Neonatal early-onset sepsis calculator recommended significantly less empiric antibiotic treatment than national guidelines
Bo M van der Weijden, Niek B Achten, Jolita Bekhof, Esther E Evers, Oviedo van Dongen, Maarten Rijpert, Arvid W A Kamps, Gavin W Ten Tusscher, Marlies A van Houten, Frans B Plötz, Bo M van der Weijden, Niek B Achten, Jolita Bekhof, Esther E Evers, Oviedo van Dongen, Maarten Rijpert, Arvid W A Kamps, Gavin W Ten Tusscher, Marlies A van Houten, Frans B Plötz
No abstract availableKeywords: antibiotic therapy; newborn; sepsis calculator.
Conflict of interest statement
None.
References
- van der Weijden BM, Achten NB, Bekhof J, et al. Dutch multicentre study found that adherence to antibiotic recommendations for neonatal early‐onset sepsis is low. Acta Paediatr. Submitted.
- Escobar GJ, Puopolo KM, Wi S, et al. Stratification of risk of early‐onset sepsis in newborns ≥ 34 weeks' gestation. Pediatrics. 2014;133:30‐36.
- Achten NB, Klingenberg C, Benitz WE, et al. Association of use of the neonatal early‐onset sepsis calculator with reduction in antibiotic therapy and safety. JAMA Pediatr. 2019;173:1032‐1040.
- Goel N, Shrestha S, Smith R, et al. Screening for early onset neonatal sepsis: NICE guidance‐based practice versus projected application of the Kaiser Permanente sepsis risk calculator in the UK population. Arch Dis Child – Fetal Neonatal Ed. 2020;105(2):118‐122.
- Achten NB, Visser DH, Tromp E, Groot W, van Goudoever JB, Plötz FB. Early onset sepsis calculator implementation is associated with reduced healthcare utilization and financial costs in late preterm and term newborns. Eur J Pediatr. 2020;179:727‐734.
Source: PubMed