Human amniotic membrane dressing for the treatment of an infected wound due to an entero-cutaneous fistula: Case report

Dimitri Barski, Holger Gerullis, Thorsten Ecke, Gabriella Varga, Mihaly Boros, Isabel Pintelon, Jean-Pierre Timmermans, Thomas Otto, Dimitri Barski, Holger Gerullis, Thorsten Ecke, Gabriella Varga, Mihaly Boros, Isabel Pintelon, Jean-Pierre Timmermans, Thomas Otto

Abstract

Introduction: Infected wounds are difficult to treat and there are no standardized protocols.

Presentation of case: We report a case of infected postoperative wound and entero-cutaneous fistula in a 83 years-old woman. An innovative treatment protocol for Human amniotic membrane (HAM)-assisted dressing of infected wound as the Idea Stage following the IDEAL recommendations is presented. The development of amnion preparation and the involved treatment steps are described. No adverse events and no graft rejection have been detected.

Discussion: Favorable results confirm the technical simplicity, safety and efficacy of this procedure. HAM has been shown to promote wound healing and to have antibacterial characteristics, which was supported by the presented case.

Conclusion: We are able to report a successful treatment of an infected wound caused by entero-cutaneous fistula with HAM dressing. Following the IDEAL recommendations, consecutive prospective cohort trials are justified.

Keywords: Amniotic membrane; Case report; Chronic wound; Dressing; IDEAL recommendations.

Copyright © 2018 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Figures

Fig. 1
Fig. 1
A. Initial presentation with entero-cutaneous fistula and wound ulceration. B. After 2 weeks the secretion stopped and the wound was reduced by 20% and contracted. HAM dressing is marked with an arrow.
Fig. 2
Fig. 2
Histological analysis of wound healing. High magnification (400×) Vimentin-stained sections. A. shows epidermis formation and dermis composition with muscle cell formation (arrows). B. shows muscle cells (arrows) adhering to the scattered pieces of HAM.

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