Endoscopic Ultrasound in Detailed T-staging of Upper GI Malignancies in Vitro
研究概览
地位
条件
详细说明
- EUS Examination After the surgery, the specimen is filled with 0.9%NS (normal saline ) without cut open,and put into a container filled with 0.9%NS before fixation in formalin. EUS will be performed on the resected specimen.The endoscopy move from the distal to proximal side along the longitudinal axis of stomach, evaluate the invasion of gastric wall, and mark the deepest point with sutures under the EUS guided. The images were stored .
EUS images the are reviewed by two endoscopists. They are asked to stage the tumor according to the AJCC(American Joint Committee on Cancer) staging system (7th edition) , assign a level of confidence to the staging, and score the quality of the EUS image .
- Histologic Preparations and Examination Carcinoma invasion into each layer of the gastric wall is diagnosed by an experienced pathologist (L.ZW) who is unaware of the findings of the EUS imaging. The marked section will be assessed separately.
- Data analysis The diagnosis between the pathologic findings and EUS prediction will be compared. Whether the marked point was the deepest in pathologic findings is recorded. And the histological section and the EUS image of the marked point is compared.
研究类型
注册 (预期的)
联系人和位置
学习地点
-
-
Beijing
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Beijing、Beijing、中国、100142
- 招聘中
- Beijing Cancer Hospital
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接触:
- Yan Yan, Doctor
- 电话号码:861088196168
- 邮箱:dr.yan@outlook.com
-
首席研究员:
- Yan Yan, Doctor
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Patients with upper GI carcinoma
- Receive surgery as first treatment
Exclusion Criteria:
- previous surgery involved the upper GI tract
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
---|
early gastric cancer
EUS examination on the specimen right after surgery mark the deepest invasive site on the specimen
|
Locally Advanced Gastric Cancer
EUS examination on the specimen right after surgery mark the deepest invasive site on the specimen
|
early esophagus cancer
EUS examination on the specimen right after surgery mark the deepest invasive site on the specimen
|
locally advanced esophagus cancer
EUS examination on the specimen right after surgery mark the deepest invasive site on the specimen
|
研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
---|---|
the consistency between EUS and pathologic determination of tumor depth
大体时间:1 month (after careful examination by 2 pathologists)
|
1 month (after careful examination by 2 pathologists)
|
合作者和调查者
调查人员
- 首席研究员:Yan Yan, Doctor、Peking University Cancer Hospital & Institute
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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