Hiperemezis and Serotonin Elevated Serum Serotonin Levels in Hyperemesis
Relationship Between Elevated Serum Serotonin Levels in Symptomatic Patients With Hyperemezis
研究概览
详细说明
The occurrence of severe nausea and vomiting of early pregnancy (hiperemezis gravid arum) is estimated between 0.3% to 1% of all pregnancies. Although hiperemezis gravid arum has been recognized for a long time, its pathophysiologic mechanisms are still poorly understood. Many theories have been advocated, but to date none of these have been convincing.
It has been demonstrated that the nausea and vomiting associated with increased in serotonin liberation. This has provided a rationale for the treatment of these symptoms with specific serotonin antagonists.
The aim of this trial was to investigate the possible relationship between hiperemezis gravid arum and serotonin liberation.
研究类型
注册 (预期的)
联系人和位置
学习地点
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Istanbul、火鸡、34140
- 招聘中
- Bakirkoy Dr Sadi Konuk Training and Research Hospital
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- 6-14 week pregnant women
- nausea
- protracted vomiting
- inability to tolerate food intake accompanied by obvious dehydration
- severe enough to justify hospitalisation
- at least 2+ ketonuria on dipstick urinanalysis.
Exclusion Criteria:
- with metabolic disorders such as diabet, thyroid
学习计划
研究是如何设计的？
设计细节
研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
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serum serotonin levels in hiperemezis gravidarum
大体时间：6-14week pregnancy
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6-14week pregnancy
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次要结果测量
结果测量 |
大体时间 |
|---|---|
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ıs there any assosiation between serotonin levels and severity of symptoms in pregnant women with hiperemezis
大体时间：6-14week pregnancy
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6-14week pregnancy
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其他结果措施
结果测量 |
大体时间 |
|---|---|
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ıs there any assosiation between other serum parameters includes estrogen,progesterone and serum beta hcg
大体时间：6-14week pregnancy
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6-14week pregnancy
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合作者和调查者
调查人员
- 学习椅：hüseyin cengiz, md、Bakırkoy Dr. Sadi Konuk Training and Research Hospital
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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