Endoscopic Findings in Patients With Typical Gastroesophageal Reflux Disease (GERD) Symptoms
Endoscopic Findings in Taiwan Patients Presenting With Characteristic Symptoms of Gastroesophageal Reflux Disease
研究概览
地位
条件
详细说明
This study amis to investigate upper endoscopic findings of typical acid reflux patients with and without alarm symptoms in Taiwan During the period from May 2008 to December 2009, consecutive adult outpatients, who receive upper endoscopy for characteristic reflux symptoms of heartburn or acid regurgitation, are invited to participate. All study participants are evaluated for presence of pre-defined alarm symptoms including odynophagia or dysphagia, gastrointestinal bleeding, involuntary body weight loss and anemia.
Upper endoscopic procedures are performed with standard electronic videoendoscope (GIF-Q240 or GIF-Q260; Olympus, Tokyo, Japan) by experienced endoscopists; each of them had previously performed a minimum of 2,000 upper endoscopy exams. Representative images are taken and stored as electronic files in a digital image system for later analysis.
The following five significant endoscopic findings are pre-defined endpoints of this study: 1) any malignant lesion in the upper digestive tract, 2) Barrett esophagus, 3) severe erosive esophagitis (LA grade C or D), 4) peptic stricture, 5) peptic ulcer.
研究类型
注册 (预期的)
联系人和位置
学习地点
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-
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Lotung Town, Ilan County、台湾、265
- Lotung Poh-Ai Hospital
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- outpatients
- chief complaints of characteristic GERD symptoms (heart burn or acid regurgitation), evaluated by standard questionnaire
- undergo upper digestive endoscopy
Exclusion Criteria:
- age less than 18 years old or more than 90 years old
- unable to complete upper endoscopy
- known diagnosis of gastroesophageal malignancy
- follow-up visit for known gastroesophageal lesion identified by previous upper endoscopy
- failure to obtain informed consent
学习计划
研究是如何设计的?
设计细节
- 观测模型:队列
- 时间观点:横截面
队列和干预
团体/队列 |
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1
Patients with pre-defined alarm symptoms
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2
Patients without pre-defined alarm symptoms
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研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
---|---|
Pre-defined significant upper digestive endoscopic findings
大体时间:within one month after the endoscopy examination
|
within one month after the endoscopy examination
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合作者和调查者
调查人员
- 首席研究员:Yao-Chun Hsu, M.D.、Lotung Poh-Ai Hospital
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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