528.2008.01900.x.
    1. Muleta M. Obstetric fistula: a retrospective study of 1210 cases at the Addis Ababa Fistula Hospital. J Obstet Gynaecol. 1997;17:68–70. doi: 10.1080/01443619750114194.
    1. Gessessew A, Mesfin M. Genitourinary and rectovaginal fistulae in Adigaft Zonal Hospital, Tigray, northern Ethiopia. Ethiopia Med J. 2003;41:123–30.
    1. Browning A. Prevention of residual urinary incontinence following successful repair of obstetric vesicovaginal fistula using a fibromascular sling. BJOG. 2004;111:357–61. doi: 10.1111/j.1471-0528.2004.00080.x.
    1. Roenneburg M, Genadry R, Wheeles CJ. Repair of obstetric vesicovaginal fistulas in Africa. Am J Obstet Gynecol. 2006;195:1748–52. doi: 10.1016/j.ajog.2006.07.031.
    1. Goh TWJ, Browning A, Chang A. Predicting the risk of failure of closure of obstetric fistula and residual urinary incontinence using a classification system. Int Urogynecol J. 2008;19:1659–1662. doi: 10.1007/s00192-008-0693-9.
    1. Nardos R, Browning A, Chen CCG. Risk factors that predict failure after vaginal repair of obstetric vesicovaginal fistulae. Am J Obstet Gynecol. 2009;200:578.e1–578.e4. doi: 10.1016/j.ajog.2008.12.008.
    1. Browning A. Risk factors for developing residual urinary incontinence after obstetric fistula repair. BJOG. 2006;113:482–485. doi: 10.1111/j.1471-0528.2006.00875.x.
    1. Wall LL, Karshima JA, Arrowsmith SD. The obstetric Vesicovaginal fistula: characteristics of 899 patients from Jos, Nigeria. Am J Obstet Gynecol. 2004;190(4):1011–19. doi: 10.1016/j.ajog.2004.02.007.

Source: PubMed

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